HSP
HSP (Heat Shock Protein) inhibitors target HSPs, a family of molecular chaperones that assist in protein folding, stability, and protection against stress-induced damage. HSPs are often upregulated in cancer cells, helping them survive under stressful conditions such as hypoxia and chemotherapy. Inhibiting HSPs can disrupt these protective mechanisms, leading to cell death. HSP inhibitors are therefore valuable in cancer therapy and research into stress responses. At CymitQuimica, we provide a comprehensive range of high-quality HSP inhibitors to support your research in protein homeostasis, stress responses, and oncology.
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Arimoclomol maleate
CAS:289893-26-1
Arimoclomol maleate (BRX-220) (BRX-220) is a heat shock protein (HSP) co-inducer.
Formula:
C18H24ClN3O7
Purity:
99.9% - 99.98%
Color and Shape:
Solid
Molecular weight:
429.85
Ref: TM-T13554
| 5mg | 46.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 142.00 € | ||
| 50mg | 230.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Ethoxyquin
CAS:91-53-2
Ethoxyquin (Santoflex) is an antioxidant used in animal feeds.
Formula:
C14H19NO
Purity:
95.94%
Color and Shape:
Yellow Liquid Mercaptan-Like Odor (Ntp 1992)
Molecular weight:
217.31
Ref: TM-T0756
| 1g | 34.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Col003
CAS:328565-16-8
Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen-binding …
Formula:
C14H11NO4
Purity:
98.67% - 99.03%
Color and Shape:
Solid
Molecular weight:
257.24
Ref: TM-T10860
| 2mg | 46.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 105.00 € | ||
| 25mg | 213.00 € | ||
| 50mg | 343.00 € | ||
| 100mg | 531.00 € | ||
| 200mg | 761.00 € | ||
| 500mg | 1,143.00 € | ||
| 1mL*10mM (DMSO) | 70.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Novobiocin Sodium
CAS:1476-53-5
Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium …
Formula:
C31H35N2NaO11
Purity:
99% - 99.28%
Color and Shape:
Solid
Molecular weight:
634.61
Ref: TM-T0974
| 25mg | 49.00 € | ||
| 50mg | 64.00 € | ||
| 100mg | 94.00 € | ||
| 1mL*10mM (DMSO) | 48.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Rifabutin
CAS:72559-06-9
Rifabutin (LM-427), a semisynthetic ansamycin, blocks bacterial RNA synthesis by inhibiting RNA polymerase.
Formula:
C46H62N4O11
Purity:
99.27% - 99.8%
Color and Shape:
Red-Violet Crystalline Powder
Molecular weight:
847
Ref: TM-T1501
| 25mg | 49.00 € | ||
| 50mg | 60.00 € | ||
| 100mg | 85.00 € | ||
| 200mg | 136.00 € | ||
| 500mg | 222.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Radicicol
CAS:12772-57-5
Antifungal Radicicol blocks P. falciparum replication, inhibits Hsp90 (IC50: 1μM), leading to proteasomal degradation.
Formula:
C18H17ClO6
Purity:
98%
Color and Shape:
White/Yellow Powder
Molecular weight:
364.78
Ref: TM-T16719
| 1mg | 128.00 € | ||
| 5mg | 442.00 € | ||
| 500µg | 91.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Gamitrinib TPP
CAS:1131626-46-4
Gamitrinib TPP targets mitochondrial HSP90, inhibiting cancer, and blocks mitochondrial matrix.
Formula:
C52H65N3O8P
Purity:
98%
Color and Shape:
Solid
Molecular weight:
891.078
Ref: TM-T11355
| 5mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
NMS-E973
CAS:1253584-84-7
NMS-E973 is a potent and selective Hsp90 inhibitor with DC50 of <10 nM for Hsp90 …
Formula:
C22H22N4O7
Purity:
99.82%
Color and Shape:
Solid
Molecular weight:
454.43
Ref: TM-T6609
| 2mg | 41.00 € | ||
| 5mg | 62.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 191.00 € | ||
| 50mg | 300.00 € | ||
| 100mg | 428.00 € | ||
| 200mg | 601.00 € | ||
| 1mL*10mM (DMSO) | 68.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
IPI-493
CAS:64202-81-9
IPI-493 is a bioactive chemical.
Formula:
C28H39N3O8
Purity:
100%
Color and Shape:
Solid
Molecular weight:
545.62
Ref: TM-T32188
| 1mg | 274.00 € | ||
| 5mg | 673.00 € | ||
| 10mg | 920.00 € | ||
| 25mg | 1,417.00 € | ||
| 50mg | 1,846.00 € | ||
| 100mg | 2,572.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
gp96-II
Gp96-II is a gp96-blocking peptide that antagonizes cytokine production induced by gp96-mediated LPS. This compound …
Formula:
C200H353N59O53S
Color and Shape:
Liquid
Molecular weight:
4464.37
Ref: TM-TP2843
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
NDNA4
NDNA4 (compound 17) is a selective Hsp90α inhibitor (IC50: 0.34 μM), characterized by its permanent …
Formula:
C31H35F3N2O5S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
604.68
Ref: TM-T78808
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
CC-99677
CAS:1887069-10-4
CC-99677 (Gamcemetinib) is a MK2 inhibitor targeting autoimmune diseases; potent in rat assays with IC50=156.3 …
Formula:
C22H20ClN5O3S
Purity:
99.51%
Color and Shape:
Solid
Molecular weight:
469.94
Ref: TM-T39321
| 1mg | 119.00 € | ||
| 5mg | 245.00 € | ||
| 10mg | 424.00 € | ||
| 25mg | 738.00 € | ||
| 50mg | 995.00 € | ||
| 100mg | 1,386.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
PROTAC Hsp90α degrader 1
Compound X10g (PROTAC Hsp90α degrader 1) is a selective agent targeting Hsp90α for degradation and …
Formula:
C43H50N6O7
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
762.89
Ref: TM-T79323
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
Zelavespib hydrochloride
Zelavespib (PU-H71) hydrochloride is a potent inhibitor of Hsp90, exhibiting an IC50 value of 51 …
Purity:
98%
Ref: TM-T80742
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
HSP90-IN-23
HSP90-IN-23 (Comp 12-1), a heat shock protein 90 (HSP90) inhibitor, exhibits potent activity with an …
Formula:
C22H24N2O6S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
444.5
Ref: TM-T78942
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
DN401
CAS:2135749-60-7
DN401 is a potent TRAP1 and Hsp90 Inhibitor( IC50 = 79 nM for TRAP1, IC50 …
Formula:
C13H9BrClN5O2
Purity:
100%
Color and Shape:
Liquid
Molecular weight:
382.6
Ref: TM-T27193
| 1mg | 182.00 € | ||
| 5mg | 402.00 € | ||
| 10mg | 591.00 € | ||
| 25mg | 917.00 € | ||
| 50mg | 1,268.00 € | ||
| 100mg | 1,710.00 € | ||
| 500mg | 3,416.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
3-Phenyltoxoflavin
CAS:32502-63-9
3-Phenyltoxoflavin (Phenyltoxoflavin) is an inhibitor of HSP90 (Kd = 585 nM) with anti-cancer activity.
Formula:
C13H11N5O2
Purity:
98.84%
Color and Shape:
Liquid
Molecular weight:
269.26
Ref: TM-T36123
| 1mg | 57.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 185.00 € | ||
| 25mg | 332.00 € | ||
| 50mg | 503.00 € | ||
| 100mg | 741.00 € | ||
| 200mg | 1,019.00 € | ||
| 1mL*10mM (DMSO) | 131.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
PU-H71 HCl
CAS:2095432-24-7
PU-H71 HCl (Zelavespib HCl) is a novel Hsp90 inhibitor, a novel purine-based analog, and a …
Formula:
C18H22ClIN6O2S
Purity:
98%
Color and Shape:
Soild
Molecular weight:
548.83
Ref: TM-T6960L
| 1mg | 182.00 € | ||
| 5mg | 400.00 € | ||
| 10mg | 593.00 € | ||
| 25mg | 920.00 € | ||
| 50mg | 1,263.00 € | ||
| 100mg | 1,710.00 € | ||
| 500mg | 3,416.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
NCT-58
CAS:2411429-33-7
NCT-58 is a potent HSP90 inhibitor that blocks Akt, downregulates HER family, and induces apoptosis …
Formula:
C27H34N2O5
Purity:
98.75%
Color and Shape:
Solid
Molecular weight:
466.57
Ref: TM-T9996
| 1mg | 47.00 € | ||
| 5mg | 124.00 € | ||
| 10mg | 198.00 € | ||
| 25mg | 423.00 € | ||
| 50mg | 676.00 € | ||
| 100mg | 1,076.00 € | ||
| 200mg | 1,463.00 € | ||
| 1mL*10mM (DMSO) | 340.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Calyxin H
CAS:202596-22-3
Calyxin H at 1uM can increase the expression of heat shock factor 1 (HSF1), it …
Formula:
C35H34O7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
566.64
Ref: TM-TN3572
| 1mg | 236.00 € | ||
| 1mL*10mM (DMSO) | 840.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
