Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2612 products of "Chromatin/Epigenetics"
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Atractylenolide I
CAS:Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to paclitaxel.Formula:C15H18O2Purity:97.55% - 99.92%Color and Shape:SolidMolecular weight:230.30MI-463
CAS:MI-463 is a potent and orally bioavailable inhibitor of the menin-mLL interaction (IC50: 15.3 nM).Formula:C24H23F3N6SPurity:99.18% - >99.99%Color and Shape:SolidMolecular weight:484.54ABBV-744
CAS:ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS.Formula:C28H30FN3O4Purity:97.03% - >99.99%Color and Shape:SolidMolecular weight:491.55Ref: TM-T4697
1mg44.00€2mg56.00€5mg90.00€10mg142.00€25mg284.00€50mg409.00€100mg500.00€200mg718.00€1mL*10mM (DMSO)90.00€1,2-Dipalmitoyl-sn-glycerol
CAS:1,2-Dipalmitoyl-sn-glycerol ((S)-1,2-Dipalmitin) is an analog of the PKC-activating second messenger diacylglycerol (DAG). It weakly activates PKC.Formula:C35H68O5Purity:97.84% - 99.78%Color and Shape:SolidMolecular weight:568.91WP1066
CAS:WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3.Formula:C17H14BrN3OPurity:98.92% - 99.73%Color and Shape:SolidMolecular weight:356.223,6-Dihydroxyflavone
CAS:3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway.Formula:C15H10O4Purity:99.92%Color and Shape:SolidMolecular weight:254.24ML324
CAS:ML324(IC50=920 nM) is a specific inhibitor of jumonji histone demethylase (JMJD2).Formula:C21H23N3O2Purity:98.22% - 98.57%Color and Shape:SolidMolecular weight:349.43Ref: TM-T6593
2mg34.00€5mg49.00€10mg74.00€25mg122.00€50mg205.00€100mg334.00€200mg494.00€1mL*10mM (DMSO)79.00€PFI-2 hydrochloride
CAS:PFI-2 hydrochloride ((R)-PFI-2 hydrochloride) is a potent, highly selective, and cell-active inhibitor of the methyltransferase activity of SETD7 (IC50: 2 nM),Formula:C23H26ClF4N3O3SPurity:99.31% - 99.91%Color and Shape:SolidMolecular weight:535.98Ref: TM-T4583
1mg38.00€2mg49.00€5mg80.00€10mg111.00€25mg200.00€50mg358.00€100mg523.00€500mg1,108.00€1mL*10mM (DMSO)122.00€EPZ005687
CAS:EPZ005687 is a potent and selective inhibitor of EZH2.Formula:C32H37N5O3Purity:97.06% - 99.64%Color and Shape:SolidMolecular weight:539.671,5-Isoquinolinediol
CAS:1,5-Isoquinolinediol, a PARP1 inhibitor (IC50: 0.39 μM), is used in DNA repair and cell death studies.Formula:C9H7NO2Purity:98.29% - 99.35%Color and Shape:Of White To White PowderMolecular weight:161.164-amino-1,8-Naphthalimide
CAS:4-amino-1,8-Naphthalimide (4-ANI) is a PARP inhibitor with IC50 of 180 nMFormula:C12H8N2O2Purity:95.13%Color and Shape:Yellow Solid PowderMolecular weight:212.2NVP-TNKS656
CAS:NVP-TNKS656 (TNKS656) is a highly potent, selective, and orally active TNKS2 inhibitor.Formula:C27H34N4O5Purity:99.59%Color and Shape:SolidMolecular weight:494.58Ref: TM-T3261
1mg43.00€2mg54.00€5mg84.00€10mg122.00€25mg248.00€50mg421.00€100mg617.00€1mL*10mM (DMSO)93.00€Niraparib tosylate monohyrate
CAS:Niraparib (MK-4827), a PARP inhibitor, boosts DNA breaks to trigger genomic instability and apoptosis, offering anti-cancer effects.Formula:C26H30N4O5SPurity:97.7% - 99.99%Color and Shape:SolidMolecular weight:510.61Ref: TM-T9497
5mg57.00€10mg82.00€25mg111.00€50mg137.00€100mg205.00€200mg309.00€500mg515.00€1mL*10mM (DMSO)66.00€4-(3-Chlorophenyl)-2(3H)-thiazolone
CAS:4-(3-chlorophenyl)-2,3-dihydro-1,3-thiazol-2-one: a thiazole used to make antifungals, antivirals, and anti-inflammatories.Formula:C9H6ClNOSPurity:95.311%Color and Shape:SolidMolecular weight:211.67BMS-P5 free base
CAS:BMS-P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor.Formula:C27H32N6O2Purity:99.88%Color and Shape:SolidMolecular weight:472.58RBN012759
CAS:RBN012759 inhibits PARP14 protein and is more than 300-fold selective over all PARP family members.Cost-effective and quality-assured.Formula:C19H23FN2O3SPurity:98.87% - 99.96%Color and Shape:SolidMolecular weight:378.46Ref: TM-T22414
1mg104.00€2mgTo inquire5mg250.00€10mg373.00€25mg645.00€50mg938.00€100mg1,311.00€200mg1,768.00€1mL*10mM (DMSO)274.00€OSS_128167
CAS:OSS_128167 (SIRT6-IN-1) is a specific SIRT6 inhibitor, and for SIRT6(IC50=89 μM), SIRT1(IC50=1578 μM) and SIRT2(IC50=751 μM).Formula:C19H14N2O6Purity:97.47% - 98.6%Color and Shape:SolidMolecular weight:366.32AK-1
CAS:AK-1: SIRT2 inhibitor, IC50 12.5 μM, hinders Alzheimer's neurodegeneration, arrests colon cancer cell cycle.Formula:C19H21N3O5SPurity:98.32% - 99.44%Color and Shape:SolidMolecular weight:403.45BAY 87-2243
CAS:BAY 87-2243 is a potent and selective inhibitor of hypoxia-inducible factor-1 (HIF-1).Formula:C26H26F3N7O2Purity:98% - 99.95%Color and Shape:SolidMolecular weight:525.53Ref: TM-T2488
1mg35.00€2mg43.00€5mg63.00€10mg101.00€25mg212.00€50mg351.00€100mg588.00€1mL*10mM (DMSO)73.00€YF-2
CAS:YF-2 activates histone acetyltransferases (H3, CBP, PCAF, GCN5) across the blood-brain barrier; EC50s: 2.75-49.31 μM.Formula:C20H22ClF3N2O3Purity:99.33%Color and Shape:SolidMolecular weight:430.85IOX2
CAS:IOX2 is a selective HIF PHD inhibitor, active in cells with 21 nM IC50 for PHD2/ELGN-1, not inhibiting FIH at 20uM.Formula:C19H16N2O5Purity:98% - 99.59%Color and Shape:SolidMolecular weight:352.34Eicosapentaenoic Acid sodium
CAS:EPA sodium, an oral omega-3, demethylates DNA, reactivates tumor suppressors, and induces vasodilation.Formula:C20H29NaO2Color and Shape:SolidMolecular weight:324.43MS37452
CAS:MS37452 is a competitive inhibitor of CBX7 chromodomain binding to H3K27me3 (Ki = 43 µM).Formula:C22H26N2O5Purity:99.39%Color and Shape:SolidMolecular weight:398.45Ref: TM-T21767
5mg49.00€10mg84.00€25mg166.00€50mg289.00€100mg500.00€500mg1,063.00€1mL*10mM (DMSO)54.00€OTS186935 hydrochloride
OTS186935 HCl inhibits SUV39H2 (IC50 6.49 nM), curbs tumor growth in mice, and modulates γ-H2AX in cancer cells.Formula:C25H27Cl2N5O2Color and Shape:SolidMolecular weight:522.313-deazaneplanocin A HCl
CAS:3-deazaneplanocin A HCl is both an S-adenosyl-l-homocysteine hydrolase inhibitor and an enhancer of zeste homolog 2(EZH2) inhibitor.Formula:C12H15ClN4O3Purity:93.24% - 98.9%Color and Shape:SolidMolecular weight:298.73Perindopril
CAS:Perindopril, an ACE inhibitor, treats hypertension, heart failure, and coronary artery disease; available as arginine or erbumine.Formula:C19H32N2O5Color and Shape:White PowderMolecular weight:368.47HNHA
CAS:HNHA is an inhibitor of HDAC.Formula:C17H21NO2SPurity:98.04%Color and Shape:SolidMolecular weight:303.42Ref: TM-T21806
1mg44.00€5mg84.00€10mg135.00€25mg279.00€50mg445.00€100mg640.00€200mg879.00€1mL*10mM (DMSO)90.00€TIQ-A
CAS:TIQ-A blocks PARP1 to prevent excessive DNA damage response, implicated in ischemia, asthma, and atherosclerosis.Formula:C11H7NOSPurity:99.75%Color and Shape:SolidMolecular weight:201.24Ref: TM-T50098
1mg52.00€5mg92.00€10mg161.00€25mg290.00€50mg414.00€100mg532.00€200mg737.00€1mL*10mM (DMSO)96.00€4'-Methoxychalcone
CAS:4'-Methoxychalcone with a variety of pharmacological activities, such as anti-tumor and anti-inflammatory activities.Formula:C16H14O2Purity:99.86%Color and Shape:SolidMolecular weight:238.28Amodiaquine
CAS:Amodiaquine is a synthetic aminoquinoline, used to treat malaria.Formula:C20H22ClN3OPurity:99.78% - 99.99%Color and Shape:Crystals From Absolute Ethanol SolidMolecular weight:355.86Ref: TM-T8381
1mg49.00€2mg66.00€5mg90.00€10mg170.00€25mg281.00€50mg394.00€100mg550.00€1mL*10mM (DMSO)105.00€TG101209
CAS:TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.Formula:C26H35N7O2SPurity:99% - >99.99%Color and Shape:SolidMolecular weight:509.67DMOG
CAS:DMOG (Dimethyloxalylglycine), an antagonist of the α-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase.Formula:C6H9NO5Purity:80.23% - 99.98%Color and Shape:SolidMolecular weight:175.14GSK-J4 Hydrochloride
CAS:GSK-J4 Hydrochloride (GSK J4 HCl) is a cell permeable, potent and selective histone demethylase(JMJD3 )inhibitor. It is an ethyl ester derivative of the GSK-J1.Formula:C24H28ClN5O2Purity:97.95% - 98.23%Color and Shape:SolidMolecular weight:453.97Ref: TM-T4383
1mg38.00€2mg50.00€5mg84.00€10mg120.00€25mg207.00€50mg344.00€100mg505.00€200mg707.00€1mL*10mM (DMSO)132.00€YKL-06-061
CAS:YKL-06-061 is a selective salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively.Formula:C30H37N7O2Purity:99.52% - 99.79%Color and Shape:SolidMolecular weight:527.66Birabresib
CAS:Birabresib (MK-8628) is a synthetic, small molecule inhibitor of the BET (Bromodomain and Extra-Terminal) family of bromodomain-containing proteins 2, 3 and 4Formula:C25H22ClN5O2SPurity:98.3% - 99.36%Color and Shape:SolidMolecular weight:491.99Ref: TM-T6032
2mg46.00€5mg70.00€10mg90.00€25mg142.00€50mg222.00€100mg375.00€200mg560.00€500mg893.00€1mL*10mM (DMSO)74.00€BMS-P5
CAS:BMS-P5 is a specific and orally active Peptidylarginine Deiminase 4 (PAD4) inhibitor.Formula:C27H33ClN6O2Purity:99.88%Color and Shape:SolidMolecular weight:509.04Ref: TM-T22277
2mg44.00€5mg86.00€10mg136.00€25mg268.00€50mg479.00€100mg760.00€200mg1,018.00€1mL*10mM (DMSO)96.00€INCB-057643
CAS:INCB057643 is a potent, selective and orally bioavailable BET inhibitor.Formula:C20H21N3O5SPurity:99.5%Color and Shape:SolidMolecular weight:415.46Ref: TM-T5417
1mg39.00€5mg86.00€10mg133.00€25mg231.00€50mg349.00€100mg475.00€200mg652.00€1mL*10mM (DMSO)95.00€Rucaparib
CAS:Rucaparib (PF-01367338) is a orally PARP inhibitor and a H6PD inhibitor. Rucaparib exhibits antitumor activity against CRPC. Cost-effective and quality-assured.Formula:C19H18FN3OPurity:98.24% - 99.80%Color and Shape:SolidMolecular weight:323.36Ref: TM-T4463
2mg46.00€5mg70.00€10mg109.00€25mg170.00€50mg222.00€100mg344.00€200mg512.00€500mg823.00€1mL*10mM (DMSO)77.00€JW 55
CAS:JW 55 (JW55) is an effective and selective β-catenin signaling pathway inhibitor, works by inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2Formula:C25H26N2O5Purity:99.31% - 99.76%Color and Shape:SolidMolecular weight:434.48Pamiparib
CAS:Pamiparib (BGB-290) is an orally active, potent, highly selective PARP inhibitor. It has potent PARP trapping, and capability to penetrate the brain.Formula:C16H15FN4OPurity:99.69%Color and Shape:SolidMolecular weight:298.31GSK591
CAS:GSK591 (GSK3203591), Alternative Names are EPZ015866, GSK3203591, is a potent selective inhibitor of the arginine methyltransferase PRMT5 (IC50=11 nM).Formula:C22H28N4O2Purity:99.35% - 99.45%Color and Shape:SolidMolecular weight:380.48Ref: TM-T6853
1mg46.00€2mg58.00€5mg95.00€10mg137.00€25mg268.00€50mg404.00€100mg567.00€1mL*10mM (DMSO)101.00€IDF-11774
CAS:IDF-11774 is a HIF-1 inhibitor.It reduces hif-1α HRE luciferase activity (IC50 = 3.65 μM).Formula:C23H32N2O2Purity:98.05%Color and Shape:SolidMolecular weight:368.51SC99
CAS:SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.Formula:C15H8Cl2FN3OPurity:99.56%Color and Shape:SolidMolecular weight:336.15Ref: TM-T8719
1mg43.00€5mg87.00€10mg133.00€25mg227.00€50mg344.00€100mg429.00€200mg597.00€1mL*10mM (DMSO)94.00€FM-381
CAS:FM381, a JAK3 inhibitor with 127 pM IC50, is 410-3600x more selective over JAK1/2/TYK2.Formula:C24H24N6O2Purity:98.44%Color and Shape:SolidMolecular weight:428.49Ref: TM-T5091
1mg47.00€2mg62.00€5mg92.00€10mg128.00€25mg212.00€50mg319.00€100mg485.00€1mL*10mM (DMSO)107.00€Palmatine
CAS:Palmatine, also known as Burasaine, inhibits dopamine production and may treat flavivirus, jaundice, dysentery, hypertension, and liver issues.Formula:C21H22NO4Purity:96.28% - 99.49%Color and Shape:SolidMolecular weight:352.4MR837
CAS:MR837 (NSD2-PWWP1 antagonist 3f) is a NSD2-PWWP1 antagonist.Formula:C16H14N2OSPurity:99.77% - 99.85%Color and Shape:SolidMolecular weight:282.36Ref: TM-T8879
2mg38.00€5mg55.00€10mg92.00€25mg138.00€50mg243.00€100mg355.00€200mg502.00€1mL*10mM (DMSO)66.00€Benzamide
CAS:Benzamide (Amid kyseliny benzoove), an inhibitor of poly(ADP-ribose) polymerase, is a derivative of benzoic acid.Formula:C7H7NOPurity:99.66%Color and Shape:Colorless Crystals Physical Description White Powder (Ntp 1992)Molecular weight:121.14GDC-0214
CAS:GDC-0214 is an inhaled small-molecule JAK1 inhibitor and reduces fractional exhaled nitric oxide (Feno).Formula:C28H28ClF2N9O3Purity:99.75%Color and Shape:SolidMolecular weight:612.03Ref: TM-T9826
1mg93.00€5mg182.00€10mg269.00€25mg429.00€50mg610.00€100mg820.00€200mg1,099.00€1mL*10mM (DMSO)245.00€TAK-632
CAS:TAK-632 is a potent pan-Raf inhibitor.Formula:C27H18F4N4O3SPurity:98% - 99.5%Color and Shape:SolidMolecular weight:554.52KG-501
CAS:KG-501 (Naphthol AS-E phosphate) is a cAMP response element-binding protein (CREB) inhibitor(IC50 : 6.89 μM).Formula:C17H13ClNO5PPurity:97.81%Color and Shape:SolidMolecular weight:377.72MZ 1
CAS:MZ 1 is a BRD4 protein degrader based on PROTAC technology.Formula:C49H60ClN9O8S2Purity:99.31%Color and Shape:SolidMolecular weight:1002.64Tazemetostat hydrobromide
CAS:Tazemetostat hydrobromide: potent, selective EZH2 inhibitor; blocks PRC2/wild-type EZH2 (Ki: 2.5 nM) & EZH1 (IC50: 392 nM).Formula:C34H45BrN4O4Purity:99.8%Color and Shape:SolidMolecular weight:653.65Ref: TM-T17002
2mg40.00€5mg57.00€10mg77.00€50mg90.00€100mg150.00€200mg219.00€500mg358.00€1mL*10mM (DMSO)79.00€Hinokitiol
CAS:Hinokitiol prevents UVB-caused cell death, boosts antioxidant activity, and hinders breast cancer growth.Formula:C10H12O2Purity:99.49% - 99.98%Color and Shape:SolidMolecular weight:164.2Pacritinib hydrochloride
CAS:Pacritinib HCl: strong JAK2/Wild-type & JAK2V617F inhibitor (IC50: 23/19 nM), used in AML & MF research.Formula:C28H32N4O3·xClHColor and Shape:SolidKW-2449
CAS:KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.Formula:C20H20N4OPurity:98.43% - 99.69%Color and Shape:SolidMolecular weight:332.4WIKI4
CAS:WIKI4 is a potent inhibitor of Wnt/β-catenin signaling and tankyrase 2 (TNKS2).Formula:C29H23N5O3SPurity:99.6% - 99.71%Color and Shape:SolidMolecular weight:521.59FG-2216
CAS:FG-2216 (YM-311) is a HIF-prolyl hydroxylase inhibitor for the PDH2 enzyme; orally bioavailable and induced reversible and significant Epo induction in vivo.Formula:C12H9ClN2O4Purity:97.1% - >99.99%Color and Shape:SolidMolecular weight:280.66Baricitinib
CAS:Baricitinib (INCB028050) is an orally JAK1 and JAK2 inhibitor. Baricitinib has anti-inflammatory and anti-tumor activity. Cost-effective and quality-assured.Formula:C16H17N7O2SPurity:99% - >99.99%Color and Shape:SolidMolecular weight:371.42Ref: TM-T2485
5mg48.00€10mg70.00€25mg95.00€50mg109.00€100mg137.00€200mg178.00€500mg295.00€1mL*10mM (DMSO)65.00€(E/Z)-Zotiraciclib
CAS:(E/Z)-Zotiraciclib ((E/Z)-TG02) inhibits CDK2, JAK2, and FLT3 effectively with IC50s of 13, 73, and 56 nM, respectively.Formula:C23H24N4OPurity:97.75% - 99.92%Color and Shape:SolidMolecular weight:372.46Ref: TM-T21503
1mg43.00€2mg56.00€5mg93.00€10mg113.00€25mg200.00€50mg330.00€100mg480.00€1mL*10mM (DMSO)90.00€CCT 137690
CAS:CCT 137690 is a highly specific and oral-available aurora kinase inhibitor, for aurora A(IC50=15 nM ), B(IC50=25 nM) and C(IC50=19 nM).Formula:C26H31BrN8OPurity:98.51% - 99.89%Color and Shape:SolidMolecular weight:551.48UNC0642
CAS:UNC0642 is an effective and specific G9a/GLP inhibitor (IC50< 2.5 nM).Formula:C29H44F2N6O2Purity:98.75% - 99.5%Color and Shape:SolidMolecular weight:546.7Ref: TM-T4166
1mg38.00€2mg50.00€5mg82.00€10mg124.00€25mg219.00€50mg358.00€100mg537.00€200mg782.00€1mL*10mM (DMSO)89.00€AZD1208
CAS:AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.
Formula:C21H21N3O2SPurity:97.24% - 99.83%Color and Shape:SolidMolecular weight:379.48BMS-911543
CAS:BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.Formula:C23H28N8OPurity:97.69% - 99.98%Color and Shape:SolidMolecular weight:432.52Buformin hydrochloride
CAS:Buformin hydrochloride, an oral biguanide antidiabetic, activates AMPK, enhances insulin sensitivity, and inhibits hepatic glucose production.Formula:C6H16ClN5Purity:97.83%Color and Shape:SolidMolecular weight:193.68Niraparib hydrochloride
CAS:Niraparib hydrochloride (MK-4827) is a PARP inhibitor with potential cancer treatment effects, causing DNA damage and apoptosis.Formula:C19H21ClN4OPurity:99.26%Color and Shape:SolidMolecular weight:356.85G5-7
CAS:G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.Formula:C22H19F2NO3Purity:97.3%Color and Shape:SolidMolecular weight:383.39Ref: TM-T8742
1mg35.00€5mg71.00€10mg96.00€25mg172.00€50mg248.00€100mg348.00€200mg470.00€1mL*10mM (DMSO)78.00€PARP1-IN-5 dihydrochloride
CAS:PARP1-IN-5 dihydrochloride: oral, potent PARP-1 inhibitor (IC50=14.7 nM), for cancer research.Formula:C25H26Cl2N2O5SPurity:98.01%Color and Shape:SolidMolecular weight:537.46Rucaparib tartrate
CAS:Rucaparib tartrate: oral PARP-1/2/3 inhibitor, Ki=1.4 nM; also inhibits H6PD; for studying CRPC.Formula:C23H24FN3O7Color and Shape:SolidMolecular weight:473.457PFI-3
CAS:PFI-3 is a selective chemical inhibitor for SMARCA (2/4) (Kd = 89 nM)and PBI (5) bromodomains which may result in the delay and prevention of breast cancer.Formula:C19H19N3O2Purity:99.58% - 99.94%Color and Shape:SolidMolecular weight:321.37TP0463518
CAS:TP-0463518 is a highly potent HIF prolyl hydroxylase (PHD) inhibitor (IC50s: 13 nM and 18 nM for human and rat PHD2, respectively).Formula:C20H18ClN3O6Purity:99.52%Color and Shape:SolidMolecular weight:431.83FLLL32
CAS:FLLL32 is an effective JAK2/STAT3 inhibitor (IC50 of <5 μM).Formula:C28H32O6Purity:97% - 97.90%Color and Shape:SolidMolecular weight:464.55Ref: TM-T6838
2mg43.00€5mg63.00€10mg88.00€25mg117.00€50mg187.00€100mg333.00€500mg797.00€1mL*10mM (DMSO)69.00€Palmatine chloride
CAS:Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.Formula:C21H22ClNO4Purity:97.9% - 99.47%Color and Shape:SolidMolecular weight:387.86B2
CAS:B2 (Linazolamide intermediate B impurity 2) promotes inclusion formation in cellular models of Huntington's disease and Parkinson's diseaseFormula:C20H17ClN4O3Purity:99.66%Color and Shape:SolidMolecular weight:396.83Windorphen
CAS:Windorphen is a Wnt inhibitor that selectively abrogates the Wnt signaling.Formula:C17H15ClO3Purity:99.66%Color and Shape:SolidMolecular weight:302.75Fedratinib hydrochloride hydrate
CAS:Fedratinib hydrochloride hydrate (SAR 302503 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor.Formula:C27H40Cl2N6O4SPurity:98.96% - 99.87%Color and Shape:SolidMolecular weight:615.61ME0328
CAS:ME0328 is a potent and selective PARP inhibitor with IC50 of 0.89 μM for PARP3, about 7-fold selectivity over PARP1.Formula:C19H19N3O2Purity:99.22%Color and Shape:SolidMolecular weight:321.37DL-α-Hydroxyglutaric acid disodium salt
CAS:DL-α-Hydroxyglutaric acid disodium salt (disodium 2-hydroxypentanedioate) is an α -hydroxyacid formed from the hydrolysis of (R) -5-oxy-2-tetrahydrofuranFormula:C5H6Na2O5Purity:≥98%Color and Shape:SolidMolecular weight:192.08AG490
CAS:AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.Formula:C17H14N2O3Purity:98.6% - 99.85%Color and Shape:Yellow SolidMolecular weight:294.3WH-4-025
CAS:WH-4-025 is a Salt-inducible kinase (SIK) inhibitor.Formula:C39H38F3N7O5Purity:99.41%Color and Shape:SolidMolecular weight:741.76Ref: TM-T9219
1mg38.00€2mg50.00€5mg84.00€10mg130.00€25mg250.00€50mg396.00€100mg585.00€1mL*10mM (DMSO)93.00€MI-503
CAS:MI-503 is an efficient and selective Menin-MLL inhibitor. MI-503 has a significant inhibitory effect on human MLL leukemia cell line. Cost-effective and quality-assured.Formula:C28H27F3N8SPurity:99.87% - 99.99%Color and Shape:SolidMolecular weight:564.63Ref: TM-TQ0069
1mg50.00€5mg114.00€10mg178.00€25mg334.00€50mg557.00€100mg888.00€1mL*10mM (DMSO)141.00€MK-8617
CAS:MK-8617 is an orally available HIF PHD1 3 pan-inhibitor, inhibiting PHD1/2/3 (IC50: 1.0/1.0/14 nM).Formula:C24H21N5O4Purity:99.38% - >99.99%Color and Shape:SolidMolecular weight:443.45Filgotinib
CAS:Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.Formula:C21H23N5O3SPurity:98.03% - ≥95%Color and Shape:SolidMolecular weight:425.5OG-L002
CAS:OG-L002 is an effective and selective LSD1 inhibitor (IC50: 20 nM), showing 69- and 36-fold selectivity over MAO-A and MAO-B, respectively.Formula:C15H15NOPurity:97.05% - 98.62%Color and Shape:SolidMolecular weight:225.29BAZ1A-IN-1
CAS:BAZ1A-IN-1, a potent inhibitor, KD 0.52 μM against BAZ1A, is effective in high-BAZ1A cancer cells, not in low-BAZ1A ones.Formula:C16H12N4O3SPurity:99.87%Color and Shape:SolidMolecular weight:340.36Ref: TM-T9552
1mg84.00€5mg177.00€10mg268.00€25mg537.00€50mg803.00€100mg1,099.00€200mg1,468.00€1mL*10mM (DMSO)195.00€AMG-47a
CAS:AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.Formula:C29H28F3N5O2Purity:98%Color and Shape:SolidMolecular weight:535.56Danusertib
CAS:Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.Formula:C26H30N6O3Purity:97.88% - 98.79%Color and Shape:White PowderMolecular weight:474.55A-769662
CAS:A-769662 is an effective, reversible AMPK activator(EC50=0.8 μM).Formula:C20H12N2O3SPurity:97.52% - 99.58%Color and Shape:SolidMolecular weight:360.39Ref: TM-T2468
2mg37.00€5mg54.00€10mg74.00€25mg135.00€50mg244.00€100mg440.00€500mg964.00€1mL*10mM (DMSO)56.00€Amifostine sodium
CAS:Amifostine sodium is a phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.Formula:C5H15N2NaO3PSColor and Shape:SolidMolecular weight:237.21MPT0G211 mesylate
CAS:MPT0G211 mesylate: potent, selective HDAC6 inhibitor (IC50=0.291nM), oral, BBB-penetrating, anti-tau and metastasis, potential anticancer.Formula:C18H19N3O5SColor and Shape:SolidMolecular weight:389.43MM-102 TFA
CAS:MM-102 TFA is a potent WDR5/MLL inhibitor with IC50 of 2.4 nM; it disrupts MLL1-WDR5 interaction, impeding H3K4 HMT activity.Formula:C37H50F5N7O6Purity:99.4% - 99.78%Color and Shape:SolidMolecular weight:783.83Ref: TM-T8768
1mg37.00€2mg49.00€5mg100.00€10mg165.00€25mg269.00€50mg399.00€100mg587.00€1mL*10mM (DMSO)141.00€CPI-455
CAS:CPI-455 is a specific KDM5 inhibitor.Formula:C16H14N4OPurity:97.87% - 99.03%Color and Shape:SolidMolecular weight:278.31Ref: TM-T3552
1mg34.00€2mg49.00€5mg70.00€10mg105.00€25mg178.00€50mg335.00€100mg505.00€1mL*10mM (DMSO)70.00€UNC 669
CAS:UNC 669 is an effective and specific MBT (malignant brain tumor) inhibitor with IC50 of 4.2/3.1 uM for L3MBTL1/3.Formula:C15H20BrN3OPurity:97.38%Color and Shape:SolidMolecular weight:338.24G007-LK
CAS:G007-LK is a selective inhibitor of TNKS1 and TNKS2, with IC50s of 46 nM and 25 nM, respectively.Formula:C25H16ClN7O3SPurity:97.63% - 98.17%Color and Shape:SolidMolecular weight:529.96Ref: TM-T6842
1mg50.00€2mg66.00€5mg94.00€10mg158.00€25mg315.00€50mg502.00€100mg707.00€1mL*10mM (DMSO)116.00€I-CBP112
CAS:I-CBP112 is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor targeting the CBP/p300 bromodomains.Formula:C27H36N2O5Purity:98.18%Color and Shape:SolidMolecular weight:468.59Ref: TM-T3969
1mg33.00€2mg50.00€5mg92.00€10mg161.00€25mg296.00€50mg425.00€100mg583.00€200mg785.00€1mL*10mM (DMSO)92.00€C-7280948
CAS:C-7280948 is a PRMT1 inhibitor.Formula:C14H16N2O2SPurity:99.55% - ≥95%Color and Shape:SolidMolecular weight:276.35Ref: TM-T2097
5mg46.00€10mg66.00€25mg109.00€50mg178.00€100mg268.00€200mg414.00€500mg667.00€1mL*10mM (DMSO)49.00€Nexturastat A
CAS:Nexturastat A is an effective and specific HDAC6 inhibitor (IC50: 5 nM). Its selectivity is >190-fold than other HDACs.Formula:C19H23N3O3Purity:99.40% - 99.57%Color and Shape:SolidMolecular weight:341.4DR2313
CAS:DR2313 is a competitive inhibitor of poly(ADP-ribose) polymerase (IC50: 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). It also has neuroprotective.Formula:C8H10N2OSPurity:98.65%Color and Shape:SolidMolecular weight:182.24JQKD82
CAS:JQKD82 is a selective inhibitor of KDM5 and increases H3K4me3. JQKD82 can be used in studies about the treatment of multiple myeloma.Formula:C27H40N4O5Purity:100.00%Color and Shape:SolidMolecular weight:500.63Pacritinib
CAS:Pacritinib (SB1518) (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 nM, in cell-free assays).Formula:C28H32N4O3Purity:99.25% - 99.49%Color and Shape:SolidMolecular weight:472.58
