DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
Subcategories of "DNA Damage/DNA Repair"
- ATM/ATR(71 products)
- DNA Alkylation(11 products)
- DNA Methyltransferase(421 products)
- DNA gyrase(11 products)
- DNA-PK(51 products)
- MTH1(1 products)
- Nucleoside Antimetabolite/Analog(1,388 products)
- Reverse Transcriptase(43 products)
- Sirtuin(88 products)
- Telomerase(33 products)
- Topoisomerase(136 products)
Show 3 more subcategories
Found 958 products of "DNA Damage/DNA Repair"
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EDO-S101
CAS:<p>EDO-S101 (Tinostamustine) is a pan HDAC inhibitor with IC50 values of 9, 9 and 25 nM for HDAC1, HDAC2 and HDAC3 , respectively.</p>Formula:C19H28Cl2N4O2Purity:98.02% - 99.44%Color and Shape:SolidMolecular weight:415.36SCR130
CAS:<p>SCR130 (1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-) 是基于 SCR7 的 DNA 非同源末端连接抑制剂，可诱导细胞凋亡并，具有抗癌活性。 它特异性依赖连接酶 IV，抑制 DNA 的末端连接。</p>Formula:C19H13Cl2N3O2SPurity:98.9%Color and Shape:SolidMolecular weight:418.3Topovale
CAS:<p>Topovale (ARC111) is a potent inhibitor of topoisomerase I.</p>Formula:C23H23N3O5Purity:99.94%Color and Shape:SolidMolecular weight:421.45PARP1-IN-5 dihydrochloride
CAS:<p>PARP1-IN-5 dihydrochloride: oral, potent PARP-1 inhibitor (IC50=14.7 nM), for cancer research.</p>Formula:C25H26Cl2N2O5SPurity:98.01%Color and Shape:SolidMolecular weight:537.46NU6027
CAS:<p>NU6027 is a potent ATR/CDK inhibitor, inhibits CDK1/2, ATR and DNA-PK with Ki of 2.5 μM/1.3 μM, 0.4 μM and 2.2 μM, enter cells more readily than the 6-</p>Formula:C11H17N5O2Purity:98.36%Color and Shape:SolidMolecular weight:251.29Furegrelate
CAS:<p>FUREGRELATE, a thromboxane A2 (TxA2) synthase inhibitor, blunts the development of pulmonary arterial hypertension in neonatal piglets.</p>Formula:C15H11NO3Purity:99.71%Color and Shape:SolidMolecular weight:253.25AZ32
CAS:<p>AZ32 is an orally bioavailable and blood-brain barrier-penetrating ATM inhibitor with an IC50 of <6.2 nM for ATM enzyme, and an IC50 of 0.31 μM for ATM in cell.</p>Formula:C20H16N4OPurity:98.68% - 99.68%Color and Shape:SolidMolecular weight:328.37AZ9482
CAS:<p>AZ9482, a potent PARP inhibitor with 2-piperazinyl-3-cyano-pyridine linkage, causes centrosome declustering in HeLa cells with an EC50 < 18 nM.</p>Formula:C26H22N6O2Purity:99.18% - 99.86%Color and Shape:SolidMolecular weight:450.49DR2313
CAS:<p>DR2313 is a competitive inhibitor of poly(ADP-ribose) polymerase (IC50: 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). It also has neuroprotective.</p>Formula:C8H10N2OSPurity:98.65%Color and Shape:SolidMolecular weight:182.24ME0328
CAS:<p>ME0328 is a potent and selective PARP inhibitor with IC50 of 0.89 μM for PARP3, about 7-fold selectivity over PARP1.</p>Formula:C19H19N3O2Purity:99.22%Color and Shape:SolidMolecular weight:321.37γ-Oryzanol
CAS:<p>γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the</p>Formula:C40H58O4Purity:mixture - mixtureColor and Shape:White Or White Crystalline Powder OdourlessMolecular weight:602.9VE-821
CAS:<p>VE-821 (ATR Inhibitor IV) is a selective ATP competitive inhibitor of ATR( Ki/IC50: 13/26 nM in cell-free assays).</p>Formula:C18H16N4O3SPurity:97.19% - 99.97%Color and Shape:SolidMolecular weight:368.41Prulifloxacin
CAS:<p>Prulifloxacin (NM441) is a broad-spectrum fluoroquinolone that inhibits bacterial DNA synthesis by blocking topoisomerase II and IV.</p>Formula:C21H20FN3O6SPurity:99.47%Color and Shape:Yellow Or Slightly Yellow PowerMolecular weight:461.46Senaparib
CAS:<p>Senaparib (IMP4297) is a novel highly potent and selective oral PARP1/2 inhibitor with strong antitumor activity.</p>Formula:C24H20F2N6O3Purity:99.8%Color and Shape:SolidMolecular weight:478.45Levofloxacin hydrochloride
CAS:<p>Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.</p>Formula:C18H21ClFN3O4Purity:99.78% - 99.98%Color and Shape:SolidMolecular weight:397.8Pirarubicin
CAS:<p>Pirarubicin (Theprubicin), an anthracycline antibiotic, inhibits DNA/RNA synthesis and is used as an antineoplastic.</p>Formula:C32H37NO12Purity:97.80% - 99.15%Color and Shape:Red Crystalline PowderMolecular weight:627.64Ganciclovir sodium
CAS:<p>Ganciclovir sodium, a sodium salt with anti-CMV and HSV-1 antiviral properties.</p>Formula:C9H13N5NaO4Purity:99.93%Color and Shape:SolidMolecular weight:278.22AZ20
CAS:<p>AZ20 is an effective and specific inhibitor of ATR kinase (IC50: 5 nM, in a cell-free assay), 8-fold selectivity over mTOR.</p>Formula:C21H24N4O3SPurity:98% - 99.69%Color and Shape:SolidMolecular weight:412.51Triazavirin
CAS:<p>Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.</p>Formula:C5H7N6NaO5SPurity:99.55%Color and Shape:SolidMolecular weight:286.29-Hydroxycamptothecin
CAS:<p>9-Hydroxycampothecin is a camptothecin derivative with anticancer activity.</p>Formula:C20H16N2O5Purity:98.28%Color and Shape:SolidMolecular weight:364.35
