DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
Subcategories of "DNA Damage/DNA Repair"
- ATM/ATR(71 products)
- DNA Alkylation(11 products)
- DNA Methyltransferase(421 products)
- DNA gyrase(11 products)
- DNA-PK(51 products)
- MTH1(1 products)
- Nucleoside Antimetabolite/Analog(1,388 products)
- Reverse Transcriptase(43 products)
- Sirtuin(88 products)
- Telomerase(33 products)
- Topoisomerase(136 products)
Show 3 more subcategories
Found 958 products of "DNA Damage/DNA Repair"
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ITF3756
CAS:<p>ITF3756 is a selective HDAC6 inhibitor.</p>Formula:C13H11N5O2SPurity:97.74%Color and Shape:SolidMolecular weight:301.32ATR-IN-10
CAS:<p>ATR-IN-10 is a potent and highly selective inhibitor of ATR kinase (IC50: 2.978 μM).</p>Formula:C27H24N4OColor and Shape:SolidMolecular weight:420.51Hepsulfam
CAS:<p>Hepsulfam is an anticancer agent. It also displays excellent antileukemic activity (a median IC50: 0.91 μg/mL in a panel of different tumors).</p>Formula:C7H18N2O6S2Color and Shape:SolidMolecular weight:290.36CM-579
CAS:<p>CM-579 is a dual inhibitor of G9a and DNMT( IC50:16 nM, 32 nM for G9a and DNMT). It has potent in vitro cellular activity in a wide range of cancer cells.</p>Formula:C29H40N4O3Purity:99.23%Color and Shape:SolidMolecular weight:492.65C-333H
CAS:<p>C-333H is a new PPARalpha/gamma dual agonist.</p>Formula:C28H26N2O6Purity:98%Color and Shape:SolidMolecular weight:486.52F-14512
CAS:<p>F-14512, a DNA topoisomerase II inhibitor, is used potentially for the treatment of acute myeloid leukemia.</p>Formula:C33H47N5O8Color and Shape:SolidMolecular weight:641.76MHY908
CAS:<p>MHY908, a novel inhibitor of melanogenesis, potently inhibits mushroom tyrosinase activity in a dose-dependent manner.</p>Formula:C17H14ClNO3SPurity:98%Color and Shape:SolidMolecular weight:347.82S26948
CAS:<p>S26948 is a PPARγ agonist.</p>Formula:C28H25NO7SPurity:98%Color and Shape:SolidMolecular weight:519.57Topoisomerase IIα-IN-1
CAS:<p>Topoisomerase IIα-IN-1 (compound 2) is a DNA-binding ligands and a potent inhibitor of TopoIIα, a topoisomerase.</p>Formula:C22H20N4O5Color and Shape:SolidMolecular weight:420.42KRP-297
CAS:<p>KRP297 is a PPAR agonist potentially for the treatment of type 2 diabetes and dyslipidemia.</p>Formula:C20H17F3N2O4SColor and Shape:SolidMolecular weight:438.42MPT0G211
CAS:<p>MPT0G211: oral HDAC6 inhibitor with IC50=0.291 nM, 1000x selectivity, neuroprotective, anti-metastatic, crosses blood-brain barrier for Alzheimer's.</p>Formula:C17H15N3O2Purity:98% - 99.88%Color and Shape:SolidMolecular weight:293.32ST247
CAS:<p>ST247: Potent PPARβ/δ inverse agonist, blocks CCL2 expression and agonist-driven PPARβ/δ transcription, promotes co-repressor interaction.</p>Formula:C19H26N2O5S2Color and Shape:SolidMolecular weight:426.55SW155246
CAS:<p>SW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1; IC50 of 1.2 μM).</p>Formula:C16H11ClN2O5SPurity:98.99%Color and Shape:SolidMolecular weight:378.79XR 5944
CAS:<p>XR 5944 is an effective DNA binder that stabilizes topoisomerase-dependent cleavage and has shown superior efficacy in a variety of mouse and human tumor models</p>Formula:C34H34N8O2Purity:98.29% - 98.66%Color and Shape:SolidMolecular weight:586.69Huanglongmycin N
CAS:<p>Huanglongmycin N acts as a DNA topoisomerase I inhibitor, demonstrating an EC50 value of 14 μM.</p>Formula:C19H16O5Color and Shape:SolidMolecular weight:324.33DNA-PK-IN-1
CAS:<p>DNA-PK-IN-1 is a potent inhibitor of DNA-PK. DNA-PK-IN-1 has potential for cancer disease research.</p>Formula:C23H26N8O2Color and Shape:SolidMolecular weight:446.5Eicosatetraynoic acid
CAS:<p>ETYA activates PPARα/γ at 10μM, inhibits cyclooxygenase (ID50=8μM) and lipoxygenase (ID50=4μM).</p>Formula:C20H24O2Purity:98%Color and Shape:SolidMolecular weight:296.4DNA-PK-IN-3
CAS:<p>DNA-PK-IN-3 is a potent DNA-PK inhibitor, enhancing radio/chemotherapy and reducing tumors with limited side effects.</p>Formula:C19H19N9OColor and Shape:SolidMolecular weight:389.41TFMB-(S)-2-HG
CAS:<p>TFMB-(S)-2-HG (TFMB S 2 HG) is a highly effective inhibitor of TET2, the 5'-methylcytosine hydroxylase.</p>Formula:C13H11F3O4Purity:98.07%Color and Shape:SolidMolecular weight:288.22CP 775146
CAS:<p>PPARα agonist</p>Formula:C26H33NO4Purity:98%Color and Shape:SolidMolecular weight:423.54DC_501
CAS:<p>DC_501 is a selective non-nucleoside DNA methyltransferase 1 inhibitor.</p>Formula:C25H23Cl2N3OPurity:98%Color and Shape:SolidMolecular weight:452.38(S)-Gyramide A
CAS:<p>(S)-Gyramide A is a bacterial DNA gyrase inhibitor that acts by exhibiting antimicrobial activity and inhibiting bacterial cell division.</p>Formula:C21H27FN2O3SPurity:98%Color and Shape:SolidMolecular weight:406.515-Aza-4'-thio-2'-deoxycytidine
CAS:<p>5-Aza-4'-thio-2'-deoxycytidine (5-Aza-T-dCyd), a sulfur-containing deoxy-cytidine analog, serves as an orally active inhibitor of DNA methyltransferase I (DNMT1). It exhibits potential antitumor effects and DNA hypomethylating properties [1].</p>Formula:C8H12N4O3SColor and Shape:SolidMolecular weight:244.27Topoisomerase II inhibitor 4
CAS:<p>Compound E17, a topoisomerase II inhibitor, halts cell cycle at G2/M, possesses anticancer properties and cytotoxic effects.</p>Formula:C25H25N5O4Color and Shape:SolidMolecular weight:459.5Lexitropsin
CAS:<p>Lexitropsin is a novel anticancer drug.</p>Formula:C20H29N5O4Color and Shape:SolidMolecular weight:403.48ATR-IN-16
CAS:<p>ATR-IN-16 (compound 46) is an ATR kinase inhibitor with potent anticancer effects in LoVo cells, IC50 of 410 nM.</p>Formula:C19H25N7OColor and Shape:SolidMolecular weight:367.45Piroxantrone
CAS:<p>Piroxantrone (CI942; PD111815) is an anthrapyrazole antibiotic that disrupts DNA replication and repair, with limited cardiotoxicity and antineoplastic range.</p>Formula:C21H25N5O4Color and Shape:SolidMolecular weight:411.45Procarbazine free base
CAS:<p>Procarbazine: chemo drug for Hodgkin's, brain cancer; liver-activated; MAO inhibitor.</p>Formula:C12H19N3OPurity:98%Color and Shape:SolidMolecular weight:221.3MLR24
CAS:<p>MLR24 is a selective modulator of PPARγ that acts by displaying robust anti-diabetic activity.</p>Formula:C28H24F3NO6Purity:98%Color and Shape:SolidMolecular weight:527.49CAY10744
CAS:<p>CAY10744, a topoisomerase II-α inhibitor (78.9% at 20 μM), blocks cancer cell proliferation with varying IC50s and induces apoptosis in T47D cells.</p>Formula:C24H16ClNO2Color and Shape:SolidMolecular weight:385.84Anticancer agent 75
CAS:<p>Anticancer agent 75: potent, selective, less toxic to kidneys than Doxorubicin by 35x, with antiplasmodial properties.</p>Formula:C22H24N2OColor and Shape:SolidMolecular weight:332.44Givinostat hydrochloride monohydrate
CAS:<p>Givinostat hydrochloride monohydrate (ITF2357) is an HDAC inhibitor.</p>Formula:C24H27N3O4·HCl·H2OPurity:97.97% - 99.51%Color and Shape:SolidMolecular weight:475.97ZINC08438472
CAS:<p>ZINC08438472 is a selective peroxisome proliferator-activated receptors-α agonist.</p>Formula:C25H25NO8SPurity:98%Color and Shape:SolidMolecular weight:499.53Topoisomerase I inhibitor 4
CAS:<p>Topoisomerase I inhibitor 4 targets cancer cells like HepG2, A549, MCF-7, HeLa with low IC50, promising for research.</p>Formula:C23H19FN4OColor and Shape:SolidMolecular weight:386.42WEHI-150
CAS:<p>WEHI-150, a mitoxantrone analog, cross-links DNA, targets methylated CpG, halts transcription, and avoids guanine N-2 interaction.</p>Formula:C22H30N6O4Color and Shape:SolidMolecular weight:442.51Exatecan mesylate dihydrate
CAS:<p>Exatecan mesylate dihydrate (DX-8951), a DNA topoisomerase I inhibitor, exhibits an IC50 of 2.2 μM (0.975 μg/mL) and is utilized in cancer research [1] [2] [3].</p>Formula:C25H30FN3O9SPurity:98%Color and Shape:SolidMolecular weight:567.58ZINC17167211
CAS:<p>ZINC17167211 is a selective peroxisome proliferator-activated receptors-α agonist.</p>Formula:C24H17FN2O6SPurity:98%Color and Shape:SolidMolecular weight:480.46Ceralasertib formate
CAS:<p>Ceralasertib: an oral ATR kinase inhibitor that blocks CHK1 phosphorylation, disrupts DNA repair, and triggers tumor cell apoptosis.</p>Formula:C21H26N6O4SColor and Shape:SolidMolecular weight:458.54CAY10514
CAS:<p>CAY10514 is an aromatic analog of 8(S)-HETE. It acts as a dual agonist of PPARα and PPARγ with EC50 values of 0.173 and 0.642 μM, respectively.</p>Formula:C20H28O4Color and Shape:SolidMolecular weight:332.43Ranimustine
CAS:<p>Ranimustine (MCNU) can be used for polycythemia vera and chronic myelogenous leukemia research, which is a nitrosourea alkylating agent [1] [3] [4].</p>Formula:C10H18ClN3O7Color and Shape:SolidMolecular weight:327.72AA-CW236
CAS:<p>AA-CW236 is a covalent inhibitor of human O(6)-alkylguanine DNA methyltransferase (MGMT).</p>Formula:C17H16ClF3N4O2Color and Shape:SolidMolecular weight:400.78PPARδ agonist 8
CAS:<p>Pparδ agonist 8 is a potent agonist of Pparδ. Pparδ agonist 8 has potential for the study of nonalcoholic fatty liver disease (NAFLD).</p>Formula:C25H29NO5Color and Shape:SolidMolecular weight:423.5DRF 2519
CAS:<p>DRF 2519 is an activator of PPAR-alpha and PPAR-gamma.</p>Formula:C20H18N2O5SColor and Shape:SolidMolecular weight:398.43CLX 0921
CAS:<p>CLX 0921, a PPAR gamma agonist, is used potentially for the treatment of type 2 diabetes.</p>Formula:C28H25NO7SPurity:98%Color and Shape:SolidMolecular weight:519.57ARTD10/PARP10-IN-1
CAS:<p>ARTD10/PARP10-IN-1 is a PARP inhibitor that inhibits ARTD8/PARP14 and has anticancer and antitumour activity for the study of prostate cancer.</p>Formula:C12H12N2O4Purity:99.14%Color and Shape:SolidMolecular weight:248.23Gartisertib
CAS:<p>Gartisertib (VX-803) is an ATR inhibitor with anti-tumor activity, inhibiting the anti-proliferative effects induced in ccRCC cells.</p>Formula:C25H29F2N9O3Purity:99.52%Color and Shape:SolidMolecular weight:541.55NSC-311068
CAS:<p>NSC-311068: A selective TET1 inhibitor, reducing 5hmC and AML cell viability with high TET1.</p>Formula:C10H6N4O4SColor and Shape:SolidMolecular weight:278.24Daniquidone
CAS:<p>Daniquidone (Batracylin) is a potent dual inhibitor of DNA topoisomerase I and DNA topoisomerase II with cytotoxic and antiproliferative activity for neoplasms</p>Formula:C15H11N3OPurity:98.39% - 99.52%Color and Shape:SolidMolecular weight:249.27ICRF-196
CAS:<p>ICRF-196 is a Topoisomerase II Inhibitor and antineoplastic agent.</p>Formula:C12H18N4O4Color and Shape:SolidMolecular weight:282.313-Oxo-9E,11E-octadecadienoic acid
CAS:<p>13-Oxo-9E,11E-octadecadienoic acid from tomato juice, an isomer of 9-oxo-ODA, activates PPARα and lowers triglycerides in diabetic mice.</p>Formula:C18H30O3Purity:98%Color and Shape:SolidMolecular weight:294.43Tetrahydrouridine
CAS:<p>Tetrahydrouridine (NSC-112907; THU) is a multidrug resistance modulator.</p>Formula:C9H16N2O6Purity:98%Color and Shape:SolidMolecular weight:248.23DC_517
CAS:<p>DC_517 is an inhibitor of DNA methyltransferase 1 (DNMT1) ( IC50: 1.7 μM; Kd: 0.91 μM).</p>Formula:C33H35N3O2Color and Shape:SolidMolecular weight:505.65Seladelpar Lysine dihydrate
CAS:<p>Seladelpar lysine, a selective PPAR-δ agonist, is used for the therapy of Homozygous Familial Hypercholesterolemia (HoFH).</p>Formula:C27H41F3N2O9SPurity:98%Color and Shape:SolidMolecular weight:626.68BNS-22
CAS:<p>BNS-22 is a DNA topoisomerase II (Topo II) inhibitor, induces mitotic abnormalities and exhibits antiproliferative activity against human cancer cells.</p>Formula:C24H25NO5Purity:99.62%Color and Shape:SolidMolecular weight:407.46AM-3102
CAS:<p>AM-3102: An OEA analog; boosts PPARα, delays eating, resists hydrolysis, mimics OEA potency, and weakly binds CB1/CB2.</p>Formula:C21H41NO2Color and Shape:SolidMolecular weight:339.56DNA-PK-IN-4
CAS:<p>DNA-PK-IN-4, an imidazolinone, targets DNA-PKcs to hinder tumor DNA repair and induce apoptosis, showing cancer research potential.</p>Formula:C20H24N6O3Color and Shape:SolidMolecular weight:396.44G3335
CAS:<p>H-Trp-Glu-OH: Selective, reversible PPARγ modulator; cell-permeable; Kd ~8μM; potential diabetes lead.</p>Formula:C16H19N3O5Color and Shape:SolidMolecular weight:333.34SKLB-197
CAS:<p>SKLB-197 targets ATR, inhibiting it at 0.013 μM, and is inactive on 402 other kinases, showing potent antitumor effects on ATM-deficient tumors.</p>Formula:C25H24N6OColor and Shape:SolidMolecular weight:424.5ATR-IN-15
CAS:<p>ATR-IN-15, an ATR kinase inhibitor, has an IC50 of 8 nM and also targets LoVo cells, DNA-PK, and PI3K with higher IC50 values.</p>Formula:C19H22N8OColor and Shape:SolidMolecular weight:378.43PPARγ agonist 6
CAS:<p>PPARγ agonist 6 (Compound 12) is a potent agonist of selective PPARγ. PPARγ agonist 6 has potential for cancer disease research.</p>Formula:C27H26N2O4Color and Shape:SolidMolecular weight:442.51PPARγ agonist 5
CAS:<p>PPARγ agonist 5 is a selective and potent PPARγ agonist that has shown research potential for cancer disease.</p>Formula:C33H31N5OColor and Shape:SolidMolecular weight:513.63CP-67804
CAS:<p>CP 67804 enhances topoisomerase II-mediated DNA cleaving.</p>Formula:C18H13F2NO4Color and Shape:SolidMolecular weight:345.3DNA-PK-IN-7
CAS:<p>DNA-PK-IN-7 is a potent DNA-PK inhibitor (IC50= 1 nM) (WO2021104277A1, compound 5).</p>Formula:C19H21N9O2Color and Shape:SolidMolecular weight:407.43Saroglitazar
CAS:<p>Saroglitazar (Lipaglyn) is an agonist of PPAR with EC50 values of 0.65 pM and 3 nM for PPARα and PPARγ.</p>Formula:C25H29NO4SPurity:98.51%Color and Shape:SolidMolecular weight:439.5717(S)-HDHA
CAS:<p>17(S)-HDHA: A DHA derivative in human blood/cells and mouse brain; leads to 17(S)-resolvins; inhibits IL-1β and leukocyte trafficking.</p>Formula:C22H32O3Color and Shape:SolidMolecular weight:344.49ARH-049020
CAS:<p>ARH-049020, a peroxisome proliferator-activated receptor (PPAR) agonist, is used potentially for the treatment of insulin resistance and type 2 diabetes.</p>Formula:C24H31NO6Purity:97.19% - 99.82%Color and Shape:SolidMolecular weight:429.51Daltroban
CAS:<p>Daltroban (SKF 96148) is a specific thromboxane A2 (TXA2) receptor antagonist.</p>Formula:C16H16ClNO4SPurity:99.74%Color and Shape:SolidMolecular weight:353.82DNMT3A-IN-1
CAS:<p>DNMT3A-IN-1 is a potent, selective DNMT3A inhibitor with KI 9.16-18.85 μM (AdoMet) and 11.37-23.34 μM (poly dI-dC).</p>Formula:C30H38N6O4Color and Shape:SolidMolecular weight:546.66NCI172112
CAS:<p>NCI172112 is is used to develop antitumor agents effective against CNS tumors.</p>Formula:C14H23Cl2N3O2Purity:98%Color and Shape:SolidMolecular weight:336.26MD001
CAS:<p>MD001 is a PPARα/γ agonist, binds at Kds 9.55/0.14 μM, boosts transcription, and regulates glucose, lipid levels in diabetic mice.</p>Formula:C25H18O5Color and Shape:SolidMolecular weight:398.41DB-959 (salt)
CAS:<p>DB-959, a PPAR agonist, is used potentially for the treatment of Alzheimer's disease.</p>Formula:C25H27NNaO5Color and Shape:SolidMolecular weight:444.483XR-5000
CAS:<p>XR-5000 is a DNA topoisomerase I and II inhibitor.</p>Formula:C18H19N3OPurity:98%Color and Shape:SolidMolecular weight:293.36Topoisomerase II inhibitor 8
CAS:<p>Compound 22 is a potent topoisomerase II inhibitor (IC50=0.52μM), with strong anti-proliferative effects, arresting cells at G2/M.</p>Formula:C14H8N4O3SColor and Shape:SolidMolecular weight:312.36-Methyl-5-azacytidine
CAS:<p>6-Methyl-5-azacytidine is a potent DNMT inhibitor.</p>Formula:C9H14N4O5Purity:98%Color and Shape:SolidMolecular weight:258.23TZD18
CAS:<p>TZD18, a novel PPAR alpha/gamma dual agonist, inhibits cell growth and induces apoptosis in human glioblastoma T98G cells.</p>Formula:C27H27NO5SColor and Shape:SolidMolecular weight:477.57CP-67015
CAS:<p>CP 67015 has an inhibitory effect on the function of topoisomerase, and is a direct mutagen in mammalian cells, which has effects on gene and chromosome levels.</p>Formula:C17H12F2N2O3Color and Shape:SolidMolecular weight:330.29NS-220
CAS:<p>NS-220 selectively activates PPAR-alpha, reducing triglycerides and glucose in KK-Ay mice, also altering lipoproteins.</p>Formula:C21H27NO5Purity:98%Color and Shape:SolidMolecular weight:373.44Dihydro-5-azacytidine acetate
CAS:<p>Dihydro-5-azacytidine acetate (DHAC), a nucleoside analog, becomes integrated into DNA, thereby inhibiting DNA methylation, and exhibits antitumor activity [1</p>Formula:C10H18N4O7Purity:98%Color and Shape:SolidMolecular weight:306.27NU-7163
CAS:<p>NU-7163 is a potent and selective inhibitor of ATP-competitive DNA-PK.</p>Formula:C18H17NO3Purity:98%Color and Shape:SolidMolecular weight:295.33GW409544
CAS:<p>GW409544 is an agonist of PPAR-alpha and PPAR-gamma.</p>Formula:C31H30N2O5Purity:98%Color and Shape:SolidMolecular weight:510.58L-796449
CAS:<p>L-796449 is an agonist of PPAR-gamma.</p>Formula:C28H27ClO4SPurity:98%Color and Shape:SolidMolecular weight:495.03Cas9-IN-2
CAS:<p>Cas9-IN-2, an apo-Cas9 binder, inhibits Cas9 (IC50=246 μM), blocking Cas9:gRNA formation, regulating Cas9 function.</p>Formula:C21H27N5O4S2Color and Shape:SolidMolecular weight:477.6PR-104
CAS:<p>PR-104: hypoxia-activated DNA cross-linker, pre-prodrug for nitrogen mustard, converts to PR-104A in tumors.</p>Formula:C14H20BrN4O12PSColor and Shape:SolidMolecular weight:579.27RG-12525
CAS:<p>RG-12525（NID 525） is an orally available, selective and competitive leukotriene D (LTD) antagonist that inhibits LTC4, LTD4 and LTE4-induced contraction of</p>Formula:C25H21N5O2Purity:95.49%Color and Shape:SolidMolecular weight:423.47Sabarubicin
CAS:<p>Sabarubicin: a doxorubicin analogue with potent antitumor effects; superior in DNA fragmentation and topoisomerase II poisoning.</p>Formula:C32H37NO13Color and Shape:SolidMolecular weight:643.64Topoisomerase I inhibitor 6
CAS:<p>Topoisomerase I inhibitor 6 traps DNA-Top1 complex, shows low non-cancer cell cytotoxicity, and has research value.</p>Formula:C23H21N7OColor and Shape:SolidMolecular weight:411.46LT175
CAS:<p>LT175 is a dual PPARα/γ partial agonist, insulin sensitizer, orally active, with lower adipogeny (EC50: hPPARα 0.22μm, mPPARα 0.26μm, hPPARγ 0.48μm).</p>Formula:C21H18O3Color and Shape:SolidMolecular weight:318.37Romazarit
CAS:<p>Romazarit, a propionic acid derivative, is used as a PPARα agonist and acts as an antirheumatic drug.</p>Formula:C15H16ClNO4Purity:98%Color and Shape:SolidMolecular weight:309.74Pparδ agonist 7
CAS:<p>Pparδ agonist 7 is a potent agonist of Pparδ.</p>Formula:C25H25NO5Color and Shape:SolidMolecular weight:419.47Resminostat
CAS:<p>Resminostat (4SC-201) is an orally bioavailable inhibitor of histone deacetylases (HDACs) with potential antineoplastic activity.</p>Formula:C16H19N3O4SPurity:99.46%Color and Shape:SolidMolecular weight:349.4KDT 501 potassium
CAS:<p>KDT 501, a PPAR agonist and G protein-coupled receptor (GPR) 120 agonist, is used potentially for the treatment of type 2 diabetes.</p>Formula:C21H34KO5Purity:98%Color and Shape:SolidMolecular weight:405.596PPARγ agonist 4
CAS:<p>PPARγ agonist 4 (Compound 18b), a potent and selective PPARγ agonist, demonstrates antitumor efficacy only when used in conjunction with Imatinib.</p>Formula:C24H22FN3OColor and Shape:SolidMolecular weight:387.45DSO-5a
CAS:<p>DSO-5a, a potent and selective orally active BB3 agonist, is a DMAKO-00 derivative that enhances ppar-γ activity via BB3 and stimulates ERK1/2 phosphorylation.</p>Formula:C23H24N2O7Purity:98%Color and Shape:SolidMolecular weight:440.45DB-959 (free base)
CAS:<p>DB-959 is a potential agonist of PPAR.</p>Formula:C25H27NO5Color and Shape:SolidMolecular weight:421.493,6-Diamino-9(10H)-acridone
CAS:<p>3,6-Diamino-9(10H)-acridone is an inhibitor of topoisomerase [1].</p>Formula:C13H11N3OColor and Shape:SolidMolecular weight:225.25Mitobronitol
CAS:<p>Mitobronitol, a brominated mannitol analog, is an alkylating anticancer drug that aids in reducing allogeneic bone marrow transplant risks.</p>Formula:C6H12Br2O4Color and Shape:SolidMolecular weight:307.97PPARα/δ agonist 1
CAS:<p>PPARα/δ agonist 1 is a potent PPARα/PPARδ dual agonist with EC50 values of 7.0 nM for PPARα and 8.4 nM for PPARδ.</p>Formula:C22H22F3N3O5Color and Shape:SolidMolecular weight:465.42NK314
CAS:<p>NK314, a benzo[c]phenanthridine, inhibits topoisomerase II causing DNA breaks within 1h, even without proteinase K digestion.</p>Formula:C22H20ClNO4Color and Shape:SolidMolecular weight:397.85DNA-PK-IN-5
CAS:<p>DNA-PK-IN-5: potent DNA-PK inhibitor, reduces tumor repair, induces apoptosis, enhances radiotherapy, overcomes resistance.</p>Formula:C21H22N8O2Color and Shape:SolidMolecular weight:418.45Mipicoledine
CAS:<p>DM-CHOC-PEN is a DNA alkylation agent that may be used to treat brain cancer.</p>Formula:C35H48Cl5NO4Color and Shape:SolidMolecular weight:724.02NC190 sodium
CAS:<p>NC190 inhibits topoisomerase II, halts FM3A cell growth (IC50: 0.019 μg/ml in 48h), and suppresses DNA synthesis by 90% at 0.1 μg/ml.</p>Formula:C23H22N4NaO5Purity:98%Color and Shape:SolidMolecular weight:457.442BMS-711939
CAS:<p>BMS-711939: Potent PPARα agonist, EC50=4 nM, shown effective and safe in preclinical trials.</p>Formula:C22H20ClFN2O6Color and Shape:SolidMolecular weight:462.86NHC-triphosphate
CAS:<p>NHC-triphosphate is a weak alternative substrate for the viral polymerase and changes the mobility of the product in polyacrylamide electrophoresis gels.</p>Formula:C9H16N3O15P3Purity:98%Color and Shape:SolidMolecular weight:499.16Topoisomerase IIα-IN-2
CAS:<p>Topoisomerase IIα-IN-2 (compound 5) is a DNA-binding ligands and a potent inhibitor of the topoisomerase TopoIIα.</p>Formula:C22H20N4O5Color and Shape:SolidMolecular weight:420.42Naveglitazar
CAS:<p>Naveglitazar (LY 519818, LY 9818), a PPAR modulator in phase II trials for type 2 diabetes.</p>Formula:C25H26O6Color and Shape:SolidMolecular weight:422.47LY-510929
CAS:<p>LY-510929: PPAR agonist for hyperlipidemia, metabolic issues, type 2 diabetes.</p>Formula:C26H25NO5SPurity:98%Color and Shape:SolidMolecular weight:463.55HWL-088
CAS:<p>HWL-088 is a potent free fatty acid receptor 1 (FFA1/GPR40) agonist. HWL-088 significantly improves glucose tolerance in normal and diabetic models.</p>Formula:C22H19FO4Color and Shape:SolidMolecular weight:366.38CCT128930
CAS:<p>'CCT128930, potent Akt2 inhibitor (IC50=6 nM), 28x more selective over PKA.'</p>Formula:C18H20ClN5Purity:99.07% - 99.18%Color and Shape:SolidMolecular weight:341.84PluriSIn #2
CAS:<p>PluriSIn #2 is a selective topoisomerase II α (topo2α) transcription inhibitor exhibiting cytotoxicity towards undifferentiated, leukaemogenic hPSCs.</p>Formula:C11H8FN3O3Purity:98% - 99.79%Color and Shape:SolidMolecular weight:249.2HDAC-IN-5
CAS:<p>HDAC-IN-5 is a histone deacetylase (HDAC) inhibitor.</p>Formula:C26H24F3N5O2SPurity:98%Color and Shape:SolidMolecular weight:527.56Ertiprotafib
CAS:<p>Ertiprotafib (PTP 112), a PTP1B and IKK-β inhibitor, is a novel insulin sensitizer for the study of type 2 diabetes and breast cancer.</p>Formula:C31H27BrO3SPurity:98.70%Color and Shape:SolidMolecular weight:559.51Sirt2-IN-1
CAS:<p>Sirt2-IN-1 is an inhibitor of sirtuin 2 (IC50 = 163 nM).</p>Formula:C28H27N7O2S2Purity:99.57% - 99.84%Color and Shape:SolidMolecular weight:557.69CAY10767
CAS:<p>CAY10767 is a PPARα agonist with an EC50 of 37 nM; over 2700x selective against PPARγ/δ.</p>Formula:C22H20FNO3Color and Shape:SolidMolecular weight:365.4Guadecitabine sodium
CAS:<p>Guadecitabine sodium is a inhibitor of second-generation DNA methyltransferases (DNMT) .</p>Formula:C18H24N9NaO10PPurity:98%Color and Shape:SolidMolecular weight:580.407Topoisomerase I inhibitor 7
CAS:<p>Topoisomerase I inhibitor 7 (Compound 8) is a potent inhibitor of Topoisomerase I.</p>Formula:C22H19N3O5Color and Shape:SolidMolecular weight:405.4LG100754
CAS:<p>LG100754 (UVI 2112) is an insulin sensitizer and RXR modulator, antagonizing RXR homodimers while agonizing RXR:PPARα/γ heterodimers.</p>Formula:C26H36O3Color and Shape:SolidMolecular weight:396.569-Hydroxyellipticine hydrochloride
CAS:<p>9-Hydroxyellipticine hydrochloride is an inhibitor of Topo II and RyR, exhibits antitumor and antileukemic activity, and inhibits carrageenan gum-induced edema.</p>Formula:C17H15ClN2OPurity:98%Color and Shape:SolidMolecular weight:298.77Topoisomerase II inhibitor 16
CAS:<p>Topoisomerase II Inhibitor 16 (compound CT3) is a selective, orally bioavailable, and irreversible inhibitor of trypanosomal topoisomerase II, possessing the</p>Formula:C19H12F4N6OPurity:98%Color and Shape:SolidMolecular weight:416.33Topoisomerase IV inhibitor 1
CAS:<p>Compound 7d: Inhibits TOPO IV (IC50: 0.23 μM), DNA gyrase (IC50: 0.43 μM), antibacterial against S. aureus (MIC: 0.972 μM), E. coli (MIC: 0.608 μM).</p>Formula:C34H32FN7O6SPurity:98%Color and Shape:SolidMolecular weight:685.72PB131
CAS:<p>PB131, a selective and brain-permeable HDAC6 inhibitor, exhibits high binding affinity (IC50: 1.8 nM) and potent anti-inflammatory activity, making it suitable</p>Formula:C16H16FN3O2Purity:98%Color and Shape:SolidMolecular weight:301.32GW 9578
CAS:<p>GW 9578 is a PPARα agonist with potent lipid-lowering activity for the study of psoriasis, arthritis, alopecia, asthma and type I diabetes.</p>Formula:C26H34F2N2O3SPurity:98%Color and Shape:SolidMolecular weight:492.62Chiglitazar
CAS:<p>Chiglitazar is a PPAR α/γ/δ agonist and insulin sensitizer used in the treatment of type 2 diabetes mellitus , anti-inflammatory and anti-fibrotic.</p>Formula:C36H29FN2O4Color and Shape:SolidMolecular weight:572.63HDAC-IN-58
CAS:<p>HDAC-IN-58, a selective HDAC6 inhibitor, exhibits potent inhibitory activity with an IC50 of 2.06 nM, rendering it suitable for research into chronic</p>Formula:C16H13ClF2N4O3SPurity:98%Color and Shape:SolidMolecular weight:414.81Topoisomerase IV inhibitor 2
CAS:<p>Compound 5d, a potent TOPO IV inhibitor (IC50: 0.35 μM), also inhibits DNA gyrase (IC50: 0.55 μM) and has antibacterial activity.</p>Formula:C33H30FN7O6SPurity:98%Color and Shape:SolidMolecular weight:671.7HDAC ligand-1
CAS:<p>HDAC ligand-1 is a synthetic precursor utilized in the production of PROTAC-based HDAC degraders [1].</p>Formula:C7H8N2OPurity:98%Color and Shape:SolidMolecular weight:136.15ATR-IN-23
CAS:<p>ATR-IN-23 (Compound 34), a potent and selective ATR inhibitor, exhibits an IC50 of 1.5 nM, has demonstrated antiproliferative effects on LoVo cells, and induces</p>Formula:C20H22N6O3S2Purity:98%Color and Shape:SolidMolecular weight:458.56BRD 9757
CAS:<p>BRD 9757 (N-Hydroxy-1-cyclopentene-1-carboxamide) is a selective inhibitor of HDAC6 (IC50 = 30 nM).</p>Formula:C6H9NO2Purity:98.39% - 99.87%Color and Shape:SolidMolecular weight:127.14NSC16168
CAS:<p>NSC16168 is a selective ERCC1-XPF inhibitor that inhibits DNA repair and potentiates the antitumor activity of cisplatin.</p>Formula:C17H15NO9S3Purity:99.88%Color and Shape:SolidMolecular weight:473.5Dehydroepiandrosterone sulfate
CAS:<p>Dehydroepiandrosterone sulfate (PB-005) influences the migration of neurons, arborization of dendrites, and formation of new synapses.</p>Formula:C19H28O5SPurity:97.18%Color and Shape:SolidMolecular weight:368.49ISX-1
CAS:<p>ISX-1 inhibits adipogenesis and promotes osteoblastogenesis. ISX-1 can be used in studies about osteoporosis and osteopenia.</p>Formula:C14H14N4O2SPurity:98.7%Color and Shape:SolidMolecular weight:302.35Linotroban
CAS:<p>Linotroban（CL-871502） is a potent selective thromboxane (TXA2) receptor antagonist with antithrombotic activity.</p>Formula:C14H15NO5S2Purity:97.95% - >99.99%Color and Shape:SolidMolecular weight:341.4Dazmegrel
CAS:<p>Dazmegrel (UK 38,485) is a thromboxane A2 (TXA2) synthase inhibitor for the prevention of increased whole platelet aggregation in normal pregnancy.</p>Formula:C16H17N3O2Purity:98.81%Color and Shape:SolidMolecular weight:283.33Vutiglabridin
CAS:<p>Vutiglabridin (HSG4112), a PON2 modulator, is more stable and aids weight loss than Glabridin. In phase 2 trials for obesity, shows promise for PD therapy.</p>Formula:C22H26O4Purity:98.47% - 99.07%Color and Shape:SolidMolecular weight:354.44Chloroquinoxaline sulfonamide
CAS:<p>Chloroquinoxaline sulfonamide (Chloroquinoxaline) is an organic micropollutant with antimicrobial activity.</p>Formula:C14H11ClN4O2SPurity:99.79% - 99.89%Color and Shape:SolidMolecular weight:334.78DN-1289
<p>DN-1289: oral, BBB-penetrating, selectively inhibits DLK (IC50=17nM) & LZK (IC50=40nM), blocks p-c-Jun in mouse optic nerve crush.</p>Formula:C18H19F4N7O2Purity:98.56%Color and Shape:SolidMolecular weight:441.38SIRT5 inhibitor 1
CAS:<p>SIRT5 inhibitor 1 targets human Sirtuin 5 deacylase, with an IC50 of 0.11 μM, linked to aging diseases.</p>Formula:C31H39FN6O6S2Purity:97.8%Color and Shape:SolidMolecular weight:674.81Cedazuridine
CAS:<p>Cedazuridine ((4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine) is an oral inhibitor of cytidine deaminase with antineoplastic properties.</p>Formula:C9H14F2N2O5Purity:99.66%Color and Shape:SolidMolecular weight:268.21AGI-24512
CAS:<p>AGI-24512 is a inhibitor of methionine adenosyltransferase 2A (MATA2 ).It is useful for treatment of cancer and blocks growth of MTAP-deleted cancer cells in</p>Formula:C24H24N4O2Purity:98.55%Color and Shape:SolidMolecular weight:400.47Procainamide
CAS:<p>Procainamide: DNMT1 inhibitor, Class 1A antiarrhythmic, promising for cancer and arrhythmia research.</p>Formula:C13H21N3OPurity:99.92% - 99.92%Color and Shape:SolidMolecular weight:235.33L82
CAS:<p>L82: A selective, non-competitive DNA Lig1 inhibitor with anti-proliferative effects on breast cancer cells. IC50=12 μM.</p>Formula:C11H8ClN5O4Purity:97.45% - 98.91%Color and Shape:SolidMolecular weight:309.67BTB09089
CAS:<p>BTB09089 (GPR65 agonist ) is a T cell death-associated gene 8 (TDAG8/GPR65)-specific agonist.BTB09089 induces TDAG8 expression and regulates cytokine production</p>Formula:C14H12Cl2N4OS2Purity:99.78%Color and Shape:SoildMolecular weight:387.31SIRT6-IN-5
CAS:<p>SIRT6-IN-5: potent, selective SIRT6 inhibitor; IC50=34 μM; immunosuppressive, enhances chemo, boosts H3K9 acetylation, glucose uptake, curbs T-cell growth.</p>Formula:C19H14N2O6Purity:98.77%Color and Shape:SolidMolecular weight:366.32HDAC8-IN-20a
CAS:<p>HDAC8-IN-20a (HDAC8 inhibitor-20a) is a potent and selective HDAC8 inhibitor with an IC50 of 27 nM.</p>Formula:C15H15NO4Purity:98.24% - 99.22%Color and Shape:SolidMolecular weight:273.28Suksdorfin
CAS:<p>Suksdorfin has hypoglycemic effects and activates PPARγ, which promotes insulin-dependent glucose uptake by adipocytes and can be used to study obesity .</p>Formula:C21H24O7Purity:98.54%Color and Shape:SolidMolecular weight:388.41Bobcat339 hydrochloride
CAS:<p>Bobcat339 hydrochloride is a 10 11 translocation (TET) dioxygenase inhibitor that inhibits both TET1 and TET2.</p>Formula:C16H13Cl2N3OPurity:99.22%Color and Shape:SolidMolecular weight:334.2Alalevonadifloxacin
CAS:<p>Alalevonadifloxacin is a DNA gyrase and DNA topoisomerase inhibitor and a novel antibacterial compound of the quinolone class targeting MRSa.</p>Formula:C23H30FN3O8SPurity:99.75% - 99.82%Color and Shape:SoildMolecular weight:527.56Pegamotecan
CAS:<p>Pegamotecan (PEG-camptothecin) is a topoisomerase I (TOP1) inhibitor with anticancer activity, and it is used in the treatment of esophageal, non-small cell</p>Formula:C52H48N6O14Purity:96.40% - 97.83%Color and Shape:SolidMolecular weight:980.984Miriplatin hydrate
CAS:Miriplatin hydrate (SM-11355 (hydrate)) (MPT) is a novel platinum complex used in TACE that shows promise for the treatment of hepatocellular carcinoma (HCC).Formula:C34H70N2O5PtPurity:99.6%Color and Shape:SolidMolecular weight:782.01BRD6688
CAS:<p>BRD6688 is a selective HDAC2 inhibitor that acts by enhancing the learning and memory processes</p>Formula:C16H18N4OPurity:97.53%Color and Shape:SolidMolecular weight:282.34PARP10-IN-2
CAS:<p>PARP10-IN-2 is a potent inhibitor of PARP10, a mono-ADP-ribosyltransferase, with an IC50 value of 3.64 μM for human PARP10.PARP10-IN-2 also inhibited PARP2 and</p>Formula:C14H10N2O2Purity:99.27%Color and Shape:SolidMolecular weight:238.24Tenifatecan
CAS:<p>Tenifatecan (SN2310) is a highly lipophilic preparation of 7-ethyl-10-hydroxycamptothecin (SN) with potential antitumor activity.</p>Formula:C55H72N2O9Purity:99.58% - 99.82%Color and Shape:SolidMolecular weight:905.17SS-208
CAS:<p>SS-208 is a selective inhibitor of HDAC6 (IC50 = 12 nM) with anti-tumor activity. SS-208 shows selectivity over other HDAC subtypes.</p>Formula:C13H11Cl2N3O4Purity:99.69%Color and Shape:SolidMolecular weight:344.15(R)-(-)-Rolipram
CAS:<p>(R)-(-)-Rolipram ((-)-Rolipram) is an R-enantiomer of Rolipram which is a PDE4 inhibitor.</p>Formula:C16H21NO3Purity:99.54%Color and Shape:SolidMolecular weight:275.34Givinostat hydrochloride
CAS:<p>Givinostat HCl (ITF2357 HCl) inhibits HDAC1/3 (IC50: 198/157 nM) with anti-inflammatory, anti-angiogenic, and antineoplastic properties.</p>Formula:C24H28ClN3O4Purity:99.39%Color and Shape:SolidMolecular weight:457.95EB-47
CAS:<p>EB-47 imitates NAD+, spans nicotinamide to adenosine sites, inhibits PARP-1 (IC50: 45 nM) and is less effective on ARTD5 (IC50: 410 nM).</p>Formula:C24H27N9O6Purity:99.81%Color and Shape:SolidMolecular weight:537.53CEP-9722
CAS:<p>CEP-9722 is a PARP-1 and PARP-2 inhibitor with anticancer activity and is used in the study of ovarian cancer.</p>Formula:C24H26N4O3Purity:98.38% - 98.56%Color and Shape:SolidMolecular weight:418.49ACY-957
CAS:<p>ACY-957: Oral HDAC1/2 inhibitor (IC50: HDAC1=7nM, HDAC2=18nM, HDAC3=1300nM); inactive on HDAC4/5/6/7/8/9.</p>Formula:C24H23N5OSPurity:99.79%Color and Shape:SolidMolecular weight:429.54OUL232
CAS:<p>OUL232 is a potent single ARTs PARP7, PARP10, PARP11, PARP12, PARP14 and PARP15 inhibitor for cancer and tumour research.</p>Formula:C10H10N4O2SPurity:99.04%Color and Shape:SolidMolecular weight:250.28ACY-1083
CAS:<p>ACY-1083 is a selective and brain-penetrating HDAC6 inhibitor (IC50: 3 nM) and effectively reverses chemotherapy-induced peripheral neuropathy.</p>Formula:C17H18F2N4O2Purity:99.19% - 99.43%Color and Shape:SolidMolecular weight:348.35BRD4097
CAS:<p>BRD4097, a negative control in the HDAC1/2/3/8 assay, is a selective histone deacetylase (HDAC3) inhibitor that can be used to protect b-cells and improve</p>Formula:C16H17N3O2Purity:99.75%Color and Shape:SolidMolecular weight:283.33BRD2492
CAS:<p>BRD2492 is an HDAC1 and HDAC2 inhibitor with antiproliferative activity, inhibits HDAC1/2 and induces apoptosis.</p>Formula:C20H18N4O2Purity:99.56%Color and Shape:SolidMolecular weight:346.38KRP-101
CAS:<p>KRP-101, a PPARɑ agonist, is used potentially for the treatment of diabetes and hyperlipidaemia.</p>Formula:C26H26FNO5Color and Shape:SolidMolecular weight:451.49PPARγ agonist 7
CAS:<p>PPARγ agonist 7 (Compound 3a) is a highly potent and selective agonist of the peroxisome proliferator-activated receptor gamma (PPARγ).</p>Formula:C20H30O6Color and Shape:SolidMolecular weight:366.45K-756
CAS:<p>K-756 is a direct and selective inhibitor of tankyrase (TNKS), which inhibits the ADP-ribosylation activity of TNKS1 (IC50 = 31 nM) and TNKS2 (IC50 = 36 nM).</p>Formula:C24H27N5O3Purity:99.81%Color and Shape:SolidMolecular weight:433.5L-783483
CAS:<p>L-783483 is an agonist of PPAR.</p>Formula:C22H21ClF3NO4SPurity:98%Color and Shape:SolidMolecular weight:487.92ATR-IN-21
CAS:<p>ATR-IN-21, also known as compound 60, is a potent inhibitor of ATR, exhibiting an IC50 of less than 1000 nM [1].</p>Formula:C23H27N7OPurity:98%Color and Shape:SolidMolecular weight:417.51HDAC8-IN-4
CAS:<p>HDAC8-IN-4 is a selective HDAC8 inhibitor, exhibiting inhibitory activity with IC50 values of 0.15 μM for HDAC8 and 12 μM for HDAC3 [1].</p>Formula:C17H14N2O2S2Purity:98%Color and Shape:SolidMolecular weight:342.44Duocarmycin analog-2
CAS:<p>Duocarmycin analog-2 is a potent DNA alkylating agent that exhibits antitumor effects and can be used in the synthesis of immunocouplers.</p>Formula:C29H23ClN4O3Color and Shape:SolidMolecular weight:510.97GNE-8505
CAS:<p>GNE-8505 is an orally available inhibitor of Dual leucine zipper kinase (DLK).</p>Formula:C21H24F3N5OColor and Shape:SolidMolecular weight:419.44CM-579 trihydrochloride (1846570-40-8 free base)
<p>CM-579 trihydrochloride is a first-in-class reversible and dual inhibitor of G9a and DNMT (IC50s: 16 nM, 32 nM) with potent in vitro cellular activity in a wide</p>Formula:C29H43Cl3N4O3Purity:98%Color and Shape:SolidMolecular weight:602.04LCB-2853
CAS:<p>LCB-2853 is a potent thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor antagonist with antiplatelet aggregation, antivasospasm, and antithrombotic effects.</p>Formula:C21H24ClNO4SPurity:97.15%Color and Shape:SolidMolecular weight:421.94ARN-21934
CAS:<p>ARN-21934 inhibits human topoisomerase II α/β; IC50=2μM; stronger than Etoposide (IC50=120μM) in DNA relaxation.</p>Formula:C21H24N6Purity:99.8%Color and Shape:SolidMolecular weight:360.46XY-4
CAS:<p>XY-4, a derivative of 1-palmitoyl lysophosphatidic acid (1-palmitoyl LPA094) and an agonist of peroxisome proliferator-activated receptor γ (PPARγ), effectively</p>Formula:C19H37F2O6PColor and Shape:SolidMolecular weight:430.46Bocodepsin hydrochloride
CAS:<p>Bocodepsin hydrochloride (OKI-179) is a selective HDAC inhibitor with antitumor properties, efficacious via oral administration.</p>Formula:C26H40ClN5O6S2Purity:98%Color and Shape:SolidMolecular weight:618.21TP0480066
CAS:<p>TP0480066 inhibits topoisomerase II, DNA gyrase (IC50=1.1nM), topo IV (IC50=62.89nM), effective against drug-resistant bacteria and N. gonorrhoeae.</p>Formula:C18H14FN3O5Color and Shape:SolidMolecular weight:371.32Topoisomerase IIα-IN-8
CAS:<p>Topoisomerase IIα-IN-8 (compound 15) serves as a modest inhibitor of human DNA topoisomerase IIα (htIIα), exhibiting an inhibitory concentration (IC50) of 462 ± 38.0 μM [1].</p>Formula:C15H15FN6OColor and Shape:SolidMolecular weight:314.324ATR-IN-13
CAS:<p>ATR-IN-13 is a potent inhibitor of ATR kinases (IC50: 2 nM) and can be used to study ATR kinase-mediated diseases (e.g. proliferative diseases, cancer).</p>Formula:C24H24FN9OColor and Shape:SolidMolecular weight:473.51GSK-3484862
CAS:<p>Gsk-3484862 is a non covalent inhibitor of DNA methyltransferase DNMT1 with anticancer activity.</p>Formula:C19H19N5OSPurity:99.87% - 99.963%Color and Shape:SolidMolecular weight:365.45Peliglitazar
CAS:<p>Peliglitazar is a activator of α/γ peroxisome proliferator-activated receptor.</p>Formula:C30H30N2O7Color and Shape:SolidMolecular weight:530.57SR 2595
CAS:<p>SR2595 is an inverse agonist of nuclear receptor PPARγ with an IC 50 of 30 nM [1].</p>Formula:C37H38N2O3Color and Shape:SolidMolecular weight:558.71BMS-250749
CAS:<p>BMS-250749 is a fluoroglycosylated fluoroindolocarbazole, it has antitumor activity.</p>Formula:C26H18F3N3O6Purity:98%Color and Shape:SolidMolecular weight:525.43HDAC6-IN-21
CAS:<p>HDAC6-IN-21 (compound 13) is an irreversible inhibitor of histone deacetylase 6 (HDAC6) [1].</p>Formula:C14H13F2N5O2Purity:98%Color and Shape:SolidMolecular weight:321.28DS-6930
CAS:<p>DS-6930 is an potent and selective PPAR γ Agonists with EC50 of 41 nM.</p>Formula:C23H21N3O4Color and Shape:SolidMolecular weight:403.43CM-675
CAS:<p>CM-675 is a dual inhibitor of phosphodiesterase 5 (PDE5) and class I histone deacetylases (IC50s: 114 nM and 673 nM for PDE5 and HDAC1) with the potential to</p>Formula:C31H32N6O3Purity:99.82%Color and Shape:SolidMolecular weight:536.62SIRT6-IN-3
CAS:<p>SIRT6-IN-3 (compound 8a), a selective SIRT6 inhibitor (IC50 = 7.49 μM), impedes the proliferation of pancreatic ductal adenocarcinoma (PDAC) cells and prompts</p>Formula:C21H30Br3ClN6SPurity:98%Color and Shape:SolidMolecular weight:673.73Makaluvamine A
CAS:<p>Makaluvamine A comes from the fruiting bodies of Didymium bahiense that act as active anti-cancer agents and DNA topo II inhibitors.</p>Formula:C11H11N3OColor and Shape:SolidMolecular weight:201.22Tankyrase-IN-5
CAS:<p>Tankyrase-IN-5 (Compound 30f), structurally related to MSC2504877, effectively inhibits tankyrase isoforms TNKS1 and TNKS2, with half-maximal inhibitory</p>Formula:C17H18N2O2Purity:98%Color and Shape:SolidMolecular weight:282.34SU-11752
CAS:<p>SU-11752 selectively inhibits DNA-PK by competing with ATP, enhances ionizing radiation sensitivity without affecting cell cycle or ATM activity.</p>Formula:C26H27N3O5SColor and Shape:SolidMolecular weight:493.57Pparδ agonist 1
CAS:<p>Pparδ agonist 1 is an agonist of PPAR-δ(EC50 of 5.06 nM).</p>Formula:C26H27NO5Purity:98%Color and Shape:SolidMolecular weight:433.5U-46619
CAS:<p>U-46619 is an effective thromboxane A2 (TXA2) agonist and a thromboxane A2 analog (endoperoxide), capable of inducing contraction in the aortic smooth muscle (</p>Formula:C21H34O4Purity:98%Color and Shape:SolidMolecular weight:350.49ATR-IN-20
<p>ATR-IN-20: potent ATR inhibitor, IC50=3nM; inhibits mTOR, IC50=18nM; selective vs PI3Kα, ATM, DNA-PK; good pharmacokinetics; anticancer.</p>Formula:C29H31N5O4SColor and Shape:SolidMolecular weight:545.65CAY10410
CAS:<p>CAY10410 is a PGD2/PGJ2 analog, modified for enhanced PPARγ activity and metabolic stability, non-toxic to SH-SY5Y cells at ≤25μM.</p>Formula:C20H30O3Color and Shape:SolidMolecular weight:318.45LMP744 hydrochloride
CAS:<p>LMP744 hydrochloride (NSC-706744 hydrochloride) is a DNA intercalator and Topoisomerase I (Top1) inhibitor with antitumor activity. </p>Formula:C24H25ClN2O7Purity:99.59% - 99.85%Color and Shape:SolidMolecular weight:488.92AZ 5704
CAS:<p>ATM kinase inhibitor with 0.6 nM IC50, >600-fold selective, enhances irinotecan effects, oral use.</p>Formula:C23H23FN6O2Color and Shape:SolidMolecular weight:434.479A1P9
CAS:<p>9A1P9, a multi-tail ionizable cationic phospholipid, facilitates membrane destabilization and is applicable for CRISPR-Cas9 gene editing in mice [1].</p>Formula:C27H58NO4PColor and Shape:SolidMolecular weight:491.73BO 2367
CAS:<p>BO 2367, a topoisomerase inhibitor, is used to suppress the growth of tumor .</p>Formula:C21H22ClF2N3O3Color and Shape:SolidMolecular weight:437.87ATR-IN-22
CAS:<p>ATR-IN-22 (Compound 34), an orally active ATR inhibitor, exhibits potent anti-proliferative effects on MIAPaCa-2 cells with an IC50 value of less than 1 μM and</p>Formula:C25H31N7OPurity:98%Color and Shape:SolidMolecular weight:445.56ATR-IN-5
CAS:<p>ATR-IN-5 is a potent inhibitor of ATR, a member of the PIKK family of proteins involved in genome stability and DNA damage repair.</p>Formula:C27H32F3N9OColor and Shape:SolidMolecular weight:555.6Topoisomerase I inhibitor 9
CAS:<p>Topoisomerase I Inhibitor 9 (compound 3d), a specific inhibitor of leishmanial topoisomerase IB, exhibits antileishmanial activity, demonstrating an IC50 value</p>Formula:C23H15Br2FN2Purity:98%Color and Shape:SolidMolecular weight:498.19Topoisomerase inhibitor 2
CAS:<p>Topoisomerase Inhibitor 2 (18C) is a broad-spectrum bacterial topoisomerase inhibitor effective against multidrug-resistant Gram-negative bacteria [1].</p>Formula:C23H23N5O4Purity:98%Color and Shape:SolidMolecular weight:433.46
