DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
Subcategories of "DNA Damage/DNA Repair"
- ATM/ATR(71 products)
- DNA Alkylation(21 products)
- DNA Methyltransferase(450 products)
- DNA gyrase(6 products)
- DNA-PK(50 products)
- MTH1(1 products)
- Nucleoside Antimetabolite/Analog(341 products)
- Reverse Transcriptase(41 products)
- Sirtuin(91 products)
- Telomerase(33 products)
- Topoisomerase(126 products)
Show 3 more subcategories
Found 840 products for "DNA Damage/DNA Repair".
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Enoxacin
CAS:Enoxacin (NSC-629661) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.Formula:C15H17FN4O3Purity:99.60% - 99.89%Color and Shape:White SolidMolecular weight:320.32Telomerase-IN-2
CAS:Telomerase-IN-2 (Telomerase inhibitor 2) shows potent inhibitory activity against telomerase by decreasing the expression of dyskerin (IC50: 0.89 µM).Formula:C34H39N3O9Purity:99.32%Color and Shape:White SolidMolecular weight:633.69Chlorambucil
CAS:Chlorambucil (CB-1348) is an orally-active antineoplastic aromatic nitrogen mustard.Formula:C14H19Cl2NO2Purity:97.37% - 98.45%Color and Shape:Off-White Slightly Granular Powder Melting Point 65-69°CMolecular weight:304.21G150
CAS:G150 suppresses DSDNA-induced interferon; IC50: 10.2 nM. It's a potent, selective H-CGAS inhibitor.Formula:C18H16Cl2N4O2Purity:97.75%Color and Shape:White SolidMolecular weight:391.25Ref: TM-T11344
1mg119.00€5mg248.00€1mL*10mM (DMSO)270.00€10mg356.00€25mg612.00€50mg797.00€100mg1,035.00€Oxaquin TEA
Oxaquin TEA (MCB-3837 TEA), a precursor compound to MCB3681, is a DNA topoisomerase inhibitor that can be used to study Clostridium difficile infections andFormula:C37H48F2N5O11PPurity:99.53%Color and Shape:SolidMolecular weight:807.77Mavodelpar free acid hydrochloride
Mavodelpar free acid hydrochloride (Pparδ agonist HCl) is a potent PPARδ agonist.Formula:C31H31ClFNO5Purity:98.13%Color and Shape:SolidMolecular weight:552.03Ref: TM-T12527L
1mg296.00€5mg718.00€10mg982.00€1mL*10mM (DMSO)1,035.00€25mg1,485.00€50mg2,008.00€100mg2,637.00€Abacavir
CAS:Abacavir (Ziagen) is a nucleoside reverse transcriptase inhibitor analog of guanosine.Formula:C14H18N6OPurity:99.36% - 99.81%Color and Shape:SolidMolecular weight:286.33Ref: TM-T1267
5mg34.00€1mL*10mM (DMSO)48.00€10mg49.00€25mg73.00€50mg95.00€100mg109.00€200mg137.00€500mg221.00€1g326.00€NTP42
CAS:NTP42 is an antagonist of thromboxane A2 (TXA2) receptor(IC50 of 3.278 nM)Formula:C25H23F2N3O5SPurity:97.55%Color and Shape:SolidMolecular weight:515.53Ref: TM-T12268
1mg59.00€2mg86.00€5mg133.00€1mL*10mM (DMSO)150.00€10mg203.00€25mg344.00€50mg512.00€100mg735.00€5-Azacytidine
CAS:5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity.Formula:C8H12N4O5Purity:99.31% - 99.87%Color and Shape:White SolidMolecular weight:244.2LY518674
CAS:LY518674 (LY-674) decreases triglycerides and increases HDL-C and is used for the treatment of atherosclerosis.Formula:C23H27N3O4Purity:98.87%Color and Shape:SolidMolecular weight:409.48Ref: TM-T15821
1mg167.00€5mg340.00€1mL*10mM (DMSO)376.00€10mg505.00€25mg802.00€50mg1,099.00€100mg1,485.00€Cisplatin
CAS:Cisplatin (CDDP) is a DNA cross-linking agent.Formula:Cl2H6N2PtPurity:97.13% - 99.63%Color and Shape:SolidMolecular weight:300.04Altretamine
CAS:Altretamine (ENT-50852) is an alkylating agent with antineoplastic activity.Formula:C9H18N6Purity:99.54%Color and Shape:White SolidMolecular weight:210.28Tallimustine HCl
CAS:Tallimustine HCl, an AT-specific alkylating agent, treats leukemia in immunodeficiency mouse models.Formula:C32H39Cl3N10O4Purity:99.62%Color and Shape:SoildMolecular weight:734.08LTURM34
CAS:LTURM34 is an inhibitor of DNA-PK with IC50 of 34 nM.Formula:C24H18N2O3SPurity:99.34%Color and Shape:White SolidMolecular weight:414.48Ref: TM-T15789
5mg43.00€1mL*10mM (DMSO)47.00€10mg71.00€25mg138.00€50mg231.00€100mg344.00€200mg505.00€Fleroxacin
CAS:Fleroxacin (RO 23-6240) is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase.Formula:C17H18F3N3O3Purity:99.58% - 99.79%Color and Shape:White SolidMolecular weight:369.34DC-05
CAS:DC-05 is an inhibitor of DNA methyltransferase 1 (DNMT1) (IC50 and a Kd: 10.3 μM and 1.09 μM, respectively).Formula:C25H25N3OPurity:98.95%Color and Shape:SolidMolecular weight:383.49Ref: TM-T15080
1mg66.00€5mg145.00€1mL*10mM (DMSO)158.00€10mg236.00€25mg515.00€50mg858.00€100mg1,251.00€200mg1,684.00€FEN1-IN-1
CAS:FEN1-IN-1 (LNT-1), a FEN1 active site inhibitor, partly works by coordinating Mg2+ ions.Formula:C15H12N2O5SPurity:99.72% - 99.93%Color and Shape:White SolidMolecular weight:332.33Cloxiquine
CAS:Cloxiquine (Dermofongin) is a monohalogenated 8-hydroxyquinoline with activity against bacteria, fungi, and protozoa.Formula:C9H6ClNOPurity:99.82% - 99.87%Color and Shape:SolidMolecular weight:179.6Clofibric acid
CAS:Clofibric acid (Chlorofibrinic acid) is an antilipemic agent that is the biologically active metabolite of CLOFIBRATE.Formula:C10H11ClO3Purity:99.47% - 99.8%Color and Shape:White SolidMolecular weight:214.65NSC 31150
CAS:Indomethacin sodium hydrate (Indometacin sodium hydrate) is a COX1/2 inhibitor that induces migraine headaches and may be used in studies of rheumatoid joints.Formula:C10H5Cl2NO2SPurity:99.06%Color and Shape:SolidMolecular weight:274.12Lomefloxacin
CAS:Lomefloxacin (SC47111A) is a synthetic broad-spectrum fluoroquinolone with antibacterial activity.Formula:C17H19F2N3O3Purity:98.59% - 99.88%Color and Shape:Off-White To Yellow CrystalsMolecular weight:351.35Arhalofenate
CAS:Arhalofenate (JNJ 39659100) is a selective partial agonist of peroxisome proliferator-activated receptor PPARγ. It is used for the treatment of type 2 diabetes.Formula:C19H17ClF3NO4Purity:98.97%Color and Shape:SolidMolecular weight:415.79Ref: TM-T16022
1mg58.00€5mg193.00€1mL*10mM (DMSO)256.00€10mg340.00€25mg557.00€50mg782.00€100mg1,054.00€200mg1,423.00€Foscarnet sodium
CAS:Foscarnet sodium (Phosphonoformate) is an antiviral agent used in the treatment of cytomegalovirus retinitis.Formula:CNa3O5PPurity:98.52%Color and Shape:White SolidMolecular weight:191.95Fenofibric acid
CAS:Fenofibric acid (FNF acid) is the active form of fenofibrate, a synthetic phenoxy-isobutyric acid derivate with antihyperlipidemic activity.Formula:C17H15ClO4Purity:99.36%Color and Shape:White SolidMolecular weight:318.75N-(1-(3,4-Dihydroxyphenyl)propan-2-yl)oleamide
CAS:N-(1-(3,4-Dihydroxyphenyl)propan-2-yl)oleamide: binds CB1 (Ki=365 nM), activates PPARα (EC50=698 nM), reduces rat food intake, no FAAH inhibition.Formula:C27H45NO3Color and Shape:SolidMolecular weight:431.661ACT-387042
CAS:ACT-387042 is a Bacterial Topoisomerase Inhibitor, it has broad-spectrum activity against Gram-positive and Gram-negative bacteria.Formula:C23H26FN5O4SColor and Shape:SolidMolecular weight:487.55AZD-5099
CAS:AZD-5099 is a DNA gyrase modulator potentially for the treatment of bacterial infection.Formula:C21H27Cl2N5O6SColor and Shape:SolidMolecular weight:548.44(S)-Kaempferide
(S)-Kaempferide (ZINC167686681) is a DNA methyltransferase (DNMT) inhibitor used in tumor research.Formula:C16H12O6Color and Shape:SolidMolecular weight:300.06339DNMT2-IN-1
DNMT2-IN-1 (compound 80) is a novel DNMT2 (DNA methyltransferase 2) inhibitor with an IC50 of 1.2 μM, intended for research in neurological and metabolic disorders or cancer.Formula:C20H23BrN8O9SC2HF3O2Molecular weight:744.04207Sulotroban
CAS:sulotroban is a TXA2 receptor antagonist that acts synergistically with iloprost to inhibit TXA2-dependent platelet activation.Formula:C16H17NO5SPurity:98.86% - 99.98%Color and Shape:SolidMolecular weight:335.37Multi-target kinase inhibitor 4
Multi-target kinase inhibitor 4 (Compound 2) is a PI3K/DNA-PK inhibitor and a potent chemosensitizer that enhances the number of DNA double-strand breaks induced by Doxorubicin. It serves as an effective multidrug resistance (MDR) inhibitor, demonstrating inhibitory activity against P-glycoprotein (P-gp) mediated drug efflux. Multi-target kinase inhibitor 4 can be encapsulated in PEG-coated lipid nanoparticles.Color and Shape:Odour SolidLarsucosterol Ammonium salt
CAS:Larsucosterol ammonium salt is a derivative of 25HC3S. It is a DNMT inhibitor, a LXR antagonist, an endogenous epigenetic modulator of lipid metabolism.Formula:C27H49NO5SPurity:>99.99% - >99.99%Color and Shape:SolidMolecular weight:499.75Hippeastrine
CAS:Hippeastrine is an alkaloid that inhibits Top I dose-dependently with a 7.25 μg/mL IC50 and has anticancer properties.Formula:C17H17NO5Color and Shape:SolidMolecular weight:315.32IC 86621
CAS:IC 86621: DNA-PK ATP-competitive inhibitor, IC50 120 nM, enhances DSB antitumor effects, EC50 68 µM for repair.Formula:C12H15NO3Purity:99.68%Color and Shape:SolidMolecular weight:221.25(iso)-BRD20322
CAS:(iso)-BRD20322 is an isomer of BRD20322, a novel potent inhibitor of spCas9，disrupts the binding of spCas9 to DNA and reduces non-specific DNA editing events.Formula:C27H31N3O2Purity:99.60% - 99.60%Color and Shape:SolidMolecular weight:429.55CP 84364
CAS:CP 84364 is a metabolite of CP-80794.Formula:C14H18N2O4Color and Shape:SolidMolecular weight:278.30Hippeastrine Hydrobromide
CAS:Hippeastrine hydrobromide is a natural alkaloid which demonstrates significant cytotoxicity against a panel of human and murine tumor cell lines.Formula:C17H18BrNO5Color and Shape:SolidMolecular weight:396.237TAS-103
CAS:TAS-103 is a dual inhibitor of DNA topoisomerase I/II, used for cancer research.Formula:C20H19N3O2Color and Shape:SolidMolecular weight:333.38Berzosertib
CAS:Berzosertib (VE-822) is an ATR inhibitor (Ki<0.2 nM) that also inhibits ATM (Ki=34 nM). Berzosertib has antitumor activity. Cost-effective and quality-assured.Formula:C24H25N5O3SPurity:97.34% - >99.99%Color and Shape:SolidMolecular weight:463.55Ref: TM-T2669
1mg34.00€5mg71.00€1mL*10mM (DMSO)73.00€10mg96.00€25mg146.00€50mg213.00€100mg340.00€200mg497.00€500mg790.00€Nanaomycin A
CAS:Nanaomycin A, a quinone antibiotic, reactivates cancer suppressor genes and inhibits DNMT3B (IC50=500nM).Formula:C16H14O6Purity:98%Color and Shape:Yellow SolidMolecular weight:302.28Saroglitazar Magnesium
CAS:Saroglitazar Magnesium: a PPAR agonist, strong on PPARα (EC50 0.65pM), moderate on PPARγ (EC50 3nM).Formula:C50H56MgN2O8S2Purity:99.40%Color and Shape:SolidMolecular weight:901.43Ref: TM-T12834
1mg54.00€5mg126.00€10mg178.00€1mL*10mM (DMSO)178.00€25mg309.00€50mg416.00€100mg532.00€DMT-dG(ib) Phosphoramidite
CAS:DMT-dG(ib) Phosphoramidite can be used to synthesize DNA.Formula:C44H54N7O8PPurity:99.21%Color and Shape:SolidMolecular weight:839.92GJ071 oxalate
CAS:GJ071 oxalate is a Nonsense suppressor that induces readthrough by inserting amino acids at premature termination codons.Formula:C20H29N3O7SPurity:99.93%Color and Shape:White SolidMolecular weight:455.53Ref: TM-T31932
1mg73.00€5mg149.00€1mL*10mM (DMSO)166.00€10mg213.00€25mg319.00€50mg450.00€100mg605.00€200mg802.00€17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic Acid
CAS:Aspirin-enhanced COX-2 metabolite of DHA, activates Nrf2 and PPARγ, inhibits inflammation, with EC50 ~200 nM, effective at 5-25 μM.Formula:C22H30O3Color and Shape:SolidMolecular weight:342.479NHC-triphosphate tetrasodium
NHC-triphosphate tetrasodium, a metabolite of β-d-N4-Hydroxycytidine, acts as a viral polymerase substrate affecting HCV RNA replication.Formula:C9H12N3Na4O15P3Color and Shape:SolidMolecular weight:587.08Leriglitazone
CAS:Leriglitazone is a brain-permeable PPARγ agonist (EC50=9 μM) and mitochondrial modulator with neuroprotective and anti-inflammatory properties.Formula:C19H20N2O4SPurity:99.67%Color and Shape:SolidMolecular weight:372.44Ref: TM-T15736
1mg147.00€5mg356.00€1mL*10mM (DMSO)393.00€10mg572.00€25mg1,063.00€50mg1,459.00€100mg1,963.00€(R)-VX-984
CAS:(R)-VX-984 ((R)-M9831) is the (R)-enantiomer of VX-984. VX-984 is a potent inhibitor of DNA-PK.Formula:C23H21D2N7OPurity:98%Color and Shape:SolidMolecular weight:415.49ALKBH1-IN-1
ALKBH1-IN-1 (Compound 13h) is a selective ALKBH1 inhibitor with IC50 values of 0.026 μM in fluorescence polarization assays and 1.39 μM in enzyme activity assays. It can regulate the levels of DNA 6mA modifications and is useful for studying the functions of ALKBH1 and DNA 6mA.Formula:C16H11F3N4O4Molecular weight:380.07324Tet1
CAS:Tet1 is a peptide with the sequence HLNILSTLWKYRC. It specifically binds to the neuronal ganglioside receptor GT1b, which gives it the ability to target neurons. Tet1 is suitable for research related to drug delivery.Formula:C76H119N21O18SColor and Shape:SolidMolecular weight:1646.95PDPH Crosslinker
CAS:PDPH crosslinker(SPDP Hydrazide) is a lytic heterobisfunctional protein crosslinker.Formula:C8H11N3OS2Color and Shape:SolidMolecular weight:229.32
