DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
Subcategories of "DNA Damage/DNA Repair"
- ATM/ATR(71 products)
- DNA Alkylation(11 products)
- DNA Methyltransferase(421 products)
- DNA gyrase(11 products)
- DNA-PK(51 products)
- MTH1(1 products)
- Nucleoside Antimetabolite/Analog(1,388 products)
- Reverse Transcriptase(43 products)
- Sirtuin(88 products)
- Telomerase(33 products)
- Topoisomerase(136 products)
Show 3 more subcategories
Found 957 products of "DNA Damage/DNA Repair"
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Tallimustine HCl
CAS:<p>Tallimustine HCl, an AT-specific alkylating agent, treats leukemia in immunodeficiency mouse models.</p>Formula:C32H39Cl3N10O4Purity:98.52%Color and Shape:SoildMolecular weight:734.08Candesartan
CAS:<p>Candesartan (CV 11974) is an angiotensin II receptor blocker used widely in the therapy of hypertension and heart failure.</p>Formula:C24H20N6O3Purity:98.3% - 99.55%Color and Shape:Colorless Solid CrystallineMolecular weight:440.47Oxaquin TEA
<p>Oxaquin TEA (MCB-3837 TEA), a precursor compound to MCB3681, is a DNA topoisomerase inhibitor that can be used to study Clostridium difficile infections and</p>Formula:C37H48F2N5O11PPurity:99.79%Color and Shape:SolidMolecular weight:807.77MSDC-0602K
CAS:<p>MSDC-0602K, a Ps-TZD, targets PPARγ (IC50: 18.25 μM) and MPC, may help study fatty liver, lipid imbalance, inflammation, and insulin issues.</p>Formula:C19H16KNO5SPurity:99.42%Color and Shape:SolidMolecular weight:409.5Flumequine
CAS:<p>Flumequine (R-802) is a broad-spectrum antibiotic targeting DNA gyrase and topoisomerase IV in Gram-positive and Gram-negative bacteria.</p>Formula:C14H12FNO3Purity:98.92% - 99.4%Color and Shape:White Crystalline Powder SolidMolecular weight:261.25STL127705
CAS:<p>STL127705 inhibits Ku 70/80 protein & DNA-PKCS kinase, IC50s: 3.5 μM & 2.5 μM.</p>Formula:C22H20FN5O4Purity:99.53% - 99.81%Color and Shape:SolidMolecular weight:437.42Ciprofloxacin
CAS:<p>Ciprofloxacin (Bay-09867) mainly targets bacterial DNA Gyrase (IC50=0.22-0.31 µM) and topoisomerase IV (IC50=0.3-1.9 µM). antibiotic. High-Quality, Low-Cost!</p>Formula:C17H18FN3O3Purity:98.77% - 99.91%Color and Shape:White PowderMolecular weight:331.34Bendamustine hydrochloride
CAS:<p>Bendamustine hydrochloride (EP-3101) (IC50 of 50 μM) is an alkylating agent associated with DNA damage.</p>Formula:C16H21Cl2N3O2·HClPurity:97.71%Color and Shape:SolidMolecular weight:394.72Hydroxychloroquine sulfate
CAS:<p>Hydroxychloroquine sulfate (Acidum iopanoicum) inhibits plasmodial heme polymerase.</p>Formula:C18H26ClN3O·H2SO4Purity:98.92% - 99.88%Color and Shape:Odorless SolidMolecular weight:433.95Thio-TEPA
CAS:<p>Thio-TEPA (Tiofosyl) is a polyfunctional, organophosphorus alkylating agent with antineoplastic activity.</p>Formula:C6H12N3PSPurity:98.45% - 99.07%Color and Shape:White Crystals Or PowderMolecular weight:189.22NTP42
CAS:<p>NTP42 is an antagonist of thromboxane A2 (TXA2) receptor(IC50 of 3.278 nM)</p>Formula:C25H23F2N3O5SPurity:97.55%Color and Shape:SolidMolecular weight:515.53Gemfibrozil
CAS:<p>Gemfibrozil, a fibric acid derivative, stimulates PPARalpha, boosts fatty acid oxidation, LPL, lowers VLDL-C, apoC-III, and raises HDL-C.</p>Formula:C15H22O3Purity:99.53% - 99.88%Color and Shape:Crystals From Hexane SolidMolecular weight:250.33Altretamine
CAS:<p>Altretamine (ENT-50852) is an alkylating agent with antineoplastic activity.</p>Formula:C9H18N6Purity:99.54%Color and Shape:Less Crystalline Solid Insoluble In Water (Ntp 1992) Physical Description Colorless Crystalline Solid Insoluble In Water (Ntp 1992)Molecular weight:210.28Chlorambucil
CAS:<p>Chlorambucil (CB-1348) is an orally-active antineoplastic aromatic nitrogen mustard.</p>Formula:C14H19Cl2NO2Purity:97.37% - 98.45%Color and Shape:Off-White Slightly Granular Powder Melting Point 65-69°CMolecular weight:304.21Ciprofloxacin monohydrochloride
CAS:<p>Ciprofloxacin monohydrochloride (Bay-09867 hydrochloride) is a broad-spectrum antimicrobial carboxyfluoroquinoline.</p>Formula:C17H18FN3O3·HClPurity:99.5% - >99.99%Color and Shape:White Or Light Yellow Crystalline PowderMolecular weight:367.80G150
CAS:<p>G150 suppresses DSDNA-induced interferon; IC50: 10.2 nM. It's a potent, selective H-CGAS inhibitor.</p>Formula:C18H16Cl2N4O2Purity:97.75%Color and Shape:SolidMolecular weight:391.25BRD 4354
CAS:<p>BRD 4354 is an inhibitor of HDAC5 and HDAC9. For HDAC5 and HDAC9, the IC50s values are 0.85 and 1.88 μM, respectively.</p>Formula:C21H23ClN4OPurity:99.86%Color and Shape:SolidMolecular weight:382.89Levetiracetam
CAS:<p>Levetiracetam (SIB-S1) is a relatively unique anticonvulsant that is typically used in combination with other antiepileptic medications for partial onset</p>Formula:C8H14N2O2Purity:99.67% - 99.86%Color and Shape:White Crystalline PowderMolecular weight:170.215-Azacytidine
CAS:<p>5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity.</p>Formula:C8H12N4O5Purity:99.31% - 99.79%Color and Shape:Crystals From Methanol Physical Description White Crystalline Powder (Ntp 1992)Molecular weight:244.2LTURM34
CAS:<p>LTURM34 is an inhibitor of DNA-PK with IC50 of 34 nM.</p>Formula:C24H18N2O3SPurity:99.34%Color and Shape:SolidMolecular weight:414.48Clofibric acid
CAS:<p>Clofibric acid (Chlorofibrinic acid) is an antilipemic agent that is the biologically active metabolite of CLOFIBRATE.</p>Formula:C10H11ClO3Purity:99.47% - 99.8%Color and Shape:Pale Yellow SolidMolecular weight:214.65Sparfloxacin
CAS:<p>Sparfloxacin (CI-978) is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase, thereby inhibiting DNA replication and transcription.</p>Formula:C19H22F2N4O3Purity:99.67% - >99.99%Color and Shape:Light Yellow PowderMolecular weight:392.40Fleroxacin
CAS:<p>Fleroxacin (RO 23-6240) is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase.</p>Formula:C17H18F3N3O3Purity:99.58% - 99.79%Color and Shape:White Needle-Like CrystalsMolecular weight:369.34AES-135
CAS:<p>AES-135 is a potent HDAC inhibitor, inhibits HDAC3, HDAC6, HDAC11 (IC50s: 654, 190, and 636 nM) with anti-tumor activity.</p>Formula:C33H29F6N3O5SPurity:97.72%Color and Shape:SolidMolecular weight:693.66Ofloxacin
CAS:<p>Ofloxacin (Oxaldin) is a fluoroquinolone antibacterial antibiotic.</p>Formula:C18H20FN3O4Purity:99.33% - 99.87%Color and Shape:Off-White SolidMolecular weight:361.371-Naphthohydroxamic acid
CAS:<p>1-Naphthohydroxamic acid (Compound 2) is a potent and selective HDAC8 inhibitor with an IC50 of 14 μM, and it is more selectively for HDAC8 than class I HDAC1</p>Formula:C11H9NO2Purity:99.19%Color and Shape:SolidMolecular weight:187.19TRF1-TIN2 interaction-IN-1
<p>TRF1-TIN2 interaction-IN-1 (Compound 40) is an inhibitor of the TRF1-TIN2 interaction. It binds to the TRFH domain of TRF1 (KD= 29 μM) and competitively inhibits the binding of the TIN2 peptide (IC50= 67 μM). By occupying a hotspot at the TRF1-TIN2 interface, TRF1-TIN2 interaction-IN-1 disrupts the interaction between TRF1 and TIN2. This compound can remove TRF1 from the shelterin complex, making it useful for research on shelterin-related cancers.</p>Formula:C19H18O6SColor and Shape:SolidMolecular weight:374.41(R)-VX-984
CAS:<p>(R)-VX-984 ((R)-M9831) is the (R)-enantiomer of VX-984. VX-984 is a potent inhibitor of DNA-PK.</p>Formula:C23H21D2N7OPurity:98%Color and Shape:SolidMolecular weight:415.49PDPH Crosslinker
CAS:<p>PDPH crosslinker(SPDP Hydrazide) is a lytic heterobisfunctional protein crosslinker.</p>Formula:C8H11N3OS2Color and Shape:SolidMolecular weight:229.32DB1255 2TFA
<p>DB1255 2TFA is an ERG/DNA binding inhibitor with an unusual and potent monomer binding pattern at the minor groove site for the study of genetic disorders.</p>Formula:C26H20F6N4O4S2Purity:98.32%Color and Shape:SolidMolecular weight:630.58CAY10599
CAS:<p>CAY10599 has a wide range of applications in life science related research.</p>Formula:C38H41NO5Color and Shape:SolidMolecular weight:591.748NHC-triphosphate tetrasodium
<p>NHC-triphosphate tetrasodium, a metabolite of β-d-N4-Hydroxycytidine, acts as a viral polymerase substrate affecting HCV RNA replication.</p>Formula:C9H12N3Na4O15P3Color and Shape:SolidMolecular weight:587.08Amorfrutin B
CAS:<p>Amorfrutin B is a useful organic compound for research related to life sciences. The catalog number is T124211 and the CAS number is 78916-42-4.</p>Formula:C26H32O4Color and Shape:SolidMolecular weight:408.538Tibesaikosaponin V
CAS:<p>TKV, a triterpene diglycoside from Bupleurum chinense, curbs lipid build-up and fat content in adipocytes without harm and hinders fat cell differentiation.</p>Formula:C42H68O15Color and Shape:SolidMolecular weight:812.98GW 1929 hydrochloride
CAS:<p>Oral PPARγ agonist with pEC50 of 8.05; low affinity for PPARα, PPARδ. Reduces blood glucose, fatty acids, triglycerides in vivo.</p>Formula:C30H30ClN3O4Color and Shape:SolidMolecular weight:532.04SMPB Crosslinker
CAS:<p>SMPB crosslinker reacts with sulfhydryl/amino groups, has a longer chain than MBS, and a non-cleavable spacer arm.</p>Formula:C18H16N2O6Purity:98%Color and Shape:SolidMolecular weight:356.33Anti-obesity agent 1
<p>Compound 4 (Anti-obesity agent 1) demonstrates potential for enhanced lipolysis, highlighting its anti-obesity characteristics.</p>Formula:C21H22N2O6Color and Shape:SolidMolecular weight:398.409ACT-387042
CAS:<p>ACT-387042 is a Bacterial Topoisomerase Inhibitor, it has broad-spectrum activity against Gram-positive and Gram-negative bacteria.</p>Formula:C23H26FN5O4SColor and Shape:SolidMolecular weight:487.55CUDA disodium
<p>CUDA disodium is an effective, soluble epoxide hydrolase (sEH) inhibitor, with IC50 values of 11.1 nM for murine sEH and 112 nM for human sEH. It selectively enhances the activity of peroxisome proliferator-activated receptor PPARalpha. CUDA disodium may be valuable for cardiovascular disease research.</p>Color and Shape:Odour SolidGemfibrozil 1-O-β-glucuronide
CAS:<p>Gemfibrozil 1-O-β-Glucuronide, a metabolite of Gemfibrozil , is a potent and competitive P450 (CYP) isoform CYP2C8 inhibitor with an IC50 of 4.07 μM.</p>Formula:C21H30O9Purity:98%Color and Shape:SolidMolecular weight:426.46DNA Damage & Repair Compound Library
<p>A unique collection of xnum DNA Damage &amp; Repair related compounds for high throughput screening (HTS) and high content screening (HCS);</p>Color and Shape:Odour SolidWAY-323061
CAS:<p>WAY-323061 is a SIRT2 inhibitor.</p>Formula:C25H21N5O2SPurity:99.33%Color and Shape:SolidMolecular weight:455.53NHC-diphosphate triammonium
<p>NHC-triphosphate triammonium is a phosphorylated metabolite of NHC, incorporated into HCV RNA by viral polymerase.</p>Color and Shape:SolidTAK1 inhibitor
CAS:<p>TAK1 inhibitor is an inhibitor, which can inhibit MCF-7, A549, DU-145 and MDA MB-231, with IC50 of 0.021, 0.14, 0.064 and 0.19, respectively.</p>Formula:C22H19ClN6O2SPurity:98%Color and Shape:SoildMolecular weight:466.94MS9024
<p>MS9024 is a degrader of DNA methyltransferase 1 (DNMT1), facilitating its degradation in HCT116 cells via the ubiquitin-proteasome pathway, with a DC50 of 35 nM (DC50 values are 254 nM in MDA-MB-468 and 101 nM in H1299). Additionally, MS9024 inhibits DNMT1 with an IC50 of 0.43 μM.</p>Color and Shape:Odour SolidGSK3735967
CAS:<p>GSK3735967: DNMT1 inhibitor, IC50 40 nM, dicyanopyridine core, binds hemimethylated CpG, interacts with H4K20me3.</p>Formula:C25H31N7OSColor and Shape:SolidMolecular weight:477.62Ciprofibrate impurity A
CAS:<p>Ciprofibrate impurity A is an impurity of Ciprofibrate. Ciprofibrate is a PPARα agonist[1].</p>Formula:C12H14O3Color and Shape:SolidMolecular weight:206.241Murrayanol
<p>Murrayanol is a useful organic compound for research related to life sciences and the catalog number is T125851.</p>Formula:C24H29NO2Color and Shape:SolidMolecular weight:363.501Elomotecan
CAS:<p>Elomotecan (BN 80927 free base) is a potent inhibitor of topoisomerases I and II.Cost-effective and quality-assured.</p>Formula:C29H32ClN3O4Color and Shape:SolidMolecular weight:522.04Colibactin 742
CAS:<p>Colibactin 742, a stable derivative of colibactin, efficiently induces DNA interstrand cross-links, activates the Fanconi Anemia DNA repair pathway, and leads</p>Formula:C37H42N8O5S2Color and Shape:SolidMolecular weight:742.91
