DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
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Subcategories of "DNA Damage/DNA Repair"
ATM/ATR
DNA Alkylation
DNA Methyltransferase
DNA gyrase
DNA-PK
MTH1
Nucleoside Antimetabolite/Analog
Reverse Transcriptase
Sirtuin
Telomerase
Topoisomerase
Show 3 more subcategories
Products of "DNA Damage/DNA Repair"
azd1390
CAS:2089288-03-7
AZD1390: Potent ATM inhibitor (IC50: 0.78 nM), >10,000-fold selectivity vs. PIKK enzymes.
Formula:
C27H32FN5O2
Purity:
97.47% - 99.38%
Color and Shape:
Solid
Molecular weight:
477.57
Ref: TM-T5175
| 1mg | 86.00 € | ||
| 2mg | 105.00 € | ||
| 5mg | 157.00 € | ||
| 10mg | 224.00 € | ||
| 25mg | 453.00 € | ||
| 50mg | 578.00 € | ||
| 100mg | 745.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
RGFP966
CAS:1357389-11-7
RGFP966 is an HDAC3 inhibitor (IC50: 0.08 μM) and does not affect other HDACs at …
Formula:
C21H19FN4O
Purity:
99.2% - 99.77%
Color and Shape:
Solid
Molecular weight:
362.4
Ref: TM-T1762
| 1mg | 36.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 185.00 € | ||
| 50mg | 291.00 € | ||
| 100mg | 477.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
RG2833
CAS:1215493-56-3
RG2833 (RGFP109) (RGFP109), a brain-penetrant HDAC inhibitor, is with IC50 of 60 nM and 50 …
Formula:
C20H25N3O2
Purity:
98.93% - 99.13%
Color and Shape:
Solid
Molecular weight:
339.43
Ref: TM-T6639
| 5mg | 35.00 € | ||
| 10mg | 55.00 € | ||
| 25mg | 66.00 € | ||
| 50mg | 78.00 € | ||
| 100mg | 113.00 € | ||
| 200mg | 182.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
3,4-Dicaffeoylquinic acid
CAS:14534-61-3
3,4-Dicaffeoylquinic acid (Isochlorogenic acid B) has antioxidant activity.
Formula:
C25H24O12
Purity:
96.22% - 99.52%
Color and Shape:
Solid
Molecular weight:
516.45
Ref: TM-T6S1525
| 1mg | 42.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 104.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 247.00 € | ||
| 100mg | 367.00 € | ||
| 500mg | 871.00 € | ||
| 1mL*10mM (DMSO) | 109.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Seclidemstat
CAS:1423715-37-0
Seclidemstat (SP-2577) is an effective LSD1 inhibitor, with a mean IC50 of 127 nM.
Formula:
C20H23ClN4O4S
Purity:
98.03% - 98.68%
Color and Shape:
Solid
Molecular weight:
450.94
Ref: TM-T4527
| 5mg | 48.00 € | ||
| 10mg | 72.00 € | ||
| 25mg | 119.00 € | ||
| 50mg | 184.00 € | ||
| 100mg | 349.00 € | ||
| 200mg | 519.00 € | ||
| 500mg | 837.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Veliparib dihydrochloride
CAS:912445-05-7
Veliparib dihydrochloride (ABT-888 dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Ki of …
Formula:
C13H18Cl2N4O
Purity:
97.09% - 98%
Color and Shape:
Solid
Molecular weight:
317.21
Ref: TM-T2105
| 5mg | 35.00 € | ||
| 10mg | 47.00 € | ||
| 25mg | 76.00 € | ||
| 50mg | 113.00 € | ||
| 100mg | 176.00 € | ||
| 200mg | 287.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Prexasertib dihydrochloride
CAS:1234015-54-3
Prexasertib dihydrochloride (LY2606368) inhibits CHK1 (Ki: 0.9 nM); IC50: CHK2 8 nM, RSK 9 nM.
Formula:
C18H21Cl2N7O2
Purity:
97.5% - 99.82%
Color and Shape:
Solid
Molecular weight:
438.31
Ref: TM-T4327
| 1mg | 45.00 € | ||
| 2mg | 58.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 142.00 € | ||
| 25mg | 269.00 € | ||
| 50mg | 418.00 € | ||
| 100mg | 616.00 € | ||
| 500mg | 1,299.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Veliparib
CAS:912444-00-9
Veliparib (ABT-888) (ABT-888) is an orally bioavailable inhibitor of PARP (Kis: 5.2/2.9 nM for PARP1/2). …
Formula:
C13H16N4O
Purity:
98.66% - 99%
Color and Shape:
Solid
Molecular weight:
244.29
Ref: TM-T2591
| 5mg | 56.00 € | ||
| 10mg | 80.00 € | ||
| 25mg | 124.00 € | ||
| 50mg | 202.00 € | ||
| 100mg | 325.00 € | ||
| 200mg | 528.00 € | ||
| 500mg | 837.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
NU1025
CAS:90417-38-2
NU1025 (NSC-696807) is a potent PARP inhibitor with IC50 of 400 nM.
Formula:
C9H8N2O2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
176.17
Ref: TM-T6912
| 5mg | 45.00 € | ||
| 10mg | 67.00 € | ||
| 25mg | 113.00 € | ||
| 50mg | 184.00 € | ||
| 100mg | 290.00 € | ||
| 200mg | 419.00 € | ||
| 1mL*10mM (DMSO) | 45.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Deoxycytidine triphosphate trisodium salt
CAS:109909-44-6
Deoxycytidine triphosphate trisodium salt (2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI) contributes to antibiotic lethality in stationary-phase mycobacteria.
Formula:
C9H13N3Na3O13P3
Purity:
99.80%
Color and Shape:
Solid
Molecular weight:
533.1
Ref: TM-T7518
| 10mg | 66.00 € | ||
| 50mg | 131.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
DOPE
CAS:4004-05-1
DOPE, a neutral lipid, boosts cationic liposome efficiency in non-viral gene delivery.
Formula:
C41H78NO8P
Purity:
97.23%
Color and Shape:
Lyophilized Powder
Molecular weight:
744.03
Ref: TM-T19080
| 100mg | 94.00 € | ||
| 250mg | 183.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Dihydrocoumarin
CAS:119-84-6
Dihydrocoumarin, in Melilotus, inhibits yeast Sir2p, human SIRT1 (IC50: 208μM), and SIRT2 (IC50: 295μM).
Formula:
C9H8O2
Purity:
99.19%
Color and Shape:
Leaflets Room Temperature (Ntp 1992)
Molecular weight:
148.16
Ref: TM-T2S0300
| 10g | 34.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
L67
CAS:325970-71-6
L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I …
Formula:
C16H14Br2N4O4
Purity:
98.34% - 99.56%
Color and Shape:
Solid
Molecular weight:
486.11
Ref: TM-T3103
| 10mg | 49.00 € | ||
| 25mg | 72.00 € | ||
| 50mg | 92.00 € | ||
| 100mg | 136.00 € | ||
| 200mg | 182.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
AK-7
CAS:420831-40-9
AK-7 is a brain-permeable SIRT2 inhibitor and to characterize its cholesterol-reducing properties in neuronal models …
Formula:
C19H21BrN2O3S
Purity:
98.43%
Color and Shape:
Solid
Molecular weight:
437.35
Ref: TM-T5490
| 1mg | 36.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 103.00 € | ||
| 25mg | 183.00 € | ||
| 50mg | 323.00 € | ||
| 100mg | 529.00 € | ||
| 1mL*10mM (DMSO) | 94.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
PI-103
CAS:371935-74-9
PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for …
Formula:
C19H16N4O3
Purity:
96.59% - 99.3%
Color and Shape:
Solid
Molecular weight:
348.36
Ref: TM-T6143
| 5mg | 36.00 € | ||
| 10mg | 44.00 € | ||
| 25mg | 81.00 € | ||
| 50mg | 118.00 € | ||
| 100mg | 210.00 € | ||
| 200mg | 320.00 € | ||
| 1mL*10mM (DMSO) | 37.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
AK-1
CAS:330461-64-8
AK-1: SIRT2 inhibitor, IC50 12.5 μM, hinders Alzheimer's neurodegeneration, arrests colon cancer cell cycle.
Formula:
C19H21N3O5S
Purity:
98.32% - 99.01%
Color and Shape:
Solid
Molecular weight:
403.45
Ref: TM-T5618
| 5mg | 35.00 € | ||
| 10mg | 49.00 € | ||
| 25mg | 93.00 € | ||
| 50mg | 159.00 € | ||
| 100mg | 231.00 € | ||
| 200mg | 342.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
4'-bromo-Resveratrol
CAS:1224713-90-9
4'-bromo-Resveratrolis a potent inhibitor of the deacetylases sirtuin 1 (SIRT1) and 3 (SIRT3)
Formula:
C14H11BrO2
Purity:
99.4%
Color and Shape:
Solid
Molecular weight:
291.14
Ref: TM-T21679
| 5mg | 48.00 € | ||
| 10mg | 70.00 € | ||
| 25mg | 131.00 € | ||
| 50mg | 206.00 € | ||
| 100mg | 331.00 € | ||
| 200mg | 459.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
E1231
CAS:1031195-19-3
E1231 is an activator of SIRT1 . E1231 protects from experimental atherosclerosis and lowers plasma …
Formula:
C21H21N3O3
Purity:
98.45%
Color and Shape:
Solid
Molecular weight:
363.41
Ref: TM-T9106
| 1mg | 35.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 102.00 € | ||
| 25mg | 202.00 € | ||
| 50mg | 322.00 € | ||
| 100mg | 464.00 € | ||
| 500mg | 917.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
4'-Methoxychalcone
CAS:959-23-9
4'-Methoxychalcone with a variety of pharmacological activities, such as anti-tumor and anti-inflammatory activities.
Formula:
C16H14O2
Purity:
98.93%
Color and Shape:
Solid
Molecular weight:
238.28
Ref: TM-T7443
| 50mg | 50.00 € | ||
| 100mg | 72.00 € | ||
| 500mg | 161.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
XAV-939
CAS:284028-89-3
XAV-939 (NVP-XAV939) shows the selective inhibition against Wnt/β-catenin-mediated transcription by tankyrase1/2 inhibition (IC50: 11/4 nM …
Formula:
C14H11F3N2OS
Purity:
97.47% - 99.04%
Color and Shape:
Solid
Molecular weight:
312.31
Ref: TM-T1878
| 5mg | 57.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 113.00 € | ||
| 50mg | 172.00 € | ||
| 100mg | 262.00 € | ||
| 200mg | 460.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
