DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
Subcategories of "DNA Damage/DNA Repair"
- ATM/ATR(72 products)
- DNA Alkylation(18 products)
- DNA Methyltransferase(459 products)
- DNA gyrase(6 products)
- DNA-PK(49 products)
- MTH1(1 products)
- Nucleoside Antimetabolite/Analog(1,421 products)
- Reverse Transcriptase(42 products)
- Sirtuin(86 products)
- Telomerase(34 products)
- Topoisomerase(130 products)
Show 3 more subcategories
Found 922 products of "DNA Damage/DNA Repair"
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Corydamine
Corydamine is a useful organic compound for research related to life sciences and the catalog number is T124768.Formula:C20H18N2O4Color and Shape:SolidMolecular weight:350.374NHC-triphosphate tetrasodium
NHC-triphosphate tetrasodium, a metabolite of β-d-N4-Hydroxycytidine, acts as a viral polymerase substrate affecting HCV RNA replication.Formula:C9H12N3Na4O15P3Color and Shape:SolidMolecular weight:587.08Antitumor agent-63
CAS:Compound 40, a non-toxic 20(S)-O-CPT glycoconjugate, is stable, with low Topo I inhibition.Formula:C38H46N4O18Color and Shape:SolidMolecular weight:846.79PDPH Crosslinker
CAS:PDPH crosslinker(SPDP Hydrazide) is a lytic heterobisfunctional protein crosslinker.Formula:C8H11N3OS2Color and Shape:SolidMolecular weight:229.32SCR7
CAS:SCR7, a specific DNA Ligase IV inhibitor, blocks nonhomologous end-joining (NHEJ).Formula:C18H14N4OSPurity:98%Color and Shape:SolidMolecular weight:334.4PARP10-IN-3
CAS:PARP10-IN-3: selective inhibitor for mono-ADP-ribotransferase PARP10 (IC50: 480nM), also affects PARP2 and PARP15 (IC50: 1.7μM).
Formula:C14H12N2O3Purity:99.41%Color and Shape:SoildMolecular weight:256.269-Nitrooleate
CAS:Nitrated fatty acids like nitrolinoleate and nitrooleate serve as PPARγ ligands and release NO; found in plasma, they aid adipocyte differentiation.
Formula:C18H33NO4Color and Shape:SolidMolecular weight:327.4651-O-Hexadecyl-Rac-Glycerol
CAS:1-O-Hexadecyl-Rac-Glycerol (1-O-Hexadecylglycerol) is a marine derived natural products found in Tritoniella belli.Formula:C19H40O3Purity:99.38% - 99.94%Color and Shape:SolidMolecular weight:316.52(±)4(5)-DiHDPA lactone
CAS:(±)5(6)-DiHET lactone is a 1,5 cyclic ester derived from (±)5(6)-DiHET , which, in turn, is a potential derivative of epoxidation of arachidonic acid at the α-5Formula:C22H32O3Color and Shape:SolidMolecular weight:344.495Macrocalin B
CAS:Macrocalin B is a diterpenoid against tumor cell proliferation and telomerase activity.Formula:C20H26O6Color and Shape:SolidMolecular weight:362.42Sulotroban
CAS:sulotroban is a TXA2 receptor antagonist that acts synergistically with iloprost to inhibit TXA2-dependent platelet activation.Formula:C16H17NO5SPurity:98.86% - 99.98%Color and Shape:SolidMolecular weight:335.37Saroglitazar Magnesium
CAS:Saroglitazar Magnesium: a PPAR agonist, strong on PPARα (EC50 0.65pM), moderate on PPARγ (EC50 3nM).Formula:C50H56MgN2O8S2Purity:99.40%Color and Shape:SolidMolecular weight:901.43Ref: TM-T12834
1mg54.00€5mg126.00€10mg178.00€25mg309.00€50mg416.00€100mg532.00€1mL*10mM (DMSO)178.00€17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic Acid
CAS:Aspirin-enhanced COX-2 metabolite of DHA, activates Nrf2 and PPARγ, inhibits inflammation, with EC50 ~200 nM, effective at 5-25 μM.Formula:C22H30O3Color and Shape:SolidMolecular weight:342.479Ketopioglitazone
CAS:Ketopioglitazone is an active metabolite of pioglitazone.Formula:C19H18N2O4SColor and Shape:SolidMolecular weight:370.42NHC-diphosphate
CAS:NHC-diphosphate, a phosphorylated β-d-N4-Hydroxycytidine metabolite, is a potent antiviral against VEEV, CHIKV, and HCV.Formula:C9H15N3O12P2Color and Shape:SolidMolecular weight:419.18TAK1 inhibitor
CAS:TAK1 inhibitor is an inhibitor, which can inhibit MCF-7, A549, DU-145 and MDA MB-231, with IC50 of 0.021, 0.14, 0.064 and 0.19, respectively.
Formula:C22H19ClN6O2SPurity:98%Color and Shape:SoildMolecular weight:466.94PNU-142586
CAS:PNU-142586 is a bio-active chemical.Formula:C16H20FN3O6Color and Shape:SolidMolecular weight:369.34Melphalan
CAS:Melphalan is an orally bioavailable DNA alkylating agent exhibiting antitumour activity, commonly employed in cancer chemotherapy.Formula:C13H18Cl2N2O2Color and Shape:SolidMolecular weight:305.21E0924G
CAS:E0924G is an orally active PPARδ agonist with an EC50 of 2.82 μM. It enhances the upregulation of osteoprotegerin (OPG) expression, with an EC50 of 0.29 μM. E0924G reduces RANKL-induced osteoclast differentiation and inhibits F-actin ring formation in RAW264.7 macrophages. Additionally, E0924G modulates bone density and bone loss in models of ovariectomy (OVX) and age-related osteoporosis.Formula:C12H12N2O3Color and Shape:SolidMolecular weight:232.24AuM1Phe
AuM1Phe, an N-heterocyclic carbene (NHC) metal complex, inhibits both human topoisomerase I activity and actin polymerization.Purity:98%Color and Shape:Odour Solid
