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DNA Methyltransferase

DNA Methyltransferase

DNA methyltransferases (DNMTs) are enzymes that catalyze the addition of methyl groups to cytosine residues in DNA, leading to gene silencing. Aberrant DNA methylation is associated with various diseases, including cancer. DNMT inhibitors block the activity of these enzymes, leading to the reactivation of silenced genes and induction of apoptosis in cancer cells. DNMT inhibitors are widely used in epigenetic research and cancer therapy. At CymitQuimica, we provide a range of high-quality DNMT inhibitors to support your research in epigenetics, DNA methylation, and cancer biology.

Found 422 products of "DNA Methyltransferase"

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  • Tazemetostat
    Targetmol
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    Tazemetostat

    CAS:
    <p>Tazemetostat (EPZ6438): Oral EZH2 inhibitor, blocks histone H3K27 methylation, potential cancer therapy.</p>
    Formula:C34H44N4O4
    Purity:98.24% - ≥95%
    Color and Shape:Solid
    Molecular weight:572.74

    Ref: TM-T1788

  • MS049
    Targetmol
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    MS049

    CAS:
    <p>MS 049 is a potent, selective, and cell-active dual inhibitor of PRMT4 and PRMT6 with IC 50 of 34 nM and 43 nM, respectively.</p>
    Formula:C15H24N2O
    Purity:98.91%
    Color and Shape:Solid
    Molecular weight:248.36

    Ref: TM-T4378

  • EPZ004777
    Targetmol
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    EPZ004777

    CAS:
    <p>EPZ004777 is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.</p>
    Formula:C28H41N7O4
    Purity:98.99% - 99.32%
    Color and Shape:Solid
    Molecular weight:539.67

    Ref: TM-T3081

  • SGC707
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    SGC707

    CAS:
    <p>SGC707 is a potent, selective, and cell-active allosteric inhibitor of PRMT3.</p>
    Formula:C16H18N4O2
    Purity:98.45% - 99.79%
    Color and Shape:Solid
    Molecular weight:298.34

    Ref: TM-T3084

  • TP-064
    Targetmol
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    TP-064

    CAS:
    <p>TP-064: Potent, selective PRMT4 inhibitor, IC50 &lt; 10nM for H3 methylation, 100x selectivity, blocks MED12 methylation at 43nM.</p>
    Formula:C28H34N4O2
    Purity:97.85%
    Color and Shape:Solid
    Molecular weight:458.6

    Ref: TM-T28996

  • UNC1215
    Targetmol
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    UNC1215

    CAS:
    <p>UNC1215, a potent MBT antagonist, targets L3MBTL3 with high selectivity (IC50: 40 nM, Kd: 120 nM, 50x versus MBT family).</p>
    Formula:C32H43N5O2
    Purity:98% - 99.04%
    Color and Shape:Solid
    Molecular weight:529.72

    Ref: TM-T2379

  • MRTX9768
    Targetmol
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    MRTX9768

    CAS:
    <p>MRTX-9768 is a synthetic lethal-based inhibitor designed to bind the PRMT5-MTA complex and selectively target MTAP/CDKN2A-deleted tumors.</p>
    Formula:C24H17FN6O
    Purity:97.02%
    Color and Shape:Solid
    Molecular weight:424.43

    Ref: TM-T9575

  • EED226
    Targetmol
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    EED226

    CAS:
    <p>EED226 is a potent, selective, and orally bioavailable embryonic ectoderm development (EED) inhibitor with an IC50 of 22 nM.</p>
    Formula:C17H15N5O3S
    Purity:98.14% - 99.33%
    Color and Shape:Solid
    Molecular weight:369.4

    Ref: TM-T3458

  • AMI-1
    Targetmol
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    AMI-1

    CAS:
    <p>AMI-1 is an effective and selective Histone Methyltransferase (HMT) inhibitor (IC50: 3.0/8.8 μM, for yeast Hmt1p, and human PRMT1).</p>
    Formula:C21H14N2Na2O9S2
    Purity:97.53% - 99.9%
    Color and Shape:Drypowder
    Molecular weight:548.45

    Ref: TM-T2352

  • γ-Oryzanol
    Targetmol
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    γ-Oryzanol

    CAS:
    <p>γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the</p>
    Formula:C40H58O4
    Purity:mixture - mixture
    Color and Shape:White Or White Crystalline Powder Odourless
    Molecular weight:602.9

    Ref: TM-T3606

  • BIX-01294
    Targetmol
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    BIX-01294

    CAS:
    <p>BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).</p>
    Formula:C28H38N6O2
    Purity:98.58% - 99.64%
    Color and Shape:Solid
    Molecular weight:490.64

    Ref: TM-T7697

  • 3-deazaneplanocin A HCl
    Targetmol
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    3-deazaneplanocin A HCl

    CAS:
    <p>3-deazaneplanocin A HCl is both an S-adenosyl-l-homocysteine hydrolase inhibitor and an enhancer of zeste homolog 2(EZH2) inhibitor.</p>
    Formula:C12H15ClN4O3
    Purity:93.24% - 98.9%
    Color and Shape:Solid
    Molecular weight:298.73

    Ref: TM-T6360

  • CymitQuimica logo
    Targetmol
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    OTS186935 hydrochloride

    <p>OTS186935 HCl inhibits SUV39H2 (IC50 6.49 nM), curbs tumor growth in mice, and modulates γ-H2AX in cancer cells.</p>
    Formula:C25H27Cl2N5O2
    Color and Shape:Solid
    Molecular weight:522.31

    Ref: TM-T63654

  • AZ505
    Targetmol
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    AZ505

    CAS:
    <p>AZ505 is an effective and specific SMYD2 inhibitor (IC50: 0.12 μM).</p>
    Formula:C29H38Cl2N4O4
    Purity:98.18%
    Color and Shape:Solid
    Molecular weight:577.54

    Ref: TM-TQ0100

  • Tazemetostat hydrobromide
    Targetmol
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    Tazemetostat hydrobromide

    CAS:
    <p>Tazemetostat hydrobromide: potent, selective EZH2 inhibitor; blocks PRC2/wild-type EZH2 (Ki: 2.5 nM) &amp; EZH1 (IC50: 392 nM).</p>
    Formula:C34H45BrN4O4
    Purity:99.8%
    Color and Shape:Solid
    Molecular weight:653.65

    Ref: TM-T17002

  • WDR5-0103
    Targetmol
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    WDR5-0103

    CAS:
    <p>WDR5-0103 (WD-Repeat Protein 5-0103) is an effective and specific WD repeat-containing protein 5 (WDR5) antagonist (Kd: 450 nM).</p>
    Formula:C21H25N3O4
    Purity:98% - 99.61%
    Color and Shape:Solid
    Molecular weight:383.44

    Ref: TM-T3201

  • Succinic acid sodium
    Targetmol
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    Succinic acid sodium

    CAS:
    <p>Succinic acid sodium is an orally active anxiolytic.</p>
    Formula:C4H6O4·xNa
    Color and Shape:Solid

    Ref: TM-T64294

  • A-196
    Targetmol
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    A-196

    CAS:
    <p>A-196 is a potent and selective inhibitor of SUV420 h1 and SUV420 h2 with IC50 values of 0.025 and 0.144 μM, respectively; more than 100-fold selective over</p>
    Formula:C18H16Cl2N4
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:359.25

    Ref: TM-T4343

  • Piribedil
    Targetmol
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    Piribedil

    CAS:
    Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease.
    Formula:C16H18N4O2
    Purity:99.79% - 99.82%
    Color and Shape:Solid
    Molecular weight:298.34

    Ref: TM-T3278

  • C-7280948
    Targetmol
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    C-7280948

    CAS:
    <p>C-7280948 is a PRMT1 inhibitor.</p>
    Formula:C14H16N2O2S
    Purity:99.55% - ≥95%
    Color and Shape:Solid
    Molecular weight:276.35

    Ref: TM-T2097