Sirtuin
Sirtuins are a family of NAD+-dependent deacetylases that play a critical role in regulating cellular processes such as DNA repair, aging, metabolism, and stress resistance. Sirtuins influence DNA repair by deacetylating proteins involved in the repair pathways, thereby modulating their activity. Sirtuin inhibitors and activators are valuable tools in research on aging, cancer, and metabolic diseases, where the regulation of DNA repair and cellular longevity is of interest. At CymitQuimica, we offer a range of high-quality sirtuin modulators to support your research in DNA repair, cellular aging, and metabolic regulation.
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Nicotinamide riboside
CAS:1341-23-7
Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism …
Formula:
C11H15N2O5
Purity:
98.61% - 99.58%
Color and Shape:
Solid
Molecular weight:
255.25
Ref: TM-T13795
| 5mg | 54.00 € | ||
| 200mg | 223.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
SIRT-IN-2
CAS:1431411-66-3
SIRT-IN-2 is a potent SIRT1/2/3 inhibitor(IC50s of 4, 1, 7 μM, respectively).
Formula:
C15H21N5O3S2
Purity:
98.26%
Color and Shape:
Solid
Molecular weight:
383.49
Ref: TM-T12919
| 1mg | 105.00 € | ||
| 5mg | 225.00 € | ||
| 10mg | 360.00 € | ||
| 25mg | 613.00 € | ||
| 50mg | 838.00 € | ||
| 100mg | 1,144.00 € | ||
| 1mL*10mM (DMSO) | 247.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Resveratrol
CAS:501-36-0
Resveratrol (SRT 501) is a polyphenolic natural product, a plant antitoxin with antioxidant and chemopreventive …
Formula:
C14H12O3
Purity:
99.53% - 99.9%
Color and Shape:
Off-White To Tan Powder
Molecular weight:
228.24
Ref: TM-T1558
| 100mg | 43.00 € | ||
| 200mg | 54.00 € | ||
| 500mg | 82.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Z26395438
CAS:2803-63-6
Z26395438 is an inhibitor of Sirtuin-1 with IC50 of 1.6 μM.
Formula:
C17H15FN2O
Purity:
99.63%
Color and Shape:
Liquid
Molecular weight:
282.31
Ref: TM-T77653
| 1mg | 57.00 € | ||
| 2mg | 81.00 € | ||
| 5mg | 120.00 € | ||
| 10mg | 179.00 € | ||
| 25mg | 328.00 € | ||
| 50mg | 468.00 € | ||
| 100mg | 695.00 € | ||
| 500mg | 1,396.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
BML-278
CAS:120533-76-8
BML-278 is a SIRT1 activator with an EC150 of 1 μM.BML-278 increases H3K9 methylation and …
Formula:
C24H25NO4
Purity:
100%
Color and Shape:
Liquid
Molecular weight:
391.46
Ref: TM-T77697
| 5mg | 63.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 160.00 € | ||
| 50mg | 233.00 € | ||
| 100mg | 313.00 € | ||
| 500mg | 690.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Sirt1/2-IN-4
Sirt1/2-IN-4 (compound PS3) is a potent triple inhibitor of SIRT1, SIRT2, and SIRT3, exhibiting IC50 …
Formula:
C21H20N4O3S2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
440.54
Ref: TM-T79565
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
MIND4-19
CAS:129544-85-0
MIND4-19 is an inhibitor of SIRT2 with antitumor activity.
Formula:
C22H19N3OS
Purity:
99.9%
Color and Shape:
Liquid
Molecular weight:
373.47
Ref: TM-T9998
| 5mg | 46.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 130.00 € | ||
| 50mg | 205.00 € | ||
| 100mg | 328.00 € | ||
| 200mg | 463.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Et-29
CAS:2166487-23-4
Et-29 is a selective inhibitor of SIRT5 inhibitor with a Ki of 40 nM.
Formula:
C34H46N6O6S
Purity:
98.69%
Color and Shape:
Liquid
Molecular weight:
666.83
Ref: TM-T35347
| 1mg | 68.00 € | ||
| 5mg | 146.00 € | ||
| 10mg | 229.00 € | ||
| 25mg | 388.00 € | ||
| 50mg | 552.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
SIRT5 inhibitor 8
SIRT5 inhibitor 8 (compound 10) serves as a competitive inhibitor of sirtuin SIRT5, exhibiting an …
Formula:
C22H25ClN8O2S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
501
Ref: TM-T78856
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
WAY-323061
CAS:550301-63-8
WAY-323061 is a SIRT2 inhibitor.
Formula:
C25H21N5O2S
Purity:
99.33%
Color and Shape:
Liquid
Molecular weight:
455.53
Ref: TM-T77605
| 1mg | 183.00 € | ||
| 5mg | 402.00 € | ||
| 10mg | 595.00 € | ||
| 25mg | 922.00 € | ||
| 50mg | 1,271.00 € | ||
| 100mg | 1,710.00 € | ||
| 500mg | 3,438.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
SIRT1-IN-1
CAS:352554-02-0
SIRT1-IN-1 is a selective inhibitor of SIRT1 with an IC50 of 205 nM.Cost-effective and quality-assured.
Formula:
C14H16N2O
Purity:
99.31%
Color and Shape:
Liquid
Molecular weight:
228.29
Ref: TM-T9648
| 1mg | 96.00 € | ||
| 5mg | 200.00 € | ||
| 10mg | 308.00 € | ||
| 25mg | 527.00 € | ||
| 50mg | 738.00 € | ||
| 100mg | 994.00 € | ||
| 200mg | 1,340.00 € | ||
| 1mL*10mM (DMSO) | 205.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
SIRT3 activator 2
SIRT3 activator2 (compound 2a) acts as an activator of SIRT3. It is presumed to bind …
Formula:
C22H24N2O9S
Color and Shape:
Liquid
Molecular weight:
492.5
Ref: TM-T200160
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
Sirtuin modulator 2
CAS:667910-69-2
Sirtuin modulator 2 (N-(3-(imidazo[2,1-b]thiazol-6-yl)phenyl)-2-methoxybenzamide) exhibits antidiabetic, anti-inflammatory and antitumor activities.
Formula:
C19H15N3O2S
Purity:
99.47%
Color and Shape:
Liquid
Molecular weight:
349.41
Ref: TM-T9999
| 2mg | 41.00 € | ||
| 5mg | 62.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 282.00 € | ||
| 100mg | 402.00 € | ||
| 200mg | 569.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
HSP70/SIRT2-IN-1
HSP70/SIRT2-IN-1 (Compound 2a) serves as a dual inhibitor targeting both SIRT2 and HSP70, exhibiting an …
Purity:
98%
Ref: TM-T82168
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
MC3482
CAS:2922280-86-0
MC3482 is a specific inhibitor of sirtuin5 (SIRT5).
Formula:
C33H38N4O8
Purity:
98% - 99.48%
Color and Shape:
Soild
Molecular weight:
618.68
Ref: TM-T11962
| 1mg | 53.00 € | ||
| 2mg | 74.00 € | ||
| 5mg | 111.00 € | ||
| 10mg | 179.00 € | ||
| 25mg | 280.00 € | ||
| 50mg | 443.00 € | ||
| 100mg | 719.00 € | ||
| 500mg | 1,443.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
SIRT5 inhibitor 9
SIRT5 inhibitor 9 (compound 14), with an IC50 of 4.07 μM, is a competitive inhibitor …
Formula:
C24H29ClN8O4S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
561.06
Ref: TM-T78857
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
![Benzamide, 3-methoxy-N-(3-thiazolo[5,4-b]pyridin-2-ylphenyl)](https://static.cymitquimica.com/products/TM/thumb/T60001.jpg)
Benzamide, 3-methoxy-N-(3-thiazolo[5,4-b]pyridin-2-ylphenyl)
CAS:863589-52-0
3-Methoxybenzamide derivative modulates sirtuins; may boost cell lifespan and treat diseases.
Formula:
C20H15N3O2S
Purity:
99.02%
Color and Shape:
Liquid
Molecular weight:
361.42
Ref: TM-T60001
| 1mg | 54.00 € | ||
| 5mg | 107.00 € | ||
| 10mg | 155.00 € | ||
| 25mg | 250.00 € | ||
| 50mg | 369.00 € | ||
| 100mg | 525.00 € | ||
| 200mg | 712.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
SIRT1 activator 1
SIRT1 Activator 1 (Compound 3), a marine-derived xyloallenoide A derivative from the Xylaria sp.
Purity:
98%
Ref: TM-T81154
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
JGB1741
CAS:1256375-38-8
JGB1741, a SIRT1 inhibitor (IC50=15µM), modulates apoptosis markers and p53 acetylation in breast cancer research.
Formula:
C27H24N2O2S
Purity:
97.24%
Color and Shape:
Solid
Molecular weight:
440.56
Ref: TM-T22094
| 1mg | 60.00 € | ||
| 5mg | 169.00 € | ||
| 10mg | 282.00 € | ||
| 25mg | 497.00 € | ||
| 50mg | 720.00 € | ||
| 100mg | 1,006.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
MDL-800
CAS:2275619-53-7
MDL-800 is a SIRT6 modulator with antitumor activity for the study of hepatocellular carcinoma and …
Formula:
C21H16BrCl2FN2O6S2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
626.3
Ref: TM-T64529
| 1mg | 55.00 € | ||
| 5mg | 116.00 € | ||
| 10mg | 171.00 € | ||
| 25mg | 280.00 € | ||
| 50mg | 421.00 € | ||
| 100mg | 618.00 € | ||
| 500mg | 1,290.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
