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Glucocorticoid Receptor

Glucocorticoid Receptor

The glucocorticoid receptor (GR) is a nuclear hormone receptor that mediates the effects of glucocorticoids, a class of steroid hormones involved in the regulation of metabolism, immune response, and stress. Glucocorticoid receptor agonists and antagonists are widely used in the treatment of inflammatory and autoimmune diseases, as well as in cancer therapy. GR modulators are also important tools for studying the physiological and pathological roles of glucocorticoids. At CymitQuimica, we provide a wide range of high-quality glucocorticoid receptor modulators to support your research in endocrinology, immunology, and hormone regulation.

Found 158 products of "Glucocorticoid Receptor"

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  • Vamorolone

    CAS:
    Vamorolone (VBP15) is a steroid-like drug that treats muscular dystrophy with fewer side effects and inhibits NF-κB.
    Formula:C22H28O4
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:356.46
  • Fluocinonide

    CAS:
    <p>Fluocinonide (Topsyn) (Vanos) is an effective glucocorticoid steroid, utilized in the treatment as the skin disorders anti-inflammatory agent.</p>
    Formula:C26H32F2O7
    Purity:98.33% - 99.70%
    Color and Shape:Solid
    Molecular weight:494.52
  • (20S)-Protopanaxatriol

    CAS:
    <p>(20S)-Protopanaxatriol (g-PPT)(g-PPT), a metabolite of ginsenoside, could regulate endothelial cell functions through the estrogen receptor and glucocorticoid</p>
    Formula:C30H52O4
    Purity:95% - 99%
    Color and Shape:Solid
    Molecular weight:476.73
  • Finerenone

    CAS:
    Finerenone (BAY-948862) is a selective and orally nonsteroidal antagonist of the mineralocorticoid receptor (MR). Cost effective and quality assured.
    Formula:C21H22N4O3
    Purity:99.45% - 99.91%
    Color and Shape:Solid
    Molecular weight:378.42
  • Corticosterone

    CAS:
    Corticosterone (Kendall's compound B) is an adrenocortical steroid with salocorticoid and glucocorticoid activity that is orally active.
    Formula:C21H30O4
    Purity:98.44% - ≥95%
    Color and Shape:Solid
    Molecular weight:346.46
  • Fluorometholone Acetate

    CAS:
    <p>Fluorometholone Acetate (Oxylone acetate) is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.</p>
    Formula:C24H31FO5
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:418.50
  • Osilodrostat phosphate

    CAS:
    Osilodrostat phosphate is a potent oral 11β-hydroxylase inhibitor.
    Formula:C13H13FN3O4P
    Color and Shape:Solid
    Molecular weight:325.23
  • Osilodrostat

    CAS:
    Osilodrostat (LCI699) is a potent inhibitor of human 11β-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2).Cost-effective and quality-assured.
    Formula:C13H10FN3
    Purity:99.10% - 99.36%
    Color and Shape:Solid
    Molecular weight:227.24
  • Canrenoate potassium

    CAS:
    Canrenoate potassium (Soldactone) is a synthetic pregnadiene derivative with anti-aldosterone activity.
    Formula:C22H29KO4
    Purity:99.04% - 99.18%
    Color and Shape:Light Yellow To Tan Powder
    Molecular weight:396.56
  • Cortodoxone

    CAS:
    Cortodoxone (11-Desoxycortisol) is a glucocorticoid steroid hormone that is an intermediate in the biosynthesis of cortisol in the adrenal gland.
    Formula:C21H30O4
    Purity:99.26% - 99.87%
    Color and Shape:Solid
    Molecular weight:346.46
  • Ciclesonide

    CAS:
    Ciclesonide (Alvesco)(RPR251526) is a glucocorticoid used for the treatment of obstructive airway diseases.
    Formula:C32H44O7
    Purity:99.89% - >99.99%
    Color and Shape:Solid
    Molecular weight:540.69
  • AL 082D06

    CAS:
    AL 082D06 (D-06), a selective nonsteroidal glucocorticoid receptor (GR) antagonist (Ki: 210 nM), exhibits outstanding selectivity against AR, ER, MR and PR.
    Formula:C23H24ClN3O2
    Purity:99.05% - 99.06%
    Color and Shape:Solid
    Molecular weight:409.91
  • Halobetasol propionate

    CAS:
    <p>Halobetasol propionate (BMY-30056) is the salt of halobetasol, a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictor activities.</p>
    Formula:C25H31ClF2O5
    Purity:99.89%
    Color and Shape:Distributed As 0 05% Ointment
    Molecular weight:484.96
  • Velsecorat

    CAS:
    <p>Velsecorat (AZD7594) is an effective and selective nonsteroidal glucocorticoid receptor modulator (IC50: 0.9 nM).</p>
    Formula:C32H32F2N4O6
    Purity:99.35%
    Color and Shape:Solid
    Molecular weight:606.62
  • Mirodenafil dihydrochloride

    CAS:
    <p>Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.</p>
    Formula:C26H39Cl2N5O5S
    Purity:99.64% - 99.78%
    Color and Shape:Solid
    Molecular weight:604.59
  • Fludrocortisone acetate

    CAS:
    <p>Fludrocortisone acetate (9α-Fludrocortisone acetate) , a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, and</p>
    Formula:C23H31FO6
    Purity:96.92% - 98.03%
    Color and Shape:Crystalline Solid
    Molecular weight:422.49
  • Apararenone

    CAS:
    <p>Apararenone (MT-3995) is a receptor antagonist of mineralocorticoid receptor which can be used to treat non-alcoholic steatohepatitis and diabetic nephropathy.</p>
    Formula:C17H17FN2O4S
    Purity:99.79%
    Color and Shape:Solid
    Molecular weight:364.39
  • LY404039

    CAS:
    LY404039 (pomaglumetad) is an effective agonist of recombinant human mGlu2(Ki =149 nM)/mGlu3(Ki =92 nM).
    Formula:C7H9NO6S
    Purity:99% - 99.92%
    Color and Shape:Solid
    Molecular weight:235.22
  • Beclometasone dipropionate monohydrate

    CAS:
    <p>Beclometasone dipropionate monohydrate, precursor to oral glucocorticoid for inflammation and asthma research.</p>
    Formula:C28H39ClO8
    Color and Shape:Solid
    Molecular weight:539.06
  • Fluorometholone

    CAS:
    Fluorometholone (Fluoromethalone) is a corticosteroid, most often used after laser-based refractive surgery.
    Formula:C22H29FO4
    Purity:99% - 99.15%
    Color and Shape:Solid
    Molecular weight:376.46