Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(136 products)
- CXCR(148 products)
- Cell wall(5 products)
- IL Receptor(112 products)
- IκB/IKK(60 products)
- LTR(3 products)
- MALT(23 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(444 products)
- NOD(17 products)
- NOS(63 products)
- Nrf2(78 products)
- PGE Synthase(31 products)
- ROS(69 products)
- TGF-beta/Smad(58 products)
- TLR(66 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
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Found 3044 products of "Immunology and Inflammation"
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Lusvertikimab
CAS:<p>Lusvertikimab (OSE-127) is a humanized anti-IL7R antibody with anti-leukemic efficacy and can be used to study leukemia.</p>Purity:95% - 98.4% (SDS-PAGE); 99% (SEC-HPLC)Color and Shape:Liquid3,4-DAA
CAS:<p>3,4-DAA has anti-inflammatory activity and inhibits EOC20 cell-induced nitric oxide synthase (iNOS) induced by IFN-γ and lipopolysaccharide.</p>Formula:C18H17NO6Purity:98%Color and Shape:SolidMolecular weight:343.33(9α,13α,14α)-4-Hydroxy-3,7-dimethoxy-7,8-didehydromorphinan-6-one
CAS:(9α,13α,14α)-4-Hydroxy-3,7-dimethoxy-7,8-didehydromorphinan-6-one is a major mechanism of Sinomenine.Formula:C18H21NO4Purity:97.85%Color and Shape:SoildMolecular weight:315.36BMS-378806
CAS:BMS-378806 (BMS-806) selectively inhibits the binding of HIV-1 gp120 to the CD4 receptor with EC50 of 0.85-26.5 nM in virus.Formula:C22H22N4O4Purity:99.93%Color and Shape:SolidMolecular weight:406.43Avasopasem manganese
CAS:<p>Avasopasem manganese is a drug candidate of superoxide dismutase mimetic.</p>Formula:C21H35Cl2MnN5Purity:98%Color and Shape:SolidMolecular weight:483.38Kamebakaurin
CAS:<p>Kamebakaurin combats liver toxicity, cancer, inflammation, and neuroinflammation by blocking NF-κB, HIF-1α, and key signaling pathways.</p>Formula:C20H30O5Purity:98.05%Color and Shape:SolidMolecular weight:350.45FAPI-2
CAS:<p>FAPI-2 is a specific inhibitor of fibroblast-activated protein based on the radiotracer FAP labeling, and has anticancer activity.</p>Formula:C40H56N10O10Purity:98.76%Color and Shape:SolidMolecular weight:836.93TMV-IN-9
CAS:<p>TMV-IN-9 (compound A6) is an antiviral agent that exhibits exceptional inactivation effects against Tobacco Mosaic Virus (TMV), with an EC50 of 62.8 μg/mL. It demonstrates strong binding capabilities to the TMV capsid protein, with a binding affinity of 1.862 μM. Moreover, TMV-IN-9 significantly disrupts the integrity of TMV particles, thereby preventing the virus from infecting the host.</p>Formula:C20H20O8Color and Shape:SolidMolecular weight:388.37Amfenac
CAS:<p>Amfenac promotes apoptosis in ARPE-19 cell culture.</p>Formula:C15H13NO3Color and Shape:SolidMolecular weight:255.27AHR-10037
CAS:<p>AHR-10037, a NSAID, offers pain relief, fever reduction, safety, and low stomach risk, acting as a prodrug for COX inhibitors.</p>Formula:C15H13ClN2O2Purity:98%Color and Shape:SolidMolecular weight:288.73AZD4144
CAS:<p>AZD4144 is a potent and selective NLRP3 inhibitor (IC50 = 54 nM) that reducs IL-1β and IL-18 production for immune disorders.</p>Formula:C18H16F3N3O3Purity:99.02%Color and Shape:SoildMolecular weight:379.33Azacyclonol hydrochloride
CAS:<p>Azacyclonol hydrochloride can be used in the treatment of chronic schizophrenia.</p>Formula:C18H22ClNOColor and Shape:Off White Crystalline PowderMolecular weight:303.83D228
CAS:<p>D228 is an oral anti-inflammatory,inhibi B and T lymphocytes, down-regulation of MyD88/TRAF6/p38 and up-regulation of IL-10,inflammatory bowel disease (IBD).</p>Formula:C22H28O12Purity:99.91%Color and Shape:SolidMolecular weight:484.45Vopikitug
CAS:<p>Vopikitug is a humanized monoclonal antibody targeting IL-2RA with antitumor activity. It can be used to study cancer.</p>Purity:99.1% (SDS-PAGE); 96.5% (SEC-HPLC) - 99.1% (SDS-PAGE); 96.5% (SEC-HPLC)Color and Shape:LiquidEtokimab
CAS:<p>Etokimab (ANB-020) is a humanised monoclonal antibody targeting IL-33, neutrophil migration, atopic dermatitis, asthma, and sinusitis.</p>Purity:95%Color and Shape:LiquidAllopurinol Sodium
CAS:<p>Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.</p>Formula:C5H4N4NaOPurity:99.93%Color and Shape:SolidMolecular weight:159.1E3330
CAS:<p>E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.</p>Formula:C21H30O6Purity:99.52%Color and Shape:SolidMolecular weight:378.46Pelubiprofen
CAS:<p>Pelubiprofen is a non-steroidal anti-inflammatory agent and a COX-2 inhibitor, which effectively reduces PGE(2) production by inhibiting COX activity.</p>Formula:C16H18O3Purity:99.69%Color and Shape:SolidMolecular weight:258.31Catalase
CAS:<p>Catalase, an enzyme, metabolizes H2O2 and ROS; its expression and localization change significantly in tumors.</p>Purity:≥98%Color and Shape:Small Colorless Crystals Or Powder At Room Temperature Almost Odourless Small Colourless Crystals Or A White Crystalline PowderBay 65-1942 free base
CAS:<p>Bay 65-1942 free base is an inhibitor of ATP-competitive and selective IKKβ.</p>Formula:C22H25N3O4Purity:98%Color and Shape:SolidMolecular weight:395.45Z-VRPR-FMK
CAS:<p>Z-VRPR-FMK: irreversible MALT1 inhibitor, halts growth/invasion of diffused B-cell lymphoma by blocking NF-κB activation and MMP expression.</p>Formula:C31H49FN10O6Color and Shape:SolidMolecular weight:676.783-OH-Kynurenamine dihydroiodide
CAS:<p>3-OH-Kynurenamine dihydroiodide, the dihydroiodide form of 3-OH-Kynurenamine, functions as an activator of the aryl hydrocarbon receptor (AhR), thereby modulating the immune response. It enhances the expression of Ido1 and Tgfb1, reducing skin inflammation in psoriasis mouse models and kidney damage in nephrotoxic lupus mouse models .</p>Formula:C9H14I2N2O2Color and Shape:SolidMolecular weight:436.03BSP16
CAS:<p>BSP16: potent, oral STING agonist; boosts interferon genes; promising for cancer research.</p>Formula:C16H18O5SeColor and Shape:SolidMolecular weight:369.27Anti-inflammatory agent 21
CAS:<p>Compound 9o: orally active, low-toxicity anti-inflammatory; inhibits NO (IC50: 0.76 μM), blocks NF-κB/MAPK, reduces arthritis symptoms.</p>Formula:C24H21FO6Color and Shape:SolidMolecular weight:424.42COX-1/2-IN-1
CAS:<p>"COX-1/2-IN-2: Strong dual inhibitor of COX-1 (IC50 = 13.9 μM) and COX-2 (IC50 = 6.4 μM)."</p>Formula:C15H10BrClN2OColor and Shape:SolidMolecular weight:349.61QM385
CAS:<p>QM385 is a potent inhibitor of sepiapterin reductase (SPR)(IC50 of 1.49 nM).</p>Formula:C17H18F3N7O2Purity:98%Color and Shape:SolidMolecular weight:409.37β-Nor-lapachone
CAS:<p>β-Nor-lapachone is an antibiofilm agent of Candida glabrata.</p>Formula:C14H12O3Color and Shape:SolidMolecular weight:228.24AHR-6293
CAS:<p>AHR-6293 is used to distinguishing the effect of anti-platelet aggregating drug properties and the effect of anti-inflammatory properties.</p>Formula:C15H12ClNO3Color and Shape:SolidMolecular weight:289.71Keap1-Nrf2-IN-14
CAS:<p>Keap1-Nrf2-IN-14, a KEAP1-NRF2 inhibitor (IC50: 75 nM, Kd: 24 nM), boosts NRF2 gene expression, antioxidative and anti-inflammatory response.</p>Formula:C30H29NO8SColor and Shape:SolidMolecular weight:563.62COX-2/sEH-IN-1
CAS:<p>COX-2/sEH-IN-1, oral dual inhibitor: COX-2 (IC50=1.24 μM), sEH (IC50=0.40 μM); boosts anti-inflammatory action, cuts heart risk.</p>Formula:C23H18F3N5O3SColor and Shape:SolidMolecular weight:501.48Veledimex (S enantiomer)
CAS:<p>Veledimex S is the oral S enantiomer of a gene therapy promoter activator and CYP3A4/5 inhibitor.</p>Formula:C27H38N2O3Purity:98%Color and Shape:SolidMolecular weight:438.6PNRI-299
CAS:<p>PNRI-299 is a selective inhibitor of AP-1 transcription(IC50 of 20 uM ).</p>Formula:C21H15N5O4Purity:98%Color and Shape:SolidMolecular weight:401.37UPF-648 sodium salt
CAS:<p>UPF-648 sodium salt is an inhibitor of kynurenine 3-monooxygenase (KMO) and exhibits highly active at 1 uM (81 ± 10% KMO inhibition).</p>Formula:C11H8Cl2NaO3Purity:98%Color and Shape:SolidMolecular weight:282.07CD73-IN-1
CAS:<p>CD73-IN-1 is a CD73 inhibitor with anticancer activity.</p>Formula:C18H17N3O4SPurity:99.46% - 99.46%Color and Shape:SolidMolecular weight:371.41TMV-IN-1
CAS:<p>TMV-IN-1: a chalcone inhibits TMV with EC50s of 70.7 and 60.8 μg/mL, applicable in infection and tumor studies.</p>Formula:C28H26O4Color and Shape:SolidMolecular weight:426.5TLR7/8 agonist 6
CAS:<p>Compound 4: Imidazoquinoline, potent TLR7/8 agonist, IC50: 0.18μM (TLR7), 5.34μM (TLR8).</p>Formula:C24H27N5O2Color and Shape:SolidMolecular weight:417.5HSR1304
CAS:<p>HSR1304 (5d) inhibits NFκB, key in diseases like cancer, offering research potential.</p>Formula:C24H21ClN2O3Color and Shape:SolidMolecular weight:420.89NLRP3-IN-25
CAS:<p>NLRP3-IN-25 (compound 32), an orally available NLRP3 inhibitor, exhibits anti-inflammatory properties by attenuating renal injury in a mouse model of doxorubicin-induced glomerulonephritis and inhibiting IL-1β secretion in THP-1 cells, with an IC 50 value of 21 nM [1].</p>Formula:C17H19F3N4O5SColor and Shape:SolidMolecular weight:448.42BPK-29
CAS:<p>BPK-29 disrupts NR0B1 binding and modifies C274, inhibiting growth in KEAP1-mutant cancers.</p>Formula:C26H32ClN3O3Purity:98%Color and Shape:SolidMolecular weight:470TL8-506
CAS:<p>TL8-506 is a selective and potent TLR8 agonist that induces cytokine and chemokine production.TL8-506 alleviates inflammatory and autoimmune diseases.</p>Formula:C20H17N3O2Purity:95% - 99.97%Color and Shape:SolidMolecular weight:331.37Tin(IV) mesoporphyrin IX dichloride
CAS:<p>Tin(IV) mesoporphyrin IX dichloride (Stannsoporfin) is an effective heme oxygenase (HO) inhibitor used for the treatment of hyperbilirubinemia.</p>Formula:C34H36Cl2N4O4SnPurity:99.82%Color and Shape:SolidMolecular weight:754.29hDDAH-1-IN-1
CAS:<p>hDDAH-1-IN-1 is a selective non-amino acid catalytic site inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) (Ki: 18 μM).</p>Formula:C8H20N4OPurity:98%Color and Shape:SolidMolecular weight:188.27LY 178002
CAS:<p>LY 178002 inhibits 5-LPO (IC50: 0.6 μM), PLA2, and LTB4 production; weak on cyclooxygenase.</p>Formula:C18H25NO2SPurity:98%Color and Shape:SolidMolecular weight:319.46Anti-inflammatory agent 1
CAS:<p>Anti-inflammatory agent 1 is an anti-inflammatory compound.</p>Formula:C17H16O3SPurity:98%Color and Shape:SolidMolecular weight:300.37MIP-1072
CAS:<p>MIP-1072 is the prostate-specific membrane antigen inhibitor.</p>Formula:C19H26IN3O7Purity:98%Color and Shape:SolidMolecular weight:535.33GSK223
CAS:GSK223 is an iE-DAP-stimulated IL-8 release inhibitor via the NOD1 signaling pathway.Formula:C21H18FN3O3S2Purity:98%Color and Shape:SolidMolecular weight:443.51COX/5-LOX-IN-1
CAS:<p>Compound 6b is a potent dual inhibitor of COX/5-LOX with IC50s: 1.07μM (COX-1), 0.55μM (COX-2), 0.28μM (5-LOX) for inflammation research.</p>Formula:C18H30O3Color and Shape:SolidMolecular weight:294.43NCX1022
CAS:<p>NCX1022 is a NO-releasing derivative of Hydrocortisone. It is the most widely used anti-inflammatory drug for the treatment of skin inflammation.</p>Formula:C29H35NO9Purity:98%Color and Shape:SolidMolecular weight:541.59LC-R 505
CAS:<p>LC-R 505 is an anti-inflammatory.</p>Formula:C20H26N2O5SColor and Shape:SolidMolecular weight:406.5CK-119
CAS:<p>CK-119 inhibits IL-1, blocking corneal/conjunctival cell growth by halting DNA/RNA synthesis.</p>Formula:C21H23ClN4O5Color and Shape:SolidMolecular weight:446.88APC-0576
CAS:<p>APC-0576, an (S,S)-isomer, blocks NF-kappaB gene activation and may reduce inflammation in human cells.</p>Formula:C23H27N3O3Color and Shape:SolidMolecular weight:393.48FR20
CAS:<p>FR20 is a human microsomal prostaglandin synthase 1 (mPGES 1) inhibitor.</p>Formula:C31H25Cl2N3O2Color and Shape:SolidMolecular weight:542.46Anisodine hydrobromide
CAS:<p>Anisodine hydrobromide is an inhibitor of adenosine kinase.</p>Formula:C17H22BrNO5Color and Shape:White Crystals Or Crystalline PowderMolecular weight:400.27Oxyfenamate
CAS:<p>Oxyfenamate has anti-anxiety actions. It is also used in anxiety neuroses.</p>Formula:C11H15NO3Purity:98%Color and Shape:SolidMolecular weight:209.24IKK2-IN-4
CAS:<p>IKK2-IN-4(IKK2 Inhibitor VI) is a highly potent IKK-2 inhibitor with an IC50 value of 25 nM. IKK2-IN-4 inhibited the production of TNF-α in PBMC induced by LPS.</p>Formula:C12H11N3O2SPurity:>99.99%Color and Shape:SolidMolecular weight:261.3L 748780
CAS:<p>L 748780 is a selective inducible COX-2 inhibitor.</p>Formula:C19H14Cl3NO4Purity:98%Color and Shape:SolidMolecular weight:426.68ADU-S100 ammonium salt
CAS:<p>ADU-S100 ammonium salt is an activator of stimulator of interferon genes (STING).Cost-effective and quality-assured.</p>Formula:C20H30N12O10P2S2Purity:98%Color and Shape:SolidMolecular weight:724.6COX-2-IN-20
CAS:<p>COX-2-IN-20 (Compound 5d) is a selective and orally active inhibitor of COX-2 (IC 50 = 17.9 nM) with anti-inflammatory activity [1].</p>Formula:C11H9ClFN3O2Color and Shape:SolidMolecular weight:269.66Tiazotic acid
CAS:<p>Tiazotic acid is an agent with the activity of antioxidant.</p>Formula:C5H7N3O2SPurity:98%Color and Shape:SolidMolecular weight:173.19COX-2/5-LOX-IN-3
CAS:<p>COX-2/5-LOX-IN-3 inhibits COX-2/5-LOX with IC50s: COX-1 45.73μM, COX-2 5.45μM, 5-LOX 4.33μM; promising for inflammation research.</p>Formula:C17H16ClN3O2SColor and Shape:SolidMolecular weight:361.85ZXX2-77
CAS:<p>ZXX2-77 is a cyclooxygenase-1 inhibitor.</p>Formula:C13H13ClN2O2SPurity:98%Color and Shape:SolidMolecular weight:296.77MitoTEMPOL
CAS:<p>MitoTEMPOL is a mitochondria-targeted antioxidant that prevents septal dysfunction by reversing sepsis-induced decreases in mitochondrial function.</p>Formula:C32H42BrNO2PColor and Shape:SolidMolecular weight:583.56NCX-6560
CAS:<p>NCX-6560 is a novel NO-releasing derivative of atorvastatin, with those of atorvastatin.</p>Formula:C37H42FN3O8Color and Shape:SolidMolecular weight:675.74Fagaramide
CAS:<p>Fagaramide possesses Antiplasmodial activity.</p>Formula:C14H17NO3Purity:98%Color and Shape:SolidMolecular weight:247.29NLRP3-IN-13
CAS:<p>NLRP3-IN-13 is an NLRP3 inhibitor that inhibits NLRP3-associated inflammation.NLRP3-IN-13 can be used in the study of neurological disorders and inflammation.</p>Formula:C19H15N3O3SPurity:99.16%Color and Shape:SolidMolecular weight:365.41LY 150310
CAS:<p>LY 150310, a histamine H1-receptor antagonist, can alter prostanoid concentrations in vitro and in vivo.</p>Formula:C13H14N2Color and Shape:SolidMolecular weight:198.26L 669083
CAS:<p>L 669083 is two classes of potent leukotriene biosynthesis inhibitors photoaffinity analogue.</p>Formula:C29H29IN4O5SPurity:98%Color and Shape:SolidMolecular weight:672.54C5aR-IN-2
CAS:<p>C5aR-IN-2, a potent C5aR inhibitor, shows promise for researching inflammatory diseases.</p>Formula:C36H40FN5O2Color and Shape:SolidMolecular weight:593.73Keap1-Nrf2-IN-13
CAS:<p>Keap1-Nrf2-IN-13 is a PPI inhibitor (IC50: 0.15 μM) that binds Keap1 strongly, useful for oxidative stress and inflammation research.</p>Formula:C28H32N2O10S2Color and Shape:SolidMolecular weight:620.69c-di-AMP
CAS:<p>c-di-AMP (Cyclic diadenylate) is a STING agonist. It binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway.</p>Formula:C20H24N10O12P2Purity:98%Color and Shape:SolidMolecular weight:658.41MIF-IN-3
CAS:<p>MIF-IN-3 inhibits MIF; useful in immunoinflammation research. (WO2021258272A1, compound 31)</p>Formula:C20H20N4O5SColor and Shape:SolidMolecular weight:428.46BC12-4
CAS:<p>BC12-4 is a novel potent inhibitor of IL-2 secretion, it has potent immunomodulatory activity.</p>Formula:C19H14N2O3Color and Shape:SolidMolecular weight:318.33STING modulator-4
CAS:<p>STING modulator-4: competitive, Ki=0.0933 μM (R232H STING), EC50 >10 μM (p-IRF3, THP-1 cells).</p>Formula:C17H18N8OColor and Shape:SolidMolecular weight:350.38L-Kynurenine sulfate
CAS:<p>L-Kynurenine sulfate activates AHR, leading naive T cells to anti-inflammatory Treg phenotype.</p>Formula:C10H14N2O7SColor and Shape:SolidMolecular weight:306.29GCPII-IN-1 TFA
CAS:<p>GCPII-IN-1 TFA (compound 2) is an inhibitor scaffold for glutamate carboxypeptidase II (GCPII, PSMA) with a Ki of 44.3±2.4 nM for use in prostate cancer.</p>Formula:C14H22F3N3O9Color and Shape:SoildMolecular weight:433.34OPC-163493
CAS:<p>OPC-163493 is an orally active, liver-targeted mitochondrial uncoupling agent that diminishes Δψ (delta psi) and mitochondrial ROS (reactive oxygen species)</p>Formula:C14H8F3N5SPurity:98%Color and Shape:SolidMolecular weight:335.31BBS-4
CAS:<p>BBS-4 inhibits NOS2 dimerization (IC50: 0.49 nM), guarding mice against sepsis-related heart issues.</p>Formula:C22H24N6O3Color and Shape:SolidMolecular weight:420.46Naproxen etemesil
CAS:<p>Naproxen, a COX-1/2 inhibitor, has IC50s of 8.72/5.15 μM. Its prodrug, naproxen etemesil, is lipophilic and converts to active form upon absorption.</p>Formula:C17H20O5SPurity:98%Color and Shape:SolidMolecular weight:336.4HPGDS inhibitor 3
CAS:<p>HPGDS inhibitor 3: oral, potent (IC50=9.4 nM; EC50=42 nM), selective, no CNS toxicity, good pharmacokinetics, anti-inflammatory.</p>Formula:C21H27N3O2Color and Shape:SolidMolecular weight:353.46IRAK4-IN-17
CAS:<p>IRAK4-IN-17 is a potent IRAK4 inhibitor with a 1.3 nM IC50, key for DLBCL research.</p>Formula:C17H20F2N8OColor and Shape:SolidMolecular weight:390.39T-5342126
CAS:<p>T-5342126: TLR4 antagonist, lowers LPS-induced NO in cells (IC50=27.8 μM) & cytokines in blood, cuts ethanol intake & Iba1 in mice.</p>Formula:C25H32ClN3O3Color and Shape:SolidMolecular weight:457.99TYT-1
CAS:<p>TYT-1 is a West Nile virus (WNV) inhibitor, antiviral (IC₅₀ = 0.7 mM) by blocking the pre-assembly replication step following viral entry into cells.</p>Formula:C21H17N3O2S3Purity:98.49%Color and Shape:SolidMolecular weight:439.57Tenosal
CAS:<p>Tenosal obtained by esterifying salicylic acid with 2-thiophene-carboxylic acid, and with analgesic and antipyretic properties, anti-inflammatory.</p>Formula:C12H8O4SPurity:98%Color and Shape:SolidMolecular weight:248.25CAY10575
CAS:<p>CAY10575 (IKK2-IN-3) is a potent IKK2 inhibitor with potential anti-inflammatory activity for the study of inflammatory and endocrine diseases.</p>Formula:C22H21N3O6S2Color and Shape:SolidMolecular weight:487.55Nω-Propyl-L-arginine hydrochloride
CAS:<p>Highly selective and potent inhibitor of nNOS (Ki = 57 nM). Displays 3158-fold and 149-fold selectivity over iNOS and eNOS respectively. Hypotensive in vivo.</p>Formula:C9H21ClN4O2Color and Shape:SolidMolecular weight:252.74NLRP3-IN-16
CAS:<p>NLRP3-IN-16: potent NLRP3 inflammasome inhibitor; IC50=0.065μM; curbs IL-1β; used in inflammation studies.</p>Formula:C25H25NO5Purity:98%Color and Shape:SolidMolecular weight:419.478A8
CAS:<p>8A8 is a potent NO inhibitor with proinflammatory factor properties, exhibiting an IC50 of 4.7 μM.</p>Formula:C36H37BrClN5O9Purity:98%Color and Shape:SolidMolecular weight:799.06BCX 1470
CAS:<p>BCX 1470 inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respectively.</p>Formula:C14H10N2O2S2Purity:98%Color and Shape:SolidMolecular weight:302.37IMD-biphenylB
CAS:<p>IMD-biphenylB: Potent NF-κB inhibitor, curbs tumor growth with low inflammation and toxicity.</p>Formula:C35H33N5O3Purity:98%Color and Shape:SolidMolecular weight:571.67Bifenazate
CAS:<p>Bifenazate is a positive allosteric modulator of GABA receptor. Bifenazate is an acaricide that controls 100% of mites at a concentration of 25 ppm.</p>Formula:C17H20N2O3Purity:99.62%Color and Shape:Solid CrystallineMolecular weight:300.35NBC 19
CAS:<p>Potent NLRP3 inflammasome inhibitor (IC50 = 60-80 nM). Inhibits nigericin- and ATP-induced IL-1β release.</p>Formula:C24H26BCl3N2O2Color and Shape:SolidMolecular weight:491.65Stigmane B
<p>Stigmane B activates Nrf2, decreases apoptosis and ROS, boosts antioxidants, and is neuroprotective.</p>Formula:C21H30O4Color and Shape:SolidMolecular weight:346.46STING agonist-30
CAS:<p>STING agonist-30 is a STING agonist that stimulates STING-dependent immune activation and inhibits HSV, rotavirus and SARS-CoV-2.</p>Formula:C15H16N4O8Purity:98.80%Color and Shape:SolidMolecular weight:380.31Dibenzo(a,i)pyrene
CAS:<p>Dibenzo(a, i)pyrene is a polycyclic aromatic hydrocarbon with potent carcinogenic activity.</p>Formula:C24H14Color and Shape:Greenish-Yellow Needles Prisms Or Lamellae Dibenz[A I]Pyrene Is A Colorless Solid Water InsolubleMolecular weight:302.37CD38 inhibitor 3
CAS:<p>CD38 Inhibitor 3 (compound 1), with an IC50 of 11 nM, is a potent agent that enhances mitochondrial biogenesis, diminishes lactate levels, and augments both NAD</p>Formula:C16H14F3N7O3Purity:98%Color and Shape:SolidMolecular weight:409.32NLRP3-IN-20
CAS:<p>NLRP3-IN-20 (compound 11) is an orally administered inhibitor targeting the NLRP3 inflammasome, exhibiting potent inhibition with an IC50 of 25 nM against IL-1β</p>Formula:C22H27N3O3SPurity:98%Color and Shape:SolidMolecular weight:413.53iNOS inhibitor-10
CAS:<p>iNOS Inhibitor-10, with an IC50 of 65 nM, exhibits antiproliferative effects on triple-negative breast cancer cells [1].</p>Formula:C22H23N3O2SPurity:98%Color and Shape:SolidMolecular weight:393.5COX-2-IN-32
CAS:<p>COX-2-IN-32 (Compound 2f) is a dual inhibitor of iNOS and COX-2, known to downregulate NF-κB expression.</p>Formula:C25H24O6Purity:98%Color and Shape:SolidMolecular weight:420.45SZM679
<p>SZM679: Oral RIPK1 inhibitor, Kd 8.6 nM, weak RIPK3 affinity (>5000 nM). Reduces inflammation, Tau phosphorylation in AD research.</p>Formula:C27H18F5N3O5SPurity:98%Color and Shape:SolidMolecular weight:591.51NIC-0102
CAS:<p>NIC-0102 is an orally active proteasome inhibitor (pIC50:7.55) that exhibits specific inhibition of NLRP3 inflammatory vesicle activation. Inhibitory effect.</p>Formula:C21H25BF2N2O4Color and Shape:SolidMolecular weight:418.24
