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Immunology and Inflammation

Immunology and Inflammation

Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.

Subcategories of "Immunology and Inflammation"

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Found 3054 products of "Immunology and Inflammation"

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  • CCT374705

    CAS:
    <p>CCT374705, an orally active BCL6 inhibitor, exhibits potent antiproliferative effects in vitro and effectively inhibits tumor growth in a lymphoma xenograft</p>
    Formula:C21H18ClF3N4O2
    Color and Shape:Solid
    Molecular weight:450.84
  • GW274150 phosphate

    CAS:
    <p>GW274150 phosphate is a selective, orally active iNOS inhibitor with an IC50 of 0.2 μM. It mitigates experimental renal ischaemia-reperfusion injury.</p>
    Formula:C8H20N3O6PS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:317.3
  • NLRP3-IN-17

    CAS:
    <p>NLRP3-IN-17 is a potent, selective, and orally active inhibitor of the NLRP3 inflammasome, demonstrating an IC50 of 7 nM.</p>
    Formula:C21H22N4O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:394.49
  • Argininosuccinic acid disodium

    CAS:
    <p>Argininosuccinic acid disodium, involved in the urea cycle's fourth step, is cleaved by argininosuccinate lyase (ASL) into arginine and fumarate.</p>
    Formula:C10H16N4Na2O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:334.24
  • Glu-urea-Glu-NHS ester

    CAS:
    <p>Compound 21, Glu-urea-Glu-NHS ester, an activated N-hydroxysuccinamide (NHS) ester derivative of Glu-urea-Glu, serves as a pharmacophore for conjugation to prostate specific membrane antigen (PSMA) inhibitors [1].</p>
    Formula:C27H43N3O11
    Color and Shape:Solid
    Molecular weight:585.64
  • EG01377

    CAS:
    <p>EG01377 is a NRP1 antagonist with antiangiogenic, antimigratory, and antitumor activity, Kd 1.32 μM, IC50s 609 nM for NRP1-a1/b1, inactive on NRP2.</p>
    Formula:C26H30N6O6S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:586.68
  • IRAK inhibitor 3

    CAS:
    <p>IRAK inhibitor 3 is an interleukin-1 (IL-1) receptor-associated kinase (IRAK) modulator.</p>
    Formula:C21H21N5O4S
    Purity:98.86%
    Color and Shape:Solid
    Molecular weight:439.49
  • cGAS-IN-1

    CAS:
    <p>cGAS-IN-1 (compound C20), a flavonoid that acts as a Cyclic GMP-AMP Synthase (cGAS) inhibitor, demonstrates IC50 values of 2.28 μM for human cGAS and 1.44 μM</p>
    Formula:C18H19NO8
    Color and Shape:Solid
    Molecular weight:377.35
  • CAY10464

    CAS:
    <p>CAY10464 (AHR antagonist 7) is an AHR antagonist for the study of cancer and metabolic diseases.</p>
    Formula:C15H12Cl2O
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:279.16
  • ST 2825

    CAS:
    <p>ST 2825 is a specific MyD88 dimerization inhibitor. ST2825 inhibition of IL-1β-mediated activation of NF-κB transcriptional activity.</p>
    Formula:C27H28Cl2N4O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:591.51
  • GBT1118

    CAS:
    <p>GBT1118 is an orally active allosteric modulator of haemoglobin oxygen affinity, enhancing tolerance to acute severe hypoxia and suitable for hypoxia research.</p>
    Formula:C19H20N2O4
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:340.37
  • NLRP3-IN-9

    CAS:
    <p>NLRP3-IN-9 (INF-4E) irreversibly inhibits NLRP3 ATPase, caspase-1, and prevents pyroptosis in THP-1 cells.</p>
    Formula:C12H13ClO3
    Purity:99.64%
    Color and Shape:Solid
    Molecular weight:240.68
  • Thromboxane B3

    CAS:
    <p>Thromboxane B3 (TXB3), the stable hydrolysis product of TXA3, is synthesized from eicosapentaenoic acid (EPA) through the action of COX and thromboxane synthase enzymes. This compound is biosynthesized in several tissues, including seminal vesicles, lungs, polymorphonuclear leukocytes (PMNL), and ocular tissues.</p>
    Formula:C20H32O6
    Color and Shape:Solid
    Molecular weight:368.5
  • TLR7/8 agonist 8

    CAS:
    <p>TLR7/8 agonist 8 (compound 24m) is a potent dual agonist for toll-like receptors 7 and 8 (TLR7/8), exhibiting half-maximal effective concentrations (EC50s) of</p>
    Formula:C24H30N6O
    Color and Shape:Solid
    Molecular weight:418.53
  • Ro26-4550

    CAS:
    <p>Ro26-4550 is a competitive reversible inhibitor of interleukin-2 (IL-2) binding to IL-2R α-subunit (IC50 = 3 μM).</p>
    Formula:C26H30N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:446.54
  • TLR9-IN-1

    CAS:
    <p>TLR9-IN-1: selective, potent human TLR9 inhibitor (IC50: 7 nM), useful for researching immune-related diseases.</p>
    Formula:C23H31N7O
    Color and Shape:Solid
    Molecular weight:421.54
  • IRAK4-IN-6

    CAS:
    <p>IRAK4-IN-6 is an oral IRAK4 inhibitor with a 4 nM IC50, targeting MyD88 L265P mutant DLBCL.</p>
    Formula:C25H32N10O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:504.59
  • MKA031

    CAS:
    <p>MKA031 (compound 6y) is a non-competitive inhibitor of macrophage migration inhibitory factor (MIF), exhibiting an IC50 of 1.7 μM.</p>
    Formula:C21H17N5O2S
    Color and Shape:Solid
    Molecular weight:403.46
  • CD38 inhibitor 2

    CAS:
    <p>CD38 inhibitor 2 is a potent CD38 inhibitor ( IC 50 = 0.01 ~ 0.1 μΜ).</p>
    Formula:C19H24N6O3
    Color and Shape:Solid
    Molecular weight:384.43
  • AMPCP

    CAS:
    <p>AMPCP is an Ecto-5'-nucleotidase (CD73) inhibitor.</p>
    Formula:C11H15N5Na2O9P2
    Color and Shape:Solid
    Molecular weight:469.19