CymitQuimica logo
Immunology and Inflammation

Immunology and Inflammation

Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.

Subcategories of "Immunology and Inflammation"

Show 11 more subcategories

Found 3045 products of "Immunology and Inflammation"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • NLRP3-IN-58
    Targetmol
    + Info

    NLRP3-IN-58

    CAS:
    <p>NLRP3-IN-58 (Compound DS15) acts as an inhibitor of NLRP3 inflammasome activation, with an IC50 value of 3.85 μM, and is capable of inhibiting 33% of IL-1β release at a concentration of 10 μM.</p>
    Formula:C22H18ClN3O3S
    Color and Shape:Solid
    Molecular weight:439.92

    Ref: TM-T200969

  • STING agonist-42
    Targetmol
    + Info

    STING agonist-42

    CAS:
    <p>STINGagonist-42 (compound 8a) is a potent STING agonist. It activates STING in THP1 and RAW 264.7 cells, with EC50 values of 0.06 μM and 14.15 μM, respectively.</p>
    Formula:C17H8F2LiN5O3
    Color and Shape:Solid
    Molecular weight:375.22

    Ref: TM-T207376

  • NLRP3-IN-70
    Targetmol
    + Info

    NLRP3-IN-70

    CAS:
    <p>NLRP3-IN-70 (Compound 5m) is an inhibitor of the NLRP3 inflammasome with low oral bioavailability. It binds directly to the NACHT domain of the NLRP3 protein, thereby blocking its interaction with ASC, which inhibits ASC oligomerization and the assembly of the NLRP3 inflammasome. NLRP3-IN-70 is applicable in studies on sepsis and non-alcoholic steatohepatitis.</p>
    Formula:C23H23NO5
    Color and Shape:Solid
    Molecular weight:393.432

    Ref: TM-T205527

  • MG-T-19
    Targetmol
    + Info

    MG-T-19

    CAS:
    <p>MG-T-19, a TIM-3 inhibitor, inhibit the interaction of TIM-3 with PtdSer, CEACAM1, and Gal-9, and increased the production of TNF-α and IFN-γ in PBMCs.</p>
    Formula:C18H8Br2ClF3N4O2S
    Purity:99.14%
    Color and Shape:Solid
    Molecular weight:596.6

    Ref: TM-T201721

  • STING-IN-15
    Targetmol
    + Info

    STING-IN-15

    CAS:
    <p>STING-IN-15 (compound 66) is a potent STING inhibitor, effectively suppressing human and mouse STING with IC50 values of 116 nM and 96.3 nM, respectively. In the REX1 D18N mouse model, STING-IN-15 significantly reduces tissue damage and inflammation.</p>
    Formula:C20H14F2N4O3
    Color and Shape:Solid
    Molecular weight:396.35

    Ref: TM-T207666

  • NLRP3-IN-80
    Targetmol
    + Info

    NLRP3-IN-80

    CAS:
    <p>NLRP3-IN-80 (Compound 1) is an NLRP3 inhibitor useful for research into inflammatory aging.</p>
    Formula:C24H22F2N4O3
    Color and Shape:Solid
    Molecular weight:452.45

    Ref: TM-T207648

  • NP3-146 sodium
    Targetmol
    + Info

    NP3-146 sodium

    CAS:
    <p>NP3-146 sodium is an inhibitor of the NLRP3 inflammasome.</p>
    Formula:C20H26ClN2NaO5S
    Color and Shape:Solid
    Molecular weight:464.94

    Ref: TM-T200987

  • AS2690168 hydrochloride
    Targetmol
    + Info

    AS2690168 hydrochloride

    CAS:
    <p>AS2690168 hydrochloride is an orally active inhibitor of RANKL signaling that can suppress RANKL-induced osteoclastogenesis in RAW264 cells. AS2690168 is applicable in research related to pathological bone resorption.</p>
    Formula:C17H15Cl2F3N4O
    Color and Shape:Solid
    Molecular weight:419.228

    Ref: TM-T204813

  • mPGES1-IN-9
    Targetmol
    + Info

    mPGES1-IN-9

    CAS:
    <p>mPGES1-IN-9 (compound 1_8) is an mPGES1 inhibitor with an IC50 of 0.5 μM and is utilized in anti-inflammatory research.</p>
    Formula:C25H18N4OS
    Color and Shape:Solid
    Molecular weight:422.502

    Ref: TM-T204717

  • FK-565
    Targetmol
    + Info

    FK-565

    CAS:
    <p>FK-565 is a ligand of nucleotide-binding oligomerization domain-1 (NOD1) that induces a mouse model of arteritis.</p>
    Formula:C22H38N4O9
    Color and Shape:Solid
    Molecular weight:502.559

    Ref: TM-T204684

  • AS2690168 (free base)
    Targetmol
    + Info

    AS2690168 (free base)

    CAS:
    <p>AS2690168 freebase is an orally active inhibitor of RANKL signaling, capable of suppressing RANKL-induced osteoclastogenesis in RAW264 cells. AS2690168 is applicable in research related to pathological bone resorption.</p>
    Formula:C17H13F3N4O
    Color and Shape:Solid
    Molecular weight:346.306

    Ref: TM-T204137

  • (Rel)-Factor B-IN-5
    Targetmol
    + Info

    (Rel)-Factor B-IN-5

    CAS:
    <p>(Rel)-Factor B-IN-5 is a complement factor B inhibitor that can be used to study diseases associated with activation of the alternative complement pathway.</p>
    Formula:C27H32N2O4
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:448.55

    Ref: TM-T62689

  • CD73-IN-19
    Targetmol
    + Info

    CD73-IN-19

    CAS:
    <p>CD73-IN-19 (Compound 4ab) is an inhibitor of CD73, demonstrating a 44% inhibition rate of CD73 enzyme activity at 100 μM. It entirely counters T cell proliferation blockade triggered by TCR activation (induced by CD73 activity) at 10 μM and 100 μM and inhibits hA2A receptor activity in HEK-293 cells with a Ki of 3.31 μM. CD73-IN-19 holds potential for research in the field of immune diseases.</p>
    Formula:C18H17N3O3S
    Color and Shape:Solid
    Molecular weight:355.411

    Ref: TM-T204632

  • LHC-165
    Targetmol
    + Info

    LHC-165

    CAS:
    <p>LHC-165 is an agonist of TLR7. It also has the potential to treat solid tumors.</p>
    Formula:C29H32F2N3O7P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:603.55

    Ref: TM-T15751

  • G108
    Targetmol
    + Info

    G108

    CAS:
    <p>G108 is an inhibitor of human cGAS and is used in the study of autoimmune diseases associated with human cGAS.</p>
    Formula:C16H14Cl2N4O2
    Purity:99.13% - 99.75%
    Color and Shape:Solid
    Molecular weight:365.21

    Ref: TM-T69663

  • SP4206
    Targetmol
    + Info

    SP4206

    CAS:
    <p>SP4206 is an interaction inhibitor of IL-2/IL-2Rα (IL-2 and IL-2Rα with Kd of 70 nM and 10 nM,respectively)</p>
    Formula:C30H37Cl2N7O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:662.56

    Ref: TM-T12982

  • oxLig-1
    Targetmol
    + Info

    oxLig-1

    CAS:
    <p>OxLig-1 (7-Ketocholesteryl-9-carboxynonanoate) constitutes a lipid component of oxidized low-density lipoprotein (oxLDL) and serves as a critical ligand for β-glycoprotein I (β(2)-GPI). It induces nuclear translocation by activating the NF-κB pathway. Additionally, oxLig-1 is utilized in the study of atherosclerosis (AS).</p>
    Formula:C36H58O5
    Color and Shape:Solid
    Molecular weight:570.84

    Ref: TM-T201276

  • CymitQuimica logo
    Targetmol
    + Info

    Anti-inflammatory agent 6

    <p>Anti-inflammatory agent 6 blocks IKKα/β, IκBα, and NF-κB p65 phosphorylation, key to controlling inflammation.</p>
    Formula:C22H20O12
    Color and Shape:Solid
    Molecular weight:476.39

    Ref: TM-T63107

  • CymitQuimica logo
    Targetmol
    + Info

    OP-5244 sodium

    <p>OP-5244 sodium: potent oral CD73 inhibitor (IC50: 0.25 nM), potential in cancer research by hindering adenosine, reversing immunosuppression.</p>
    Formula:C19H28ClN5NaO9P
    Color and Shape:Solid
    Molecular weight:559.87

    Ref: TM-T63956

  • RGT-068A
    Targetmol
    + Info

    RGT-068A

    CAS:
    <p>RGT-068A is a potent, selective and oral bioavailable MALT1 inhibitor .</p>
    Formula:C17H16ClN9O2
    Color and Shape:Solid
    Molecular weight:413.82

    Ref: TM-T73389