Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(136 products)
- CXCR(148 products)
- Cell wall(5 products)
- IL Receptor(112 products)
- IκB/IKK(60 products)
- LTR(3 products)
- MALT(23 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(444 products)
- NOD(17 products)
- NOS(63 products)
- Nrf2(78 products)
- PGE Synthase(31 products)
- ROS(69 products)
- TGF-beta/Smad(58 products)
- TLR(66 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
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Found 3034 products of "Immunology and Inflammation"
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AHR antagonist 5 hemimaleate
<p>Potent oral AHR antagonist with IC50 < 0.5 μM, hinders tumor growth with anti-PD-1.</p>Formula:C29H28FN7O4Color and Shape:SolidMolecular weight:499.55CD73-IN-7
CAS:<p>CD73-IN-7: potent inhibitor of CD73, blocks adenosine production to treat tumors.</p>Formula:C13H11ClN4O2Color and Shape:SolidMolecular weight:290.7Heme Oxygenase-2-IN-1
<p>Heme Oxygenase-2-IN-1 is a selective HO-2 inhibitor with IC50s: 14.9 μM (HO-1), 0.9 μM (HO-2).</p>Formula:C19H17N3O2Color and Shape:SolidMolecular weight:319.36Hetrombopag olamine
CAS:<p>Hetrombopag olamine is a non-peptide thrombopoietin (TPO) receptor agonist with oral activity.</p>Formula:C29H36N6O7Purity:98%Color and Shape:SolidMolecular weight:580.63iNOs-IN-1
<p>iNOs-IN-1 (YPW) is a strong iNOS inhibitor with dose-dependent anti-inflammatory properties, reducing IL-6, iNOS, and NO levels.</p>Formula:C25H30N4O5Color and Shape:SolidMolecular weight:466.53RuDiOBn
CAS:<p>RuDiOBn exhibits low antioxidant activity by scavenging DPPH and ABTS free radicals with scavenging rates of 13.2% and 5.9% at a concentration of 100 μg/mL. It inhibits collagen glycation and reduces the formation of advanced glycation end-products (AGE) with an IC50 of 2.45 μg/mL. RuDiOBn also enhances fibroblast proliferation and migration, stimulates collagen synthesis, and aids in skin repair and regeneration while inhibiting collagenase.</p>Formula:C29H22O7Color and Shape:SolidMolecular weight:482.481NP3-146 sodium
CAS:<p>NP3-146 sodium is an inhibitor of the NLRP3 inflammasome.</p>Formula:C20H26ClN2NaO5SColor and Shape:SolidMolecular weight:464.94ODN 21158
CAS:<p>ODN 21158 is a potent, non-cytotoxic inhibitor of G-modified TLR3 and TLR9. ODN 21158 dose-dependently inhibits IFN-α secretion.</p>Color and Shape:SolidNLRP3-IN-58
CAS:<p>NLRP3-IN-58 (Compound DS15) acts as an inhibitor of NLRP3 inflammasome activation, with an IC50 value of 3.85 μM, and is capable of inhibiting 33% of IL-1β release at a concentration of 10 μM.</p>Formula:C22H18ClN3O3SColor and Shape:SolidMolecular weight:439.92IRAK4-IN-14
CAS:<p>IRAK4-IN-14 is a selective, potent, orally active IRAK4 inhibitor (IC50: 0.003 μM) with favorable PK parameters in rats and mice. effect.</p>Formula:C25H28FN9OColor and Shape:SolidMolecular weight:489.55C5aR-IN-3
CAS:<p>C5aR-IN-3, a potent C5aR inhibitor, may treat autoimmune and inflammatory diseases.</p>Formula:C36H40FN5O3Color and Shape:SolidMolecular weight:609.73IRAK4-IN-19
<p>IRAK4-IN-19, an IRAK4 inhibitor (IC50: 4.3 nM), hampers IL23 synthesis and arthritis progression.</p>Formula:C25H26F2N8OColor and Shape:SolidMolecular weight:492.52Ocadusertib
CAS:<p>Ocadusertib is an effective inhibitor of the serine/threonine kinase receptor-interacting protein kinase 1 (RIPK1).</p>Formula:C25H25N5O4Color and Shape:SolidMolecular weight:459.50NLRP3-IN-56
CAS:<p>NLRP3-IN-56 (compound 062) is an inhibitor of NLRP3. It effectively suppresses the secretion of IL-1β in THP-1 cells, demonstrating an IC50 of 9.7 nM. NLRP3-IN-56 is useful for research into NLRP3-mediated symptoms and/or diseases.</p>Formula:C20H18ClN3O3Color and Shape:SolidMolecular weight:383.83CD73-IN-13
<p>CD73-IN-13, a potent CD73 inhibitor, may be developed for tumor-related disease treatment.</p>Formula:C13H11F3N4O2Color and Shape:SolidMolecular weight:312.25RGT-068A
CAS:<p>RGT-068A is a potent, selective and oral bioavailable MALT1 inhibitor .</p>Formula:C17H16ClN9O2Color and Shape:SolidMolecular weight:413.82OP-5244 sodium
<p>OP-5244 sodium: potent oral CD73 inhibitor (IC50: 0.25 nM), potential in cancer research by hindering adenosine, reversing immunosuppression.</p>Formula:C19H28ClN5NaO9PColor and Shape:SolidMolecular weight:559.87oxLig-1
CAS:<p>OxLig-1 (7-Ketocholesteryl-9-carboxynonanoate) constitutes a lipid component of oxidized low-density lipoprotein (oxLDL) and serves as a critical ligand for β-glycoprotein I (β(2)-GPI). It induces nuclear translocation by activating the NF-κB pathway. Additionally, oxLig-1 is utilized in the study of atherosclerosis (AS).</p>Formula:C36H58O5Color and Shape:SolidMolecular weight:570.84TLR7/8 antagonist 1
<p>Compound 16c, an imidazoquinoline, is a TLR7/8 agonist; IC50: 3.91 μM (TLR7), 2.19 μM (TLR8); targets TLR-2050 for disease treatment.</p>Formula:C24H27N5O2Color and Shape:SolidMolecular weight:417.5STING agonist-20
CAS:<p>STING agonist-20: potent, aids in XMT-2056 synthesis, used as a cancer vaccine adjuvant.</p>Formula:C36H39N11O8Color and Shape:SolidMolecular weight:753.76
