Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(140 products)
- CXCR(159 products)
- Cell wall(5 products)
- IL Receptor(110 products)
- IκB/IKK(58 products)
- LTR(3 products)
- MALT(25 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(415 products)
- NOD(23 products)
- NOS(61 products)
- Nrf2(82 products)
- PGE Synthase(31 products)
- ROS(70 products)
- TGF-beta/Smad(63 products)
- TLR(73 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
Show 11 more subcategories
Found 3385 products of "Immunology and Inflammation"
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IRAK4-IN-15
CAS:IRAK4-IN-15: selective IRAK4 inhibitor, IC50 0.002 μM, good PK, low clearance, synergizes with Acalabrutinib in MyD88/CD79 mutant ABC-DLBCL.Formula:C25H29FN10Color and Shape:SolidMolecular weight:488.56SMW139
CAS:SMW139 is a selective allosteric antagonist of the P2X7 receptor, exhibiting a Ki value of 32 nM for human P2X7R. In rat liver microsomes, its half-life is 47 minutes. SMW139 is applicable in research related to inflammation, Alzheimer's disease, and multiple sclerosis.Formula:C19H21ClF3NO2Color and Shape:SolidMolecular weight:387.824CD73-IN-18
CAS:CD73-IN-18 (compound 35j) is an orally effective inhibitor of the extracellular 5'-nucleotidase (CD73) enzyme. It can be utilized in anticancer research.Formula:C20H17N5O3Color and Shape:SolidMolecular weight:375.38Imipramine Blue chloride
Imipramine Blue chloride is an effective anti-invasive agent capable of inhibiting glioma invasion. It suppresses the production of reactive oxygen species (reactive oxygen species) mediated by NADPH oxidase.Formula:C40H51ClN4Color and Shape:SolidMolecular weight:623.31STING agonist-20
CAS:STING agonist-20: potent, aids in XMT-2056 synthesis, used as a cancer vaccine adjuvant.Formula:C36H39N11O8Color and Shape:SolidMolecular weight:753.76ZMC3
CAS:ZMC3 (NSC328784), a zinc chelator, exhibits properties as a zinc metallochaperone. It shows enhanced sensitivity in cells with the p53-R175H mutation and increases the cellular levels of ROS (reactive oxygen species).Formula:C17H20N6SeColor and Shape:SolidMolecular weight:387.34TLR7/8 antagonist 1
Compound 16c, an imidazoquinoline, is a TLR7/8 agonist; IC50: 3.91 μM (TLR7), 2.19 μM (TLR8); targets TLR-2050 for disease treatment.Formula:C24H27N5O2Color and Shape:SolidMolecular weight:417.5Fluopimomide
CAS:Fluopimomide (LH2010A), a powerful insecticide, is extensively utilized in the control of agricultural pests. It adversely affects the growth, locomotor behavior, reproduction, and lifespan of nematodes. Concurrently, it leads to increased production of reactive oxygen species (ROS), accumulation of lipids and lipofuscins, as well as a rise in malondialdehyde content. Additionally, Fluopimomide inhibits the antioxidant system of nematodes.Formula:C15H8ClF7N2O2Color and Shape:SolidMolecular weight:416.68MGD-28
CAS:MGD-28 is a Cullin-CRBN-dependent IKZF family protein degrader for IKZF1 (Ikaros), IKZF2 (Helios), IKZF3 (Aiolos) ,and CK1α, antiproliferative.Formula:C33H34FN7O3Purity:99.39%Color and Shape:SolidMolecular weight:595.67C5aR-IN-3
CAS:C5aR-IN-3, a potent C5aR inhibitor, may treat autoimmune and inflammatory diseases.Formula:C36H40FN5O3Color and Shape:SolidMolecular weight:609.73RGT-068A
CAS:RGT-068A is a potent, selective and oral bioavailable MALT1 inhibitor .Formula:C17H16ClN9O2Color and Shape:SolidMolecular weight:413.82IRAK4-IN-19
IRAK4-IN-19, an IRAK4 inhibitor (IC50: 4.3 nM), hampers IL23 synthesis and arthritis progression.Formula:C25H26F2N8OColor and Shape:SolidMolecular weight:492.52OP-5244 sodium
OP-5244 sodium: potent oral CD73 inhibitor (IC50: 0.25 nM), potential in cancer research by hindering adenosine, reversing immunosuppression.Formula:C19H28ClN5NaO9PColor and Shape:SolidMolecular weight:559.87MALT1-IN-11
CAS:MALT1-IN-11: MALT1 inhibitor, IC50 <10-100 nM, reduces IL10, for cancer/autoimmune research.Formula:C20H16F4N8OColor and Shape:SolidMolecular weight:460.39Anti-inflammatory agent 6
Anti-inflammatory agent 6 blocks IKKα/β, IκBα, and NF-κB p65 phosphorylation, key to controlling inflammation.Formula:C22H20O12Color and Shape:SolidMolecular weight:476.39YM-I-26
CAS:YM-I-26 is a selective inhibitor of the NLRP3 inflammasome. This compound enhances the phagocytic activity of β-amyloid in murine microglial BV2 cells and reduces the production of IL-1β and IL-10. YM-I-26 is useful for research into inflammation-related immunomodulatory activities.Formula:C28H33ClN2O5S2Color and Shape:SolidMolecular weight:577.16G108
CAS:G108 is an inhibitor of human cGAS and is used in the study of autoimmune diseases associated with human cGAS.Formula:C16H14Cl2N4O2Purity:99.13% - 99.75%Color and Shape:SolidMolecular weight:365.21NOD1-IN-1
CAS:NOD1/2-IN-1 (Compound 2) is a potent inhibitor of RIPK2 with an IC50 value of 0.65 nM as determined by the ADP-Glo assay. It selectively inhibits the NOD1 pathway, with an IC50 of 33 nM, effectively blocking the production of pro-inflammatory cytokines and thereby reducing inflammatory responses. This compound has potential applications in the research of colitis.Formula:C16H14ClN3O3Color and Shape:SolidMolecular weight:331.75COX-2-IN-9
COX-2-IN-9: potent oral COX-2 blocker, selective over Celecoxib, IC50 10.17 μM, less ulcers, strong anti-inflammatory.Formula:C25H23N5O4S2Color and Shape:SolidMolecular weight:521.61α-Gracinoic acid
CAS:α-Gracinoic acid acts as an inhibitor of mPGES-1, exhibiting anti-inflammatory properties.Formula:C29H42O4Color and Shape:SolidMolecular weight:454.64
