Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(142 products)
- CXCR(159 products)
- Cell wall(5 products)
- IL Receptor(110 products)
- IκB/IKK(58 products)
- LTR(3 products)
- MALT(25 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(425 products)
- NOD(21 products)
- NOS(61 products)
- Nrf2(82 products)
- PGE Synthase(31 products)
- ROS(70 products)
- TGF-beta/Smad(63 products)
- TLR(73 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
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Found 3389 products of "Immunology and Inflammation"
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TLR7 agonist 28
CAS:TLR7 agonist28 (compound 3) is a potent TLR7 agonist. This compound can be combined with anti-tumor monoclonal antibodies (mAb) for use in cancer immunotherapy.Formula:C26H25N9O7Color and Shape:SolidMolecular weight:575.533mPGES1-IN-5
CAS:mPGES1-IN-5 (compound 18) is a multi-substituted pyrimidine compound that acts as a submicromolar inhibitor of PGE2 production. It primarily exerts its anti-inflammatory effects by inhibiting mPGES-1 and demonstrates significant inhibitory activity in vivo against acute inflammation models.Formula:C27H27N3OColor and Shape:SolidMolecular weight:409.52TMV-IN-8
CAS:TMV-IN-8 (compound 7d) is an anti-tobacco mosaic virus (TMV) agent with an antiviral EC50 of 157.6 μg/mL. TMV-IN-8 blocks the assembly of TMV by binding with coat protein (Kd = 0.7 μM) and suppresses TMV coat protein gene expression and biosynthesis process [1].Formula:C26H22N6O4Color and Shape:SolidMolecular weight:482.49WK692
CAS:Compound WK692 (compund WK692) is a BCL6 inhibitor that effectively suppresses the growth of diffuse large B-cell lymphoma cells without toxic side effects and acts synergistically with inhibitors of EZH2 and PRMT5.Formula:C26H28Br2N8O5Color and Shape:SolidMolecular weight:692.36ASP-8731
CAS:ASP8731 is a selective inhibitor of BACH1 that prevents inflammation and vascular occlusion, and induces fetal hemoglobin in sickle cell disease.Formula:C20H21N5O4Color and Shape:SolidMolecular weight:395.41CD73-IN-12
CD73-IN-12, a compound from CN114437038A, shows strong anti-tumor activity by effectively inhibiting CD73 enzyme.Formula:C17H14F2N4O2Color and Shape:SolidMolecular weight:344.32Methoxyurea
CAS:Methoxyurea (Compound 3) is a potential modulator of nitric oxide (NO) donors, interacting with hemoglobin forms such as oxyhemoglobin (OxyHb) and methemoglobin (MetHb). It holds promise for use in research on sickle cell disease (SCD).Formula:C2H6N2O2Color and Shape:SolidMolecular weight:90.081COX-2/NO-IN-1
COX-2/NO-IN-1: oral iNOS & NO blocker (IC50=3.52μM), COX-2 supressor, anti-inflammatory, protects kidneys.Formula:C15H15NO3Color and Shape:SolidMolecular weight:257.28iNOs-IN-1
iNOs-IN-1 (YPW) is a strong iNOS inhibitor with dose-dependent anti-inflammatory properties, reducing IL-6, iNOS, and NO levels.Formula:C25H30N4O5Color and Shape:SolidMolecular weight:466.53FAPI-74
CAS:FAPI-74 is a PET (positron emission tomography) tracer involved in early FAPI-PET imaging.FAPI-74 can be used to study cancer tumors and degenerative diseases.
Formula:C36H49N9O8Color and Shape:SolidMolecular weight:735.83NDT-30805
NDT-30805, a triazolopyridine, blocks IL-1β in PBMC (IC50: 0.013μM) & NLRP3 inflammasome, for inflammation research.Formula:C23H22N6SColor and Shape:SolidMolecular weight:414.53SLC7A11-IN-2
CAS:SLC7A11-IN-2 (Compound 1) is an inhibitor of SLC7A11/xCT. It disrupts the oxidative balance in HeLa cells by decreasing intracellular glutathione levels and increasing oxidative stress, thereby inducing cell death with an IC50 of 10.23 μM. Molecular dynamics simulations have demonstrated that SLC7A11-IN-2 exhibits a stronger binding affinity to SLC7A11 compared to Erastin. This compound is useful for research in the field of cervical cancer.Formula:C19H24N4O3Color and Shape:SolidMolecular weight:356.42Keap1-Nrf2-IN-5
CAS:Keap1-Nrf2-IN-5 is a potent inhibitor of Keap1-Nrf2 PPI (Keap1-Nrf2 protein-protein interaction) (IC50: 4.1 μM, Kd: 3.7 μM).Formula:C23H30N4O6SColor and Shape:SolidMolecular weight:490.57Hypoxystat
CAS:Hypoxystat increases the affinity of hemoglobin for oxygen, thereby reducing the release of oxygen to tissues and inducing tissue hypoxia. [Hypoxystat] can alleviate mitochondrial disorder Leigh syndrome in Ndufs4 gene knockout mouse models. Hypoxystat is orally active.Formula:C21H21NO5Color and Shape:SolidMolecular weight:367.395BMY-25551
CAS:BMY-25551, a Mitomycin A analog, exhibits cytotoxicity 8 to 20 times greater than Mitomycin C against both murine and human tumor cell lines. It is applicable in research pertaining to cancer and hematological disorders.Formula:C17H21N3O7Color and Shape:SolidMolecular weight:379.36PB01
CAS:PB01 is a DPP-4 inhibitor with an IC50 of 15.66 nM. It effectively suppresses high glucose-induced ROS generation and mitochondrial superoxide production while significantly reducing the cellular expression of DPP-4. Additionally, PB01 notably lowers blood glucose levels in diabetic mice. It demonstrates excellent safety, exhibiting almost no cytotoxicity at a concentration of 100 μM. PB01 holds promise for research in the diabetes field.Formula:C18H21N5O3Color and Shape:SolidMolecular weight:355.391A-9758
CAS:A-9758: RORγt selective inverse agonist, IC50 5nM, inhibits IL-17A, Th17, and treats psoriasis.Formula:C25H23Cl2F3N2O3Purity:98%Color and Shape:SolidMolecular weight:527.36(R)-Ketoprofen
CAS:(R)-Ketoprofen is a non-steroidal anti-inflammatory drug (NSAID) that exhibits oral activity and analgesic properties. Unlike its counterpart, (R)-Ketoprofen does not significantly enhance the increase of inflammatory cytokines (such as Tumor Necrosis Factor (TNF) and Interleukin-1 (IL-1)) induced by LPS. However, it can inhibit the anti-inflammatory activity of (S)-Ketoprofen.Formula:C16H14O3Color and Shape:SolidMolecular weight:254.28VS-15
CAS:VS-15 is a selective inhibitor of IDO1, specifically binding to its apo-heme form. Additionally, VS-15 serves as an inhibitor of iNOS.Formula:C29H27N5O3Color and Shape:SolidMolecular weight:493.56NLRP3-IN-53
CAS:NLRP3-IN-53 (compound 1) is an NLRP3 inhibitor with an IC50 of 3.4nM.Formula:C22H27N5O4Color and Shape:SolidMolecular weight:425.48
