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Immunology and Inflammation

Immunology and Inflammation

Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.

Subcategories of "Immunology and Inflammation"

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Found 3035 products of "Immunology and Inflammation"

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  • CymitQuimica logo
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    Anticonvulsant agent 10

    <p>Anticonvulsant agent 10 (Compound 6d) is an inhibitor targeting the Keap1-Nrf2 interaction, with a strong activity showing an ED50 of 0.04 mmol/kg. By inhibiting the Keap1-Nrf2 binding, it activates the Nrf2/ARE pathway, providing anticonvulsant and neuroprotective effects, making it useful for research in epilepsy and neuroprotection.</p>
    Color and Shape:Odour Solid

    Ref: TM-T206426

  • KYN-101
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    KYN-101

    CAS:
    <p>KYN-101 is an and aryl hydrocarbon receptor (AHR) inhibitor with anticancer activity. KYN-101 is used for the study of breast cancer and acute myeloid leukemia.</p>
    Formula:C22H19FN6
    Purity:98.35%
    Color and Shape:Solid
    Molecular weight:386.43

    Ref: TM-T72056

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    3-(2-Hydroxyethyl) thio withaferin A

    <p>3-(2-Hydroxyethyl) thio withaferin A, a steroidal lactone, blocks NF-kB, targets vimentin, and inhibits EPCR shedding.</p>
    Formula:C30H44O7S
    Color and Shape:Solid
    Molecular weight:548.73

    Ref: TM-T75491

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    MTvkPABC-P5

    <p>MTvkPABC-P5d, functioning as a TLR7 agonist, serves as an immune stimulant and is utilized in the synthesis of immune-stimulating antibody conjugates (ISACs) [1</p>
    Formula:C52H73N11O14
    Color and Shape:Solid
    Molecular weight:1076.2

    Ref: TM-T79877

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    AB-680 ammonium

    <p>AB-680: potent, reversible CD73 inhibitor, Ki=4.9 pM, &gt;10,000-fold selectivity vs CD39, anti-tumor.</p>
    Formula:C20H30ClFN6O9P2
    Color and Shape:Solid
    Molecular weight:614.89

    Ref: TM-T73886

  • PROTAC IRAK4 degrader-4
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    PROTAC IRAK4 degrader-4

    CAS:
    <p>PROTAC IRAK4 degrader-4 is a targeted Cereblon-based molecule for degrading IRAK4.</p>
    Formula:C41H38F3N11O10
    Color and Shape:Solid
    Molecular weight:901.817

    Ref: TM-T39901

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    FGT-4

    <p>FGT-4 is a chimeric molecule targeting folate receptor β (FR-β) and functions as a TLR7 agonist. It enhances the secretion of iNOS and the pro-inflammatory cytokine IL-6 associated with M1 macrophages and promotes the proliferation of cytotoxic CD8+ T cells. FGT-4 demonstrates antitumor activity in the 4T1 breast cancer mouse model and is applicable for cancer immunotherapy research.</p>
    Formula:C50H57N11O9S2
    Color and Shape:Solid
    Molecular weight:1019.37821

    Ref: TM-T207417

  • β-Interleukin II (44-56)
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    β-Interleukin II (44-56)

    <p>β-Interleukin II is a peptide with the sequence NH2-ILE-LEU-ASN-GLY-ILE-ASN-ASN-TYR-LYS-ASN-PRO-LYS-LEU-COOH.</p>
    Formula:C68H113N19O19
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1500.74

    Ref: TM-TP2178

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    PSB-24000

    <p>PSB-24000 (Compound 27) is a selective ecto-5'-nucleotidase (CD73) inhibitor with a Ki value of 563 nM for inhibiting human CD73, and a Ki of 481 nM in membrane-bound CD73 in triple-negative breast cancer cells. It disrupts CD73’s recognition and action on substrate AMP, preventing AMP-induced immunosuppressive and pro-cancer adenosine production. PSB-24000 is promising for cancer research.</p>
    Color and Shape:Odour Solid

    Ref: TM-T206762

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    Lintuzumab

    CAS:
    <p>Lintuzumab (HuM-195) is an uncoupled humanized mouse monoclonal antibody against CD33 with anti-leukemic activity.</p>
    Purity:98% (SDS-PAGE); 98.6% (SEC-HPLC) - 98.1% (SDS-PAGE); 98.2% (SEC-HPLC)
    Color and Shape:Liquid

    Ref: TM-T9901A-065

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    CD73-IN-17

    <p>CD73-IN-17 (compound 19) is an inhibitor of CD73 with an IC50 of 0.1 μM against hCD73. It is applicable in cancer research.</p>
    Color and Shape:Odour Solid

    Ref: TM-T200431

  • 2-Aminoquinoline
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    2-Aminoquinoline

    CAS:
    <p>Compound Fr16621, with CAS No. 580-22-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr16621 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>
    Formula:C9H8N2
    Color and Shape:Light Yellow Crystals
    Molecular weight:144.18

    Ref: TM-Fr16621

  • EG01377 2HCl
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    EG01377 2HCl

    CAS:
    <p>EG01377 2HCl is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1) with a Kd value of 1.32 μM and an IC50 value of 609 nM for both EG01377</p>
    Formula:C26H32Cl2N6O6S2
    Purity:98.91%
    Color and Shape:Soild
    Molecular weight:659.6

    Ref: TM-T11154L

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    CD19 CAR circRNA

    <p>CD19 CAR circRNA expresses a CD19 car protein for CAR-T immunotherapy targeting B-cell antigens.</p>
    Color and Shape:Solid

    Ref: TM-T75104

  • NLRP3-IN-12
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    NLRP3-IN-12

    <p>NLRP3-IN-12 inhibits NLRP3 inflammasome, curbing IL-1β release with 0.45 μM IC50, for inflammatory bowel disease research.</p>
    Formula:C27H32ClNO7
    Color and Shape:Solid
    Molecular weight:518

    Ref: TM-T73034

  • PROTAC IRAK4 degrader-2
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    PROTAC IRAK4 degrader-2

    CAS:
    <p>PROTAC IRAK4 degrader-2 reduces IRAK4 in PBMCs with a DC50 of 36 nM and inhibits cytokines.</p>
    Formula:C57H68FN11O8S
    Color and Shape:Solid
    Molecular weight:1086.28

    Ref: TM-T74062

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    STING-IN-12

    <p>STING-IN-12 (compound Y2) acts as an inhibitor of STING. It suppresses IFNβ gene expression induced by SR717 with an IC50 of 0.75 μM. Additionally, STING-IN-12 inhibits STING pathway activation induced by the STING agonist SR717 in THP1 cells and by MSA-2 in mice.</p>
    Color and Shape:Odour Solid

    Ref: TM-T206291

  • Valeriandoid F
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    Valeriandoid F

    CAS:
    <p>Valeriandoid F, an iridoid, strongly inhibits NO production (IC50: 0.88 μM) and has anti-inflammatory, antiproliferative effects.</p>
    Formula:C23H34O9
    Color and Shape:Solid
    Molecular weight:454.516

    Ref: TM-T38891

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    Romilkimab

    CAS:
    <p>Romilkimab (SAR156597) is a chimeric humanized immunoglobulin (Ig) antibody designed to specifically target interleukins 4 and 13 (IL-4 and IL-13) [1].</p>
    Color and Shape:Liquid

    Ref: TM-T80610

  • HNGF6A
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    HNGF6A

    CAS:
    <p>increases glucose stimulated insulin secretion and glucose metabolism</p>
    Formula:C112H198N34O31S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2581.11

    Ref: TM-TP2258