Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(136 products)
- CXCR(147 products)
- Cell wall(5 products)
- IL Receptor(113 products)
- IκB/IKK(61 products)
- LTR(3 products)
- MALT(23 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(445 products)
- NOD(17 products)
- NOS(63 products)
- Nrf2(78 products)
- PGE Synthase(31 products)
- ROS(69 products)
- TGF-beta/Smad(58 products)
- TLR(66 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
Show 11 more subcategories
Found 3035 products of "Immunology and Inflammation"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Biotin-labeled ODN 1585 sodium
<p>Biotin-labeled ODN 1585 (sodium) serves as a potent inducer of IFN and TNFα production and facilitates the assessment of CpG ODN cellular uptake and</p>Color and Shape:Odour SolidNLRP3-IN-51
<p>NLRP3-IN-51 (Compound 3q) is an effective activator of the cholinergic anti-inflammatory pathway (CAP). This compound demonstrates potential for treating gouty arthritis as it inhibits the production of IL-1β in THP-1 cells induced by monosodium urate (MSU). Furthermore, NLRP3-IN-51 suppresses the phosphorylation of NF-κBp65 triggered by MSU without impacting the self-cleavage and activation of NLRP3, pro-caspase 1, or the second messenger caspase-1. Therefore, the initial stage of NLRP3 inhibition by NLRP3-IN-51 occurs through the activation of CAP.</p>Color and Shape:Odour SolidMCI
<p>MCI, a chemical compound demonstrating significant anti-inflammatory effects, particularly in collagen-induced arthritis (CIA) models, modulates inflammation</p>Formula:C45H52ClN7O13Purity:98%Color and Shape:SolidMolecular weight:934.39STING agonist-28
CAS:<p>STING agonist-28 (CF510), a non-nucleotide, boosts STING, TBK1, IRF3 phosphorylation, and cytokines; active against SARS-CoV.</p>Formula:C39H46N14O6Color and Shape:SolidMolecular weight:806.87TLQP-21
CAS:<p>TLQP 21, a VGF-derived peptide, guards CGCs against apoptosis and combats early diet-induced diabetes by boosting energy spend.</p>Formula:C107H170N40O26Purity:98%Color and Shape:SolidMolecular weight:2432.75MUC5AC motif peptide
<p>MUC5AC motif peptide is a 16-amino acid fragment of mucin 5.</p>Formula:C63H104N16O26Purity:98%Color and Shape:SolidMolecular weight:1501.62STING agonist-29
CAS:<p>CF511: non-nucleotide, small-molecule STING activator; fights SARS-CoV variants.</p>Formula:C38H44N14O6Color and Shape:SolidMolecular weight:792.85PNT2001
CAS:<p>PNT2001 (LY4181530) is an effective prostate-specific membrane antigen (PSMA) ligand with an IC50 of 3.1 nM. It enhances cellular internalization and, when labeled with 177Lu and 225Ac, is applicable for prostate cancer research.</p>Formula:C85H107N15O32Color and Shape:SolidMolecular weight:1850.84PMX 205
CAS:<p>PMX 205 is an effective complement antagonist of the C5a receptor.</p>Formula:C45H62N10O6Purity:98%Color and Shape:SolidMolecular weight:839.04Sacituzumab MMAE
<p>Sacituzumab-MMAE (CHB295) Anti-TROP2 Reference Antibody is produced in CHO cells and consists of a huIgG1 heavy chain and a hukappa light chain. This compound has a predicted molecular weight (MW) of 146.06 kDa.</p>Color and Shape:LiquidMolecular weight:150 kDaHNW005
<p>HNW005 is a dual inhibitor targeting the NLRP3 inflammasome and urate transporter 1 (URAT1). It exhibits an inhibition constant (KD) of 204.6 nM and an IC50 of 1.7 μM for NLRP3 inflammasome activation, while demonstrating an IC50 of 6.4 μM for inhibiting uric acid transmembrane transport. At an administered dose of 2 mg/kg in vivo, HNW005 achieves a uric acid reduction rate of 64.8%, effectively providing anti-inflammatory, analgesic, and urate-lowering effects by inhibiting NLRP3 inflammasome activation and uric acid transport. HNW005 is applicable for research in gouty arthritis.</p>Color and Shape:Odour SolidInbakicept
CAS:<p>Inbakicept (ALT 803) is a fusion protein of the IL-15 receptor 伪-sushi binding domain IL-15R伪Su and immunoglobulin G1 (human Fc fragment).</p>Purity:98.94%Color and Shape:LiquidKTX-951
CAS:<p>KTX-951, a PROTAC, degrades IRAK4 (DC50=18 nM), 22% oral bioavailability in rats, shows promise as anticancer agent.</p>Formula:C46H52F2N8O6Color and Shape:SolidMolecular weight:850.95BAY-069
CAS:<p>BAY-069 blocks BCAT1 (IC50:31 nM) & BCAT2 (IC50:153 nM), useful for cancer research.</p>Formula:C22H14ClF3N2O3Purity:99.58%Color and Shape:SoildMolecular weight:446.81Huangjiangsu A
CAS:<p>Huangjiangsu A, from D. villosa, may protect the liver from H2O2 damage and reduce ROS, showing therapeutic promise.</p>Formula:C51H82O22Purity:98%Color and Shape:SolidMolecular weight:1047.18Licoagrochalcone C
CAS:<p>Licoagrochalcone C, a flavonoid, inhibits NF-κB and NO production effectively.</p>Formula:C21H22O5Color and Shape:SolidMolecular weight:354.4Ubletamig
CAS:<p>Ubletamig is a humanized IgG4κ monoclonal antibody that targets MUC16.</p>Color and Shape:LiquidTLR8 agonist 2
CAS:<p>TLR8 agonist 2 activates human TLR8 (EC50=3nM), less effective on TLR7 (EC50=33.33μM).</p>Formula:C16H22N8Color and Shape:SolidMolecular weight:326.408BTH1704
<p>BTH1704 is a human monoclonal antibody targeting MUC1. It facilitates the killing of iC3b-opsonized tumor cells by leukocytes triggered by PGG. BTH1704 is applicable in studies on pancreatic cancer and breast cancer.</p>Color and Shape:Odour LiquidAllyl methyl trisulfide
CAS:<p>Allyl methyl trisulfide: a garlic oil compound with antibacterial, antioxidant, and antitumor properties.</p>Formula:C4H8S3Color and Shape:SolidMolecular weight:152.3
