Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(136 products)
- CXCR(148 products)
- Cell wall(5 products)
- IL Receptor(112 products)
- IκB/IKK(60 products)
- LTR(3 products)
- MALT(23 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(444 products)
- NOD(17 products)
- NOS(63 products)
- Nrf2(78 products)
- PGE Synthase(31 products)
- ROS(69 products)
- TGF-beta/Smad(58 products)
- TLR(66 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
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Found 3044 products of "Immunology and Inflammation"
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CD19 CAR circRNA
<p>CD19 CAR circRNA expresses a CD19 car protein for CAR-T immunotherapy targeting B-cell antigens.</p>Color and Shape:SolidRomurtide
CAS:<p>Romurtide is a synthetic muramyl dipeptide analog and can be used for the prophylaxis of leukocytopenia during radiation therapy.</p>Formula:C43H78N6O13Purity:98%Color and Shape:SolidMolecular weight:887.126Diplacol
CAS:<p>Diplacol, a geranylated flavanone isolated from Paulownia trees (Paulownia coreana UYEKI), exhibits anti-inflammatory properties by inhibiting NO production in LPS-stimulated Raw264.7 cells with an IC50 value of 4.53 μM [1].</p>Formula:C25H28O7Color and Shape:SolidMolecular weight:440.49NVP-DKY709
CAS:<p>NVP-DKY709 is a potent IKZF2 inhibitor for the treatment of cancers.</p>Formula:C25H27N3O3Purity:99%Color and Shape:SolidMolecular weight:417.55(S),15(S)-DiHETE
CAS:<p>5(S),15(S)-DiHETE, made by 15-LO from 5(S)-HETE, boosts human PMNL degranulation via PAF, not fMLP/A23187/LTB4, and lures eosinophils at ED50 of 0.3μM.</p>Formula:C20H32O4Color and Shape:SolidMolecular weight:336.472Pascolizumab
CAS:<p>Pascolizumab (SB-240683) is a humanized monoclonal antibody against IL-4. Pascolizumab has asthmatic effects and can be used to study allergic rhinitis.</p>Purity:> 95%Color and Shape:LiquidMolecular weight:147.18 kDaAra-F-NAD+
CAS:<p>Ara-F-NAD+, an arabino analogue of NAD + , is a potent, slow-binding CD38 NADase inhibitor, with a K i of 169 nM.</p>Formula:C21H26FN7O13P2Color and Shape:SolidMolecular weight:665.421Basiliximab
CAS:<p>Basiliximab: chimeric IgG1 antibody inhibiting interleukin-2 receptor, used for kidney transplant immunosuppression.</p>Purity:SDS-PAGE:94.1%;SEC-HPLC:95.3%Color and Shape:LiquidMolecular weight:144.01 kDaCyclo(L-Pro-L-Val)
CAS:<p>Cyclo(L-Pro-L-Val), from Mycobacterium spp., has anti-inflammatory effects, hinders phytopathogens, and suppresses IKKα, NF-κB, iNOS, and COX-2 activation.</p>Formula:C10H16N2O2Purity:98.18%Color and Shape:SolidMolecular weight:196.253-(2-Hydroxyethyl) thio withaferin A
<p>3-(2-Hydroxyethyl) thio withaferin A, a steroidal lactone, blocks NF-kB, targets vimentin, and inhibits EPCR shedding.</p>Formula:C30H44O7SColor and Shape:SolidMolecular weight:548.73CDD-3290
<p>CDD-3290 (Compound 20) is an inhibitor of prostate-specific antigen (PSA) with a Ki value of 216 nM. This compound also exhibits inhibitory effects on α-chymotrypsin and elastase.</p>Color and Shape:Odour SolidOATD-02 hydrochloride
<p>OATD-02 hydrochloride is the hydrochloride salt form of OATD-02. It is an orally effective, competitive, reversible, and non-covalent dual inhibitor of Arginase1 and Arginase2. OATD-02 hydrochloride serves as a sustained-release inhibitor that efficiently blocks the activity of intracellular arginases, with IC50 values of 20 nM (hARG1), 39 nM (hARG2), 39 nM (mARG1), and 28 nM (rARG1). It effectively eliminates tumor-induced immunosuppression caused by both types of arginases. This compound is utilized in research studies on melanoma.</p>Color and Shape:Odour SolidGalectin-8-IN-2
CAS:<p>Galectin-8-IN-2 (Compound 10) acts as an inhibitor of galectin-8N [1].</p>Formula:C15H20O7Color and Shape:SolidMolecular weight:312.32Guselkumab
CAS:<p>Guselkumab (CNTO 1959) is a recombinant human IgG1 monoclonal antibody targeting the IL-23p19 subunit.</p>Purity:SDS-PAGE:95% SEC-HPLC:98.97%Color and Shape:LiquidMolecular weight:144.8 kDaNT-0249
CAS:<p>NT-0249 is an inflammatory vesicle NLRP3 inhibitor with anti-inflammatory activity that reverses high-fat diet-induced obesity.</p>Formula:C22H28N5NaO4SPurity:98.11%Color and Shape:SoildMolecular weight:481.54Histone Modification Compound Library
<p>A unique collection of xnum histone modification related compounds for high throughput screening (HTS) and high content screening (HCS);</p>Color and Shape:Odour SolidBuChE-IN-20
<p>BuChE-IN-20 is a selective hBuChE inhibitor (IC50= 0.13 μM) with the ability to cross the blood-brain barrier (BBB). This compound, a derivative of L-Tryptophan, exhibits neuroprotective effects by inhibiting nitric oxide (NO) production and reducing reactive oxygen species (ROS) levels. It effectively suppresses the self-aggregation of amyloid-beta (Aβ) peptides and is applicable in Alzheimer's disease research.</p>Color and Shape:Odour SolidNF-κB-IN-9
<p>NF-κB-IN-9, a nuclear factor kappa B (NF-κB) targeting sonosensitizer with excitation and emission wavelengths (λex/λem) of 489/628 nm, features dual</p>Formula:C62H50N4O4SColor and Shape:SolidMolecular weight:947.15Tri(TLR4-IN-C34-C2-amide-PEG1)-amide-C3-COOH
<p>Tri(TLR4-IN-C34-C2-amide-PEG1)-amide-C3-COOH, a linker with TLR4-IN-C34, reduces inflammation in mice.</p>Formula:C78H125N7O36Color and Shape:SolidMolecular weight:1736.85PROTAC STING degrader-4
<p>PROTACSTING degrader-4 is a covalent STINGPROTAC degrader free of nitro groups, exhibiting a DC50 of 3.23 μM. It effectively inhibits STING and its downstream signaling pathways, including p-TBK1 and p-NF-κB (p-P65), as well as immune-inflammatory cytokines. Additionally, PROTACSTING degrader-4 mitigates renal and blood inflammation in mouse models of Cisplatin-induced acute kidney injury (AKI).</p>Formula:C39H42Cl2N8O9Color and Shape:SolidMolecular weight:836.24518
