Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(136 products)
- CXCR(148 products)
- Cell wall(5 products)
- IL Receptor(112 products)
- IκB/IKK(60 products)
- LTR(3 products)
- MALT(23 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(444 products)
- NOD(17 products)
- NOS(63 products)
- Nrf2(78 products)
- PGE Synthase(31 products)
- ROS(69 products)
- TGF-beta/Smad(58 products)
- TLR(66 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
Show 11 more subcategories
Found 3044 products of "Immunology and Inflammation"
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Histone Modification Compound Library
<p>A unique collection of xnum histone modification related compounds for high throughput screening (HTS) and high content screening (HCS);</p>Color and Shape:Odour Solid19-epi-Scholaricine
CAS:<p>19-epi-Scholaricine: indole alkaloid, taken orally, reduces collagen fibrosis, boosts SOD.</p>Formula:C20H24N2O4Color and Shape:SolidMolecular weight:356.42BuChE-IN-20
<p>BuChE-IN-20 is a selective hBuChE inhibitor (IC50= 0.13 μM) with the ability to cross the blood-brain barrier (BBB). This compound, a derivative of L-Tryptophan, exhibits neuroprotective effects by inhibiting nitric oxide (NO) production and reducing reactive oxygen species (ROS) levels. It effectively suppresses the self-aggregation of amyloid-beta (Aβ) peptides and is applicable in Alzheimer's disease research.</p>Color and Shape:Odour SolidEritoran
CAS:<p>Eritoran: TLR4 antagonist; shields mice from lethal influenza, EBOV, MARV; reduces granulocytosis, eases cytokine storm.</p>Formula:C66H126N2O19P2Color and Shape:SolidMolecular weight:1313.66BCL6 PROTAC 1
CAS:<p>BCL6 PROTAC 1: Selective BCL6 degrader, IC50 8.8 µM, used in DLBCL research.</p>Formula:C45H52ClN9O12Color and Shape:SolidMolecular weight:946.4(6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosahexaenoyl-CoA
CAS:<p>(6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosahexaenoyl-CoA ((6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosahexaenoyl-coenzyme A) acts as an NLRX1 modulator. This compound shows potential for research into immune and metabolism-related diseases.</p>Formula:C45H70N7O17P3SColor and Shape:SolidMolecular weight:1106.06Tri(TLR4-IN-C34-C2-amide-PEG1)-amide-C3-COOH
<p>Tri(TLR4-IN-C34-C2-amide-PEG1)-amide-C3-COOH, a linker with TLR4-IN-C34, reduces inflammation in mice.</p>Formula:C78H125N7O36Color and Shape:SolidMolecular weight:1736.85STING agonist-24
CAS:<p>CF504: non-nucleotide STING agonist, boosts STING, TBK1, IRF3 phosphorylation; raises IFN-β, IL-6, CXCL-10, TNF-α; active against SARS-CoV strains.</p>Formula:C34H37N13O5Color and Shape:SolidMolecular weight:707.74Amaroswerin
CAS:<p>Amaroswerin, a secoiridoid glucoside, has anti-inflammatory, antidiabetic, and other medicinal properties; it inhibits NO release at IC50 of 5.42 μg/mL.</p>Formula:C29H30O14Color and Shape:SolidMolecular weight:602.54Keap1-Nrf2-IN-25
<p>Keap1-Nrf2-IN-25 (Compound 19) is a potent Keap1-Nrf2 inhibitor with an IC50 of 0.55 μM and exhibits a Keap1 binding affinity (Kd of 0.50 μM). This compound activates Nrf2, reducing reactive oxygen species (ROS) and pro-inflammatory cytokines (IL-1β, IL-6). Additionally, Keap1-Nrf2-IN-25 provides protective effects against DSS-induced colitis.</p>Formula:C25H28N2O6SColor and Shape:SolidMolecular weight:484.565Itolizumab
CAS:<p>Itolizumab (Anti-Human CD6 Recombinant Antibody) is a recombinant anti-CD6 monoclonal antibody that humanizes the extracellular SRCR distal domain 1 of CD6.</p>Purity:> 95%Color and Shape:LiquidMolecular weight:144.82 kDaAChE-IN-82
<p>AChE-IN-82 (compound 49) is an acetylcholinesterase (AChE) inhibitor. It inhibits eeAChE, eqBChE, hMAO-A, hMAO-B, and BACE-1 with IC50 values of 0.072, 9.81, 14.52, 0.024, and 2.42 μM, respectively. Additionally, AChE-IN-82 inhibits COX-1, COX-2, and 5-LOX with IC50 values of 60.41, 0.187, and 0.18 μM, respectively. The compound also demonstrates strong neuroprotective effects by significantly reducing H2O2-induced oxidative stress.</p>Formula:C21H18N4O5S2Color and Shape:SolidMolecular weight:470.52Pascolizumab
CAS:<p>Pascolizumab (SB-240683) is a humanized monoclonal antibody against IL-4. Pascolizumab has asthmatic effects and can be used to study allergic rhinitis.</p>Purity:> 95%Color and Shape:LiquidMolecular weight:147.18 kDaNrf2/HO-1 activator 3
<p>Nrf2/HO-1 Activator 3 (Compound C3a) is an activator of the Nrf2 signaling pathway that facilitates the translocation of Nrf2 into the nucleus and enhances the expression of heme oxygenase-1 (HO-1). In H9c2 cardiomyocytes subjected to H2O2 or high glucose stimulation, Nrf2/HO-1 Activator 3 inhibits the excessive expression of ROS and MDA, suppressing cell viability and colony formation, thereby exhibiting antioxidant activity.</p>Formula:C27H26N2O6Color and Shape:SolidMolecular weight:474.51PS 1145 dihydrochloride
CAS:<p>IκB kinase (IKK) inhibitor</p>Formula:C17H13Cl3N4OPurity:98%Color and Shape:SolidMolecular weight:395.67C12-rrw-NH2
<p>C12-rrw-NH2 (Compound Lip7) is an antimicrobial agent effective against Gram-positive bacteria, particularly demonstrating significant activity against Methicillin-resistant Staphylococcus aureus (MRSA). It induces bacterial cell death by depolarizing the bacterial cell membrane, disrupting membrane integrity, causing nucleic acid and protein leakage, and promoting the generation of Reactive Oxygen Species (ROS). C12-rrw-NH2 is applicable in research focused on developing highly stable antimicrobial peptides.</p>Formula:C35H58N10O5Color and Shape:SolidMolecular weight:698.9Clivatuzumab
CAS:<p>Clivatuzumab is a humanized anti-myxinomab, which can target the MUC1 epitope highly expressed on the surface of most pancreatic cancer cells, and has a good</p>Purity:SDS-PAGE:95% SEC-HPLC:99.99%Color and Shape:LiquidMolecular weight:145.42 kDaCOX-2-IN-52
<p>COX-2-IN-52 (Compound 5l) is an orally active and selective COX-2 inhibitor with an IC50 of 54 nM. It can suppress the release of NO in cells, exhibiting anti-inflammatory properties. COX-2-IN-52 offers high gastrointestinal safety and is suitable for research on oral anti-inflammatory drugs.</p>Formula:C16H13IN4O4S2Color and Shape:SolidMolecular weight:516.333N188 TFA
<p>N188 TFA is a radiolabeled ligand based on a bicyclic peptide scaffold, targeting the protein nectin-4, which is overexpressed in various tumors. It can be efficiently labeled with the radioactive isotope 68Ga to form 68Ga-N188, suitable for positron emission tomography (PET) imaging. The development of N188 TFA and its radiolabeled form, 68Ga-N188, holds potential for the diagnosis and treatment of cancers such as urothelial carcinoma.</p>Color and Shape:Odour SolidBiotin-labeled ODN 2395 sodium
<p>Biotin-labeled ODN 2395 (sodium), a Class C oligodeoxynucleotide and TLR9 agonist, serves to assess cellular uptake and localization of CpG ODN through a biotin</p>Color and Shape:Odour Solid
