Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(136 products)
- CXCR(148 products)
- Cell wall(5 products)
- IL Receptor(112 products)
- IκB/IKK(60 products)
- LTR(3 products)
- MALT(23 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(444 products)
- NOD(17 products)
- NOS(63 products)
- Nrf2(78 products)
- PGE Synthase(31 products)
- ROS(69 products)
- TGF-beta/Smad(58 products)
- TLR(66 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
Show 11 more subcategories
Found 3044 products of "Immunology and Inflammation"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Nurulimab
CAS:<p>Nurulimab (BCD-145) is an anti-CTLA-4 antibody with anti-cancer activity for the study of skin and musculoskeletal diseases.</p>Purity:95.5% (SDS-PAGE); 97.3% (SEC-HPLC) - 95.5% (SDS-PAGE); 97.3% (SEC-HPLC)Color and Shape:LiquidBRCA2-IN-1
<p>BRCA2-IN-1 (Compound 3j) is a potential BRCA2 inhibitor with antiproliferative activity against the breast cancer MCF-7 cell line. This compound also demonstrates DPPH radical scavenging ability, with an IC50 value of 12.36 µM.</p>Color and Shape:Odour SolidNuclear Receptor Compound Library
<p>A unique collection of 531 nuclear receptor signaling targeted compounds for high throughput and high content screening;</p>Color and Shape:Odour SolidIFN-γ Antagonist 1
CAS:<p>IFN-γ Antagonist 1 (AYCRDGKIGPPKLDIRKEEKQI), an interferon γ (IFN γ) antagonist, effectively inhibits IFN-γ induced HLR/DR antigen expression in Colon 205 cells</p>Formula:C115H194N34O34SColor and Shape:SolidMolecular weight:2629.04(±)11(12)-EET
CAS:<p>(±)11(12)-EET is a fully racemic version of the R/S enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes.[1][2][3[]A higher</p>Formula:C20H32O3Color and Shape:SolidMolecular weight:320.47Kinase Inhibitor Library
<p>A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;</p>Color and Shape:Odour SolidSMRT peptide
CAS:SMRT peptide, one of the corepressor factors interacting with the BCL6 BTB domain, binds to the BTB domain of BCL6 to enhance its transcriptional repression function. Additionally, SMRT peptide is utilized for studying protein-protein interactions.Formula:C82H142N26O24Color and Shape:SolidMolecular weight:1876.16Arginase inhibitor 7
CAS:<p>Arginase Inhibitor 7 (compound A17), an inhibitor of arginase (ARG1), exhibits an IC 50 value of 0.16 μM and possesses high oral bioavailability [1].</p>Formula:C14H29BN6O5Color and Shape:SolidMolecular weight:372.23Ladanetin-6-O-β-D-glucopyranoside
CAS:<p>Ladanetin-6-O-β-D-glucopyranoside, an active flavonoid, exhibits antioxidative effects and has potential for research into cardioprotective effects [1].</p>Formula:C22H22O11Color and Shape:SolidMolecular weight:462.4TGF-β/Smad Compound Library
<p>A unique collection of xnum TGF-beta/Smad signaling targeted compounds for high throughput and high content screening;</p>Color and Shape:Odour Solid2-(Phosphonooxy)benzoic acid
CAS:<p>2-(Phosphonooxy)benzoic acid (Fosfosal), used as the anti-inflammatory agent, has the anti-bacterial effect.</p>Formula:C7H7O6PPurity:99.83%Color and Shape:SolidMolecular weight:218.1Pam3CSK4-Biotin
CAS:<p>Pam3CSK4-Biotin is a biotinylated derivative of Pam3CSK4, functioning as a Toll-like receptor 1/2 (TLR1/2) agonist.</p>Formula:C103H192N14O17S2Purity:98%Color and Shape:SolidMolecular weight:1962.85Keap1-Nrf2-IN-9
CAS:<p>Keap1-Nrf2-IN-9 inhibits Keap1-Nrf2 PPI with 0.575 µM IC50, boosts Nrf2 genes, non-toxic in ARPE19 cells.</p>Formula:C31H30N2O11S2Color and Shape:SolidMolecular weight:670.71Antiparasitic agent-26
<p>Antiparasitic agent-26 (Compound 8) is an antiparasitic compound that effectively inhibits the growth of Naegleria fowleri, with an IC50 of 22.87 μM (trophozoite stage) and 25.16 μM (cyst stage). It exerts its antiparasitic effects by inducing programmed cell death, which includes cytosolic calcium accumulation, mitochondrial membrane potential collapse, ATP synthesis inhibition, ROS accumulation, and chromatin condensation. Antiparasitic agent-26 can be utilized in research on primary amoebic meningoencephalitis (PAM).</p>Color and Shape:Odour SolidXJB-5-131
CAS:<p>XJB-5-131: synthetic, bi-functional antioxidant; targets mitochondria, scavenges ROS/electrons, protects CB MNCs from irradiation.</p>Formula:C53H80N7O9Color and Shape:SolidMolecular weight:959.263CD73-IN-16
<p>CD73-IN-16 (compound 18) acts as an inhibitor of hCD73, exhibiting an IC50 value of 0.28 μM.</p>Color and Shape:Odour SolidN(G)-Nitroarginine-4-nitroanilide
CAS:<p>N(G)-Nitroarginine-4-nitroanilide is an anti-nociceptive in mice.</p>Formula:C12H17N7O5Purity:98%Color and Shape:SolidMolecular weight:339.31Antibacterial agent 119
<p>Antibacterialagent 119 (Compound 21 g) is a potential antibacterial agent effective against methicillin-resistant Staphylococcus aureus, with a minimum inhibitory concentration (MIC) of less than 1 μg/mL against tested strains. It induces reactive oxygen species (ROS) generation and disrupts bacterial cell membranes, causing their rupture. Antibacterialagent 119 exhibits strong antimicrobial activity, low cytotoxicity, rapid bactericidal action, and favorable in vivo antibacterial efficacy.</p>Formula:C42H54BrClN2O4Color and Shape:SolidMolecular weight:766.246β-Amyrin acetate
CAS:<p>Beta-Amyrin acetate: HMGCR & sEH inhibitor (IC50 3.4 μM), anti-inflammatory, antifungal, antioxidant, anti-hyperlipidemic.</p>Formula:C32H52O2Purity:99.87%Color and Shape:SolidMolecular weight:468.75FITC-labeled ODN 1018 sodium
<p>FITC-labeled ODN 1018 (sodium), a TLR-9 agonist oligodeoxynucleotide, facilitates the assessment of CpG ODN cellular uptake and localization through confocal</p>Color and Shape:SolidMolecular weight:8171FITC-labeled ODN 1585 sodium
<p>FITC-labeled ODN 1585 (sodium) effectively induces IFN and TNFα production and serves to assess CpG ODN cellular uptake and localization through confocal laser-</p>Color and Shape:Odour SolidAntifungal agent 123
<p>Antifungalagent 123 (Compound 4b) demonstrates strong affinity for the oxidoreductase of Staphylococcus aureus or membrane proteins of Candida albicans, exhibiting both antibacterial and antifungal properties. Additionally, it is capable of scavenging free radicals, showcasing antioxidant effects. Antifungalagent 123 also inhibits the TLR signaling pathway and possesses anti-inflammatory activity.</p>Formula:C21H20N4O3Color and Shape:SolidMolecular weight:376.409KTX-951
CAS:<p>KTX-951, a PROTAC, degrades IRAK4 (DC50=18 nM), 22% oral bioavailability in rats, shows promise as anticancer agent.</p>Formula:C46H52F2N8O6Color and Shape:SolidMolecular weight:850.95BTH1704
<p>BTH1704 is a human monoclonal antibody targeting MUC1. It facilitates the killing of iC3b-opsonized tumor cells by leukocytes triggered by PGG. BTH1704 is applicable in studies on pancreatic cancer and breast cancer.</p>Color and Shape:Odour LiquidiE-DAP dihydrochloride
<p>iE-DAP dihydrochloride is a Nod1 agonist that activates the NF-κB pathway through recognition by Nod1, leading to an inflammatory cytokine response. This compound is useful for studying maternal-fetal inflammation and preterm birth.</p>Formula:C12H23Cl2N3O7Color and Shape:SolidMolecular weight:391.09131CD19 CAR mRNA
<p>CD19 CAR mRNA expresses a protein for use in CAR-CD19 T cell therapy, targeting B cell antigen for cancer treatment.</p>Color and Shape:SolidStemRegenin 1 Hydrochloride
CAS:<p>StemRegenin 1 Hydrochloride is an AhR antagonist (IC₅₀ = 127 nM) that inhibits RANKL-induced osteoclast generation and differentiation.</p>Formula:C24H24ClN5OSPurity:99.94%Color and Shape:SolidMolecular weight:466FITC-labeled ODN 2088 sodium
<p>FITC-labeled ODN 2088 (sodium) serves as a potent inhibitor of TLR3, TLR7, and TLR9, and is utilized to assess CpG ODN cellular uptake and localization</p>Color and Shape:Odour Solid1-Hydroxy-ibuprofen
CAS:<p>1-Hydroxy Ibuprofen, a metabolite in P. australis, targets COX-1/COX-2 with IC50s: 13 μM/370 μM.</p>Formula:C13H18O3Color and Shape:SolidMolecular weight:222.2802Allyl methyl trisulfide
CAS:<p>Allyl methyl trisulfide: a garlic oil compound with antibacterial, antioxidant, and antitumor properties.</p>Formula:C4H8S3Color and Shape:SolidMolecular weight:152.3Anti-Human MSLN Antibody (Clone HN1)
<p>Anti-Human MSLN Antibody (Clone HN1) is a humanised monoclonal antibody targeting MSLN (Mesothelin), , blocks the interaction between MSLN and CA125, cancer .</p>Purity:95%Color and Shape:Odour LiquidPolyinosinic acid
CAS:<p>Polyinosinic acid: single-strand, TLR3 agonist, boosts immune response, has immune regulation uses.</p>Formula:(C10H13N4O8P)xColor and Shape:SolidMifamurtide sodium
CAS:<p>Mifamurtide sodium is a drug against osteosarcoma, a kind of bone cancer mainly affecting children and young adults. It was approved in Europe in March 2009.</p>Formula:C59H108N6NaO19PPurity:98%Color and Shape:SolidMolecular weight:1259.48TSR-033
CAS:<p>TSR-033 is a human IgG4 antibody with high affinity for LAG-3 (lymphocyte activation gene-3), a co-receptor linked to diminished T cell activity, frequently co-</p>Color and Shape:LiquidKYN-101
CAS:<p>KYN-101 is an and aryl hydrocarbon receptor (AHR) inhibitor with anticancer activity. KYN-101 is used for the study of breast cancer and acute myeloid leukemia.</p>Formula:C22H19FN6Purity:98.35%Color and Shape:SolidMolecular weight:386.43Inbakicept
CAS:<p>Inbakicept (ALT 803) is a fusion protein of the IL-15 receptor 伪-sushi binding domain IL-15R伪Su and immunoglobulin G1 (human Fc fragment).</p>Purity:98.94%Color and Shape:LiquidcGAMP disodium
CAS:<p>cGAMP disodium, a bacterial CDN, boosts interferon production and activates STING, enhancing immune responses as a sublingual adjuvant.</p>Formula:C20H24N10O13P2·2NaColor and Shape:SoildMolecular weight:720.39E7766 diammonium salt
CAS:<p>E7766 diammonium salt, a macrocycle-bridged STING agonist, exhibits a dissociation constant (Kd) of 40 nM, demonstrating potent pan-genotypic and antitumor</p>Formula:C24H32F2N12O8P2S2Color and Shape:SolidMolecular weight:780.66Phytoene desaturase-IN-1
CAS:<p>Potent PDS inhibitor with Kd of 65.9 μM, induces mRNA reduction and ROS accumulation, useful in agriculture.</p>Formula:C18H13ClF3N3O2SColor and Shape:SolidMolecular weight:427.83Biotin-labeled ODN 1585 sodium
<p>Biotin-labeled ODN 1585 (sodium) serves as a potent inducer of IFN and TNFα production and facilitates the assessment of CpG ODN cellular uptake and</p>Color and Shape:Odour SolidValeriandoid F
CAS:<p>Valeriandoid F, an iridoid, strongly inhibits NO production (IC50: 0.88 μM) and has anti-inflammatory, antiproliferative effects.</p>Formula:C23H34O9Color and Shape:SolidMolecular weight:454.516PNT2001
CAS:<p>PNT2001 (LY4181530) is an effective prostate-specific membrane antigen (PSMA) ligand with an IC50 of 3.1 nM. It enhances cellular internalization and, when labeled with 177Lu and 225Ac, is applicable for prostate cancer research.</p>Formula:C85H107N15O32Color and Shape:SolidMolecular weight:1850.84Feeblin
CAS:<p>Feeblin (IRF5-IN-1) induces protein degradation, inhibits pro-inflammatory pathways, and is used for autoimmune disease research.</p>Formula:C27H33N3O2Purity:99.58% - 99.88%Color and Shape:SoildMolecular weight:431.57Inflexuside B
CAS:<p>Inflexuside B, an abietane diterpenoid derived from the aerial parts of Isodon inflexus, effectively inhibits lipopolysaccharide (LPS)-activated NO Synthase in</p>Formula:C35H48O11Color and Shape:SolidMolecular weight:644.75COX-2/15-LOX-IN-2
<p>COX-2/15-LOX-IN-2 is a potent inhibitor of both COX-2 and 15-LOX, demonstrating IC50 values of 0.065 μM for COX-2 and 1.86 μM for 15-LOX.</p>Formula:C27H26N6OS2Purity:98%Color and Shape:SolidMolecular weight:514.66AB-680 ammonium
<p>AB-680: potent, reversible CD73 inhibitor, Ki=4.9 pM, >10,000-fold selectivity vs CD39, anti-tumor.</p>Formula:C20H30ClFN6O9P2Color and Shape:SolidMolecular weight:614.89STING agonist-25
CAS:<p>STING agonist-25 is a non-nucleotide that activates STING, enhances immune response, and is active against SARS-CoV strains.</p>Formula:C36H41N13O6Color and Shape:SolidMolecular weight:751.79PROTAC STING Degrader-1
CAS:<p>PROTAC STING Degrader-1 (Compound SP23) is a STING-targeted PROTAC degrader exhibiting a DC50 of 3.2 μM and demonstrates anti-inflammatory activity [1].</p>Formula:C34H33N7O10Color and Shape:SolidMolecular weight:699.67NF-κΒ activator 1
CAS:<p>NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.</p>Formula:C16H11FN2O2SPurity:99.58%Color and Shape:SolidMolecular weight:314.33Cbl-b-IN-28
<p>Cbl-b-IN-28 (Compound B2) is an orally active Cbl-b inhibitor. It enhances the function of immune cells by promoting the secretion of cytokines like IL-2 and modulating the phosphorylation levels of key proteins in the T cell receptor signaling pathway. Cbl-b-IN-28 is applicable in cancer immunology research.</p>Color and Shape:Odour Solid
