Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(136 products)
- CXCR(148 products)
- Cell wall(5 products)
- IL Receptor(112 products)
- IκB/IKK(60 products)
- LTR(3 products)
- MALT(23 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(444 products)
- NOD(17 products)
- NOS(63 products)
- Nrf2(78 products)
- PGE Synthase(31 products)
- ROS(69 products)
- TGF-beta/Smad(58 products)
- TLR(66 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
Show 11 more subcategories
Found 3044 products of "Immunology and Inflammation"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
NBD peptide
CAS:<p>NBD peptide inhibits the NF-κB signaling pathway by preventing the binding of the NEMO-IKK complex. It exhibits anti-inflammatory activity by blocking the production of pro-inflammatory cytokines. Additionally, NBD peptide demonstrates immunosuppressive effects through the regulation of immune cells. It enhances transmembrane capacity by conjugating with the cell-penetrating peptide HIV-TAT.</p>Formula:C62H88N14O20Color and Shape:SolidMolecular weight:1349.44STING agonist-28
CAS:<p>STING agonist-28 (CF510), a non-nucleotide, boosts STING, TBK1, IRF3 phosphorylation, and cytokines; active against SARS-CoV.</p>Formula:C39H46N14O6Color and Shape:SolidMolecular weight:806.87RGB097
<p>RGB097 is an efficacious inhibitor of D-dopachrome tautomerase (D-DT), with an IC50 value of 0.5 µM. It holds potential for applications in cancer research.</p>Formula:C26H22F3N5O3Molecular weight:509.16747CTT2274
<p>CTT2274 is a prodrug of MMAE. It consists of a prostate-specific membrane antigen (PSMA) binding scaffold, a biphenyl motif, a pH-sensitive phosphoramidate linker, and an MMAE payload. CTT2274 selectively targets and binds to PSMA to deliver MMAE and has the capability to inhibit prostate cancer.</p>Formula:C119H159N17O33P2Color and Shape:SolidMolecular weight:2417.58Complement C1s-IN-1
CAS:<p>Complement C1s-IN-1 is a selective inhibitor of complement C1s，oral and brain penetrable, inhibit human serum-induced formation of membrane attack complexes</p>Formula:C22H20F2N6OPurity:97.77%Color and Shape:SoildMolecular weight:422.43Corza6
<p>Corza6 is a potent and selective peptide inhibitor of the human voltage-gated proton channel (hHv1). It binds to the external voltage sensor domain (VSD) loop in hHv1 at a resting membrane potential (RMP) of natural hyperpolarization in mammalian cells with a Kd of approximately 1 nM. Corza6 facilitates sperm capacitation and permits sustained production of reactive oxygen species (ROS) in leukocytes (WBC).</p>Formula:C203H293N55O61S7Color and Shape:SolidMolecular weight:4704.29KRN7000 analog 1
<p>KRN7000 analog 1 stimulates a strong Th1-biased immune response by inducing interferon-γ (IFN-γ) and reducing interleukin-4 (IL-4). This compound shows potential as an antitumor agent and vaccine adjuvant.</p>Formula:C47H76FNO9SMolecular weight:849.52248Antifungal agent 123
<p>Antifungalagent 123 (Compound 4b) demonstrates strong affinity for the oxidoreductase of Staphylococcus aureus or membrane proteins of Candida albicans, exhibiting both antibacterial and antifungal properties. Additionally, it is capable of scavenging free radicals, showcasing antioxidant effects. Antifungalagent 123 also inhibits the TLR signaling pathway and possesses anti-inflammatory activity.</p>Formula:C21H20N4O3Color and Shape:SolidMolecular weight:376.409Clivatuzumab
CAS:<p>Clivatuzumab is a humanized anti-myxinomab, which can target the MUC1 epitope highly expressed on the surface of most pancreatic cancer cells, and has a good</p>Purity:SDS-PAGE:95% SEC-HPLC:99.99%Color and Shape:LiquidMolecular weight:145.42 kDaEritoran
CAS:<p>Eritoran: TLR4 antagonist; shields mice from lethal influenza, EBOV, MARV; reduces granulocytosis, eases cytokine storm.</p>Formula:C66H126N2O19P2Color and Shape:SolidMolecular weight:1313.66cGAMP diammonium
<p>cGAMP is a second messenger that triggers interferon production via STING activation upon detecting cytosolic DNA.</p>Formula:C20H30N12O13P2Color and Shape:SolidMolecular weight:708.47Reltecimod
CAS:Reltecimod, a CD28 antigen inhibitor, is used potentially for the treatment of necrotizing soft tissue infection.Formula:C46H72N10O15SPurity:98%Color and Shape:SolidMolecular weight:1037.19Biotin-labeled ODN 2395 sodium
<p>Biotin-labeled ODN 2395 (sodium), a Class C oligodeoxynucleotide and TLR9 agonist, serves to assess cellular uptake and localization of CpG ODN through a biotin</p>Color and Shape:Odour SolidAra-F-NAD+
CAS:<p>Ara-F-NAD+, an arabino analogue of NAD + , is a potent, slow-binding CD38 NADase inhibitor, with a K i of 169 nM.</p>Formula:C21H26FN7O13P2Color and Shape:SolidMolecular weight:665.421PROTAC IRAK4 degrader-2
CAS:<p>PROTAC IRAK4 degrader-2 reduces IRAK4 in PBMCs with a DC50 of 36 nM and inhibits cytokines.</p>Formula:C57H68FN11O8SColor and Shape:SolidMolecular weight:1086.28PSMA-IN-1
<p>PSMA-IN-1 (compound 23) is an inhibitor of PSMA with a Ki value of 2.49 nM. It inhibits tumor growth with high selectivity and specificity in PSMA+ tumor models. Additionally, PSMA-IN-1 serves as an NIR (λEX: 620 nm; λEM: 670 nm) dye for tumor imaging. PSMA-IN-1 is utilized in prostate cancer research.</p>Formula:C66H80N10O20Molecular weight:1332.55504Cafestol palmitate
CAS:<p>Cafestol palmitate is an active compound found in green coffee beans. It can enhance the activity of glutathione S-transferase (GST) in mice and also exhibits weak COX-2 inhibitory activity.</p>Formula:C36H58O4Color and Shape:SolidMolecular weight:554.843AM-103 Free Acid
CAS:<p>AM-103 Free Acid is a bio-active chemical.</p>Formula:C36H39N3O4SColor and Shape:SolidMolecular weight:609.78Ibritumomab
<p>Ibritumomab is a murine-derived anti-CD20 monoclonal antibody that kills tumor cells by forming free radicals in target cells and surrounding tissues.</p>Purity:96% (SDS-PAGE); 95.9% (SEC-HPLC) - 96% (SDS-PAGE); 95.9% (SEC-HPLC)Color and Shape:Odour LiquidModakafusp alfa
CAS:<p>Modakafusp alfa (TAK-573): Humanized anti-CD38 monoclonal antibody with IFNα2b for multiple myeloma research.</p>Color and Shape:LiquidPMX 205
CAS:<p>PMX 205 is an effective complement antagonist of the C5a receptor.</p>Formula:C45H62N10O6Purity:98%Color and Shape:SolidMolecular weight:839.04Keap1-Nrf2-IN-9
CAS:<p>Keap1-Nrf2-IN-9 inhibits Keap1-Nrf2 PPI with 0.575 µM IC50, boosts Nrf2 genes, non-toxic in ARPE19 cells.</p>Formula:C31H30N2O11S2Color and Shape:SolidMolecular weight:670.71Anti-inflammatory agent 88
<p>Anti-inflammatory agent 88 (compound 6) is a carbazole derivative found in marine Streptomyces with anti-inflammatory properties. It exerts its effects by inhibiting pro-inflammatory factors and enhancing the expression of anti-inflammatory factors within the Myd88/Nf-κB pathway. This compound holds potential for the development of anti-inflammatory drugs.</p>Formula:C13H10BrNO2Molecular weight:290.98949BCL6 PROTAC 1
CAS:<p>BCL6 PROTAC 1: Selective BCL6 degrader, IC50 8.8 µM, used in DLBCL research.</p>Formula:C45H52ClN9O12Color and Shape:SolidMolecular weight:946.43-(3-Methoxyphenyl)acrylic acid
CAS:<p>3-(3-Methoxyphenyl)acrylic acid can inhibit free radical generation, has antioxidant potential, and can be used in biochemical experiments and drug synthesis.</p>Formula:C10H10O3Purity:99.91%Color and Shape:SolidMolecular weight:178.19CD19 CAR mRNA
<p>CD19 CAR mRNA expresses a protein for use in CAR-CD19 T cell therapy, targeting B cell antigen for cancer treatment.</p>Color and Shape:SolidTMV-IN-7
<p>TMV-IN-7 (compound G2) is a potent inhibitor of Tobacco Mosaic Virus (TMV). It exhibits strong hydrophobic interactions that prevent the virus from self-assembling.</p>Formula:C17H15ClN6OSMolecular weight:386.07166Antibacterial agent 273
<p>Antibacterialagent 273 (Compound 15e) is an antimicrobial agent targeting bacterial cell membranes, effectively disrupting them with a MIC value of 4 μg/mL against Staphylococcus aureus. It causes the leakage of intracellular nucleic acids and proteins, inhibits bacterial metabolic activity, and induces the accumulation of reactive oxygen species (ROS) within bacteria. Antibacterialagent 273 is applicable in research on infections caused by Staphylococcus aureus.</p>Color and Shape:Odour SolidSARS-CoV-2-IN-107
<p>SARS-CoV-2-IN-107 (Compound A7) is an inhibitor of SARS-CoV-2 3CLpro, with an IC50 of 261.3 nM. It inhibits the replication of SARS-CoV-2, exhibiting an EC50 of 11.7 μM. Additionally, SARS-CoV-2-IN-107 demonstrates anti-inflammatory activity in LPS-stimulated RAW264.7 macrophages, with a NO inhibition rate of 68.6%.</p>Formula:C15H11FO4Color and Shape:SolidMolecular weight:274.244FAPI-46
CAS:<p>FAPI-46 is a radiotracer for fibroblast activation protein (FAP),conjugated with 68Ga or 177Lu tracer for FAP tumours in positron emission tomography (PET).</p>Formula:C41H57F2N11O9Color and Shape:SolidMolecular weight:885.96RDR03785
CAS:<p>The MIF Antagonist IV, RDR 03785 controls the biological activity of MIF. This small molecule/inhibitor is primarily used for Cell Structure applications.</p>Formula:C19H18F3NO4Purity:98.92%Color and Shape:SolidMolecular weight:381.35LAG-3 cyclic peptide inhibitor 12
<p>LAG-3cyclic peptide inhibitor 12 (Cyclic peptide 12) is an inhibitor of LAG-3, exhibiting an IC50 of 4.45 μM and a Ki of 2.66 µM.</p>Formula:C44H67N13O11S3Color and Shape:SolidMolecular weight:1050.28ARC186
<p>ARC186 is a highly potent aptamer that serves as a complement inhibitor by blocking the convertase-catalyzed activation of C5.</p>Color and Shape:SolidMolecular weight:120702.76Tri(TLR4-IN-C34-PEG2-amide-PEG1)-amide-C3-COOH
<p>Tri(TLR4-IN-C34-PEG2/PEG1)-amide-C3-COOH is a TLR4 inhibiting linker, reducing inflammation in endotoxemia and enterocolitis mouse models.</p>Formula:C78H125N7O42Color and Shape:SolidMolecular weight:1832.85Ac-macropa
<p>Ac-macropa is a conjugate of Actinium-225 that targets PSMA, and it is useful for researching prostate cancer.</p>Formula:C39H52AcN6O9SMolecular weight:1007.379412-Oxo phytodienoic acid
CAS:<p>12-oxo PDA boosts alkaloid production in E. californica, enhances B. dioica tendril curls, and blocks JA-induced cell death in A. fru mutants.</p>Formula:C18H28O3Purity:98%Color and Shape:SolidMolecular weight:292.41Amaroswerin
CAS:<p>Amaroswerin, a secoiridoid glucoside, has anti-inflammatory, antidiabetic, and other medicinal properties; it inhibits NO release at IC50 of 5.42 μg/mL.</p>Formula:C29H30O14Color and Shape:SolidMolecular weight:602.54Pratensein
CAS:<p>Pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells.</p>Formula:C16H12O6Purity:99.90%Color and Shape:SolidMolecular weight:300.263-Methoxycatechol
CAS:<p>3-Methoxycatechol: lignin-based, esophageal carcinogen. 1,2-Dihydroxy-3-methoxybenzene: potent anti-EMCV.</p>Formula:C7H8O3Purity:99.31%Color and Shape:SolidMolecular weight:140.14STING-IN-13
<p>STING-IN-13 is a selective STING inhibitor that effectively suppresses downstream signaling of the STING pathway and STING-mediated inflammation. It exhibits low toxicity and is suitable for research related to STING-associated inflammatory and autoimmune diseases.</p>Color and Shape:Odour SolidChitohexaose hexahydrochloride
CAS:<p>Chitohexaose hexahydrochloride, a TLR4-inhibiting chitosan derivative, blocks LPS-induced inflammation.</p>Formula:C36H74Cl6N6O25Color and Shape:SolidMolecular weight:1203.71Maritimetin
CAS:<p>Maritimein, an aurone from Coreopsis tinctoria, has potent antioxidant activity (IC50: 4.12 μM) and is used in cardiovascular research.</p>Formula:C15H10O6Color and Shape:SolidMolecular weight:286.24NH2-UAMC1110 TFA
CAS:<p>NH2-UAMC1110 TFA, a derivative of the fibroblast activation protein (FAP) inhibitor UAMC1110, serves as a precursor in the formation of FAPI-QS, a chelating</p>Formula:C23H24F5N5O5Purity:99.02%Color and Shape:SolidMolecular weight:545.46PROTAC IRAK4 degrader-6
CAS:<p>PROTAC IRAK4 degrader-6, potent, targets Cereblon to degrade IRAK4, detailed in US20190192668A1.</p>Formula:C42H41F3N12O8Color and Shape:SolidMolecular weight:898.861NLRP3-IN-35
<p>NLRP3-IN-35 (compound 11) is an NLRP3 inhibitor with an IC50 of less than 1 μM.</p>Formula:C26H25FN4O2Molecular weight:444.19615TMV-IN-6
<p>TMV-IN-6 (Compound 4g) serves as a novel antiviral and fungicidal agent that impedes tobacco mosaic virus (TMV) assembly, functioning by attachment to TMV coat</p>Formula:C29H27N3OSColor and Shape:SolidMolecular weight:465.614-methyl-6-phenyl-2H-pyranone
CAS:<p>4-methyl-6-phenyl-2H-pyranone from Scutellaria boosts mitochondria, shields astrocytes from peroxide.</p>Formula:C12H10O2Purity:>99.99%Color and Shape:SolidMolecular weight:186.21PROTAC IRAK4 degrader-1
CAS:<p>PROTAC IRAK4 degrader-1 is a Cereblon based PROTAC, PROTAC IRAK4 ligand-1, the E3 ligase ligand Pomalidomide and the PROTAC linker AM-Imidazole-PA-Boc.</p>Formula:C44H39F3N12O7Purity:99.76%Color and Shape:SolidMolecular weight:904.85PROTAC IRAK4 degrader-4
CAS:<p>PROTAC IRAK4 degrader-4 is a targeted Cereblon-based molecule for degrading IRAK4.</p>Formula:C41H38F3N11O10Color and Shape:SolidMolecular weight:901.817Melredableukin alfa
CAS:<p>Melredableukin alfa, a human IgG1-κ fused with IL2 mutein, is studied for autoimmune hepatitis and ulcerative colitis.</p>Color and Shape:Liquid
