Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(143 products)
- CXCR(158 products)
- Cell wall(5 products)
- IL Receptor(110 products)
- IκB/IKK(57 products)
- LTR(3 products)
- MALT(25 products)
- MRP(6 products)
- NADPH-oxidase(2 products)
- NF-κB(386 products)
- NOD(25 products)
- NOS(61 products)
- Nrf2(81 products)
- PGE Synthase(31 products)
- ROS(70 products)
- TGF-beta/Smad(60 products)
- TLR(74 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
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Found 3428 products of "Immunology and Inflammation"
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RS 09 TFA
RS 09 TFA is a TLR4 agonist and LPS peptide analogue, promotes NF-κB nuclear translocation, induces inflammatory cytokine secretion in RAW264.7 macrophages.
Formula:C33H50F3N9O11Purity:99.78%Color and Shape:SolidMolecular weight:805.8β-Interleukin II (44-56)
β-Interleukin II is a peptide with the sequence NH2-ILE-LEU-ASN-GLY-ILE-ASN-ASN-TYR-LYS-ASN-PRO-LYS-LEU-COOH.Formula:C68H113N19O19Purity:98%Color and Shape:SolidMolecular weight:1500.74POT-4 acetate
POT-4 acetate inhibits Complement C3 activation. POT-4 acetate can be used for studies about age-related macular degeneration.Formula:C74H106N22O20S2Purity:98%Color and Shape:SolidMolecular weight:1687.9Anti-inflammatory agent 36
CAS:Anti-inflammatory compound inhibits TNF-a/IL-6 in mouse macrophages; IC50=3.69/3.68uM.Formula:C25H27NO7Purity:99.85%Color and Shape:SoildMolecular weight:453.48Ref: TM-T64359
500mgTo inquire5mg48.00€1mL*10mM (DMSO)56.00€10mg75.00€25mg133.00€50mg208.00€100mg311.00€Corza6
Corza6 is a potent and selective peptide inhibitor of the human voltage-gated proton channel (hHv1). It binds to the external voltage sensor domain (VSD) loop in hHv1 at a resting membrane potential (RMP) of natural hyperpolarization in mammalian cells with a Kd of approximately 1 nM. Corza6 facilitates sperm capacitation and permits sustained production of reactive oxygen species (ROS) in leukocytes (WBC).Formula:C203H293N55O61S7Color and Shape:SolidMolecular weight:4704.29CBT-295
CBT-295, an orally active autotaxin (ATX) inhibitor, effectively decreases inflammatory cytokines including TGF-β, TNF-α, and IL-6, along with the bile duct proliferation marker CK-19, and ameliorates liver fibrosis. The compound's ability to reverse liver fibrosis contributes to lowered ammonia levels in the blood and brain, which in turn reduces ammonia-induced neuroinflammation. CBT-295 shows potential for the study of liver cirrhosis and related encephalopathy.Formula:C18H20ClN3OColor and Shape:SolidMolecular weight:329.826-Amyl-2-pyrone
CAS:6-Amyl-2-pyrone exhibits inhibitory activity against tyrosinase, antibacterial and antiviral activity against Penicillium vulpinum and Aspergillus flavus, and antifungal activity against Sclerotinia sp.Formula:C10H14O2Purity:99.00%Color and Shape:SolidMolecular weight:166.22TAN 420E
CAS:TAN 420E, a Streptomyces metabolite, scavenges radicals, reduces liver TBARS by 72%, and is antibacterial and cytotoxic to leukemia cells.Formula:C30H44N2O9Color and Shape:SolidMolecular weight:576.687sEH/FLAP-IN-1
sEH/FLAP-IN-1 (Compound 46A) serves as a dual inhibitor targeting both sEH and FLAP.Purity:98%Color and Shape:Odour SolidMik-β-1
Mik-Beta-1 is a human IgG1-kappa monoclonal antibody targeting IL2RB. For isotype control, refer to Human IgG1 kappa, Isotype Control. Mik-Beta-1 is applicable in research related to the prevention of allograft rejection.Color and Shape:Odour LiquidTemtokibart
CAS:Temtokibart is a humanized monoclonal antibody targeting IL22RA1, used in autoimmune and inflammatory disease research.Color and Shape:LiquidMolecular weight:142.34 kDa4-hydroperoxy 2-Nonenal
CAS:4-HNE, a marker of oxidative stress, arises from oxidized ω-6 fats like linoleic acid and shows cytotoxic and genotoxic effects.Formula:C9H16O3Color and Shape:SolidMolecular weight:172.224TLR7 agonist 27
TLR7 agonist27 (compound 24) is an effective TLR7 agonist with an EC50 of 238.1 nM. It exhibits weak agonistic activity towards NOD2 (nucleotide-binding oligomerization domain 2) with an EC50 of 6.2 μM. TLR7 agonist27 serves as a potent immunostimulant and can be utilized as a vaccine adjuvant and/or an immunotherapeutic agent.Formula:C47H64N10O11Color and Shape:SolidMolecular weight:945.07NOD2 agonist 3
NOD2agonist 3 (Compound 5) is an effective NOD2 agonist with an EC50 value of 111.45 nM, demonstrating immunoenhancing properties.Formula:C27H39N3O7Color and Shape:SolidMolecular weight:517.61R-HP210
R-HP210 blocks LPS-triggered IL-1β, IL-6, COX-2 gene transcription and has a 3.80 μM IC50 for NF-κB inhibition without activating GCs.Formula:C22H19N3O2S2Color and Shape:SolidMolecular weight:421.54BMS-986251
CAS:BMS-986251: Oral RORγt inverse agonist, EC50 12 nM; inhibits IL-17 (EC50 24 nM); effective in mouse psoriasis models.Formula:C30H29F8NO5SColor and Shape:SolidMolecular weight:667.61Somantadine
CAS:Somantadine has antiviral activities and can be used for research on preventing and treating coronavirus-related diseases.Formula:C14H25NPurity:99.9%Color and Shape:SolidMolecular weight:207.35Compstatin TFA
Compstatin TFA: 13-residue cyclic peptide, inhibits primate complement C3, species-specific, protease-resistant, IC50=63μM (classical), 12μM (alternative).Formula:C68H100F3N23O19S2Color and Shape:SolidMolecular weight:1664.79MEDI-7836
MEDI-7836 is a humanized monoclonal antibody inhibitor that targets the interleukin-13 (interleukin-13 receptor) receptor. It shows potential for research into diseases associated with inflammation.Color and Shape:Odour LiquidBCX 1470 hydrochloride
BCX 1470 hydrochloride is a serine protease inhibitor with anti-inflammatory activity that inhibits factor D hemolytic activity and may be used to study edema.Formula:C14H11ClN2O2S2Purity:99.71%Color and Shape:SoildMolecular weight:338.83NLRP3-IN-54
NLRP3-IN-54 (Compound C4) is an inhibitor of NLRP3. It effectively reduces the levels of active Caspase-1 and active IL-1β (IC50= 0.805 μM), making it useful for inflammation research.Formula:C21H15Br2ClN2O5SColor and Shape:SolidMolecular weight:602.68iE-DAP
CAS:iE-DAP is a biologically active peptide that functions as a NOD1 agonist.Formula:C12H21N3O7Purity:98%Color and Shape:SolidMolecular weight:319.31Anti-inflammatory agent 48
Anti-inflammatory agent 48 functions by inhibiting the NF-κB signaling pathway and activating HO-1 expression, characterizing its role as an anti-inflammatoryFormula:C24H21Cl2NO3Purity:98%Color and Shape:SolidMolecular weight:442.33Ara-F-NAD+ sodium
Ara-F-NAD+ sodium, an arabino analogue of NAD+, serves as a potent, reversible, and slow-binding inhibitor of the CD38 NADase [1] [2].Formula:C21H25FN7NaO13P2Color and Shape:SolidMolecular weight:687.44-Methylamino antipyrine hydrochloride
CAS:4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole.Formula:C12H16ClN3OPurity:98%Color and Shape:SolidMolecular weight:253.734'-hydroxy Flurbiprofen
CAS:4'-hydroxy Flurbiprofen can be used in related research in the field of life sciences. Its product number is T35722 and CAS number is 52807-12-2.Formula:C15H13FO3Color and Shape:SolidMolecular weight:260.264GBR-1342
GBR-1342 is a human bispecific antibody targeting CD38 and CD3. It inhibits the activity of cancer cell lines Daudi, RAJI, RPMI8226, IM-9, and NCI-H929, and is applicable to multiple myeloma research.Color and Shape:Odour LiquidTAB-004
TAB-004 is a human monoclonal antibody targeting MUC1. It specifically identifies the tMUC1 present in all major subtypes of breast cancer without affecting normal breast epithelial cells. Additionally, TAB-004 is applicable for research on triple-negative breast cancer (TNBC).Color and Shape:Odour LiquidAxinelline A
CAS:Axinelline A: COX inhibitor, IC50 of 2.22 μM (COX-2) & 8.89 μM (COX-1), anti-inflammatory.Formula:C12H15NO6Color and Shape:SolidMolecular weight:269.25SARS-CoV-2 Mpro-IN-41
SARS-CoV-2 Mpro-IN-41 (Compound 7e) is an orally active inhibitor targeting COX-2 and SARS-CoV-2 Mpro, with respective IC50 values of 9.66 μM and 13.24 μM. It also demonstrates inhibitory activity against COX-1 (IC50: 46.11 μM). This compound significantly suppresses the expression of inflammation-related cytokines such as TNF-α, IL-6, and IL-1β, exhibiting anti-inflammatory properties. By selectively inhibiting COX-2 and SARS-CoV-2 Mpro, SARS-CoV-2 Mpro-IN-41 exerts both anti-inflammatory and antiviral effects, making it a potential candidate for research in inflammation and COVID-19 treatment.Formula:C27H23ClN4O3SColor and Shape:SolidMolecular weight:518.11794MC1
MC1, an effective NLRP3 inhibitor, exhibits a KD value of 19.3 nM and is devoid of cytotoxicity. This compound enhances cognitive function without causing adverse effects and exhibits no hepatotoxicity. MC1 holds potential for research in Alzheimer's disease.Formula:C23H23N3O6S2Color and Shape:SolidMolecular weight:501.58Canakinumab
CAS:Canakinumab: Human IL-1β antibody, anti-inflammatory, treats gout & coronary disease, IC50 of 43.6 pM (human), 40.8 pM (monkey).
Purity:98.8%Color and Shape:LiquidMolecular weight:145.18 kDaBiotin-labeled Agatolimod sodium
Biotin-labeled Agatolimod (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of cellular uptake and localization ofColor and Shape:Odour SolidHNGF6A
CAS:increases glucose stimulated insulin secretion and glucose metabolismFormula:C112H198N34O31S2Purity:98%Color and Shape:SolidMolecular weight:2581.11Pemedolac
CAS:Pemedolac (Dexpemedolac) is a small molecule COX inhibitor used to treat neurological disorders, skin and musculoskeletal disorders.Formula:C22H23NO3Purity:99.7%Color and Shape:SolidMolecular weight:349.42Phthalazine
CAS:Compound PDK0135, with CAS No. 253-52-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0135 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C8H6N2Color and Shape:Yellow SolidMolecular weight:130.14Pegtarazimod
CAS:Pegtarazimod (RLS-0071) inhibits the complement system through both the classical and lectin pathways. It suppresses myeloperoxidase (MPO) activity, leading to reduced ROS production, and decreases the formation of neutrophil extracellular traps (NET). Pegtarazimod exhibits anti-inflammatory properties and is applicable in the study of acute graft-versus-host disease.Formula:C122H224N20O46S2Color and Shape:SolidMolecular weight:2771.32CAY10614
CAS:CAY10614 is a TLR4 antagonist.
Formula:C42H78INO2Color and Shape:SolidMolecular weight:755.995Huangjiangsu A
CAS:Huangjiangsu A, from D. villosa, may protect the liver from H2O2 damage and reduce ROS, showing therapeutic promise.Formula:C51H82O22Purity:98%Color and Shape:SolidMolecular weight:1047.18Methyl 3,4-Dihydroxyphenylacetate
CAS:Methyl 3,4-Dihydroxyphenylacetate is an effective enterovirus 71 (EV71) inhibitor, suppressing EV71 replication in rhabdomyosarcoma (RD) cells, antiviral.Formula:C9H10O4Purity:97.03%Color and Shape:SolidMolecular weight:182.17(Rac)-γ-Tocopherol
CAS:(Rac)-γ-Tocopherol (DMPBQ) is an isoform of Vitamin E that undergoes conversion to γ-Tocopherol through the action of tocopherol cyclase.Formula:C28H48O2Color and Shape:SolidMolecular weight:416.68Anti-inflammatory agent 93
Compound 2g (Anti-inflammatory agent 93) is an active compound that exhibits analgesic activity.Formula:C27H17Cl2N3O2Color and Shape:SolidMolecular weight:486.35Multinoside A
CAS:Multinoside A is a useful organic compound for research related to life sciences. The catalog number is T124593 and the CAS number is 59262-54-3.Formula:C27H30O16Color and Shape:SolidMolecular weight:610.521OVA Peptide (323-339)
CAS:OVA Peptide (323-339) is an immunodominant epitope peptide, MHC class II-restricted T-cell epitope , and a B-cell epitope that is recognized by IgE antibodies.Formula:C74H120N26O25Purity:99.38%Color and Shape:SolidMolecular weight:1773.9LL-37 GKE acetate
LL-37 GKE acetate, a peptide and active structural domain of LL-37, inhibits lps-induced vascular nitric oxide production,less toxic,antimicrobial，sepsis.Formula:C121H206N38O30Purity:99.88%Color and Shape:SolidMolecular weight:2673.17KD014
KD014 (DX-2400) is a human monoclonal antibody (mAb) that targets MMP14, with a Ki of 0.9 nM. It inhibits TGFβ and SMAD2/3 signaling, increases macrophage count and iNOS expression, and shifts macrophage phenotype towards an antitumor M1-like type. KD014 exhibits antitumor activity in three tumor models (MDA-MB-231, MDA-MB-435, and PC3) and is applicable in breast cancer research.Color and Shape:Odour LiquidApo A-I mimetic 5A peptide
Apo A-I mimetic 5A peptide is a synthetic peptide molecule designed based on the structure and function of naturally occurring apolipoprotein A-I (Apo A-I). It facilitates the efflux of cholesterol from inside cells, helping to reduce intracellular cholesterol accumulation. Additionally, Apo A-I mimetic 5A peptide exhibits anti-inflammatory properties, lowering inflammatory markers in blood and tissues. This peptide is used in cardiovascular disease research.Formula:C197H295N47O56Molecular weight:4215.16808ZL-1102
ZL-1102 is a humanized monoclonal antibody inhibitor targeting interleukin-17A (IL-17A). SCH-900117 is being investigated for its potential use in the treatment of autoimmune diseases such as psoriasis and rheumatoid arthritis.Color and Shape:Odour LiquidtLyP-1 peptide
CAS:tLyP-1 peptide is an NRP-1 targeting peptide with an IC50 of 4 μM, and its amino acid sequence is CGNKRTR. It can specifically bind to NRP-1 to target tumor cells.Formula:C31H59N15O10SColor and Shape:SolidMolecular weight:833.96Tricarbonyldichlororuthenium(II) dimer
CAS:Tricarbonyldichlororuthenium(II) dimer, CORM-2, CO-releasing anti-inflammatory. Affordable Excellence: Reliable Quality You Can TrustFormula:C6Cl4O6Ru2Color and Shape:SolidMolecular weight:512.01
