Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(136 products)
- CXCR(148 products)
- Cell wall(5 products)
- IL Receptor(112 products)
- IκB/IKK(60 products)
- LTR(3 products)
- MALT(23 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(444 products)
- NOD(17 products)
- NOS(63 products)
- Nrf2(79 products)
- PGE Synthase(31 products)
- ROS(69 products)
- TGF-beta/Smad(58 products)
- TLR(66 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
Show 11 more subcategories
Found 3045 products of "Immunology and Inflammation"
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COX-2/15-LOX-IN-1
CAS:<p>COX-2/15-LOX-IN-1 is a dual inhibitor for COX-2/15-LOX with anti-inflammatory properties (IC50: COX-1 10.65μM, COX-2 0.075μM, 15-LOX 2.98μM).</p>Formula:C21H21N7S3Color and Shape:SolidMolecular weight:467.63Ruzotolimod
CAS:<p>Ruzotolimod, an agonist of TLR7, exhibits promising potential for investigating HBV, COVID-19, and SARS-CoV-2 infections （WO2021130195A1）[1].</p>Formula:C14H18N4O5SColor and Shape:SolidMolecular weight:354.38Heterophdoid A
CAS:<p>Heterophdoid A is an anti-inflammatory agent that inhibits NO production in BV-2 cells (IC50: 5.93 μM).</p>Formula:C26H42O10Color and Shape:SolidMolecular weight:514.61MitoB
CAS:<p>MitoB is a novel exon of mitochondrial hydrogen peroxide.</p>Formula:C25H23BBrO2PColor and Shape:SolidMolecular weight:477.14IRAK4-IN-21
CAS:<p>IRAK4-IN-21: Oral IRAK4 inhibitor, IC50: IRAK4 5 nM, TAK1 56 nM; curbs IL-23, aids autoimmune research.</p>Formula:C28H28FN7O2Color and Shape:SolidMolecular weight:513.57MIND4-17
CAS:<p>MIND4-17 activates NRF2 by binding Keap1 C151, blocking Keap1-Nrf2, stabilizes Nrf2, and promotes its nuclear entry, with strong antioxidant effects.</p>Formula:C20H15N5O3SColor and Shape:SolidMolecular weight:405.43IKKβ-IN-1
CAS:<p>IKKβ-IN-1 is a potent, orally active inhibitor of IkappaB (IKK-β) (IC50: 0.20 μM).</p>Formula:C31H30N4O4SColor and Shape:SolidMolecular weight:554.66COX-2/5-LOX-IN-1
CAS:<p>COX-2/5-LOX-IN-1, a benzothiophen-2-yl pyrazole, inhibits COX-2 & 5-LOX with IC50: COX-1 (12.13μM), COX-2 (0.4μM), 5-LOX (4.96μM). Better than Celecoxib.</p>Formula:C14H10ClN3O4S2Color and Shape:SolidMolecular weight:383.83Insulin levels modulator
CAS:<p>Insulin level regulators can be used to treat diabetes.</p>Formula:C21H23N7OSPurity:98%Color and Shape:SolidMolecular weight:421.52MK-0703
CAS:<p>MK-0703 is a selective cyclooxygenase-2 inhibitor.</p>Formula:C17H22O5SPurity:98%Color and Shape:SolidMolecular weight:338.42MALT1-IN-3
CAS:<p>MALT1-IN-3 is a potent inhibitor of MALT1 protease (IC50: 0.06 μM) with IC50 values of 0.14 and 0.13 μM for human IL6 and IL10, respectively, in OCI-LY3 cells.</p>Formula:C21H19F3N8O2Color and Shape:SolidMolecular weight:472.42R110
CAS:<p>R110 shows the potential for cancer research that is a potent, competitive MIF2 tautomerase inhibitor (IC 50 = 15 μM) [1].</p>Formula:C15H17ClN2OSColor and Shape:SolidMolecular weight:308.837-NINA
CAS:<p>non-selective NOS inhibitor</p>Formula:C7H5N3NaO2Purity:98%Color and Shape:SolidMolecular weight:186.12Prostaglandin G/H synthase 1 inhibitor
CAS:<p>Prostaglandin G/H synthase 1 inhibitor (CP 74006) is a selective D5D inhibitor with an IC(50) value of 20 nM.</p>Formula:C13H11ClN2OPurity:99.76%Color and Shape:SolidMolecular weight:246.69iNOS-IN-2
CAS:<p>iNOS-IN-2 (Compound 53) is a potent inducible nitric oxide synthase (iNOS) protein down-regulator.</p>Formula:C25H31NO7Color and Shape:SolidMolecular weight:457.52Anti-inflammatory agent 8
CAS:<p>Anti-inflammatory agent 8 targets COX-2 over COX-1, IC50 of 0.09 nM, orally bioavailable.</p>Formula:C18H15N5OS2Color and Shape:SolidMolecular weight:381.47STING ligand-1
CAS:<p>STING ligand-1 is a lead STING ligand(IC50 of 68 nM for HAQ STING).</p>Formula:C29H27ClFNO5Purity:98%Color and Shape:SolidMolecular weight:523.98NBC 6
CAS:<p>NLRP3-IN-NBC6: potent NLRP3 inflammasome inhibitor, IC50 574 nM, Ca2+ independent, inhibits inflammasome in THP-1 cells/BMDMs.</p>Formula:C18H16BCl3N2O2Color and Shape:SolidMolecular weight:409.5YS-121
CAS:<p>YS121 inhibits mPGES-1 (IC50=3.4μM) & 5-LOX (IC50=6.5μM), and lowers PGE2 in A549 cells (EC50=12μM).</p>Formula:C20H26ClN3O2SColor and Shape:SolidMolecular weight:407.96UC-1V150
CAS:<p>UC-1V150: TLR7 agonist, triggers immune response, anti-tumor, precursor for ISAC synthesis.</p>Formula:C16H17N5O4Color and Shape:SolidMolecular weight:343.34CHS-111
CAS:<p>CHS-111 is a benzyl indazole that inhibits O2- generation, fMLP-induced PLD activity (IC50 3.9μM), and disrupts PLD1/Arf6 and RhoA interactions.</p>Formula:C21H18N2OPurity:98%Color and Shape:SolidMolecular weight:314.38IL-1β-IN-2
CAS:<p>IL-1β-IN-2, a cannabigerol derivative, serves as a potent inhibitor of IL-1β, exhibiting anti-inflammatory and pain-resolving properties [1].</p>Formula:C22H34O2Color and Shape:SolidMolecular weight:330.5MALT1-IN-8
CAS:<p>MALT1-IN-8: potent MALT1 inhibitor, IC50=2 nM; hinders OCI-LY3 cells, IC50=1.16 μM; anticancer, from patent WO2018165385A1.</p>Formula:C20H15Cl2N7OColor and Shape:SolidMolecular weight:440.29(-)-Ibuprofenamide
CAS:<p>(-)-Ibuprofenamide is an amide prodrug of Ibuprofen with anti-inflammatory activity.</p>Formula:C13H19NOPurity:98%Color and Shape:SolidMolecular weight:205.3Nrf2-Activator-12G
CAS:<p>Nrf2-Activator-12G is a potent Nrf-2 activator.</p>Formula:C15H13ClO3SPurity:98%Color and Shape:SolidMolecular weight:308.78Ppc-1
CAS:<p>Ppc-1 inhibits Porphyromonas gingivalis, uncouples mitochondria, and blocks IL-2, with anti-obesity, antibacterial, anti-inflammatory effects.</p>Formula:C21H25NO4Purity:98%Color and Shape:SolidMolecular weight:355.43Hetrombopag
CAS:<p>Hetrombopag: potent thrombopoietin receptor agonist, well tolerated, safe, promising for immune thrombocytopenia research.</p>Formula:C25H22N4O5Color and Shape:SolidMolecular weight:458.47COX-2-IN-14
CAS:<p>COX-2-IN-14 (2a) is a potent, selective COX-2 inhibitor with high affinity and notable anti-inflammatory effects in mice.</p>Formula:C18H18N4O6Color and Shape:SolidMolecular weight:386.364N-α-Tosyl-L-lysine chloromethyl ketone hydrochloride
CAS:<p>N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride inhibits trypsin-like proteases and IFN-γ activities.</p>Formula:C14H22Cl2N2O3SPurity:97.44%Color and Shape:PowderMolecular weight:369.31COX/5-LO-IN-1
CAS:<p>COX/5-LO-IN-1 is a cyclooxygenase and 5-lipoxygenase (5-LO) inhibitor, and used for inflammatory and allergic disease states.</p>Formula:C16H15FN2O2SPurity:98%Color and Shape:SolidMolecular weight:318.37Thiazolinobutazone
CAS:<p>Thiazolinobutazone is the 2-amino-2-thiazoline salt of phenylbutazone.</p>Formula:C22H26N4O2SColor and Shape:SolidMolecular weight:410.53NRP1 antagonist 2
CAS:<p>NRP1 antagonist 2 (Compound 1) is an NRP1 antagonist.</p>Formula:C20H17ClN6OS2Color and Shape:SolidMolecular weight:456.97TBK1/IKKε-IN-4
CAS:<p>TBK1/IKKε-IN-4, a 6-aminopyrazolopyrimidine derivative, serves as a potent, selective inhibitor for TBK1 and IKKε, demonstrating IC50 values of 13 nM and 59 nM</p>Formula:C28H35N7O4Color and Shape:SolidMolecular weight:533.62Tilarginine
CAS:<p>Tilarginine is a nitric oxide synthetase competitive inhibitor.</p>Formula:C7H16N4O2Purity:98%Color and Shape:SolidMolecular weight:188.23AHR antagonist 5
CAS:<p>Potent, oral AHR blocker from WO2018195397; IC50 < 0.5μM; hinders tumor growth with anti-PD-1.</p>Formula:C25H27Cl3FN7Purity:98%Color and Shape:SolidMolecular weight:550.89NLRP3 antagonist 1
CAS:<p>Potential cancer research drug, NLRP3 antagonist 1, targets immune response in macrophages, neutrophils.</p>Formula:C16H18N6OColor and Shape:SolidMolecular weight:310.35Phortress
CAS:<p>Phortress (NSC-710305) is a potent AhR ligand with strong binding affinity, which subsequently triggers the transcription of CYP1A1 and induces antitumor</p>Formula:C20H25Cl2FN4OSPurity:99.89%Color and Shape:SolidMolecular weight:459.41QD-394
CAS:<p>QD-394 promotes ROS, impairs GSH/GSSG ratio, and is cytotoxic to pancreatic cancer cells, with synergy with napabucasin.</p>Formula:C19H19N5O2Color and Shape:SolidMolecular weight:349.39COX-2-IN-16
CAS:<p>COX-2-IN-16: potent, selective oral COX-2 blocker, IC50=102 μM, reduces NO, anti-inflammatory.</p>Formula:C19H12BrN3O2Color and Shape:SolidMolecular weight:394.22(+)-DHMEQ
CAS:<p>(+)-DHMEQ is an antioxidant transcription factor Nrf2 activator. (+)-DHMEQ is the enantiomer of (-)-DHMEQ.</p>Formula:C13H11NO5Color and Shape:SolidMolecular weight:261.23STING Agonist 1a
CAS:<p>STING agonist 1a activates STING, induces IRF-SEAP, IFN-β, IL-6, CXCL10 (EC50=16.77 µM); effects reversed by STING KO/inhibitor H-151.</p>Formula:C19H11Cl2N5OColor and Shape:SolidMolecular weight:396.23PHA-408
CAS:<p>PHA-408 is a novel potent, highly selective and ATP-competitive inhibitor of IKB kinase-2.</p>Formula:C29H27ClFN7O2Purity:98%Color and Shape:SolidMolecular weight:560.02AN-3485
CAS:<p>AN-3485 is a Toll-Like Receptor(TLR) inhibitor (IC50s: 18 to 580 nM).</p>Formula:C14H13BClNO3Color and Shape:SolidMolecular weight:289.52Isoandrographolide
CAS:<p>Isoandrographolide induces cell differentiation, protects the liver, blocks NLRP3, and reduces silicosis in mice.</p>Formula:C20H30O5Color and Shape:SolidMolecular weight:350.45NOS-IN-3
CAS:<p>NOS-IN-3: potent, selective iNOS inhibitor; IC50 of 4.6 µM; spares eNOS; low toxicity; potential for septic shock treatment.</p>Formula:C10H15N3OColor and Shape:SolidMolecular weight:193.25Tyrosinase-IN-12
CAS:<p>Tyrosinase-IN-12(Non-competitive tyrosinase inhibitor) is a potent non-competitive tyrosinase inhibitor with an IC50 of 49.33 ± 2.64 µM and a Ki of 31.25 ± 0.25</p>Formula:C16H12ClN3SPurity:99.2%Color and Shape:SoildMolecular weight:313.8Cyclic-di-GMP diammonium
CAS:<p>C-di-GMP diammonium activates STING, regulates biofilms, motility, and virulence in bacteria.</p>Formula:C20H30N12O14P2Color and Shape:SolidMolecular weight:724.47Eltrombopag methyl ester
CAS:<p>Eltrombopag methyl ester, a Tpo receptor agonist derivative, boosts platelet production for thrombocytopenia research.</p>Formula:C26H24N4O4Color and Shape:SolidMolecular weight:456.49Nω-Propyl-L-arginine hydrochloride
CAS:<p>Highly selective and potent inhibitor of nNOS (Ki = 57 nM). Displays 3158-fold and 149-fold selectivity over iNOS and eNOS respectively. Hypotensive in vivo.</p>Formula:C9H21ClN4O2Color and Shape:SolidMolecular weight:252.74T-5342126
CAS:<p>T-5342126: TLR4 antagonist, lowers LPS-induced NO in cells (IC50=27.8 μM) & cytokines in blood, cuts ethanol intake & Iba1 in mice.</p>Formula:C25H32ClN3O3Color and Shape:SolidMolecular weight:457.99
