Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(136 products)
- CXCR(148 products)
- Cell wall(5 products)
- IL Receptor(112 products)
- IκB/IKK(60 products)
- LTR(3 products)
- MALT(23 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(444 products)
- NOD(17 products)
- NOS(63 products)
- Nrf2(79 products)
- PGE Synthase(31 products)
- ROS(69 products)
- TGF-beta/Smad(58 products)
- TLR(66 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
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Found 3045 products of "Immunology and Inflammation"
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CAY10575
CAS:<p>CAY10575 (IKK2-IN-3) is a potent IKK2 inhibitor with potential anti-inflammatory activity for the study of inflammatory and endocrine diseases.</p>Formula:C22H21N3O6S2Color and Shape:SolidMolecular weight:487.55NLRP3-IN-16
CAS:<p>NLRP3-IN-16: potent NLRP3 inflammasome inhibitor; IC50=0.065μM; curbs IL-1β; used in inflammation studies.</p>Formula:C25H25NO5Purity:98%Color and Shape:SolidMolecular weight:419.478A8
CAS:<p>8A8 is a potent NO inhibitor with proinflammatory factor properties, exhibiting an IC50 of 4.7 μM.</p>Formula:C36H37BrClN5O9Purity:98%Color and Shape:SolidMolecular weight:799.06IMD-biphenylB
CAS:<p>IMD-biphenylB: Potent NF-κB inhibitor, curbs tumor growth with low inflammation and toxicity.</p>Formula:C35H33N5O3Purity:98%Color and Shape:SolidMolecular weight:571.67STING agonist-30
CAS:<p>STING agonist-30 is a STING agonist that stimulates STING-dependent immune activation and inhibits HSV, rotavirus and SARS-CoV-2.</p>Formula:C15H16N4O8Purity:98.80%Color and Shape:SolidMolecular weight:380.31CD38 inhibitor 3
CAS:<p>CD38 Inhibitor 3 (compound 1), with an IC50 of 11 nM, is a potent agent that enhances mitochondrial biogenesis, diminishes lactate levels, and augments both NAD</p>Formula:C16H14F3N7O3Purity:98%Color and Shape:SolidMolecular weight:409.32NLRP3-IN-20
CAS:<p>NLRP3-IN-20 (compound 11) is an orally administered inhibitor targeting the NLRP3 inflammasome, exhibiting potent inhibition with an IC50 of 25 nM against IL-1β</p>Formula:C22H27N3O3SPurity:98%Color and Shape:SolidMolecular weight:413.53iNOS inhibitor-10
CAS:<p>iNOS Inhibitor-10, with an IC50 of 65 nM, exhibits antiproliferative effects on triple-negative breast cancer cells [1].</p>Formula:C22H23N3O2SPurity:98%Color and Shape:SolidMolecular weight:393.5COX-2-IN-32
CAS:<p>COX-2-IN-32 (Compound 2f) is a dual inhibitor of iNOS and COX-2, known to downregulate NF-κB expression.</p>Formula:C25H24O6Purity:98%Color and Shape:SolidMolecular weight:420.45SZM679
<p>SZM679: Oral RIPK1 inhibitor, Kd 8.6 nM, weak RIPK3 affinity (>5000 nM). Reduces inflammation, Tau phosphorylation in AD research.</p>Formula:C27H18F5N3O5SPurity:98%Color and Shape:SolidMolecular weight:591.51IMD-catechol
CAS:<p>IMD-catechol: an imidazoquinolinone-based dimer with NF-κB activity; improves CT26 cancer treatment, low toxicity.</p>Formula:C31H34N6O3Purity:98%Color and Shape:SolidMolecular weight:538.64NLRP3-IN-19
CAS:<p>JT001 (NLRP3-IN-19) is a potent, specific, and orally active NLRP3 inhibitor that impedes the assembly of the NLRP3 inflammasome.</p>Formula:C19H22N4O4SPurity:98%Color and Shape:SolidMolecular weight:402.47NF-κB-IN-8
CAS:<p>NF-κB-IN-8 is a competitive antagonist of LPS for MD-2 binding, and it impedes the expression of inflammatory factors by engaging MD-2.</p>Formula:C24H21N3O3Purity:98%Color and Shape:SolidMolecular weight:399.44IMD-biphenylA
CAS:<p>IMD-biphenylA, a novel imidazoquinolinone-based dimer, functions as an NF-κB immunomodulator and enhances the adjuvant properties of small molecule immune</p>Formula:C35H33N5O2Purity:98%Color and Shape:SolidMolecular weight:555.67NF-κB-IN-11
CAS:<p>NF-κB-IN-11 (Compound 3i) is an inhibitor of NF-κB, effectively blocking TNF-α-induced NF-κB pathway activation and the nuclear translocation of NF-κB.</p>Formula:C19H18O5Purity:98%Color and Shape:SolidMolecular weight:326.34Nrf2 activator-4
CAS:<p>Nrf2 activator-4 is an Nrf2 activator for the treatment of fatty liver disease associated with metabolic dysfunction in humans.</p>Formula:C23H24ClF3N2O3Purity:98.53%Color and Shape:SolidMolecular weight:468.9CL264
CAS:<p>CL264, a selective agonist of TLR7, can be used in studies about innate immune signals.</p>Formula:C19H23N7O4Purity:98.01%Color and Shape:SolidMolecular weight:413.43BI605906
CAS:<p>BI605906 is an IKKβ inhibitor that can be used to study inflammatory skin diseases such as psoriasis.</p>Formula:C17H22F2N4O3S2Purity:97.14%Color and Shape:SolidMolecular weight:432.51DHMEQ racemate
CAS:<p>DHMEQ racemate is an NF-κB inhibitor. The activity of DHMEQ racemate is lower than (-)-DHMEQ.</p>Formula:C13H11NO5Purity:98%Color and Shape:SolidMolecular weight:261.23DSR-6434
CAS:<p>DSR-6434 is a selective agonist of TLR7 with antitumor effect. DSR-6434 exhibits EC50s of 7.2 nM and 4.6 nM for human and mouse.</p>Formula:C19H28N8O2Purity:99.78%Color and Shape:SolidMolecular weight:400.48CB2 modulator 1
CAS:<p>CB2 modulator 1 is a potent CB2 modulator. It can be used for the research for immune disorders, osteoporosis, inflammation, renal ischemia.</p>Formula:C18H19F3N4O2Purity:99.6%Color and Shape:SolidMolecular weight:380.36S-MTC
CAS:<p>S-MTC is a selective inhibitor of type I nitric oxide synthase.</p>Formula:C7H15N3O2SPurity:98%Color and Shape:Off-White Powder / White SolidMolecular weight:205.28(R,1R)-Tenofovir amibufenamide
CAS:<p>(R,1R)-Tenofovir amibufenamide ((R,1R)-HS-10234) can be used as a Tenofovir prodrug, which can be taken orally and has antiviral activity.</p>Formula:C22H31N6O5PPurity:98.79% - 99.02%Color and Shape:SolidMolecular weight:490.49AZD8848
CAS:<p>AZD8848 is a selective antedrug agonist of toll-like receptor 7 (TLR7). It is developed for the research of asthma and allergic rhinitis.</p>Formula:C29H43N7O5Color and Shape:SolidMolecular weight:569.7Emlenoflast
CAS:<p>Emlenoflast (MCC7840) is a selective inhibitor of NLRP3 inflammasome.</p>Formula:C19H24N4O3SPurity:97.004% - 98.19%Color and Shape:SolidMolecular weight:388.48Edasalonexent
CAS:<p>Edasalonexent (CAT-1004) is an orally available NF-κB inhibitor for the improvement of Duchenne muscular dystrophy.</p>Formula:C31H42N2O3Purity:99.13% - >99.99%Color and Shape:SolidMolecular weight:490.68Emlenoflast sodium
CAS:<p>Emlenoflast sodium (MCC7840 sodium), a sulfonylurea, is a selective NLRP3 inflammasome inhibitor with an IC50 value of less than 100 nM for NLRP3 inflammasome,</p>Formula:C19H24N4NaO3SColor and Shape:SolidMolecular weight:411.47Bay 65-1942 hydrochloride
CAS:<p>Bay 65-1942 hydrochloride is an inhibitor of ATP-competitive and selective IKKβ.</p>Formula:C22H26ClN3O4Color and Shape:SolidMolecular weight:431.91Gue1654
CAS:<p>Gue1654 is an OXE-R inhibitor and cardiomyocyte apoptosis.Gue1654 can be used for the study of cardiovascular diseases.</p>Formula:C23H17N3OS3Purity:98.02% - 98.04%Color and Shape:SolidMolecular weight:447.6AVE3085
CAS:<p>AVE3085 is an enhancer of endothelial nitric oxide synthase that restores endothelial function and lowers blood pressure in spontaneously hypertensive rats.</p>Formula:C17H13F2NO3Purity:99.87%Color and Shape:SolidMolecular weight:317.29SMA-12b
CAS:<p>SMA-12b is an analog of the immunomodulatory parasite product ES-62 that has immunomodulatory activity and can be used in the study of rheumatoid arthritis.</p>Formula:C13H22INO2SPurity:98.52% - 99.16%Color and Shape:SolidMolecular weight:383.29GSK319347A
CAS:<p>GSK319347A is a dual inhibitor of TBK1 and IKKε that inhibits IKK2 and can be used to study bladder and lung adenocarcinomas.</p>Formula:C22H19N3O5S2Purity:98.42%Color and Shape:SolidMolecular weight:469.53WIN 54954
CAS:<p>WIN 54954 is an orally available antiviral agent that inhibits Coxsackievirus and may be used in the study of small ribonucleic acid virus infections.</p>Formula:C18H20Cl2N2O3Purity:98.98%Color and Shape:SolidMolecular weight:383.27CD73-IN-1
CAS:<p>CD73-IN-1 is a CD73 inhibitor with anticancer activity.</p>Formula:C18H17N3O4SPurity:99.46% - 99.46%Color and Shape:SolidMolecular weight:371.41AVE-9488
CAS:<p>AVE-9488 is a novel endothelial NO synthase (eNOS) enhancer that upregulates eNOS expression, induces NO production, and may ameliorate portal hypertension.</p>Formula:C16H14FNOPurity:99.87%Color and Shape:SolidMolecular weight:255.29JAK2/STAT3-IN-1
CAS:<p>JAK2/STAT3-IN-1 is a GP130 inhibitor with anti-tumor effects and can be used to study inflammation, autoimmunity and cancer.</p>Formula:C34H35BrF3N5O2Purity:97.35%Color and Shape:SolidMolecular weight:682.57SARS-CoV-2 nsp13-IN-1
CAS:<p>SARS-CoV-2 nsp13-IN-1 (C1) inhibits nsp13 ssDNA+ATPase (IC50: 6 μM), not ssDNA-ATPase; useful for COVID-19 research.</p>Formula:C27H20N4O2Purity:99.44%Color and Shape:SolidMolecular weight:432.47M62812
CAS:<p>TLR4 inhibitor blocks LPS-induced NF-κB (IC50=2.4μg/mL), cytokines in PBMCs/HUVECs, and extends life in septic shock mice.</p>Formula:C13H13Cl2N3OSPurity:99.07%Color and Shape:SolidMolecular weight:330.23DDO-7263
CAS:<p>DDO-7263, a 1,2,4-Oxadiazole, boosts Nrf2 by binding Rpn6, blocking 26S proteasome assembly, and has anti-inflammatory effects.</p>Formula:C14H9F2N3OPurity:99.85%Color and Shape:SolidMolecular weight:273.24NFAT Transcription Factor Regulator-1
CAS:<p>NFAT Transcription Factor Regulator-1 is an synthesis inhibitor of IL-2 (IC50 of 182 nM).</p>Formula:C17H10F6N4O2Purity:99.90%Color and Shape:SolidMolecular weight:416.28Zharp2-1
CAS:<p>Zharp2-1 is a RIPK2 inhibitor that alleviates MDP-induced peritonitis symptoms in mice and can be used to study inflammatory bowel disease (IBD).</p>Formula:C19H18N3O2PSPurity:99.41%Color and Shape:SolidMolecular weight:383.4LMT-28
CAS:<p>LMT-28 is an inhibitor of IL-6 and selectively inhibits IL-6-induced phosphorylation of gp130, STAT3, and JAK2.</p>Formula:C17H29NO4Purity:99.88%Color and Shape:SolidMolecular weight:311.42T6167923
CAS:<p>T6167923 inhibits MyD88 signaling, binds TIR domain, blocks dimer formation, lowers SEAP activity, and has anti-inflammatory IC50s ~2.7 μM.</p>Formula:C17H20BrN3O3S2Purity:99.28%Color and Shape:SolidMolecular weight:458.39Zabedosertib
CAS:<p>Zabedosertib (BAY 1834845) is an inhibitor of IRAK4 with immunomodulatory potential.</p>Formula:C20H21F3N4O4SPurity:98.54%Color and Shape:SolidMolecular weight:470.47C3a Receptor Agonist
CAS:<p>C3a Receptor Agonist activates C3aRs, inhibits neutrophil mobilization in ischemia, and promotes neural progenitor differentiation.</p>Formula:C27H35N3O2Purity:99.76%Color and Shape:SolidMolecular weight:433.59NDT 9513727
CAS:<p>NDT 9513727 is a potent, selective and competitive C5aR1 inverse agonist for the study of inflammatory and immune disorders.</p>Formula:C36H35N3O4Purity:99.21%Color and Shape:SolidMolecular weight:573.68Ezurpimtrostat hydrochloride
CAS:<p>Ethacrysta hydrochloride (GNS561 hydrochloride) is a PPT1 inhibitor with antifibrotic properties and may be used in studies of hepatocellular carcinoma.</p>Formula:C25H32Cl2N4Purity:99.84%Color and Shape:SolidMolecular weight:459.45NLRP3/AIM2-IN-2
CAS:<p>NLRP3/AIM2-IN-2, potent species-specific NLRP3 and AIM2 inflammasome pyroptosis inhibitor; IC50 = 0.2392 ± 0.0233 μM.</p>Formula:C15H15NO3Purity:99.67%Color and Shape:SolidMolecular weight:257.28AHR antagonist 2
CAS:<p>AHR antagonist 2 is an antagonist of the aryl hydrocarbon receptor. The IC50s for human AHR and mouse AHR are 0.885 and 2.03 nM, respectively.</p>Formula:C20H17F3N4O3Purity:99.38%Color and Shape:SolidMolecular weight:418.37F092
CAS:<p>F092 is a potent inhibitor of hematopoietic prostaglandin D synthetase (H-PGDS), which can be used to study allergic inflammation and vascular-related diseases.</p>Formula:C20H17N5O2Purity:99.63%Color and Shape:SolidMolecular weight:359.38
