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Immunology and Inflammation

Immunology and Inflammation

Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.

Subcategories of "Immunology and Inflammation"

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Found 3045 products of "Immunology and Inflammation"

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  • DDG-39

    CAS:
    <p>DDG-39 (1-(2,3-dideoxy-2-fluoropentofuranosyl)cytosine) possesses antiviral activity with potent and selective anti-HIV-1 and HBV activity in cell culture.</p>
    Formula:C9H12FN3O3
    Purity:99.81% - >99.99%
    Color and Shape:Solid
    Molecular weight:229.21
  • Selnoflast

    CAS:
    <p>Selnoflast (RO-7486967) is an orally active, potent and selective NLRP3 inhibitor for the study of coronary arteries and ulcerative colitis.</p>
    Formula:C20H29N3O3S
    Purity:98.54% - 99.66%
    Color and Shape:Solid
    Molecular weight:391.53
  • GSK2983559 free acid

    CAS:
    <p>GSK2983559 free acid selectively inhibits RIP2, reducing inflammatory cytokines in human bowel disease.</p>
    Formula:C21H23N4O7PS2
    Purity:97.8700% - 98.61%
    Color and Shape:Solid
    Molecular weight:538.53
  • FEN1-IN-3

    CAS:
    <p>FEN1-IN-3 is a human flap endonuclease-1 ( hFEN1 ) inhibitor that stabilizes hFEN1 with an EC 50 of 6.8 μM .</p>
    Formula:C15H12N2O4
    Purity:98.16%
    Color and Shape:Solid
    Molecular weight:284.27
  • BRD56491

    CAS:
    <p>BRD56491 is a small molecule ROS enhancer and a bioprobe for the detection of cancer.</p>
    Formula:C20H14O2
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:286.32
  • Rabeximod

    CAS:
    <p>Rabeximod, an immunomodulator, eases autoimmune diseases, inhibits arthritis, and aids brain recovery post-injury by blocking inflammation.</p>
    Formula:C22H24ClN5O
    Purity:99.99%
    Color and Shape:Solid
    Molecular weight:409.91
  • T6167923

    CAS:
    <p>T6167923 inhibits MyD88 signaling, binds TIR domain, blocks dimer formation, lowers SEAP activity, and has anti-inflammatory IC50s ~2.7 μM.</p>
    Formula:C17H20BrN3O3S2
    Purity:99.28%
    Color and Shape:Solid
    Molecular weight:458.39
  • Zharp2-1

    CAS:
    <p>Zharp2-1 is a RIPK2 inhibitor that alleviates MDP-induced peritonitis symptoms in mice and can be used to study inflammatory bowel disease (IBD).</p>
    Formula:C19H18N3O2PS
    Purity:99.41%
    Color and Shape:Solid
    Molecular weight:383.4
  • NLRP3-IN-10

    CAS:
    <p>NLRP3-IN-10 (ZVN26391) is a strong NLRP3 inhibitor, IC50 251.1 nM, that reduces IL-1β and ASC speck, hindering inflammasome activation.</p>
    Formula:C17H14BrFO3
    Purity:99.06%
    Color and Shape:Solid
    Molecular weight:365.19
  • Zabedosertib

    CAS:
    <p>Zabedosertib (BAY 1834845) is an inhibitor of IRAK4 with immunomodulatory potential.</p>
    Formula:C20H21F3N4O4S
    Purity:98.54%
    Color and Shape:Solid
    Molecular weight:470.47
  • NFAT Transcription Factor Regulator-1

    CAS:
    <p>NFAT Transcription Factor Regulator-1 is an synthesis inhibitor of IL-2 (IC50 of 182 nM).</p>
    Formula:C17H10F6N4O2
    Purity:99.90%
    Color and Shape:Solid
    Molecular weight:416.28
  • B022

    CAS:
    <p>B022 is an NF-κB-induced kinase (NIK) inhibitor that protects the liver from inflammation and injury caused by oxidative stress and toxins.</p>
    Formula:C19H16ClN5OS
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:397.88
  • LDC7559

    CAS:
    <p>LDC7559 inhibits gasdermin D (GSDMD) by blocking neutrophil extracellular trap (NET) at late stage.</p>
    Formula:C20H19N3O3
    Purity:99.8%
    Color and Shape:Soild
    Molecular weight:349.38
  • Phox-I2

    CAS:
    <p>Phox-I2 is an NOX2-specific inhibitor. Phox-I2 reverts ROS-accumulation and leads to refusion of mitochondrial networks.</p>
    Formula:C18H15N3O4
    Purity:99.73%
    Color and Shape:Solid
    Molecular weight:337.33
  • Resiniferatoxin

    CAS:
    <p>Resiniferatoxin ((+)-Resiniferatoxin) is a highly potent synthetic TRPV1 agonist.Cost-effective and quality-assured.</p>
    Formula:C37H40O9
    Purity:93.08% - 99.34%
    Color and Shape:Solid
    Molecular weight:628.71
  • C3a Receptor Agonist

    CAS:
    <p>C3a Receptor Agonist activates C3aRs, inhibits neutrophil mobilization in ischemia, and promotes neural progenitor differentiation.</p>
    Formula:C27H35N3O2
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:433.59
  • h-NTPDase8-IN-1

    CAS:
    <p>h-NTPDase8-IN-1 is a specific aminosulfonylbenzamide inhibitor of h-NTPDases8, which can be used to study diseases caused by aberrant h-NTPDase expression.</p>
    Formula:C10H10ClNO4S
    Purity:98.78% - 99.59%
    Color and Shape:Solid
    Molecular weight:275.71
  • Thiodigalactoside

    CAS:
    <p>Thiodigalactoside (TDG), a non-metabolizable disaccharide, serves as an orally active, potent galectin (GAL) inhibitor, exhibiting Kd values of 24 μM and 49 μM</p>
    Formula:C12H22O10S
    Purity:99.90%
    Color and Shape:Solid
    Molecular weight:358.36
  • YM-53403

    CAS:
    <p>YM-53403: Antiviral that combats both RSV subgroup A/B, treats respiratory infections.</p>
    Formula:C36H29N3O3S
    Purity:98.49% - 98.85%
    Color and Shape:Solid
    Molecular weight:583.7
  • Complement C5-IN-1

    CAS:
    <p>Complement C5-IN-1 is a small-molecule inhibitor of complement component 5 protein (C5).</p>
    Formula:C24H32N2O6
    Purity:98.27%
    Color and Shape:Solid
    Molecular weight:444.52
  • LMT-28

    CAS:
    <p>LMT-28 is an inhibitor of IL-6 and selectively inhibits IL-6-induced phosphorylation of gp130, STAT3, and JAK2.</p>
    Formula:C17H29NO4
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:311.42
  • CMX-521

    CAS:
    <p>CMX521: an antiviral for norovirus, effective against rotavirus; inhibits viral RNA polymerase.</p>
    Formula:C13H17N5O5
    Purity:99.57%
    Color and Shape:Solid
    Molecular weight:323.3
  • Antiviral agent 17

    CAS:
    <p>Antiviral agent 17, EC50 0.015 μM in human assay, effective against murine norovirus, may aid infectious/malignant disease research.</p>
    Formula:C11H14N4O4
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:266.25
  • Biofor 389

    CAS:
    <p>Biofor 389 (BF389) has anti-inflammatory activity and can be used to study arthritis.</p>
    Formula:C20H29NO3
    Purity:98.84% - 99.97%
    Color and Shape:Solid
    Molecular weight:331.45
  • RIG012

    CAS:
    <p>RIG012 is a potent RIG-I inhibitor with an IC50 value of 0.71 μM measured by NADH-coupled ATPase.RIG012 inhibited the expression of IFN-β and ISG hRsad2.</p>
    Formula:C23H21NO3
    Purity:99.53%
    Color and Shape:Solid
    Molecular weight:359.42
  • CPG-52364

    CAS:
    <p>CPG-52364 is a small molecule compound that interacts between an endosomal TLR and its ligand and is a candidate for the treatment of psoriasis.</p>
    Formula:C27H36N6O3
    Purity:99.99%
    Color and Shape:Solid
    Molecular weight:492.61
  • EIDD-2749

    CAS:
    <p>EIDD-2749 (4'-Fluorouridine), an oral drug, inhibits RdRp, halts RSV/SARS-CoV-2 replication, and fights HCV/LCMV.</p>
    Formula:C9H11FN2O6
    Purity:97.39%
    Color and Shape:Solid
    Molecular weight:262.19
  • Cindunistat

    CAS:
    <p>Cindunistat (free base) is an orally available selective iNOS inhibitor for the study of arthritis.</p>
    Formula:C8H17N3O2S
    Purity:99% - >99.99%
    Color and Shape:Solid
    Molecular weight:219.3
  • M62812

    CAS:
    <p>TLR4 inhibitor blocks LPS-induced NF-κB (IC50=2.4μg/mL), cytokines in PBMCs/HUVECs, and extends life in septic shock mice.</p>
    Formula:C13H13Cl2N3OS
    Purity:99.07%
    Color and Shape:Solid
    Molecular weight:330.23
  • Rociclovir

    CAS:
    <p>Rociclovir has antiviral activity and is used to treat viral infections.</p>
    Formula:C15H25N5O3
    Purity:99.19%
    Color and Shape:Solid
    Molecular weight:323.39
  • Rufigallol

    CAS:
    <p>Rufigallol, an anthraquinone with six OH groups, induces DLC and fluoresces when aggregated, showing antimalarial effects with vitamin C and ketones.</p>
    Formula:C14H8O8
    Purity:98.92% - 99.27%
    Color and Shape:Solid
    Molecular weight:304.21
  • AHR antagonist 2

    CAS:
    <p>AHR antagonist 2 is an antagonist of the aryl hydrocarbon receptor. The IC50s for human AHR and mouse AHR are 0.885 and 2.03 nM, respectively.</p>
    Formula:C20H17F3N4O3
    Purity:99.38%
    Color and Shape:Solid
    Molecular weight:418.37
  • CDDO-EA

    CAS:
    <p>CDDO-EA (CDDO ethyl amide) is an activator of the Nrf2/antioxidant response element.</p>
    Formula:C33H46N2O3
    Purity:99.66%
    Color and Shape:Solid
    Molecular weight:518.73
  • IL-4-inhibitor-1

    CAS:
    <p>IL-4 inhibitor: Binds IL-4 (Kd=1.8 μM), blocks activity (EC50=1.81 μM), selective vs. IL-13, stops IL-4-JAK1-STAT6 in THP-1 monocytes (EC50=3.1 μM).</p>
    Formula:C18H12FN3O2
    Purity:98.78% - 99.53%
    Color and Shape:Solid
    Molecular weight:321.31
  • NO-prednisolone

    CAS:
    <p>NO-prednisolone (NCX-1015) is a compound that effectively stimulates the production of IL-10 in vivo.</p>
    Formula:C29H33NO9
    Purity:98.65%
    Color and Shape:Solid
    Molecular weight:539.57
  • MK-28

    CAS:
    <p>MK-28 is a PERK agonist that reduces toxicity in a Huntington's disease model.MK-28 has a significant killing effect on MK28 gastric cancer cells.</p>
    Formula:C24H20N4O2
    Color and Shape:Solid
    Molecular weight:396.44
  • IRAK4-IN-20

    CAS:
    <p>IRAK4-IN-20 is a potent and orally active IRAK4 inhibitor (IC50:3.55 nM).</p>
    Formula:C22H25F3N4O3
    Purity:98.09%
    Color and Shape:Solid
    Molecular weight:450.45
  • BBIQ

    CAS:
    <p>BBIQ is a powerful vaccine adjuvant that enhances innate immune responses and a potent and selectively toll-like receptor 7 (TLR7) agonist with an EC50 of  59.1</p>
    Formula:C21H22N4
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:330.43
  • JC124

    CAS:
    <p>JC124 is an inhibitor of NLRP3 Inflammasome and exhibits neuroprotective and anti-inflammatory activities.</p>
    Formula:C17H19ClN2O4S
    Purity:99.64%
    Color and Shape:Solid
    Molecular weight:382.86
  • Letosteine

    CAS:
    <p>Letosteine, an oral expectorant, treats acute/chronic respiratory diseases by dissolving mucus and reducing inflammation.</p>
    Formula:C10H17NO4S2
    Purity:96.03%
    Color and Shape:Solid
    Molecular weight:279.38
  • HS271

    CAS:
    <p>HS271 is a selective, highly potent and orally active IRAK4 inhibitor (IC50= 7.2 μM).</p>
    Formula:C21H24F3N5O2
    Purity:98.79%
    Color and Shape:Solid
    Molecular weight:435.44
  • CPS-11

    CAS:
    <p>CPS-11, a Thalidomide analogue, shows potent, broad antitumor activity, especially in multiple myeloma cells.</p>
    Formula:C14H12N2O5
    Purity:99.8% - 99.98%
    Color and Shape:Solid
    Molecular weight:288.26
  • DDO-7263

    CAS:
    <p>DDO-7263, a 1,2,4-Oxadiazole, boosts Nrf2 by binding Rpn6, blocking 26S proteasome assembly, and has anti-inflammatory effects.</p>
    Formula:C14H9F2N3O
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:273.24
  • ER-34122

    CAS:
    <p>ER-34122, a novel orally available dual 5-lipoxygenase/cyclooxygenase inhibitor with potent anti-inflammatory activity.</p>
    Formula:C27H26ClN3O5
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:507.96
  • IL-2-IN-1

    CAS:
    <p>IL-2-IN-1 is a potent inhibitor of IL-2 (IC50: 1978 nM) and exhibits anti-proliferative effects.</p>
    Formula:C17H12F6N4O2
    Purity:99.6%
    Color and Shape:Solid
    Molecular weight:418.29
  • IQP-0528

    CAS:
    <p>IQP-0528: Potent NNRTI, blocks HIV entry, microbicidal gel, EC50: 0.2 nM for HIV-1, 100 nM for HIV-2.</p>
    Formula:C20H24N2O3
    Purity:98.36% - >99.99%
    Color and Shape:Solid
    Molecular weight:340.42
  • BN-82451 2HCl

    CAS:
    <p>BN-82451, a cyclooxygenase inhibitor, is used potentially for the treatment of Huntington’s disease.</p>
    Formula:C18H28Cl2N2OS
    Purity:99.84% - >99.99%
    Color and Shape:Solid
    Molecular weight:391.4
  • APX-115

    CAS:
    <p>APX-115 (Ewha-18278) (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4).</p>
    Formula:C17H18ClN3O
    Purity:98.62%
    Color and Shape:Solid
    Molecular weight:315.8
  • TLR7/8-IN-1

    CAS:
    <p>TLR7/8-IN-1, a crystalline TLR7/TLR8 inhibitor, is a valuable compound for autoimmune disease research.Cost-effective and quality-assured.</p>
    Formula:C29H40N8O2
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:532.68
  • SC-75416

    CAS:
    <p>SC-75416, a cyclooxygenase-2 (COX-2) inhibitor, is used potentially for the treatment of postoperative inflammation.</p>
    Formula:C15H14ClF3O3
    Purity:98.67% - 98.67%
    Color and Shape:Solid
    Molecular weight:334.72