Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(136 products)
- CXCR(148 products)
- Cell wall(5 products)
- IL Receptor(112 products)
- IκB/IKK(60 products)
- LTR(3 products)
- MALT(23 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(444 products)
- NOD(17 products)
- NOS(63 products)
- Nrf2(79 products)
- PGE Synthase(31 products)
- ROS(69 products)
- TGF-beta/Smad(58 products)
- TLR(66 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
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Found 3045 products of "Immunology and Inflammation"
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NDT 9513727
CAS:<p>NDT 9513727 is a potent, selective and competitive C5aR1 inverse agonist for the study of inflammatory and immune disorders.</p>Formula:C36H35N3O4Purity:99.21%Color and Shape:SolidMolecular weight:573.68NFATc1-IN-1
CAS:<p>NFATc1-IN-1 (A04) inhibits RANKL-induced osteoclast formation with 1.57 μM IC50, blocking NFATc1 translocation.</p>Formula:C13H8F2INO2Purity:99.64%Color and Shape:SolidMolecular weight:375.11RIPK1-IN-9
CAS:<p>RIPK1-IN-9, a potent dihydronaphthone, selectively inhibits RIPK1 with IC50 of 2 nM (U937) and 1.3 nM (L929).</p>Formula:C26H25FN6O2Purity:99.85%Color and Shape:SolidMolecular weight:472.51Ezurpimtrostat hydrochloride
CAS:<p>Ethacrysta hydrochloride (GNS561 hydrochloride) is a PPT1 inhibitor with antifibrotic properties and may be used in studies of hepatocellular carcinoma.</p>Formula:C25H32Cl2N4Purity:99.84%Color and Shape:SolidMolecular weight:459.45NLRP3/AIM2-IN-2
CAS:<p>NLRP3/AIM2-IN-2, potent species-specific NLRP3 and AIM2 inflammasome pyroptosis inhibitor; IC50 = 0.2392 ± 0.0233 μM.</p>Formula:C15H15NO3Purity:99.67%Color and Shape:SolidMolecular weight:257.28ABT-963
CAS:<p>ABT-963: COX-2 inhibitor for osteoarthritis/pain with high selectivity, potency, and gastric safety.</p>Formula:C22H22F2N2O5SPurity:98% - 99.85%Color and Shape:SolidMolecular weight:464.48CT-2584
CAS:<p>CT-2584: angiogenesis & lysophosphatidic acid transferase inhibitor; alters phospholipid synthesis, increasing PI in tumor cells.</p>Formula:C30H55N5O3Purity:97.68% - 99.77%Color and Shape:SolidMolecular weight:533.79ABI-1968
CAS:<p>ABI-1968 has antiviral and antitumor activity and can be used to study immune system diseases.</p>Formula:C35H58N5O6PPurity:98.54%Color and Shape:SolidMolecular weight:675.839Azalanstat
CAS:<p>Azalanstat (RS 21607) is a mammalian lanosterol 14-alpha-demethylase inhibitor with hypocholesterolemic activity.</p>Formula:C22H24ClN3O2SPurity:99.41% - 99.85%Color and Shape:SolidMolecular weight:429.96F092
CAS:<p>F092 is a potent inhibitor of hematopoietic prostaglandin D synthetase (H-PGDS), which can be used to study allergic inflammation and vascular-related diseases.</p>Formula:C20H17N5O2Purity:99.63%Color and Shape:SolidMolecular weight:359.38Desmosterol
CAS:<p>Desmosterol (24-Dehydrocholesterol) is a cholesterol biosynthesis intermediate that inhibits macrophage inflammatory vesicle activation .</p>Formula:C27H44OPurity:>99.99%Color and Shape:SolidMolecular weight:384.64IRAK4-IN-28
CAS:<p>IRAK4-IN-28 (compound 42), an orally-active IRAK4 inhibitor (IC50=8.9 nM), exhibits strong binding affinity with a Kd of 0.58 nM for the target enzyme.</p>Formula:C27H31N9O3Purity:98%Color and Shape:SolidMolecular weight:529.59IMD-vanillin
CAS:<p>IMD-vanillin is a novel compound characterized as an imidazoquinolinone-derived dimer with NF-κB immunomodulatory properties.</p>Formula:C37H45N7O4Purity:98%Color and Shape:SolidMolecular weight:651.8NLRP3-IN-21
CAS:<p>NLRP3-IN-21 (compound L38) is an inhibitor of the NLRP3 inflammasome that possesses anti-inflammatory properties.</p>Formula:C20H13Cl2F3N6O2SPurity:98%Color and Shape:SolidMolecular weight:529.32ICy-Q
CAS:<p>ICy-Q, a NIR reagent activated by NQO-1, triggers pyroptosis in pancreatic cancer cells, aiding diagnosis.</p>Formula:C48H50I2N2O5Purity:98%Color and Shape:SolidMolecular weight:988.73IMD-biphenylC
CAS:<p>IMD-biphenylC: New, dual-action imidazoquinolinone dimer; inhibits tumor growth, low inflammation/toxicity.</p>Formula:C35H33N5O3Purity:98%Color and Shape:SolidMolecular weight:571.67hnNOS-IN-2
CAS:<p>Compound 17, also known as hnNOS-IN-2, is an inhibitor of human neuronal nitric oxide synthase (hnNOS) that exhibits good metabolic stability.</p>Formula:C18H23F2N3Purity:98%Color and Shape:SolidMolecular weight:319.39RIP1 kinase inhibitor 4
CAS:<p>RIP1 Kinase Inhibitor 4 (Compound 3) is an effective inhibitor of RIP1K, exhibiting an EC50 of ≤ 1000 nM [1].</p>Formula:C23H23N5Purity:98%Color and Shape:SolidMolecular weight:369.46Anti-inflammatory agent 46
CAS:<p>Anti-inflammatory agent 46 (compound 7h), exhibiting nitric oxide (NO) inhibitory properties, demonstrates a high affinity for iNOS through low binding energies</p>Formula:C24H19FN2O3SPurity:98%Color and Shape:SolidMolecular weight:434.48STING-IN-5
CAS:<p>STING-IN-5 suppresses NO synthesis in macrophages, inhibits STING pathway with IC50 of 1.15 μM, and may aid anti-inflammatory and sepsis research.</p>Formula:C47H67NO9S2Purity:98%Color and Shape:SolidMolecular weight:854.17Trovafloxacin mesylate
CAS:<p>Trovafloxacin: broad-spectrum fluoroquinolone, blocks DNA gyrase/topoisomerase IV and PANX1 channel (IC50=4μM).</p>Formula:C21H19F3N4O6SPurity:99.18%Color and Shape:SolidMolecular weight:512.46Benoxaprofen
CAS:<p>Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.</p>Formula:C16H12ClNO3Purity:98.87%Color and Shape:SolidMolecular weight:301.72IKK-IN-1
CAS:IKK-IN-1 is an inhibitor of IKK.Formula:C22H26ClN3O4Purity:98%Color and Shape:SolidMolecular weight:431.91PK68
CAS:<p>PK68 selectively inhibits RIPK1 (IC50=90nM), potentially useful in inflammation and cancer metastasis studies.</p>Formula:C22H24N4O3SPurity:98.09% - 99.64%Color and Shape:SolidMolecular weight:424.52BD-AcAc 2
CAS:<p>BD-AcAc 2 (Ketone Ester) is a ketone monoester and can be used as a source of oral nutritional ketones.</p>Formula:C8H16O4Purity:99.62%Color and Shape:SolidMolecular weight:176.21IL-17A antagonist 3
CAS:<p>IL-17A antagonist 3 is an IL-17A antagonist.</p>Formula:C33H33ClN6O4Purity:98%Color and Shape:SolidMolecular weight:613.11GGTI 2147
CAS:<p>GGTI 2147 decreased Rac1 activity, down-regulated p65 expression, and ameliorated OGD/R-induced neuronal apoptosis.</p>Formula:C28H30N4O3Purity:98.69%Color and Shape:SolidMolecular weight:470.56Aminoguanidine hemisulfate
CAS:<p>Aminoguanidine hemisulfate, an inhibitor of nitric oxide synthases (NOS) and reactive oxygen species (ROS), effectively suppresses ANE-induced ROS production in</p>Formula:CH6N4H2SO4Purity:98%Color and Shape:SolidMolecular weight:123.115Stobadine
CAS:<p>Stobadine, a potent antioxidant, safeguards endoplasmic reticulum (ER) membrane fluidity against free radical-induced changes.</p>Formula:C13H18N2Purity:98%Color and Shape:SolidMolecular weight:202.3Lipid peroxidation inhibitor 1
CAS:<p>Lipid peroxidation inhibitor 1 is an inhibitor of lipid peroxidation (IC50: 0.07 μM).</p>Formula:C24H32N2OPurity:98%Color and Shape:SolidMolecular weight:364.52Dapsone hydroxylamine
CAS:<p>Dapsone hydroxylamine (DDS-NOH) promotes methemoglobinemia, impedes catalase (CAT) activity, and suppresses the generation of reactive oxygen species, while</p>Formula:C12H12N2O3SPurity:98%Color and Shape:SolidMolecular weight:264.3α-Pyridoin
CAS:<p>α-Pyridoin (α-pyridoin) is an enediol (enediol) compound that acts as a unique antioxidant.</p>Formula:C12H12N2O2Color and Shape:SolidMolecular weight:216.24NLRP3-IN-17
CAS:<p>NLRP3-IN-17 is a potent, selective, and orally active inhibitor of the NLRP3 inflammasome, demonstrating an IC50 of 7 nM.</p>Formula:C21H22N4O2SPurity:98%Color and Shape:SolidMolecular weight:394.49Dimethoxycurcumin
CAS:Dimethoxycurcumin is a stable curcumin analog causing epigenetic shifts in leukemia cells, affecting gene expression.Formula:C23H24O6Purity:99.87%Color and Shape:SolidMolecular weight:396.43CD73-IN-4
CAS:<p>CD73-IN-4 is a potent and selective methylenephosphonic acid CD73 inhibitor</p>Formula:C16H23ClN5O7PPurity:98.61%Color and Shape:SolidMolecular weight:463.81IFN α-IFNAR-IN-1 hydrochloride
CAS:<p>IFN alpha-IFNAR-IN-1 HCl blocks IFN-α/IFNAR binding; IC50 2-8 μM in BM-pDCs' MVA-induced IFN-α response.</p>Formula:C18H18ClNSPurity:99.77%Color and Shape:SolidMolecular weight:315.86ACHP Hydrochloride
CAS:<p>ACHP Hydrochloride (IKK-2 Inhibitor VIII) is a highly potent and selective IKK-β inhibitor with an IC50 of 8.5 nM.</p>Formula:C21H25ClN4O2Purity:99.83%Color and Shape:SolidMolecular weight:400.9ML-090
CAS:<p>ML-090 is NOX1-specific inhibitor(IC50 = 90 nM) which is >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50s >10 μM).</p>Formula:C14H10N4Purity:98.55%Color and Shape:SolidMolecular weight:234.26TLR7 agonist 23
CAS:<p>TLR7 agonist23 (compound 12b) is a potent agonist of Toll-like receptor-7 (TLR7), with an EC50 value of 0.15 uM. It is suitable for research in immune diseases.</p>Formula:C21H22N4O2Color and Shape:SolidMolecular weight:362.42GBT1118
CAS:<p>GBT1118 is an orally active allosteric modulator of haemoglobin oxygen affinity, enhancing tolerance to acute severe hypoxia and suitable for hypoxia research.</p>Formula:C19H20N2O4Purity:99.69%Color and Shape:SolidMolecular weight:340.37(Rac)-BAY-985
CAS:<p>(Rac)-BAY-985 is a potent, ATP-competitive and selective inhibitor of TBK1(IC50 of 1.5 nM),with antitumor efficacy.</p>Formula:C27H30F3N9OPurity:98%Color and Shape:SolidMolecular weight:553.58h-NTPDase-IN-3
CAS:<p>h-NTPDase-IN-3 is an h-NTPDase inhibitor that inhibits h-NTPDase1, h-NTPDase2, h-NTPDase3 and h-NTPDase8.</p>Formula:C16H10N4SPurity:98.24%Color and Shape:SolidMolecular weight:290.34Cergutuzumab amunaleukin
CAS:<p>Cergutuzumab amunaleukin (CEA-IL2v) is a CEA-targeted IL-2 variant immunocytokine for combination cancer immunotherapy with anti-tumor activity.</p>Purity:98% (SDS-PAGE); 99.7% (SEC-HPLC) - 98% (SDS-PAGE); 99.7% (SEC-HPLC)Color and Shape:LiquidMolecular weight:162.05 kDaFenquinotrione
CAS:<p>Fenquinotrione, a 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor, exhibits IC50 values of 27.2 and 44.7 nM against HPPD from rice and Arabidopsis thaliana</p>Formula:C22H17ClN2O5Color and Shape:SolidMolecular weight:424.83MALT1-IN-7
CAS:<p>MALT1-IN-7 (compound 142b) is a potent inhibitor of MALT1 protease with potential for cancer research.</p>Formula:C19H17F3N8O2SColor and Shape:SolidMolecular weight:478.45IRAK inhibitor 3
CAS:<p>IRAK inhibitor 3 is an interleukin-1 (IL-1) receptor-associated kinase (IRAK) modulator.</p>Formula:C21H21N5O4SPurity:98.86%Color and Shape:SolidMolecular weight:439.49Keap1-Nrf2-IN-15
CAS:<p>Keap1-Nrf2-IN-15 (Compound 24a) is a potent inhibitor of the Keap1-Nrf2 protein-protein interaction, displaying IC50 values of 77 nM in a fluorescence</p>Formula:C39H35N3O12S2Color and Shape:SolidMolecular weight:801.84GSK2256294A
CAS:<p>GSK2256294A (GSK 2256294) is potent, selective inhibitor of recombinant human, rat and mouse sEH with IC50 of 27 pM, 61 pM and 189 pM, respectively.</p>Formula:C21H24F3N7OPurity:99.86% - 99.86%Color and Shape:SolidMolecular weight:447.46TLR8 agonist 6
CAS:<p>Compound A, a potent TLR8 agonist, exhibits an EC50 of 0.052 µM and promotes the production of IL-12p40 in human PBMCs with an EC50 of 0.031 µM.</p>Formula:C19H29N7O2Color and Shape:SolidMolecular weight:387.48TLR7 agonist 4
CAS:<p>TLR7 agonist 4 (Compound 1.2) is a TLR7 agonist (EC50: 4.3 nM).</p>Formula:C23H34N6O3Color and Shape:SolidMolecular weight:442.55
