Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(136 products)
- CXCR(148 products)
- Cell wall(5 products)
- IL Receptor(112 products)
- IκB/IKK(60 products)
- LTR(3 products)
- MALT(23 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(444 products)
- NOD(17 products)
- NOS(63 products)
- Nrf2(78 products)
- PGE Synthase(31 products)
- ROS(69 products)
- TGF-beta/Smad(58 products)
- TLR(66 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
Show 11 more subcategories
Found 3044 products of "Immunology and Inflammation"
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AMPCP
CAS:<p>AMPCP is an Ecto-5'-nucleotidase (CD73) inhibitor.</p>Formula:C11H15N5Na2O9P2Color and Shape:SolidMolecular weight:469.19TLR4 agonist-1
CAS:<p>TLR4 agonist-1 (compound 17a) serves as a potent activator of Toll-like Receptor 4 (TLR4) and stimulates the production of MIP-1β in RAW 264.7 and MM6 cells [1</p>Formula:C81H158N3O15PColor and Shape:SolidMolecular weight:1445.11TBK1-IN-1
CAS:<p>TBK1-IN-1 is a TANK-binding kinase 1 inhibitor with anticancer activity.TBK1-IN-1 inhibits the expression of TBK1 downstream target genes, cxcl10 and ifnβ.</p>Formula:C27H37N7O2Purity:>99.99%Color and Shape:SolidMolecular weight:491.63NVS-MALT1
CAS:<p>NVS-MALT1 is an allosteric inhibitor of MALT1 [1].</p>Formula:C24H27ClF3N5O4SColor and Shape:SolidMolecular weight:574.02Oxidized ATP trisodium salt
CAS:<p>Oxidized ATP trisodium salt (oATP) is a broad-spectrum inhibitor of P2 receptors, irreversibly antagonizing P2X7R activation and inhibiting c-reactive protein (</p>Formula:C10H11N5Na3O13P3Purity:98%Color and Shape:SolidMolecular weight:571.11PDE4-IN-8
CAS:<p>PDE4-IN-8 is a potent PDE4 inhibitor with IC50 0.93 nM for PDE4B2 and minor impact on IL13, IL4, IFNy (IC50: 4.04, 36.33, 2394 nM).</p>Formula:C18H22BNO4Color and Shape:SolidMolecular weight:327.18Ginsenoside Rk1
CAS:<p>Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures.</p>Formula:C42H70O12Purity:98.46% - 99.13%Color and Shape:SolidMolecular weight:767Vipoglanstat
CAS:<p>Vipoglanstat: inhibits prostaglandin E synthase, anti-inflammatory, reduces leukocyte infiltration and lung injury from endotoxin/sepsis.</p>Formula:C30H34Cl2F5N5O3Color and Shape:SolidMolecular weight:678.52TLR7 agonist 16
CAS:<p>TLR7 agonist 16 (compound 16d) is a potent activator of TLR7 with an EC50 value of 18 nM.</p>Formula:C25H29N5O2Color and Shape:SolidMolecular weight:431.53STING-IN-7
CAS:<p>STING-IN-7 (compound 21) serves as a potent inhibitor of the stimulator of interferon genes (STING) pathway, demonstrating an inhibitory concentration (IC50) of</p>Formula:C16H14ClN3OPurity:98%Color and Shape:SolidMolecular weight:299.76PROTAC IRAK4 degrader-8
CAS:<p>PROTAC IRAK4 Degrader-8 (Compound 2) is a PROTAC designed to target IRAK4 with an IC50 of 15.5 nM [1].</p>Formula:C43H50ClF2N11O5Purity:98%Color and Shape:SolidMolecular weight:874.38FEN1-IN-6
CAS:<p>FEN1-IN-6 (compound 9) is a potent Flap endonuclease-1 (FEN1, IC50 = 10 nM) inhibitor, crucial for DNA damage repair in mammalian cells, and additionally</p>Formula:C12H8N2O5S2Purity:98%Color and Shape:SolidMolecular weight:324.33GSK840
CAS:<p>GSK840 (GSK'840) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds the RIP3 kinase domain (IC50: 0.9 nM), and inhibits kinase</p>Formula:C21H23N3O3Purity:99.7%Color and Shape:SolidMolecular weight:365.43Tyrosinase-IN-22
CAS:<p>Tyrosinase-IN-22 (compound 4) serves as a potent inhibitor for tyrosinase substrates, namely L-tyrosine and L-dopa, exhibiting inhibitory concentrations (IC50s) of 60 nM and 30 nM, respectively. Additionally, it demonstrates significant antioxidant and anti-melanogenic properties, making it suitable for related research endeavors [1].</p>Formula:C7H5ClN2SColor and Shape:SolidMolecular weight:184.64Anti-inflammatory agent 65
CAS:<p>Anti-inflammatory agent 65 (compound 29), a Hederagonic acid derivative, exhibits potent activity by inhibiting nitric oxide (NO) release, nuclear translocation</p>Formula:C49H71NO6S2Purity:98%Color and Shape:SoildMolecular weight:834.22GW274150 dihydrochloride
CAS:<p>GW274150 (dihydrochloride) is a potent, selective inhibitor of human and rat inducible nitric oxide synthase (iNOS), exhibiting oral activity and NADPH-</p>Formula:C8H19Cl2N3O2SPurity:98%Color and Shape:SolidMolecular weight:292.23TLR7 agonist 15
CAS:<p>TLR7 agonist 15 (compound 16b) is a potent activator of mouse macrophages and hPBMCs, demonstrating an EC50 of 18 nM.</p>Formula:C26H31N5OColor and Shape:SolidMolecular weight:429.56CAY10464
CAS:<p>CAY10464 (AHR antagonist 7) is an AHR antagonist for the study of cancer and metabolic diseases.</p>Formula:C15H12Cl2OPurity:99.96%Color and Shape:SolidMolecular weight:279.16IR-Crizotinib
CAS:<p>IR-Crizotinib is a conjugate of the near-infrared dye IR-786 and Crizotinib, an NF-κB-inducing kinase (NIK) inhibitor, with an IC50 of 3.381 μM for intracranial</p>Formula:C53H57Cl2FIN7OPurity:98%Color and Shape:SolidMolecular weight:1024.88Antitumor agent-114
CAS:<p>Antitumor Agent-114, a potent STING (stimulator of interferon genes) agonist, activates immune responses and diminishes tumor size in mouse breast cancer models</p>Formula:C39H50F2N10O13P2Purity:98%Color and Shape:SolidMolecular weight:966.82RIPK1-IN-16
CAS:<p>RIPK1-IN-16 is an orally active, potent RIPK1 inhibitor that mitigates excessive inflammation via inhibition of RIPK1-mediated necroptosis in vivo.</p>Formula:C20H19N5O2SPurity:98%Color and Shape:SolidMolecular weight:393.46NF-κB-IN-13
CAS:<p>NF-κB-IN-13 (compound 12) markedly suppresses LPS-induced NF-κB activation and NO synthesis in RAW264.7 macrophages, exhibiting anti-inflammatory properties [1</p>Formula:C20H20O5Purity:98%Color and Shape:SolidMolecular weight:340.37BI 7446
CAS:<p>BI 7446 is a potent and selective cyclic dinucleotide (CDN)-based stimulator of interferon genes (STING) agonist capable of activating all five STING variants</p>Formula:C20H22FN9O10P2S2Purity:98%Color and Shape:SolidMolecular weight:693.52FCE-27164
CAS:<p>FCE-27164 inhibits PDGF-β and IL-7 receptor binding, potentially modulating inflammatory and immune responses for therapeutic applications.</p>Formula:C45H34N10Na6O23S6Purity:96.04%Color and Shape:SolidMolecular weight:1413.11TLR7 agonist 14
CAS:<p>Compound 17b, a TLR7 agonist also known as TLR7 agonist 14, exhibits high potency with an EC50 of 18 nM.</p>Formula:C29H36N6O3Color and Shape:SolidMolecular weight:516.63NLRP3-IN-18
CAS:<p>NLRP3-IN-18, also known as compound 13, is a potent inhibitor of NLRP3, demonstrating an IC50 value of ≤1.0 µM [1].</p>Formula:C19H18ClN3OPurity:98%Color and Shape:SolidMolecular weight:339.82Friluglanstat
CAS:<p>Friluglanstat is an inhibitor of the enzyme prostaglandin E synthase (mPGES-1) and exhibits anti-inflammatory activity [1].</p>Formula:C25H20ClF3N4O3Purity:98%Color and Shape:SolidMolecular weight:516.9NLRP3-IN-22
CAS:<p>NLRP3-IN-22 (Compound II-4) is an inhibitor of NLRP3, exhibiting a 67% inhibition rate at a concentration of 10 μM [1].</p>Formula:C19H12F3NO4SPurity:98%Color and Shape:SolidMolecular weight:407.36OATD-02
CAS:<p>OATD-02 is an orally active, competitive, reversible, noncovalent inhibitor with slow offset kinetics that targets both Arginase1 and 2, exhibiting inhibitory</p>Formula:C12H25BN2O4Purity:98%Color and Shape:SolidMolecular weight:272.15JT002
CAS:<p>JT002 is an orally active NLRP3 inflammasome inhibitor that decreases the production of NLRP3-dependent proinflammatory cytokines (such as IL-1β, IL-1α, IL-18)</p>Formula:C20H24N4O5SPurity:98%Color and Shape:SolidMolecular weight:432.49Nitric oxide production-IN-1
CAS:<p>Nitric oxide production-IN-1 (Compound 1) is an inhibitor of nitric oxide (NO) production extracted from Tupistra chinensis.</p>Formula:C33H52O15Purity:98%Color and Shape:SolidMolecular weight:688.76Glu-urea-Glu-NHS ester
CAS:<p>Compound 21, Glu-urea-Glu-NHS ester, an activated N-hydroxysuccinamide (NHS) ester derivative of Glu-urea-Glu, serves as a pharmacophore for conjugation to prostate specific membrane antigen (PSMA) inhibitors [1].</p>Formula:C27H43N3O11Color and Shape:SolidMolecular weight:585.64CD73-IN-4
CAS:<p>CD73-IN-4 is a potent and selective methylenephosphonic acid CD73 inhibitor</p>Formula:C16H23ClN5O7PPurity:98.61%Color and Shape:SolidMolecular weight:463.81Caspase-3 activator 1
<p>Caspase-3 activator 1 (compound 4b), a Ru(III) metal complex, effectively inhibits gastric tumor growth and metastasis by mediating caspase-3 cleavage.</p>Formula:C28H27N6O2RuS2Purity:98%Color and Shape:SolidMolecular weight:644.75IFN α-IFNAR-IN-1 hydrochloride
CAS:<p>IFN alpha-IFNAR-IN-1 HCl blocks IFN-α/IFNAR binding; IC50 2-8 μM in BM-pDCs' MVA-induced IFN-α response.</p>Formula:C18H18ClNSPurity:99.77%Color and Shape:SolidMolecular weight:315.86ACHP Hydrochloride
CAS:<p>ACHP Hydrochloride (IKK-2 Inhibitor VIII) is a highly potent and selective IKK-β inhibitor with an IC50 of 8.5 nM.</p>Formula:C21H25ClN4O2Purity:99.83%Color and Shape:SolidMolecular weight:400.9ML-090
CAS:<p>ML-090 is NOX1-specific inhibitor(IC50 = 90 nM) which is >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50s >10 μM).</p>Formula:C14H10N4Purity:98.55%Color and Shape:SolidMolecular weight:234.26TLR7 agonist 23
CAS:<p>TLR7 agonist23 (compound 12b) is a potent agonist of Toll-like receptor-7 (TLR7), with an EC50 value of 0.15 uM. It is suitable for research in immune diseases.</p>Formula:C21H22N4O2Color and Shape:SolidMolecular weight:362.42(R)-IL-17 modulator 4
CAS:<p>(R)-IL-17 modulator 4, an R-isomer prodrug of IL-17 modulator 1, is potent and taken orally.</p>Formula:C27H34N6O2Color and Shape:SolidMolecular weight:474.6GBT1118
CAS:<p>GBT1118 is an orally active allosteric modulator of haemoglobin oxygen affinity, enhancing tolerance to acute severe hypoxia and suitable for hypoxia research.</p>Formula:C19H20N2O4Purity:99.69%Color and Shape:SolidMolecular weight:340.37Dimethoxycurcumin
CAS:Dimethoxycurcumin is a stable curcumin analog causing epigenetic shifts in leukemia cells, affecting gene expression.Formula:C23H24O6Purity:99.87%Color and Shape:SolidMolecular weight:396.43h-NTPDase-IN-3
CAS:<p>h-NTPDase-IN-3 is an h-NTPDase inhibitor that inhibits h-NTPDase1, h-NTPDase2, h-NTPDase3 and h-NTPDase8.</p>Formula:C16H10N4SPurity:98.24%Color and Shape:SolidMolecular weight:290.34FEN1-IN-5
CAS:<p>FEN1-IN-5 (compound 12A) is a potent Flap endonuclease-1 (FEN1) inhibitor with an IC50 value of 12 nM, playing a role in DNA repair mechanisms [1].</p>Formula:C21H17N3O4SPurity:98%Color and Shape:SolidMolecular weight:407.44NT-0796
CAS:<p>NT-0796 is an inflammasome NLRP3 inhibitor that inhibits NLRP3 activation.NT-0796 is a potential NDT-19795 delivery vector.</p>Formula:C23H27N3O4Purity:99.67%Color and Shape:SolidMolecular weight:409.48FEN1-IN-7
CAS:<p>FEN1-IN-7 (compound 16), a selective Flap endonuclease-1 (FEN1) inhibitor with an IC50 of 18 nM, plays a role in DNA damage repair in mammalian cells.</p>Formula:C16H14N2O6SPurity:98%Color and Shape:SolidMolecular weight:362.36Fenquinotrione
CAS:<p>Fenquinotrione, a 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor, exhibits IC50 values of 27.2 and 44.7 nM against HPPD from rice and Arabidopsis thaliana</p>Formula:C22H17ClN2O5Color and Shape:SolidMolecular weight:424.83CD38 inhibitor 2
CAS:<p>CD38 inhibitor 2 is a potent CD38 inhibitor ( IC 50 = 0.01 ~ 0.1 μΜ).</p>Formula:C19H24N6O3Color and Shape:SolidMolecular weight:384.43MALT1-IN-7
CAS:<p>MALT1-IN-7 (compound 142b) is a potent inhibitor of MALT1 protease with potential for cancer research.</p>Formula:C19H17F3N8O2SColor and Shape:SolidMolecular weight:478.453'-Azido-3'-deoxy-5-methylcytidine
CAS:<p>3'-Azido-3'-deoxy-5-methylcytidine inhibits HIV-1 reverse transcriptase(EC50 = 0.06 μM) and is an effective inhibitor of xenotropic murine leukemia-related</p>Formula:C10H14N6O4Purity:99.55%Color and Shape:SolidMolecular weight:282.26Keap1-Nrf2-IN-15
CAS:<p>Keap1-Nrf2-IN-15 (Compound 24a) is a potent inhibitor of the Keap1-Nrf2 protein-protein interaction, displaying IC50 values of 77 nM in a fluorescence</p>Formula:C39H35N3O12S2Color and Shape:SolidMolecular weight:801.84
