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Immunology and Inflammation

Immunology and Inflammation

Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.

Subcategories of "Immunology and Inflammation"

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Found 3045 products of "Immunology and Inflammation"

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  • NT-0249
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    NT-0249

    CAS:
    <p>NT-0249 is an inflammatory vesicle NLRP3 inhibitor with anti-inflammatory activity that reverses high-fat diet-induced obesity.</p>
    Formula:C22H28N5NaO4S
    Purity:98.11%
    Color and Shape:Soild
    Molecular weight:481.54

    Ref: TM-T85352

  • BMS-986251
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    BMS-986251

    CAS:
    <p>BMS-986251: Oral RORγt inverse agonist, EC50 12 nM; inhibits IL-17 (EC50 24 nM); effective in mouse psoriasis models.</p>
    Formula:C30H29F8NO5S
    Color and Shape:Solid
    Molecular weight:667.61

    Ref: TM-T40123

  • Histone Modification Compound Library
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    Histone Modification Compound Library

    <p>A unique collection of xnum histone modification related compounds for high throughput screening (HTS) and high content screening (HCS);</p>
    Color and Shape:Odour Solid

    Ref: TM-L3500

  • Iromycin A
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    Iromycin A

    CAS:
    <p>Iromycin A: a bacterial metabolite inhibiting NOS III over NOS I, blocks NADH oxidation, IC50 = 0.461 µM.</p>
    Formula:C19H29NO2
    Color and Shape:Solid
    Molecular weight:303.44

    Ref: TM-T38230

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    BuChE-IN-20

    <p>BuChE-IN-20 is a selective hBuChE inhibitor (IC50= 0.13 μM) with the ability to cross the blood-brain barrier (BBB). This compound, a derivative of L-Tryptophan, exhibits neuroprotective effects by inhibiting nitric oxide (NO) production and reducing reactive oxygen species (ROS) levels. It effectively suppresses the self-aggregation of amyloid-beta (Aβ) peptides and is applicable in Alzheimer's disease research.</p>
    Color and Shape:Odour Solid

    Ref: TM-T206669

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    STING agonist-8 dihydrochloride

    <p>STING Agonist-8 Dihydrochloride (Compound 5-AB) is a highly effective STING agonist, exhibiting an EC50 value of 27 nM in THP1-Dual KI-hSTING-R232 cells.</p>
    Formula:C41H48Cl2N14O4
    Color and Shape:Solid
    Molecular weight:871.82

    Ref: TM-T74328

  • G3-C12
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    G3-C12

    CAS:
    <p>G3-C12 shows anticancer activity. is a galectin-3 binding peptide, with Kd of 88 nM.</p>
    Formula:C74H115N23O23S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1758.99

    Ref: TM-T11346

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    Tri(TLR4-IN-C34-C2-amide-PEG1)-amide-C3-COOH

    <p>Tri(TLR4-IN-C34-C2-amide-PEG1)-amide-C3-COOH, a linker with TLR4-IN-C34, reduces inflammation in mice.</p>
    Formula:C78H125N7O36
    Color and Shape:Solid
    Molecular weight:1736.85

    Ref: TM-T74387

  • 4-ACETAMIDOANTIPYRINE
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    4-ACETAMIDOANTIPYRINE

    CAS:
    <p>4-ACETAMIDOANTIPYRINE, with CAS No. 83-15-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-ACETAMIDOANTIPYRINE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>
    Formula:C13H15N3O2
    Color and Shape:Solid
    Molecular weight:245.28

    Ref: TM-Fr213003

  • VEN-02XX
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    VEN-02XX

    <p>VEN-02XX is an orally active NLRP3 inhibitor capable of penetrating the brain. It effectively suppresses the release of IL-1β and IL-18, with IC50 values of 0.3 and 0.28 μM, respectively. In the 5XFAD/Rubicon KO mouse model, VEN-02XX aids in restoring memory and cognition, inhibits microgliosis, and alleviates neuroinflammation and tau protein pathology. This compound is valuable for Alzheimer's disease (AD) research.</p>
    Formula:C18H16ClF3N4O
    Color and Shape:Solid
    Molecular weight:396.79

    Ref: TM-T207260

  • Inflexuside A
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    Inflexuside A

    CAS:
    <p>Inflexuside A, an abietane diterpenoid from Isodon inflexus, and Inflexuside B inhibit NO in LPS-stimulated RAW264.7 cells.</p>
    Formula:C26H42O9
    Color and Shape:Solid
    Molecular weight:498.61

    Ref: TM-T75616

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    Itolizumab

    CAS:
    <p>Itolizumab (Anti-Human CD6 Recombinant Antibody) is a recombinant anti-CD6 monoclonal antibody that humanizes the extracellular SRCR distal domain 1 of CD6.</p>
    Purity:> 95%
    Color and Shape:Liquid
    Molecular weight:144.82 kDa

    Ref: TM-T76781

  • PS 1145 dihydrochloride
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    PS 1145 dihydrochloride

    CAS:
    <p>IκB kinase (IKK) inhibitor</p>
    Formula:C17H13Cl3N4O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:395.67

    Ref: TM-T23191

  • JPE-1375
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    JPE-1375

    CAS:
    <p>JPE-1375: a C5aR1 antagonist, blocks leukocyte mobilization (EC50=6.9 µM), lowers TNF in mice (EC50=4.5 µM), useful for autoimmune/inflammation research.</p>
    Formula:C49H63FN10O9
    Color and Shape:Solid
    Molecular weight:955.08

    Ref: TM-T74650

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    Tuparstobart

    CAS:
    <p>Tuparstobart (Incagn-02385) is an IgG1κ monoclonal antibody that targets the immune checkpoint receptor protein LAG-3, which is predominantly expressed on</p>
    Color and Shape:Liquid

    Ref: TM-T80918

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    Carotuximab

    CAS:
    <p>Carotuximab (DE-122), an antibody, inhibits CD105 to reduce angiogenesis, inflammation, and tumor growth.</p>
    Purity:> 95%
    Color and Shape:Liquid
    Molecular weight:144.8 kDa

    Ref: TM-T76941

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    Sericin

    <p>Sericin is a globular protein isolated from silkworm cocoons. It has cognitive enhancement and pain-relieving properties. Additionally, Sericin serves as a cryoprotectant, potentially replacing fetal bovine serum or dimethyl sulfoxide (DMSO). It helps reduce oxidative stress and reactive oxygen species (ROS). Sericin aids in wound repair by promoting collagen production and exhibits activities such as antioxidant, antidiabetic, antihyperlipidemic, anti-inflammatory, moisturizing, wound healing promotion, antibacterial, and antitumor effects.</p>
    Color and Shape:Odour Solid

    Ref: TM-TRP-00256

  • Aloenin aglycone
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    Aloenin aglycone

    CAS:
    <p>Aloenin aglycone (compound 13), an inhibitor of NF-κB, can be sourced from aloe exudate.</p>
    Formula:C13H12O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:248.23

    Ref: TM-T79962

  • MAPK Inhibitor Library
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    MAPK Inhibitor Library

    <p>A unique collection of 365 compounds targeting MAPK signaling for drug discovery in MAPK related diseases;</p>
    Color and Shape:Odour Solid

    Ref: TM-L1400

  • β-Aminoarteether
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    β-Aminoarteether

    CAS:
    <p>β-Aminoarteether (SM934 free base), an orally active derivative of Artemisinin, serves a pivotal role in the research of inflammation and autoimmune disorders,</p>
    Formula:C17H29NO5
    Purity:96.09% - 97.02%
    Color and Shape:Solid
    Molecular weight:327.42

    Ref: TM-T38723