Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(136 products)
- CXCR(148 products)
- Cell wall(5 products)
- IL Receptor(112 products)
- IκB/IKK(60 products)
- LTR(3 products)
- MALT(23 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(444 products)
- NOD(17 products)
- NOS(63 products)
- Nrf2(79 products)
- PGE Synthase(31 products)
- ROS(69 products)
- TGF-beta/Smad(58 products)
- TLR(66 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
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Found 3045 products of "Immunology and Inflammation"
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PIC1 PA TFA
<p>PIC1 PATFA is the trifluoroacetate form of PIC1 PA. PIC1 PA TFA is a peptide composed of 15 amino acids and serves as an effective PIC1 analog capable of inhibiting complement activation mediated by the classical pathway.</p>Formula:C71H123N19O21S2·xC2HF3O2Color and Shape:SolidTLQP-21
CAS:<p>TLQP 21, a VGF-derived peptide, guards CGCs against apoptosis and combats early diet-induced diabetes by boosting energy spend.</p>Formula:C107H170N40O26Purity:98%Color and Shape:SolidMolecular weight:2432.75Photosensitizer-4
<p>Compound PS-I (Photosensitizer-4) is an effective photosensitizer that can efficiently kill cancer cells and inhibit tumor growth under light exposure.</p>Color and Shape:Odour SolidAnti-inflammatory agent 59
<p>Anti-inflammatory agent 58 is characterized by its ability to inhibit IL-1β with an IC50 value of 2.28 μM.</p>Color and Shape:Odour SolidEndoplasmic Reticulum Stress Compound Library
<p>A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS);</p>Color and Shape:Odour SolidL-156,602
CAS:<p>L-156,602 has a wide range of applications in life science related research.</p>Formula:C38H64N8O13Color and Shape:SolidMolecular weight:840.973Ziltivekimab
CAS:<p>Ziltivekimab (MEDI 5117) is a CHO-expressed humanized monoclonal antibody targeting IL-6/IFNb2 for use in immune system diseases.</p>Purity:95% - 97.9% (SDS-PAGE); 97.3% (SEC-HPLC)Color and Shape:SoildMelredableukin alfa
CAS:<p>Melredableukin alfa, a human IgG1-κ fused with IL2 mutein, is studied for autoimmune hepatitis and ulcerative colitis.</p>Color and Shape:LiquidKTX-612
CAS:<p>KTX-612 is a compound that serves as an orally active IRAK4 degrader, exhibiting a DC50 value of 7 nM. It is primarily utilized in oncology research [1].</p>Formula:C46H51F3N8O6Color and Shape:SolidMolecular weight:868.94STING-IN-14
CAS:<p>STING-IN-14 is a STING inhibitor with an IC50 of 0.6 nM. It effectively suppresses the activation of the IRF pathway in THP1-DualTM cells. This compound is applicable in research related to autoimmune diseases.</p>Formula:C46H43F2N11O5Color and Shape:SolidMolecular weight:867.901SDH-IN-23
<p>SDH-IN-23 (Compound B21) is an SDH inhibitor with exceptional nematicidal activity. It can suppress nematode feeding, reproduction, and embryonic development while also inducing lethal effects through mechanisms such as oxidative stress, intestinal damage, and SDH inhibition.</p>Formula:C19H11ClF6N2O2Color and Shape:SolidMolecular weight:448.75IKK-IN-3
CAS:<p>IKK-IN-3: potent IKK2 inhibitor (IC50=19nM), affects IKK1(IC50=400nM).</p>Formula:C17H17N5SColor and Shape:SolidMolecular weight:323.42Histamine & Melatonin Receptor-Targeted Compound Library
<p>A unique collection of xnum compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS</p>Color and Shape:Odour SolidSARS-CoV-2-IN-107
<p>SARS-CoV-2-IN-107 (Compound A7) is an inhibitor of SARS-CoV-2 3CLpro, with an IC50 of 261.3 nM. It inhibits the replication of SARS-CoV-2, exhibiting an EC50 of 11.7 μM. Additionally, SARS-CoV-2-IN-107 demonstrates anti-inflammatory activity in LPS-stimulated RAW264.7 macrophages, with a NO inhibition rate of 68.6%.</p>Formula:C15H11FO4Color and Shape:SolidMolecular weight:274.244PROTAC IRAK4 degrader-3
CAS:<p>PROTAC IRAK4 degrader-3 is a PROTAC-induced IRAK4 degrader based on von Hippel-Lindau.</p>Formula:C57H68FN11O8SColor and Shape:SolidMolecular weight:1086.3IL-1β-IN-1
CAS:<p>IL-1β-IN-1, a cannabidiol derivative, acts as a potent inhibitor of IL-1β, exhibiting significant anti-inflammatory and pain relief properties [1].</p>Formula:C22H34O2Color and Shape:SolidMolecular weight:330.5Sacituzumab tirumotecan
CAS:<p>Sacituzumab tirumotecan (SKB264) is an antibody-drug conjugate (ADC) targeting TROP2 (trophoblast cell surface antigen 2), capable of releasing the active payload KL610023 within TROP2-positive tumour cells. an effective topoisomerase I inhibitor that induces DNA damage and leads to cell cycle arrest and apoptosis, for use in non-small cell lung cancer (NSCLC) and triple-negative breast cancer (TNBC).</p>Purity:99%Color and Shape:LiquidPhthalazine
CAS:<p>Compound PDK0135, with CAS No. 253-52-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0135 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formula:C8H6N2Color and Shape:Yellow SolidMolecular weight:130.14TLR8 agonist 7
CAS:<p>TLR8 agonist7 is an agonist of Toll-like receptor 8 (TLR8) with an EC50 of less than 250 nM. It remains stable in human and mouse plasma and induces the secretion of the cytokine TNFα with an EC50 of less than 1 μM. In the MC38-HER2 xenograft mouse model, TLR8 agonist7 demonstrates antitumor activity, achieving a tumor growth inhibition (TGI) rate of 98%.</p>Formula:C54H63N9O16Color and Shape:SolidMolecular weight:1094.13Arginase inhibitor 9
<p>Arginase inhibitor9 (Compound 12a) is a type of arginase enzyme inhibitor with IC50 values of 9 μM for bovine and 55 μM for human arginase I. It also exhibits antioxidant activity by scavenging free radicals. Moreover, Arginase inhibitor9 effectively regulates collagen and procollagen levels, thereby exerting an anti-fibrotic effect.</p>Formula:C13H11NO4SColor and Shape:SolidMolecular weight:277.3
