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Immunology and Inflammation

Immunology and Inflammation

Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.

Subcategories of "Immunology and Inflammation"

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Found 3045 products of "Immunology and Inflammation"

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  • 2-(Phosphonooxy)benzoic acid

    CAS:
    <p>2-(Phosphonooxy)benzoic acid (Fosfosal), used as the anti-inflammatory agent, has the anti-bacterial effect.</p>
    Formula:C7H7O6P
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:218.1
  • Pam3CSK4-Biotin

    CAS:
    <p>Pam3CSK4-Biotin is a biotinylated derivative of Pam3CSK4, functioning as a Toll-like receptor 1/2 (TLR1/2) agonist.</p>
    Formula:C103H192N14O17S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1962.85
  • Phytoene desaturase-IN-1

    CAS:
    <p>Potent PDS inhibitor with Kd of 65.9 μM, induces mRNA reduction and ROS accumulation, useful in agriculture.</p>
    Formula:C18H13ClF3N3O2S
    Color and Shape:Solid
    Molecular weight:427.83
  • Aspulvinone O

    CAS:
    <p>Aspulvinone O, from P. variotti, is an antioxidant with anticancer properties, inhibits GOT1, and reduces SW1990 pancreatic tumor growth in mice.</p>
    Formula:C27H28O6
    Color and Shape:Solid
    Molecular weight:448.515
  • Valeriandoid F

    CAS:
    <p>Valeriandoid F, an iridoid, strongly inhibits NO production (IC50: 0.88 μM) and has anti-inflammatory, antiproliferative effects.</p>
    Formula:C23H34O9
    Color and Shape:Solid
    Molecular weight:454.516
  • CD73-IN-16


    <p>CD73-IN-16 (compound 18) acts as an inhibitor of hCD73, exhibiting an IC50 value of 0.28 μM.</p>
    Color and Shape:Odour Solid
  • NLRP3-IN-46


    <p>NLRP3-IN-46 (Compound 3k) activates the cholinergic anti-inflammatory pathway involved in neuro-immune modulation, thereby inhibiting the activation of the NLRP3 inflammasome. Furthermore, NLRP3-IN-46 suppresses the production of IL-1β in THP-1 cells induced by Uric acid sodium, making it relevant for research in gouty arthritis.</p>
    Color and Shape:Odour Solid
  • Feeblin

    CAS:
    <p>Feeblin (IRF5-IN-1) induces protein degradation, inhibits pro-inflammatory pathways, and is used for autoimmune disease research.</p>
    Formula:C27H33N3O2
    Purity:99.58% - 99.88%
    Color and Shape:Soild
    Molecular weight:431.57
  • Anticancer agent 15

    CAS:
    <p>Anticancer agent 15 raises ROS, causing necroptosis in melanoma cells.</p>
    Formula:C35H40Cl2N2O5
    Color and Shape:Solid
    Molecular weight:639.61
  • ZM640


    <p>ZM640 is an NLRP3 inhibitor that promotes IL-1β release mediated by NLRP3 inflammasome activation in THP-1 cells. It demonstrates low cytotoxicity.</p>
    Formula:C28H36F3NO8S
    Molecular weight:603.21137
  • COX-2/15-LOX-IN-2


    <p>COX-2/15-LOX-IN-2 is a potent inhibitor of both COX-2 and 15-LOX, demonstrating IC50 values of 0.065 μM for COX-2 and 1.86 μM for 15-LOX.</p>
    Formula:C27H26N6OS2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:514.66
  • Huangjiangsu A

    CAS:
    <p>Huangjiangsu A, from D. villosa, may protect the liver from H2O2 damage and reduce ROS, showing therapeutic promise.</p>
    Formula:C51H82O22
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1047.18
  • KTX-951

    CAS:
    <p>KTX-951, a PROTAC, degrades IRAK4 (DC50=18 nM), 22% oral bioavailability in rats, shows promise as anticancer agent.</p>
    Formula:C46H52F2N8O6
    Color and Shape:Solid
    Molecular weight:850.95
  • BTH1704


    <p>BTH1704 is a human monoclonal antibody targeting MUC1. It facilitates the killing of iC3b-opsonized tumor cells by leukocytes triggered by PGG. BTH1704 is applicable in studies on pancreatic cancer and breast cancer.</p>
    Color and Shape:Odour Liquid
  • MAO-B-IN-39


    <p>MAO-B-IN-39 (compound11) is a potent inhibitor of monoamine oxidase B (MAO-B), with an IC50 of 3.61 μM. It demonstrates strong NRF2 induction capabilities and exhibits significant anti-inflammatory and neuroprotective effects in oxidative stress-related in vitro models. Additionally, MAO-B-IN-39 shows high liver microsomal stability and favorable pharmacokinetic properties in mice, making it a valuable compound for Parkinson's disease research.</p>
    Formula:C17H13FN2O
    Color and Shape:Solid
    Molecular weight:280.3
  • Olendalizumab

    CAS:
    <p>Olendalizumab (ALXN1007) is a humanized antibody targeting C5a for research on COVID-19-related inflammation.</p>
    Color and Shape:Liquid
  • PROTAC STING Degrader-1

    CAS:
    <p>PROTAC STING Degrader-1 (Compound SP23) is a STING-targeted PROTAC degrader exhibiting a DC50 of 3.2 μM and demonstrates anti-inflammatory activity [1].</p>
    Formula:C34H33N7O10
    Color and Shape:Solid
    Molecular weight:699.67
  • FITC-labeled ODN 2088 sodium


    <p>FITC-labeled ODN 2088 (sodium) serves as a potent inhibitor of TLR3, TLR7, and TLR9, and is utilized to assess CpG ODN cellular uptake and localization</p>
    Color and Shape:Odour Solid
  • NF-κΒ activator 1

    CAS:
    <p>NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.</p>
    Formula:C16H11FN2O2S
    Purity:99.58%
    Color and Shape:Solid
    Molecular weight:314.33
  • Melredableukin alfa

    CAS:
    <p>Melredableukin alfa, a human IgG1-κ fused with IL2 mutein, is studied for autoimmune hepatitis and ulcerative colitis.</p>
    Color and Shape:Liquid