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Immunology and Inflammation

Immunology and Inflammation

Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.

Subcategories of "Immunology and Inflammation"

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Found 3054 products of "Immunology and Inflammation"

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  • NOD1 antagonist-1


    <p>NOD1antagonist-1 (compound 37) acts as an antagonist to NOD1 and exhibits a slight selectivity between NOD1 and NOD2, with IC50 values of 9.18 μM and 20.8 μM, respectively.</p>
    Formula:C24H32N4O2S
    Molecular weight:440.2246
  • Polyinosinic acid

    CAS:
    <p>Polyinosinic acid: single-strand, TLR3 agonist, boosts immune response, has immune regulation uses.</p>
    Formula:(C10H13N4O8P)x
    Color and Shape:Solid
  • TLR8 agonist 2 hydrochloride

    CAS:
    <p>TLR8 agonist 2 hydrochloride: potent for human TLR8 (EC50 3 nM), weak for TLR7 (EC50 33.33 μM).</p>
    Formula:C16H22N8·xHCl
    Color and Shape:Solid
  • Pegaldesleukin

    CAS:
    <p>Pegaldesleukin, a PEG-IL2 conjugate, exhibits antiviral properties, potentially slowing HIV progression, preserving immune function.</p>
    Color and Shape:Liquid
  • Anticonvulsant agent 10


    <p>Anticonvulsant agent 10 (Compound 6d) is an inhibitor targeting the Keap1-Nrf2 interaction, with a strong activity showing an ED50 of 0.04 mmol/kg. By inhibiting the Keap1-Nrf2 binding, it activates the Nrf2/ARE pathway, providing anticonvulsant and neuroprotective effects, making it useful for research in epilepsy and neuroprotection.</p>
    Color and Shape:Odour Solid
  • D-NAME (hydrochloride)

    CAS:
    <p>D-NAME, a less active NO synthase inhibitor enantiomer, has mild cardiovascular effects in rats; inactive in mouse nociception.</p>
    Formula:C7H16ClN5O4
    Color and Shape:Solid
    Molecular weight:269.69
  • Antiviral agent 38

    CAS:
    <p>(6R)-6-Tert-butyl-10-(3-methoxypropoxy)-dihydro-2-oxo-indazole carboxylic acid has antiviral and antibacterial properties, useful for Hepatitis B research.</p>
    Formula:C23H27N3O5
    Purity:99.66%
    Color and Shape:Soild
    Molecular weight:425.48
  • KYN-101

    CAS:
    <p>KYN-101 is an and aryl hydrocarbon receptor (AHR) inhibitor with anticancer activity. KYN-101 is used for the study of breast cancer and acute myeloid leukemia.</p>
    Formula:C22H19FN6
    Purity:98.35%
    Color and Shape:Solid
    Molecular weight:386.43
  • Vemircopan

    CAS:
    <p>Vemircopan is a complement factor D inhibitor.</p>
    Formula:C29H28BrN7O3
    Color and Shape:Solid
    Molecular weight:602.493
  • cGAMP disodium

    CAS:
    <p>cGAMP disodium, a bacterial CDN, boosts interferon production and activates STING, enhancing immune responses as a sublingual adjuvant.</p>
    Formula:C20H24N10O13P2·2Na
    Color and Shape:Soild
    Molecular weight:720.39
  • Ara-F-NAD+

    CAS:
    <p>Ara-F-NAD+, an arabino analogue of NAD + , is a potent, slow-binding CD38 NADase inhibitor, with a K i of 169 nM.</p>
    Formula:C21H26FN7O13P2
    Color and Shape:Solid
    Molecular weight:665.421
  • Anti-inflammatory agent 36

    CAS:
    <p>Anti-inflammatory compound inhibits TNF-a/IL-6 in mouse macrophages; IC50=3.69/3.68uM.</p>
    Formula:C25H27NO7
    Purity:99.85%
    Color and Shape:Soild
    Molecular weight:453.48
  • Flunixin

    CAS:
    <p>Flunixin is a nonsteroidal anti-inflammatory drug (NSAID), antipyretic, and analgesic used in pigs, horses, and cattle.</p>
    Formula:C14H11F3N2O2
    Color and Shape:Solid
    Molecular weight:296.24
  • Valeriandoid F

    CAS:
    <p>Valeriandoid F, an iridoid, strongly inhibits NO production (IC50: 0.88 μM) and has anti-inflammatory, antiproliferative effects.</p>
    Formula:C23H34O9
    Color and Shape:Solid
    Molecular weight:454.516
  • 2-Aminoquinoline

    CAS:
    <p>Compound Fr16621, with CAS No. 580-22-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr16621 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>
    Formula:C9H8N2
    Color and Shape:Light Yellow Crystals
    Molecular weight:144.18
  • COX-2/15-LOX-IN-2


    <p>COX-2/15-LOX-IN-2 is a potent inhibitor of both COX-2 and 15-LOX, demonstrating IC50 values of 0.065 μM for COX-2 and 1.86 μM for 15-LOX.</p>
    Formula:C27H26N6OS2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:514.66
  • Phytoene desaturase-IN-1

    CAS:
    <p>Potent PDS inhibitor with Kd of 65.9 μM, induces mRNA reduction and ROS accumulation, useful in agriculture.</p>
    Formula:C18H13ClF3N3O2S
    Color and Shape:Solid
    Molecular weight:427.83
  • Feeblin

    CAS:
    <p>Feeblin (IRF5-IN-1) induces protein degradation, inhibits pro-inflammatory pathways, and is used for autoimmune disease research.</p>
    Formula:C27H33N3O2
    Purity:99.58% - 99.88%
    Color and Shape:Soild
    Molecular weight:431.57
  • PROTAC STING Degrader-1

    CAS:
    <p>PROTAC STING Degrader-1 (Compound SP23) is a STING-targeted PROTAC degrader exhibiting a DC50 of 3.2 μM and demonstrates anti-inflammatory activity [1].</p>
    Formula:C34H33N7O10
    Color and Shape:Solid
    Molecular weight:699.67
  • NF-κΒ activator 1

    CAS:
    <p>NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.</p>
    Formula:C16H11FN2O2S
    Purity:99.58%
    Color and Shape:Solid
    Molecular weight:314.33