NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
Found 398 products of "NF-κB"
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Ginsenoside Rg2
CAS:Ginsenoside Rg2 (Chikusetsusaponin I) is one of the major active components of ginseng, act as an NF-κB inhibitor.Formula:C42H72O13Purity:99.77% - 99.78%Color and Shape:SolidMolecular weight:785.01Ref: TM-T2873
2mg37.00€5mg52.00€10mg88.00€25mg131.00€50mg188.00€100mg279.00€500mg658.00€1mL*10mM (DMSO)87.00€Dehydrodiisoeugenol
CAS:Dehydrodiisoeugenol suppresses COX-2 expression and NF-κB activity, reducing inflammation in LPS-stimulated murine macrophages.Formula:C20H22O4Purity:99.97%Color and Shape:SolidMolecular weight:326.39Stachydrine Hydrochloride
CAS:Stachydrine Hydrochloride is an effective component that mainly extracted from the leaf of Leonurussibiricus.Formula:C7H14ClNO2Purity:99.53% - 99.71%Color and Shape:Light Yellow PasteMolecular weight:179.64Ginsenoside Rg1
CAS:Ginsenoside Rg1 (Panaxoside Rg1) is a class of steroid glycosides, and triterpene saponins found exclusively in the plant genus Panax (ginseng).Formula:C42H72O14Purity:99% - 99.92%Color and Shape:White Crystalline PowderMolecular weight:801.01CBL0137 hydrochloride
CAS:CBL0137 hydrochloride (Curaxin-137 hydrochloride) is an inhibitor of the histone chaperone FACT, which also activates p53 and inhibits NF-κB.Cost-effective and quality-assured.Formula:C21H25ClN2O2Purity:99.35% - 99.86%Color and Shape:SolidMolecular weight:372.88Kaempferol-3-O-glucorhamnoside
CAS:Kaempferol-3-O-glucorhamnoside (Kaempferol 3-glucorhamnoside), a flavonoid derived from plant Thesium chinense Turcz, inhibits inflammatory responses via MAPKFormula:C27H30O15Purity:96.96% - 98.17%Color and Shape:SolidMolecular weight:594.5Ref: TM-T5S0089
1mg48.00€5mg92.00€10mg136.00€25mg215.00€50mg323.00€100mg469.00€200mg647.00€1mL*10mM (DMSO)122.00€Saikosaponin D
CAS:Saikosaponin D is a novel SERCA inhibitor by inhibiting NF-κB and STAT3 signaling to protect against acetaminophen-induced hepatotoxicity.Formula:C42H68O13Purity:98.34% - 99.73%Color and Shape:White PowderMolecular weight:780.98IMD-0354
CAS:IMD-0354 (IKK2 Inhibitor V) is an IKKβ inhibitor and inhibits IκBα phosphorylation in NF-κB pathway.Formula:C15H8ClF6NO2Purity:99.65% - 99.98%Color and Shape:SolidMolecular weight:383.67Ref: TM-T6141
2mg46.00€5mg63.00€10mg87.00€25mg155.00€50mg210.00€100mg294.00€500mg713.00€1mL*10mM (DMSO)65.00€Phellodendrine
CAS:Phellodendrine may treat nephritis by blocking macrophage and T cell activity in glomeruli.Formula:C20H24NO4Purity:98.7% - 99.94%Color and Shape:SolidMolecular weight:342.41Ref: TM-T6S0781
2mg40.00€5mg56.00€10mg80.00€25mg114.00€50mg167.00€100mg240.00€200mg355.00€1mL*10mM (DMSO)73.00€Muscone
CAS:Muscone (3-Methylcyclopentadecanone) is an organic compound that is the primary contributor to the odor of musk.Formula:C16H30OPurity:98.97% - ≥98%Color and Shape:Colourless Liquid LiquidMolecular weight:238.41BOT-64
CAS:BOT-64 is an IKK-2 inhibitor which targets the Ser177 and/or Ser181 residues in the kinase's activation loop domain.BOT-64 is a cell-permeable benzoxathioleFormula:C15H15NO2SPurity:99.73%Color and Shape:SolidMolecular weight:273.35Ref: TM-T8705
1mg50.00€5mg110.00€10mg170.00€25mg323.00€50mg494.00€100mg665.00€200mg893.00€1mL*10mM (DMSO)102.00€Flaconitine
CAS:Flaconitine (Acetylaconitine) is an NF-κB inhibitor and an alkaloid.
Formula:C36H49NO12Purity:98% - 99.84%Color and Shape:SolidMolecular weight:687.773'-Sialyllactose
CAS:3'-Sialyllactose (3'-SL), a prebiotic, supports immunity, reduces inflammation and arthritis, and is low-toxicity for research.Formula:C23H39NO19Color and Shape:SolidMolecular weight:633.55EUK-134
CAS:EUK-134, a synthetic SOD/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril.Formula:C18H18ClMnN2O4Purity:98.39%Color and Shape:SolidMolecular weight:416.74Morusin
CAS:Morusin shows anti-tumor, antioxidant, and anti-inflammatory properties by inhibiting STAT3, NFκB, and inducing apoptosis.Formula:C25H24O6Purity:98.68% - 99.8%Color and Shape:SolidMolecular weight:420.45QNZ
CAS:QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.Formula:C22H20N4OPurity:99.17% - 99.18%Color and Shape:White SolidMolecular weight:356.42Ref: TM-T6204
1mg43.00€2mg57.00€5mg93.00€10mg140.00€25mg188.00€50mg329.00€100mg490.00€200mg710.00€1mL*10mM (DMSO)93.00€BMS-345541
CAS:BMS-345541 (IKK Inhibitor III) is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM, respectively.Formula:C14H17N5Purity:99.36% - 99.74%Color and Shape:SolidMolecular weight:255.32Myrislignan
CAS:Myrislignan exhibits anti-inflammatory, anti-cancer properties, hinders NF-κB pathway, curbs A549 cell growth, and triggers apoptosis and cell cycle arrest.
Formula:C21H26O6Purity:98.77% - 99.41%Color and Shape:SolidMolecular weight:374.43IRAK-4 protein kinase inhibitor 2
CAS:IRAK-4 protein kinase inhibitor 2 is a potent interleukin-1 receptor-associated kinase-4 (IRAK-4) inhibitor(IC50 = 4 μM).Formula:C14H10N4O3Purity:99.5%Color and Shape:SolidMolecular weight:282.25NF-κB-IN-1
CAS:NF-κB-IN-1 (1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)-) is a potent NF-κB signaling pathwayFormula:C31H30O8Purity:99.03%Color and Shape:SolidMolecular weight:530.57Ref: TM-T9105
1mg166.00€5mg341.00€10mg550.00€25mg898.00€50mg1,216.00€100mg1,644.00€1mL*10mM (DMSO)398.00€Laquinimod
CAS:Laquinimod (LAQ) is an effective immunomodulator, which is currently under development in phase III trials for the treatment of multiple sclerosis as an oral
Formula:C19H17ClN2O3Purity:98.42% - 98.84%Color and Shape:SolidMolecular weight:356.8Sulindac sodium
CAS:Sulindac (sodium) (MK-231) is an NSAID used for arthritis pain, swelling, gout, and as an immunomodulator in CRC therapy.Formula:C20H16FNaO3SColor and Shape:SolidMolecular weight:378.39Articaine
CAS:Articaine (Hoe-045 free base), an amide anesthetic featuring an ester group, effectively relieves pain by reversibly binding to the α-subunit of the voltage-Formula:C13H20N2O3SColor and Shape:SolidMolecular weight:284.372,5-Dihydroxyacetophenone
CAS:2,5-Dihydroxyacetophenone has anti-anxiety, neuroprotective, anti-inflammatory properties, and modulates cell signaling and melanogenesis.Formula:C8H8O3Purity:99.75%Color and Shape:Yellow PowderMolecular weight:152.152-Hydroxychalcone
CAS:2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated. It inhibits invasion of breast cancer cells.Formula:C15H12O2Purity:99.6%Color and Shape:SolidMolecular weight:224.25Ginsenoside Rd
CAS:Ginsenoside Rd (Gypenoside VIII) may have properties that inhibit or prevent the growth of tumors.Formula:C48H82O18Purity:99.13% - 99.92%Color and Shape:SolidMolecular weight:947.15Ref: TM-T2878
1mg37.00€5mg71.00€10mg99.00€25mg170.00€50mg260.00€100mg394.00€200mg570.00€1mL*10mM (DMSO)124.00€Isoquercetin
CAS:1.Formula:C21H20O12Purity:98.08% - 99.76%Color and Shape:SolidMolecular weight:464.38Ref: TM-T5S0754
5mg46.00€10mg58.00€25mg92.00€50mg137.00€100mg200.00€200mg295.00€1mL*10mM (DMSO)49.00€Berbamine
CAS:Berbamine is a natural product extracted from Phellodendron amurense.Formula:C37H40N2O6Purity:98.92% - 99.67%Color and Shape:White Crystal PowderMolecular weight:608.72Dauricine
CAS:1.Formula:C38H44N2O6Purity:99.24% - 99.75%Color and Shape:White PowderMolecular weight:624.77Dendrophenol
CAS:Dendrophenol (Moscatilin) is a natural product isolated from the stem of Dendrobium loddigesii Rolfe, act as a NF-κB inhibitor. Antineoplastic activity.Formula:C17H20O5Purity:98.2% - 99.36%Color and Shape:SolidMolecular weight:304.34Ref: TM-T3S1707
1mg99.00€2mg138.00€5mg215.00€10mg319.00€25mg530.00€50mg755.00€100mg1,018.00€1mL*10mM (DMSO)234.00€SC-514
CAS:SC-514 (GK 01140) is a selective, orally active, ATP-competitive IKK-2 inhibitor (IC50=11.2±4.7 μM), obstructs NF-κB-dependent gene expression.
Formula:C9H8N2OS2Purity:99.88% - >99.99%Color and Shape:SolidMolecular weight:224.3yangonin
CAS:Yangonin (Y100550) is a novel CB1 receptor ligand with affinity for human recombinant CB1 receptors.Formula:C15H14O4Purity:98.82% - 99.55%Color and Shape:Pale Yellow PowderMolecular weight:258.27Ref: TM-T3S0738
1mg70.00€5mg135.00€10mg207.00€25mg349.00€50mg515.00€100mg735.00€1mL*10mM (DMSO)177.00€Iron sucrose
CAS:Iron sucrose (Sucroferric oxyhydroxide) is treatment of iron deficiency anemia.
Formula:C18H24Fe2O24Purity:99.97%Color and Shape:SolidMolecular weight:736.1Neochlorogenic acid
CAS:Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.Formula:C16H18O9Purity:99.12% - 99.54%Color and Shape:White PowderMolecular weight:354.31Ref: TM-T6S1538
1mg34.00€5mg71.00€10mg90.00€25mg147.00€50mg208.00€100mg309.00€200mg447.00€1mL*10mM (DMSO)77.00€Triacetylresveratrol
CAS:Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity, it inhibits the phosphorylation of STAT3 and NFκB in pancreatic cancer cells.
Formula:C20H18O6Purity:99.81%Color and Shape:Off White PowderMolecular weight:354.35Micheliolide
CAS:Micheliolide(MCL) is a sesquiterpene lactone which inhibits various inflammatory response.Formula:C15H20O3Purity:98% - 99.37%Color and Shape:SolidMolecular weight:248.32Ref: TM-T5688
1mg44.00€5mg113.00€10mg177.00€25mg299.00€50mg447.00€100mg623.00€500mg1,305.00€1mL*10mM (DMSO)124.00€Licochalcone D
CAS:Licochalcone D may treat melanoma and heart injury, halt cell spread, and reduce inflammation and allergies.Formula:C21H22O5Purity:99.03% - 99.9%Color and Shape:SolidMolecular weight:354.4Nitidine chloride
CAS:1.Formula:C21H18ClNO4Purity:96.59% - 99.55%Color and Shape:SolidMolecular weight:383.82Rhoifolin
CAS:Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.Formula:C27H30O14Purity:98.11% - 98.58%Color and Shape:SolidMolecular weight:578.52Ginsenoside Rb1
CAS:Ginsenoside Rb1 (Gypenoside Ⅲ) is part of a class of steroid glycosides; may have properties that inhibit or prevent the growth of tumors.Formula:C54H92O23Purity:99.12% - 99.76%Color and Shape:SolidMolecular weight:1109.29Convallatoxin
CAS:Convallatoxin is a natural product.Formula:C29H42O10Purity:99.27% - 99.53%Color and Shape:Prisms From Methanol + Ether SolidMolecular weight:550.64Cornuside
CAS:Cornuside boosts immunity, reduces inflammation, protects heart and liver, and guards against brain injury by modulating stress responses.Formula:C24H30O14Purity:99.86% - >99.99%Color and Shape:SolidMolecular weight:542.49Ref: TM-T4S2326
1mg96.00€5mg264.00€10mg415.00€25mg677.00€50mg935.00€100mg1,254.00€500mg2,527.00€1mL*10mM (DMSO)315.00€Bortezomib
CAS:Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.Formula:C19H25BN4O4Purity:97.79% - >99.99%Color and Shape:Yellow SolidMolecular weight:384.24Ref: TM-T2399
5mg50.00€10mg60.00€25mg75.00€50mg92.00€100mg137.00€200mg213.00€500mg353.00€1mL*10mM (DMSO)50.00€Benzoyloxypaeoniflorin
CAS:Benzoyloxypaeoniflorin, a natural compound, enhances blood flow by inhibiting platelet aggregation and coagulation.Formula:C30H32O13Purity:98.52% - 99.96%Color and Shape:SolidMolecular weight:600.57Ref: TM-T4S1658
1mg120.00€5mg281.00€10mg409.00€25mg660.00€50mg888.00€100mg1,224.00€1mL*10mM (DMSO)358.00€Pyrrolidinedithiocarbamate ammonium
CAS:Pyrrolidinedithiocarbamate ammonium (1-Pyrrolidinedithiocarboxylic acid ammonium salt), a selective NF-κB inhibitor, inhibits translation of nitric oxideFormula:C5H12N2S2Purity:98% - >99.99%Color and Shape:Off-White To Pale Yellow CrystalsMolecular weight:164.29Sodium Aescinate
CAS:Sodium Aescinate (Escin sodium salt) is extracted from Aesculus wilsonii.Formula:C54H83NaO23Purity:95.17%Color and Shape:SolidMolecular weight:1123.21Specnuezhenide
CAS:Specnuezhenide (Nuezhenide) is isolated from the fruit of Ligustrum lucidum. It inhibits NF-κB and wnt/β-catenin signaling.Cost-effective and quality-assured.Formula:C31H42O17Purity:98% - 99.93%Color and Shape:SolidMolecular weight:686.66Ref: TM-T3803
2mg34.00€5mg50.00€10mg80.00€25mg152.00€50mg219.00€100mg319.00€200mg474.00€1mL*10mM (DMSO)77.00€γ-Tocotrienol
CAS:γ-Tocotrienol (Plastochromanol) is one of the four types of tocotrienol, a type of vitamin E.Formula:C28H42O2Purity:97.27% - 98.13%Color and Shape:SolidMolecular weight:410.63Ref: TM-T19768
1mg44.00€2mg58.00€5mg96.00€10mg137.00€25mg224.00€50mg333.00€100mg489.00€200mg705.00€1mL*10mM (DMSO)92.00€Ginsenoside Rk3
CAS:Ginsenosides Rk3 & Rh4 may treat inflammation and ischemic heart disease.Formula:C36H60O8Purity:99.88%Color and Shape:SolidMolecular weight:620.86Ref: TM-T6S1495
1mg85.00€5mg172.00€10mg255.00€25mg426.00€50mg630.00€100mg898.00€1mL*10mM (DMSO)283.00€MLN120B
CAS:MLN120B is a selective and ATP competitive IKKβ inhibitor (IC50: 60 nM).Formula:C19H15ClN4O2Purity:98.92%Color and Shape:SolidMolecular weight:366.8Ref: TM-TQ0306
1mg49.00€2mg70.00€5mg96.00€10mg160.00€25mg329.00€50mg567.00€100mg777.00€1mL*10mM (DMSO)116.00€
