CymitQuimica logo
JAK/STAT signaling

JAK/STAT signaling

JAK/STAT signaling inhibitors are compounds that disrupt the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway, which is involved in cytokine signaling, cell growth, and immune response. These inhibitors are important tools in studying the regulation of this pathway and its role in various diseases, including cancers, immune disorders, and inflammatory conditions. JAK/STAT inhibitors are also being developed as targeted therapies for these diseases. At CymitQuimica, we provide a wide selection of high-quality JAK/STAT signaling inhibitors to support your research in molecular biology, oncology, and immunology.

Subcategories of "JAK/STAT signaling"

Found 321 products of "JAK/STAT signaling"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • Brevilin A
    Targetmol
    + Info

    Brevilin A

    CAS:
    <p>Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.</p>
    Formula:C20H26O5
    Purity:99.97% - >99.99%
    Color and Shape:Solid
    Molecular weight:346.42

    Ref: TM-T4672

  • WDR5-0103 hydrochloride[890190-22-4(free base)]
    Targetmol
    + Info

    WDR5-0103 hydrochloride[890190-22-4(free base)]

    <p>WDR5-0103 hydrochloride[890190-22-4(free base)] (WD-Repeat Protein 5-0103) is an effective and specific WD repeat-containing protein 5 (WDR5) antagonist (Kd:</p>
    Formula:C21H26ClN3O4
    Purity:99.66%
    Color and Shape:Solid
    Molecular weight:419.9

    Ref: TM-T5140

  • Ritlecitinib tosylate
    Targetmol
    + Info

    Ritlecitinib tosylate

    CAS:
    <p>Ritlecitinib (PF-06651600) is a potent, selective JAK3 inhibitor with proven in vivo efficacy, low clearance, and has undergone clinical trials.</p>
    Formula:C22H27N5O4S
    Color and Shape:Solid
    Molecular weight:457.549

    Ref: TM-T69822

  • AZ960
    Targetmol
    + Info

    AZ960

    CAS:
    <p>AZ960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: &lt;3 nM and0.45 nM).</p>
    Formula:C18H16F2N6
    Purity:96.02% - 98.51%
    Color and Shape:Solid
    Molecular weight:354.36

    Ref: TM-T6309

  • Cerdulatinib
    Targetmol
    + Info

    Cerdulatinib

    CAS:
    <p>Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.</p>
    Formula:C20H27N7O3S
    Purity:98.74% - 99.49%
    Color and Shape:Solid
    Molecular weight:445.54

    Ref: TM-T2487

  • Upadacitinib
    Targetmol
    + Info

    Upadacitinib

    CAS:
    <p>Upadacitinib (ABT-494), a selective JAK1 inhibitor, is researched for autoimmune diseases; IC50: 43 nM.</p>
    Formula:C17H19F3N6O
    Purity:98.96% - 99.94%
    Color and Shape:Solid
    Molecular weight:380.37

    Ref: TM-T7503

  • Atractylenolide I
    Targetmol
    + Info

    Atractylenolide I

    CAS:
    <p>Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to paclitaxel.</p>
    Formula:C15H18O2
    Purity:97.55% - 99.92%
    Color and Shape:Solid
    Molecular weight:230.3

    Ref: TM-T5S0167

  • CX-6258 hydrochloride
    Targetmol
    + Info

    CX-6258 hydrochloride

    CAS:
    <p>CX-6258 hydrochloride (Pim-Kinase Inhibitor X) is an effective, orally efficacious Pim1/2/3 kinase inhibitor (IC50: 5/25/16 nM).</p>
    Formula:C26H24ClN3O3·HCl
    Purity:96.03% - 98.60%
    Color and Shape:Solid
    Molecular weight:498.4

    Ref: TM-T6148

  • Cerdulatinib hydrochloride
    Targetmol
    + Info

    Cerdulatinib hydrochloride

    CAS:
    <p>Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 &lt; 200 nM.</p>
    Formula:C20H28ClN7O3S
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:482

    Ref: TM-T6104

  • GS-829845
    Targetmol
    + Info

    GS-829845

    CAS:
    <p>GS-829845 is a JAK1 inhibitor, the main component of the active metabolite of Filgotinib, which is approximately 10-fold less potent and has a longer half-life</p>
    Formula:C17H19N5O2S
    Purity:99.93%
    Color and Shape:Solid
    Molecular weight:357.43

    Ref: TM-T67905

  • Golotimod
    Targetmol
    + Info

    Golotimod

    CAS:
    <p>Golotimod (SCV 07) is an antimicrobial active dipeptide with immunomodulatory activity for the study of recurrent genital herpes simplex virus 2 infections.</p>
    Formula:C16H19N3O5
    Purity:99.88% - 99.98%
    Color and Shape:Solid
    Molecular weight:333.34

    Ref: TM-T11449L

  • NVP-BSK805
    Targetmol
    + Info

    NVP-BSK805

    CAS:
    <p>NVP-BSK805 (BSK 805) is an ATP-competitive JAK2 inhibitor.</p>
    Formula:C27H28F2N6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:490.55

    Ref: TM-T5049

  • CymitQuimica logo
    Targetmol
    + Info

    Solrikitug

    CAS:
    <p>Solrikitug,Anti-CRLF2 humanized IgG1κ monoclonal antibody.</p>
    Purity:95%
    Color and Shape:Liquid

    Ref: TM-T9901A-527

  • TLC1566-0618
    Targetmol
    + Info

    TLC1566-0618

    CAS:
    <p>TLC1566-0618 shows antitumor activity and targets stat.</p>
    Formula:C20H15NO3S3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:413.53

    Ref: TM-T121011

  • (3S,4S)-Tofacitinib
    Targetmol
    + Info

    (3S,4S)-Tofacitinib

    CAS:
    <p>(3S,4S)-Tofacitinib, a less active enantiomer of tofacitinib, is a Janus kinases inhibitor.</p>
    Formula:C16H20N6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:312.37

    Ref: TM-T13426L

  • Golotimod TFA
    Targetmol
    + Info

    Golotimod TFA

    CAS:
    <p>Golotimod TFA (SCV 07 TFA) is a dipeptide exhibiting immunomodulatory and antibacterial activity, alleviates radiation-induced oral mucositis.</p>
    Formula:C18H20F3N3O7
    Purity:98%
    Color and Shape:Soild
    Molecular weight:447.36

    Ref: TM-T11449L2

  • ZM39923
    Targetmol
    + Info

    ZM39923

    CAS:
    <p>ZM39923 is a JAK3 inhibitor (pIC50: 7.1). ZM39923 also effectively inhibits tissue transglutaminase (IC50: 10 nM).</p>
    Formula:C23H25NO
    Purity:98%
    Color and Shape:Solid
    Molecular weight:331.45

    Ref: TM-T17295

  • SD-1029
    Targetmol
    + Info

    SD-1029

    CAS:
    <p>SD-1029 is a JAK2 inhibitor and a novel Stat3 activation inhibitor that inhibits Stat3 phosphorylation and JAK-STAT signaling.</p>
    Formula:C25H32Br2Cl2N2O3
    Color and Shape:Solid
    Molecular weight:639.25

    Ref: TM-T24774

  • K00135
    Targetmol
    + Info

    K00135

    CAS:
    <p>K00135 (IMIDAZOPYRIDAZIN 1) is a selective inhibitor of Pim kinases and can be used in studies about gastric cancer and antileukemic therapeutics.</p>
    Formula:C18H18N4O
    Purity:98.16%
    Color and Shape:Solid
    Molecular weight:306.36

    Ref: TM-T27704

  • JAK-IN-11
    Targetmol
    + Info

    JAK-IN-11

    CAS:
    <p>JAK-IN-11 (R-348) is a potent and selective inhibitor of JAK, has the potential for the skin disorders treatment.</p>
    Formula:C23H22FN5O4S
    Purity:99.75%
    Color and Shape:Solid
    Molecular weight:483.52

    Ref: TM-T12549