JAK/STAT signaling

JAK/STAT signaling inhibitors are compounds that disrupt the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway, which is involved in cytokine signaling, cell growth, and immune response. These inhibitors are important tools in studying the regulation of this pathway and its role in various diseases, including cancers, immune disorders, and inflammatory conditions. JAK/STAT inhibitors are also being developed as targeted therapies for these diseases. At CymitQuimica, we provide a wide selection of high-quality JAK/STAT signaling inhibitors to support your research in molecular biology, oncology, and immunology.

Read more

Subcategories of "JAK/STAT signaling"

JAK

Pim

STAT

Products of "JAK/STAT signaling"

20
- 50
- 100
- 200

products per page. 178 products on this category.

Brand	Product data	Purity	Price range	Estimated delivery
	JAK1-IN-16 REF: TM-T201648	- - -	To inquire	Tue 03 Jun 25
	JAK2-IN-11 REF: TM-T201601CAS: 3057053-17-2	- - -	To inquire	Tue 03 Jun 25
	JAK3-IN-7 REF: TM-T10009CAS: 1263774-57-7	98.81%	665.00 €~1,710.00 €	Tue 03 Jun 25
	AZ-3 REF: TM-T10424CAS: 2228908-91-4	98%	1,561.00 €~4,370.00 €	Tue 03 Jun 25
	JBJ-02-112-05 REF: TM-T11713CAS: 2748162-29-8	98%	907.00 €~2,375.00 €	Tue 03 Jun 25
	Londamocitinib REF: TM-T11706CAS: 2241039-81-4	99.47%	180.00 €~1,568.00 €	Tue 03 Jun 25
	JDTic dihydrochloride REF: TM-T11721LCAS: 785835-79-2	98%	62.00 €~1,225.00 €	Tue 03 Jun 25
	GDC-0339 REF: TM-T15376CAS: 1428569-85-0	- - -	183.00 €~3,544.00 €	Tue 03 Jun 25
	CP-352664 REF: TM-T200202CAS: 1097883-05-0	- - -	To inquire	Tue 03 Jun 25
	Tyk2-IN-20 REF: TM-T201155CAS: 3058568-08-1	- - -	To inquire	Tue 03 Jun 25
	GDC-9918 REF: TM-T201178CAS: 2570375-06-1	- - -	To inquire	Tue 03 Jun 25
	Cenacitinib REF: TM-T201149CAS: 2641636-52-2	- - -	To inquire	Tue 03 Jun 25
	YLIU-4-105-1 REF: TM-T201176CAS: 2417685-83-5	- - -	To inquire	Tue 03 Jun 25
	MM-589 TFA REF: TM-T12091LCAS: 2097887-21-1	98%	1,841.00 €~5,225.00 €	Tue 03 Jun 25
	ITK inhibitor 2 REF: TM-T11690CAS: 1309784-09-5	- - -	53.00 €~1,121.00 €	Tue 03 Jun 25
	AJI-100 REF: TM-T200052CAS: 844435-10-5	- - -	To inquire	Tue 03 Jun 25
	AJI-214 REF: TM-T200387CAS: 1395886-20-0	- - -	To inquire	Tue 03 Jun 25
	JAK2-IN-7 REF: TM-T35900CAS: 2593402-36-7	98.71%	145.00 €~2,357.00 €	Tue 17 Jun 25

discount label

JAK1-IN-16

JAK1-IN-16 (compound 4l) acts as an inhibitor of JAK1/STAT3 and effectively downregulates the expression of …

Formula:

C₂₀H₁₅ClF₃N₃OS

Color and Shape:

Liquid

Molecular weight:

437.87

Ref: TM-T201648

10mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Tuesday 3 Jun 2025

discount label

JAK2-IN-11

CAS:3057053-17-2

JAK2-IN-11 (Example 6) is a JAK2 kinase inhibitor with potent antitumor activity, exhibiting an IC50 …

Formula:

C₃₁H₃₁F₃N₈O₄

Color and Shape:

Liquid

Molecular weight:

639.64

Ref: TM-T201601

10mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Tuesday 3 Jun 2025

discount label

JAK3-IN-7

CAS:1263774-57-7

JAK3-IN-7 is a potent and selective JAK3 inhibitor (IC50<0.01 μM) for the treatment of …

Formula:

C₁₇H₂₀N₆O

Purity:

98.81%

Color and Shape:

Solid

Molecular weight:

324.38

Ref: TM-T10009

1mg		665.00 €
5mg		1,710.00 €

Estimated delivery in United States, on Tuesday 3 Jun 2025

discount label

AZ-3

CAS:2228908-91-4

AZ-3 is a potent and selective JAK1 inhibitor (IC50: 34 nM).

Formula:

C₂₀H₂₈FN₇

Purity:

98%

Color and Shape:

Solid

Molecular weight:

385.48

Ref: TM-T10424

25mg		2,442.00 €
50mg		3,212.00 €
100mg		4,370.00 €

Estimated delivery in United States, on Tuesday 3 Jun 2025

discount label

JBJ-02-112-05

CAS:2748162-29-8

JBJ-02-112-05 is a potent, mutant-selective, allosteric and orally active inhibitor of EGFR with an IC …

Formula:

C₂₇H₂₀N₄O₂S

Purity:

98%

Color and Shape:

Solid

Molecular weight:

464.54

Ref: TM-T11713

25mg		1,444.00 €
50mg		1,882.00 €
100mg		2,375.00 €

Estimated delivery in United States, on Tuesday 3 Jun 2025

discount label

Londamocitinib

CAS:2241039-81-4

Londamocitinib (JAK1-IN-7) is a selective and potent JAK1 inhibitor with anti-inflammatory activity.

Formula:

C₂₈H₃₁F₂N₇O₄S

Purity:

99.47%

Color and Shape:

Solid

Molecular weight:

599.65

Ref: TM-T11706

1mg		180.00 €
5mg		439.00 €
10mg		597.00 €
25mg		905.00 €
50mg		1,169.00 €
100mg		1,568.00 €
1mL*10mM (DMSO)		567.00 €

Estimated delivery in United States, on Tuesday 3 Jun 2025

discount label

JDTic dihydrochloride

JDTic dihydrochloride

CAS:785835-79-2

JDTic is a powerful antagonist of kappa-opioid receptors (KOR), effectively inhibiting the antinociceptive effects induced …

Formula:

C₂₈H₄₁Cl₂N₃O₃

Purity:

98%

Color and Shape:

Solid

Molecular weight:

538.55

Ref: TM-T11721L

2mg		104.00 €
25mg		635.00 €
50mg		825.00 €
100mg		1,225.00 €

Estimated delivery in United States, on Tuesday 3 Jun 2025

discount label

GDC-0339

CAS:1428569-85-0

GDC-0339: oral Pim kinase inhibitor for multiple myeloma (Kis: Pim1 - 0.03 nM, Pim2 - …

Formula:

C₂₀H₂₂F₃N₇OS

Color and Shape:

Solid

Molecular weight:

465.5

Ref: TM-T15376

25mg		1,568.00 €
50mg		2,043.00 €
100mg		3,544.00 €

Estimated delivery in United States, on Tuesday 3 Jun 2025

discount label

CP-352664

CAS:1097883-05-0

CP-352664 is a JAK inhibitor with potency against JAK3, exhibiting an EC50 value of 210 …

Formula:

C₁₈H₁₈N₄

Color and Shape:

Liquid

Molecular weight:

290.36

Ref: TM-T200202

10mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Tuesday 3 Jun 2025

discount label

Tyk2-IN-20

CAS:3058568-08-1

Tyk2-IN-20 (Example 289) is an effective inhibitor of Tyk2 with an IC50 value below 5 …

Formula:

C₂₄H₂₅N₇O₂

Color and Shape:

Liquid

Molecular weight:

443.50

Ref: TM-T201155

10mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Tuesday 3 Jun 2025

discount label

GDC-9918

CAS:2570375-06-1

GDC-9918 (compound GDC-9918) is an inhibitor of Janus kinases.

Formula:

C₂₀H₁₈F₂N₆O₅S

Color and Shape:

Liquid

Molecular weight:

492.46

Ref: TM-T201178

10mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Tuesday 3 Jun 2025

discount label

Cenacitinib

CAS:2641636-52-2

Cenacitinib is an effective inhibitor of Janus kinase (Janus kinase) and possesses anti-inflammatory activity.

Formula:

C₁₉H₁₉F₂N₇O₃

Color and Shape:

Liquid

Molecular weight:

431.40

Ref: TM-T201149

10mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Tuesday 3 Jun 2025

discount label

YLIU-4-105-1

CAS:2417685-83-5

YLIU-4-105-1 is a type II JAK2 inhibitor. Demonstrating in vivo pharmacological activity, YLIU-4-105-1 reduces splenic …

Formula:

C₃₂H₃₄F₃N₇O₂

Color and Shape:

Liquid

Molecular weight:

605.65

Ref: TM-T201176

10mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Tuesday 3 Jun 2025

discount label

MM-589 TFA

CAS:2097887-21-1

MM-589 TFA is a potent WD repeat domain 5 (WDR5)inhibitor and mixed lineage leukemia (MLL) …

Formula:

C₃₀H₄₅F₃N₈O₇

Purity:

98%

Color and Shape:

Solid

Molecular weight:

686.72

Ref: TM-T12091L

25mg		2,870.00 €
50mg		3,781.00 €
100mg		5,225.00 €

Estimated delivery in United States, on Tuesday 3 Jun 2025

discount label

ITK inhibitor 2

ITK inhibitor 2

CAS:1309784-09-5

ITK inhibitor 2 is a interleukin-2-inducible T-cell kinase (ITK) inhibitor , with an IC50 of …

Formula:

C₂₅H₃₃N₅O₂

Color and Shape:

Solid

Molecular weight:

435.56

Ref: TM-T11690

50mg		748.00 €
100mg		1,121.00 €

Estimated delivery in United States, on Tuesday 3 Jun 2025

discount label

AJI-100

CAS:844435-10-5

AJI-100 serves as a dual-target inhibitor, effectively blocking Aurora kinase A and JAK2, with respective …

Formula:

C₁₇H₁₄FN₅O

Color and Shape:

Liquid

Molecular weight:

323.32

Ref: TM-T200052

10mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Tuesday 3 Jun 2025

discount label

AJI-214

CAS:1395886-20-0

AJI-214 functions as a dual-target inhibitor that specifically blocks Aurora kinase A and JAK2. By …

Formula:

C₁₇H₁₃ClFN₅O

Color and Shape:

Liquid

Molecular weight:

357.77

Ref: TM-T200387

10mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Tuesday 3 Jun 2025

discount label

JAK2-IN-7

CAS:2593402-36-7

JAK2-IN-7 selectively inhibits JAK2 (IC50: 3 nM), shows 14-fold selectivity over JAK1/3, FLT3, induces G0/G1 …

Formula:

C₂₆H₃₃N₇O

Purity:

98.71%

Color and Shape:

Solid

Molecular weight:

459.59

Ref: TM-T35900

1mg		145.00 €
5mg		354.00 €
10mg		630.00 €
25mg		1,301.00 €
50mg		1,738.00 €
100mg		2,357.00 €
1mL*10mM (DMSO)		358.00 €

Estimated delivery in United States, on Tuesday 17 Jun 2025

Welcome to CymitQuimica!

We use cookies to enhance your visit. We do not include advertising.

Please see our Cookies Policy for more details or adjust your preferences in "Settings".

SettingsHide settings