JAK/STAT signaling
JAK/STAT signaling inhibitors are compounds that disrupt the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway, which is involved in cytokine signaling, cell growth, and immune response. These inhibitors are important tools in studying the regulation of this pathway and its role in various diseases, including cancers, immune disorders, and inflammatory conditions. JAK/STAT inhibitors are also being developed as targeted therapies for these diseases. At CymitQuimica, we provide a wide selection of high-quality JAK/STAT signaling inhibitors to support your research in molecular biology, oncology, and immunology.
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Products of "JAK/STAT signaling"
JAK1-IN-10
CAS:2416858-88-1
JAK1-IN-10 (compound 9), a cyano-substituted cyclic hydrazine derivative, functions as a potent and selective inhibitor …
Formula:
C15H17N7
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
295.34
Ref: TM-T79078
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 6 May 2025
STAT3-IN-18
CAS:2668267-41-0
STAT3-IN-18 (compound SPP), a platinum (IV) complex featuring an axial ligand from sandalwood, suppresses the …
Formula:
C18H24Cl2N2O6Pt
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
630.38
Ref: TM-T79609
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 6 May 2025
GNE-955
CAS:1527523-39-2
GNE-955 is a potent and orally active inhibitor of pan Pim kinase (Kis: 0.018, 0.11, …
Formula:
C22H24N8O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
416.48
Ref: TM-T15406
| 25mg | 1,872.00 € | ||
| 50mg | 2,452.00 € | ||
| 100mg | 3,230.00 € |
Estimated delivery in United States, on Tuesday 6 May 2025
ABBV-712
CAS:2368945-27-9
ABBV-712 is a selective Tyrosine Kinase 2 (TYK2) inhibitor, demonstrating an IC50 value of 0.195 …
Formula:
C24H28N4O5
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
452.5
Ref: TM-T83218
| 5mg | 1,415.00 € | ||
| 10mg | 1,908.00 € | ||
| 25mg | 2,547.00 € | ||
| 50mg | 3,212.00 € |
Estimated delivery in United States, on Tuesday 6 May 2025
JAK1-IN-11
CAS:2427608-43-1
JAK1-IN-11 (compound 11) serves as a potent inhibitor of Janus kinases, exhibiting nanomolar inhibitory concentrations …
Formula:
C26H36N6O4S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
528.67
Ref: TM-T79079
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 6 May 2025
JAK-IN-26
CAS:2417134-93-9
JAK-IN-26 (compound 2) is an orally active inhibitor of the Janus kinase (JAK) enzyme with …
Formula:
C22H24N6O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
420.46
Ref: TM-T78189
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 6 May 2025
HS94
CAS:1892594-93-2
HS94 (DAPK3 inhibitor HS94) is a selective and potent DAPK3 inhibitor with a Ki value …
Formula:
C15H15N5O2S
Purity:
95.04%
Color and Shape:
Liquid
Molecular weight:
329.38
Ref: TM-T77777
| 1mg | 40.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 117.00 € | ||
| 25mg | 227.00 € | ||
| 50mg | 338.00 € | ||
| 100mg | 500.00 € | ||
| 500mg | 1,074.00 € |
Estimated delivery in United States, on Tuesday 6 May 2025
Ginsenoside Rk1
CAS:494753-69-4
Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures.
Formula:
C42H70O12
Purity:
99.13%
Color and Shape:
Solid
Molecular weight:
767
Ref: TM-T4S1499
| 5mg | 93.00 € |
Estimated delivery in United States, on Tuesday 6 May 2025
JAK-IN-31
CAS:2597016-88-9
JAK-IN-31 (Example 75), a JAK inhibitor, demonstrates IC50 values of ≤0.01 µM for JAK1, ≤0.01 …
Formula:
C21H19N7O2S2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
465.55
Ref: TM-T79882
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 6 May 2025
JAK-IN-27
CAS:2673176-36-6
JAK-IN-27, also known as compound 1, is an orally active, potent inhibitor of the JAKS …
Formula:
C20H21F2N7O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
413.42
Ref: TM-T79110
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 6 May 2025
DPP
CAS:2668267-47-6
DPP, a Platinum(IV) complex with a pterostilbene-derived axial ligand, inhibits the JAK2-STAT3 pathway in breast …
Formula:
C36H40Cl2N2O10Pt
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
926.7
Ref: TM-T79608
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 6 May 2025
QL-1200186
CAS:2848664-42-4
QL-1200186 is an orally active, selective TYK2 inhibitor that, upon dose-dependent oral administration, suppresses interferon-γ …
Formula:
C26H27N7O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
485.54
Ref: TM-T81331
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 6 May 2025
JAK kinase-IN-1
CAS:2698389-43-2
JAK kinase-IN-1 (Example 1) functions as a potent inhibitor targeting the JAK family, which includes …
Formula:
C17H19F2N7OS
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
407.44
Ref: TM-T79807
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 6 May 2025
JAK-IN-25
CAS:2127110-22-7
JAK-IN-25 (compound 19), a potent JAK inhibitor, exhibits IC50 values of 6 nM for TYK2, …
Formula:
C19H17N5O4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
379.37
Ref: TM-T78175
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 6 May 2025
JAK-IN-5
CAS:2096999-92-5
JAK-IN-5 is a JAK inhibitor.
Formula:
C27H31FN6O
Purity:
97.78% - 98.78%
Color and Shape:
Solid
Molecular weight:
474.57
Ref: TM-T11710
| 1mg | 187.00 € | ||
| 5mg | 391.00 € | ||
| 10mg | 582.00 € | ||
| 25mg | 929.00 € | ||
| 50mg | 1,254.00 € | ||
| 100mg | 1,691.00 € | ||
| 500mg | 3,382.00 € | ||
| 1mL*10mM (DMSO) | 567.00 € |
Estimated delivery in United States, on Tuesday 6 May 2025
PIM1-IN-4
CAS:2762767-48-4
PIM1-IN-4: strong PIM1 inhibitor, also blocks SGK-1, PKA, CaMK-1, GSK3β, MSK1; promising for cancer studies.
Formula:
C27H25BrCl2CuN6O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
663.88
Ref: TM-T73247
| 25mg | 1,586.00 € | ||
| 50mg | 2,072.00 € | ||
| 100mg | 2,660.00 € |
Estimated delivery in United States, on Tuesday 6 May 2025
PIM-IN-2
CAS:1006699-45-1
PIM-IN-2 (Pim-2) is a potent inhibitor of Pim kinases, demonstrating an inhibition concentration half-maximal (IC50) …
Formula:
C19H22N4O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
338.4
Ref: TM-T81460
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 6 May 2025
JAK3 covalent inhibitor-1
CAS:2300106-50-5
JAK3 Covalent Inhibitor-1 is a compound characterized by its potent and selective inhibition of Janus …
Formula:
C22H17FN6O2S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
448.47
Ref: TM-T11709
| 25mg | 2,585.00 € | ||
| 50mg | 3,402.00 € | ||
| 100mg | 4,655.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
MM-589
CAS:2097887-20-0
MM-589 is a potent WD repeat domain 5 (WDR5) inhibitor and mixed lineage leukemia (MLL) …
Formula:
C28H44N8O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
572.70
Ref: TM-T12091
| 25mg | 2,870.00 € | ||
| 50mg | 3,781.00 € | ||
| 100mg | 5,225.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
(R)-9b
CAS:1655527-68-6
(R)-9b is an effective inhibitor of the ACK1 tyrosine kinase (IC50=56 nM) and exhibits anticancer …
Formula:
C20H27ClN6O
Color and Shape:
Liquid
Molecular weight:
402.92
Ref: TM-T201776
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Jun 2025
