JAK/STAT signaling
JAK/STAT signaling inhibitors are compounds that disrupt the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway, which is involved in cytokine signaling, cell growth, and immune response. These inhibitors are important tools in studying the regulation of this pathway and its role in various diseases, including cancers, immune disorders, and inflammatory conditions. JAK/STAT inhibitors are also being developed as targeted therapies for these diseases. At CymitQuimica, we provide a wide selection of high-quality JAK/STAT signaling inhibitors to support your research in molecular biology, oncology, and immunology.
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Products of "JAK/STAT signaling"
DPP
CAS:2668267-47-6
DPP, a Platinum(IV) complex with a pterostilbene-derived axial ligand, inhibits the JAK2-STAT3 pathway in breast …
Formula:
C36H40Cl2N2O10Pt
Purity:
98%
Color and Shape:
Solid
Molecular weight:
926.7
Ref: TM-T79608
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 2 Jan 2025
QL-1200186
CAS:2848664-42-4
QL-1200186 is an orally active, selective TYK2 inhibitor that, upon dose-dependent oral administration, suppresses interferon-γ …
Formula:
C26H27N7O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
485.54
Ref: TM-T81331
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 2 Jan 2025
JAK kinase-IN-1
CAS:2698389-43-2
JAK kinase-IN-1 (Example 1) functions as a potent inhibitor targeting the JAK family, which includes …
Formula:
C17H19F2N7OS
Purity:
98%
Color and Shape:
Solid
Molecular weight:
407.44
Ref: TM-T79807
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 2 Jan 2025
JAK-IN-25
CAS:2127110-22-7
JAK-IN-25 (compound 19), a potent JAK inhibitor, exhibits IC50 values of 6 nM for TYK2, …
Formula:
C19H17N5O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
379.37
Ref: TM-T78175
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 2 Jan 2025
PIM-IN-2
CAS:1006699-45-1
PIM-IN-2 (Pim-2) is a potent inhibitor of Pim kinases, demonstrating an inhibition concentration half-maximal (IC50) …
Formula:
C19H22N4O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
338.4
Ref: TM-T81460
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 2 Jan 2025
JAK-IN-5
CAS:2096999-92-5
JAK-IN-5 is a JAK inhibitor.
Formula:
C27H31FN6O
Purity:
97.78% - 98.78%
Color and Shape:
Solid
Molecular weight:
474.57
Ref: TM-T11710
| 1mg | 183.00 € | ||
| 5mg | 385.00 € | ||
| 10mg | 570.00 € | ||
| 25mg | 907.00 € | ||
| 50mg | 1,230.00 € | ||
| 100mg | 1,660.00 € | ||
| 500mg | 3,316.00 € | ||
| 1mL*10mM (DMSO) | 564.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
Brepocitinib
CAS:1883299-62-4
Brepocitinib (PF-06700841) is a potent dual JAK1/TYK2 inhibitor (IC50s: 17 nM/23 nM). Brepocitinib also inhibits …
Formula:
C18H21F2N7O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
389.4
Ref: TM-TQ0010
| 1mg | 35.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 102.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 383.00 € | ||
| 100mg | 614.00 € | ||
| 200mg | 859.00 € | ||
| 500mg | 1,270.00 € | ||
| 1mL*10mM (DMSO) | 117.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
PIM1-IN-4
CAS:2762767-48-4
PIM1-IN-4: strong PIM1 inhibitor, also blocks SGK-1, PKA, CaMK-1, GSK3β, MSK1; promising for cancer studies.
Formula:
C27H25BrCl2CuN6O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
663.88
Ref: TM-T73247
| 25mg | 1,549.00 € | ||
| 50mg | 2,038.00 € | ||
| 100mg | 2,617.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
JAK1-IN-11
CAS:2427608-43-1
JAK1-IN-11 (compound 11) serves as a potent inhibitor of Janus kinases, exhibiting nanomolar inhibitory concentrations …
Formula:
C26H36N6O4S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
528.67
Ref: TM-T79079
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 2 Jan 2025
HS94
CAS:1892594-93-2
HS94 (DAPK3 inhibitor HS94) is a selective and potent DAPK3 inhibitor with a Ki value …
Formula:
C15H15N5O2S
Purity:
95.04%
Color and Shape:
Solid
Molecular weight:
329.38
Ref: TM-T77777
| 1mg | 40.00 € | ||
| 5mg | 85.00 € | ||
| 10mg | 116.00 € | ||
| 25mg | 224.00 € | ||
| 50mg | 333.00 € | ||
| 100mg | 494.00 € | ||
| 500mg | 1,058.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
JAK3 covalent inhibitor-1
CAS:2300106-50-5
JAK3 Covalent Inhibitor-1 is a compound characterized by its potent and selective inhibition of Janus …
Formula:
C22H17FN6O2S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
448.47
Ref: TM-T11709
| 25mg | 2,523.00 € | ||
| 50mg | 3,346.00 € | ||
| 100mg | 4,580.00 € |
Estimated delivery in United States, on Thursday 30 Jan 2025
AZ-3
CAS:2228908-91-4
AZ-3 is a potent and selective JAK1 inhibitor (IC50: 34 nM).
Formula:
C20H28FN7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
385.48
Ref: TM-T10424
| 25mg | 2,384.00 € | ||
| 50mg | 3,159.00 € | ||
| 100mg | 4,299.00 € |
Estimated delivery in United States, on Thursday 30 Jan 2025
Londamocitinib
CAS:2241039-81-4
Londamocitinib (JAK1-IN-7) is a selective and potent JAK1 inhibitor with anti-inflammatory activity.
Formula:
C28H31F2N7O4S
Purity:
99.47%
Color and Shape:
Solid
Molecular weight:
599.65
Ref: TM-T11706
| 1mg | 176.00 € | ||
| 5mg | 430.00 € | ||
| 10mg | 584.00 € | ||
| 25mg | 884.00 € | ||
| 50mg | 1,141.00 € | ||
| 100mg | 1,531.00 € | ||
| 1mL*10mM (DMSO) | 554.00 € |
Estimated delivery in United States, on Thursday 30 Jan 2025
ITK inhibitor 2
CAS:1309784-09-5
ITK inhibitor 2 is a interleukin-2-inducible T-cell kinase (ITK) inhibitor , with an IC50 of …
Formula:
C25H33N5O2
Color and Shape:
Solid
Molecular weight:
435.56
Ref: TM-T11690
| 50mg | 738.00 € | ||
| 100mg | 1,105.00 € |
Estimated delivery in United States, on Thursday 30 Jan 2025
JBJ-02-112-05
CAS:2748162-29-8
JBJ-02-112-05 is a potent, mutant-selective, allosteric and orally active inhibitor of EGFR with an IC …
Formula:
C27H20N4O2S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
464.54
Ref: TM-T11713
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Thursday 30 Jan 2025
GDC-0339
CAS:1428569-85-0
GDC-0339: oral Pim kinase inhibitor for multiple myeloma (Kis: Pim1 - 0.03 nM, Pim2 - …
Formula:
C20H22F3N7OS
Color and Shape:
Solid
Molecular weight:
465.5
Ref: TM-T15376
| 25mg | 1,531.00 € | ||
| 50mg | 2,013.00 € | ||
| 100mg | 3,491.00 € |
Estimated delivery in United States, on Thursday 30 Jan 2025
MM-589
CAS:2097887-20-0
MM-589 is a potent WD repeat domain 5 (WDR5) inhibitor and mixed lineage leukemia (MLL) …
Formula:
C28H44N8O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
572.7
Ref: TM-T12091
| 25mg | 2,801.00 € | ||
| 50mg | 3,722.00 € | ||
| 100mg | 5,144.00 € |
Estimated delivery in United States, on Thursday 30 Jan 2025
JDTic dihydrochloride
CAS:785835-79-2
JDTic is a powerful antagonist of kappa-opioid receptors (KOR), effectively inhibiting the antinociceptive effects induced …
Formula:
C28H41Cl2N3O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
538.55
Ref: TM-T11721L
| 2mg | 102.00 € | ||
| 25mg | 620.00 € | ||
| 50mg | 813.00 € | ||
| 100mg | 1,208.00 € |
Estimated delivery in United States, on Thursday 30 Jan 2025
JAK3-IN-7
CAS:1263774-57-7
JAK3-IN-7 is a potent and selective JAK3 inhibitor (IC50<0.01 μM) for the treatment of …
Formula:
C17H20N6O
Purity:
98.81%
Color and Shape:
Solid
Molecular weight:
324.38
Ref: TM-T10009
| 1mg | 650.00 € | ||
| 5mg | 1,678.00 € |
Estimated delivery in United States, on Thursday 30 Jan 2025
MM-589 TFA
CAS:2097887-21-1
MM-589 TFA is a potent WD repeat domain 5 (WDR5)inhibitor and mixed lineage leukemia (MLL) …
Formula:
C30H45F3N8O7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
686.72
Ref: TM-T12091L
| 25mg | 2,801.00 € | ||
| 50mg | 3,720.00 € | ||
| 100mg | 5,140.00 € |
Estimated delivery in United States, on Thursday 30 Jan 2025
