JAK/STAT signaling
JAK/STAT signaling inhibitors are compounds that disrupt the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway, which is involved in cytokine signaling, cell growth, and immune response. These inhibitors are important tools in studying the regulation of this pathway and its role in various diseases, including cancers, immune disorders, and inflammatory conditions. JAK/STAT inhibitors are also being developed as targeted therapies for these diseases. At CymitQuimica, we provide a wide selection of high-quality JAK/STAT signaling inhibitors to support your research in molecular biology, oncology, and immunology.
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Products of "JAK/STAT signaling"
AJI-214
CAS:1395886-20-0
AJI-214 functions as a dual-target inhibitor that specifically blocks Aurora kinase A and JAK2. By …
Formula:
C17H13ClFN5O
Color and Shape:
Liquid
Molecular weight:
357.77
Ref: TM-T200387
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 3 Mar 2025
JAK3 covalent inhibitor-1
CAS:2300106-50-5
JAK3 Covalent Inhibitor-1 is a compound characterized by its potent and selective inhibition of Janus …
Formula:
C22H17FN6O2S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
448.47
Ref: TM-T11709
| 25mg | 2,523.00 € | ||
| 50mg | 3,346.00 € | ||
| 100mg | 4,580.00 € |
Estimated delivery in United States, on Monday 3 Mar 2025
AZ-3
CAS:2228908-91-4
AZ-3 is a potent and selective JAK1 inhibitor (IC50: 34 nM).
Formula:
C20H28FN7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
385.48
Ref: TM-T10424
| 25mg | 2,384.00 € | ||
| 50mg | 3,159.00 € | ||
| 100mg | 4,299.00 € |
Estimated delivery in United States, on Monday 3 Mar 2025
JAK3-IN-7
CAS:1263774-57-7
JAK3-IN-7 is a potent and selective JAK3 inhibitor (IC50<0.01 μM) for the treatment of …
Formula:
C17H20N6O
Purity:
98.81%
Color and Shape:
Solid
Molecular weight:
324.38
Ref: TM-T10009
| 1mg | 650.00 € | ||
| 5mg | 1,678.00 € |
Estimated delivery in United States, on Monday 3 Mar 2025
ITK inhibitor 2
CAS:1309784-09-5
ITK inhibitor 2 is a interleukin-2-inducible T-cell kinase (ITK) inhibitor , with an IC50 of …
Formula:
C25H33N5O2
Color and Shape:
Solid
Molecular weight:
435.56
Ref: TM-T11690
| 50mg | 738.00 € | ||
| 100mg | 1,105.00 € |
Estimated delivery in United States, on Monday 3 Mar 2025
MM-589 TFA
CAS:2097887-21-1
MM-589 TFA is a potent WD repeat domain 5 (WDR5)inhibitor and mixed lineage leukemia (MLL) …
Formula:
C30H45F3N8O7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
686.72
Ref: TM-T12091L
| 25mg | 2,801.00 € | ||
| 50mg | 3,720.00 € | ||
| 100mg | 5,140.00 € |
Estimated delivery in United States, on Monday 3 Mar 2025
JAK2-IN-7
CAS:2593402-36-7
JAK2-IN-7 selectively inhibits JAK2 (IC50: 3 nM), shows 14-fold selectivity over JAK1/3, FLT3, induces G0/G1 …
Formula:
C26H33N7O
Purity:
98.71%
Color and Shape:
Solid
Molecular weight:
459.59
Ref: TM-T35900
| 1mg | 147.00 € | ||
| 5mg | 357.00 € | ||
| 10mg | 636.00 € | ||
| 25mg | 1,314.00 € | ||
| 50mg | 1,755.00 € | ||
| 100mg | 2,379.00 € | ||
| 200mg | 1,811.00 € | ||
| 1mL*10mM (DMSO) | 361.00 € |
Estimated delivery in United States, on Monday 17 Mar 2025
Tofacitinib
CAS:477600-75-2
Tofacitinib (Tasocitinib) is an orally Janus kinase inhibitor. Tofacitinib is used for the treatment of …
Formula:
C16H20N6O
Purity:
100%
Color and Shape:
Solid
Molecular weight:
312.37
Ref: TM-T6321
| 1ml | Discontinued | Request information | |
| 5mg | Discontinued | Request information | |
| 10mg | Discontinued | Request information | |
| 25mg | Discontinued | Request information | |
| 50mg | Discontinued | Request information | |
| 100mg | Discontinued | Request information | |
| 200mg | Discontinued | Request information | |
| 500mg | Discontinued | Request information | |
| 1ml*10 (DMSO) | Discontinued | Request information |
