JAK/STAT signaling
JAK/STAT signaling inhibitors are compounds that disrupt the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway, which is involved in cytokine signaling, cell growth, and immune response. These inhibitors are important tools in studying the regulation of this pathway and its role in various diseases, including cancers, immune disorders, and inflammatory conditions. JAK/STAT inhibitors are also being developed as targeted therapies for these diseases. At CymitQuimica, we provide a wide selection of high-quality JAK/STAT signaling inhibitors to support your research in molecular biology, oncology, and immunology.
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Products of "JAK/STAT signaling"
AZ-3
CAS:2228908-91-4
AZ-3 is a potent and selective JAK1 inhibitor (IC50: 34 nM).
Formula:
C20H28FN7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
385.48
Ref: TM-T10424
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Wednesday 30 Jul 2025
JAK3 covalent inhibitor-1
CAS:2300106-50-5
JAK3 Covalent Inhibitor-1 is a compound characterized by its potent and selective inhibition of Janus …
Formula:
C22H17FN6O2S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
448.47
Ref: TM-T11709
| 25mg | 3,515.00 € | ||
| 50mg | 4,694.00 € | ||
| 100mg | 5,853.00 € |
Estimated delivery in United States, on Wednesday 30 Jul 2025
YLIU-4-105-1
CAS:2417685-83-5
YLIU-4-105-1 is a type II JAK2 inhibitor. Demonstrating in vivo pharmacological activity, YLIU-4-105-1 reduces splenic …
Formula:
C32H34F3N7O2
Color and Shape:
Solid
Molecular weight:
605.65
Ref: TM-T201176
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 30 Jul 2025
AJI-214
CAS:1395886-20-0
AJI-214 functions as a dual-target inhibitor that specifically blocks Aurora kinase A and JAK2. By …
Formula:
C17H13ClFN5O
Color and Shape:
Solid
Molecular weight:
357.77
Ref: TM-T200387
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 30 Jul 2025
Cenacitinib
CAS:2641636-52-2
Cenacitinib is an effective inhibitor of Janus kinase (Janus kinase) and possesses anti-inflammatory activity.
Formula:
C19H19F2N7O3
Color and Shape:
Solid
Molecular weight:
431.40
Ref: TM-T201149
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 30 Jul 2025
GDC-9918
CAS:2570375-06-1
GDC-9918 (compound GDC-9918) is an inhibitor of Janus kinases.
Formula:
C20H18F2N6O5S
Color and Shape:
Solid
Molecular weight:
492.46
Ref: TM-T201178
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 30 Jul 2025
Tyk2-IN-20
CAS:3058568-08-1
Tyk2-IN-20 (Example 289) is an effective inhibitor of Tyk2 with an IC50 value below 5 …
Formula:
C24H25N7O2
Color and Shape:
Solid
Molecular weight:
443.50
Ref: TM-T201155
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 30 Jul 2025
JDTic dihydrochloride
CAS:785835-79-2
JDTic is a powerful antagonist of kappa-opioid receptors (KOR), effectively inhibiting the antinociceptive effects induced …
Formula:
C28H41Cl2N3O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
538.55
Ref: TM-T11721L
| 2mg | 104.00 € | ||
| 25mg | 635.00 € | ||
| 50mg | 825.00 € | ||
| 100mg | 1,225.00 € |
Estimated delivery in United States, on Wednesday 30 Jul 2025
GDC-0339
CAS:1428569-85-0
GDC-0339: oral Pim kinase inhibitor for multiple myeloma (Kis: Pim1 - 0.03 nM, Pim2 - …
Formula:
C20H22F3N7OS
Color and Shape:
Solid
Molecular weight:
465.5
Ref: TM-T15376
| 25mg | 1,568.00 € | ||
| 50mg | 2,043.00 € | ||
| 100mg | 3,544.00 € |
Estimated delivery in United States, on Wednesday 30 Jul 2025
Londamocitinib
CAS:2241039-81-4
Londamocitinib (JAK1-IN-7) is a selective and potent JAK1 inhibitor with anti-inflammatory activity.
Formula:
C28H31F2N7O4S
Purity:
99.47%
Color and Shape:
Solid
Molecular weight:
599.65
Ref: TM-T11706
| 1mg | 180.00 € | ||
| 5mg | 439.00 € | ||
| 10mg | 597.00 € | ||
| 25mg | 905.00 € | ||
| 50mg | 1,169.00 € | ||
| 100mg | 1,568.00 € | ||
| 1mL*10mM (DMSO) | 567.00 € |
Estimated delivery in United States, on Wednesday 30 Jul 2025
JBJ-02-112-05
CAS:2748162-29-8
JBJ-02-112-05 is a potent, mutant-selective, allosteric and orally active inhibitor of EGFR with an IC …
Formula:
C27H20N4O2S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
464.54
Ref: TM-T11713
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Wednesday 30 Jul 2025
ITK inhibitor 2
CAS:1309784-09-5
ITK inhibitor 2 is a interleukin-2-inducible T-cell kinase (ITK) inhibitor , with an IC50 of …
Formula:
C25H33N5O2
Color and Shape:
Solid
Molecular weight:
435.56
Ref: TM-T11690
| 50mg | 748.00 € | ||
| 100mg | 1,121.00 € |
Estimated delivery in United States, on Wednesday 30 Jul 2025
MM-589 TFA
CAS:2097887-21-1
MM-589 TFA is a potent WD repeat domain 5 (WDR5)inhibitor and mixed lineage leukemia (MLL) …
Formula:
C30H45F3N8O7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
686.72
Ref: TM-T12091L
| 25mg | 2,727.00 € | ||
| 50mg | 3,591.00 € | ||
| 100mg | 4,940.00 € |
Estimated delivery in United States, on Wednesday 30 Jul 2025
MM-589
CAS:2097887-20-0
MM-589 is a potent WD repeat domain 5 (WDR5) inhibitor and mixed lineage leukemia (MLL) …
Formula:
C28H44N8O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
572.70
Ref: TM-T12091
| 25mg | 2,727.00 € | ||
| 50mg | 3,591.00 € | ||
| 100mg | 4,940.00 € |
Estimated delivery in United States, on Wednesday 30 Jul 2025
CP-352664
CAS:1097883-05-0
CP-352664 is a JAK inhibitor with potency against JAK3, exhibiting an EC50 value of 210 …
Formula:
C18H18N4
Color and Shape:
Solid
Molecular weight:
290.36
Ref: TM-T200202
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Wednesday 30 Jul 2025
AJI-100
CAS:844435-10-5
AJI-100 serves as a dual-target inhibitor, effectively blocking Aurora kinase A and JAK2, with respective …
Formula:
C17H14FN5O
Color and Shape:
Solid
Molecular weight:
323.32
Ref: TM-T200052
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Wednesday 30 Jul 2025
(R)-9b
CAS:1655527-68-6
(R)-9b is an effective inhibitor of the ACK1 tyrosine kinase (IC50=56 nM) and exhibits anticancer …
Formula:
C20H27ClN6O
Color and Shape:
Liquid
Molecular weight:
402.92
Ref: TM-T201776
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 30 Jul 2025
JAK1-IN-16
JAK1-IN-16 (compound 4l) acts as an inhibitor of JAK1/STAT3 and effectively downregulates the expression of …
Formula:
C20H15ClF3N3OS
Color and Shape:
Liquid
Molecular weight:
437.87
Ref: TM-T201648
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 30 Jul 2025
JAK2-IN-11
CAS:3057053-17-2
JAK2-IN-11 (Example 6) is a JAK2 kinase inhibitor with potent antitumor activity, exhibiting an IC50 …
Formula:
C31H31F3N8O4
Color and Shape:
Liquid
Molecular weight:
639.64
Ref: TM-T201601
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 30 Jul 2025
JAK2-IN-7
CAS:2593402-36-7
JAK2-IN-7 selectively inhibits JAK2 (IC50: 3 nM), shows 14-fold selectivity over JAK1/3, FLT3, induces G0/G1 …
Formula:
C26H33N7O
Purity:
98.71%
Color and Shape:
Solid
Molecular weight:
459.59
Ref: TM-T35900
| 1mg | 145.00 € | ||
| 5mg | 354.00 € | ||
| 10mg | 630.00 € | ||
| 25mg | 1,301.00 € | ||
| 50mg | 1,738.00 € | ||
| 100mg | 2,357.00 € | ||
| 1mL*10mM (DMSO) | 358.00 € |
Estimated delivery in United States, on Wednesday 13 Aug 2025
