JAK/STAT signaling
JAK/STAT signaling inhibitors are compounds that disrupt the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway, which is involved in cytokine signaling, cell growth, and immune response. These inhibitors are important tools in studying the regulation of this pathway and its role in various diseases, including cancers, immune disorders, and inflammatory conditions. JAK/STAT inhibitors are also being developed as targeted therapies for these diseases. At CymitQuimica, we provide a wide selection of high-quality JAK/STAT signaling inhibitors to support your research in molecular biology, oncology, and immunology.
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Products of "JAK/STAT signaling"
Uzansertib phosphate
CAS:2088852-47-3
Uzansertib phosphate (INCB053914 phosphate) is an orally active, ATP-competitive inhibitor of pan-PIM kinase, inhibiting PIM1, …
Formula:
C26H29F3N5O7P
Purity:
99.75% - 99.85%
Color and Shape:
Solid
Molecular weight:
611.51
Ref: TM-T12477
| 1mg | 87.00 € | ||
| 5mg | 216.00 € | ||
| 10mg | 329.00 € | ||
| 25mg | 593.00 € | ||
| 50mg | 832.00 € | ||
| 100mg | 1,159.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
Ilginatinib
CAS:1239358-86-1
Ilginatinib (NS-018) is a highly active and orally bioavailable inhibitor of JAK2.
Formula:
C21H20FN7
Purity:
98.40% - 99.01%
Color and Shape:
Solid
Molecular weight:
389.43
Ref: TM-T12266
| 1mg | 64.00 € | ||
| 5mg | 138.00 € | ||
| 10mg | 187.00 € | ||
| 25mg | 273.00 € | ||
| 50mg | 393.00 € | ||
| 100mg | 562.00 € | ||
| 200mg | 743.00 € | ||
| 1mL*10mM (DMSO) | 133.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
Ilginatinib maleate
CAS:1354799-87-3
Ilginatinib maleate (NS-018 maleate) is a highly active and orally bioavailable inhibitor of JAK2.
Formula:
C25H24FN7O4
Purity:
99.74% - 99.82%
Color and Shape:
Solid
Molecular weight:
505.5
Ref: TM-T12266L
| 1mg | 64.00 € | ||
| 5mg | 138.00 € | ||
| 10mg | 187.00 € | ||
| 25mg | 273.00 € | ||
| 50mg | 393.00 € | ||
| 100mg | 562.00 € | ||
| 200mg | 743.00 € | ||
| 1mL*10mM (DMSO) | 153.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
Gusacitinib
CAS:1425381-60-7
Gusacitinib (ASN-002) (ASN-002) is spleen tyrosine kinase (SYK) and janus kinase (JAK) inhibitor (IC50: 5-46 …
Formula:
C24H28N8O2
Purity:
99.94%
Color and Shape:
Solid
Molecular weight:
460.53
Ref: TM-T14331
| 1mg | 42.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 188.00 € | ||
| 50mg | 350.00 € | ||
| 100mg | 522.00 € | ||
| 200mg | 750.00 € | ||
| 1mL*10mM (DMSO) | 116.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
Delgocitinib
CAS:1263774-59-9
Delgocitinib is a potent JAK inhibitor (IC50: 2.8-58 nM), treats inflammatory diseases, and is the …
Formula:
C16H18N6O
Purity:
99.90%
Color and Shape:
Solid
Molecular weight:
310.35
Ref: TM-T15096
| 1mg | 169.00 € | ||
| 5mg | 311.00 € | ||
| 10mg | 487.00 € | ||
| 25mg | 929.00 € | ||
| 50mg | 1,415.00 € | ||
| 100mg | 2,062.00 € | ||
| 200mg | 2,775.00 € | ||
| 1mL*10mM (DMSO) | 349.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
JAK2 Inhibitor V
CAS:195371-52-9
JAK2 Inhibitor V (JAK2 Inhibitor V Z3) is a novel specific inhibitor of Jak2, inhibiting …
Formula:
C23H24N2O
Purity:
96.69% - 99.15%
Color and Shape:
Solid
Molecular weight:
344.45
Ref: TM-T3042
| 2mg | 39.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 157.00 € | ||
| 50mg | 274.00 € | ||
| 100mg | 505.00 € | ||
| 500mg | 1,121.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
Ilginatinib hydrochloride
CAS:1239358-85-0
Ilginatinib hydrochloride (NS-018 hydrochloride) is a highly active and orally bioavailable inhibitor of JAK2.
Formula:
C21H21ClFN7
Purity:
99.55%
Color and Shape:
Solid
Molecular weight:
425.89
Ref: TM-T12266L2
| 1mg | 93.00 € | ||
| 5mg | 221.00 € | ||
| 10mg | 309.00 € | ||
| 25mg | 454.00 € | ||
| 50mg | 653.00 € | ||
| 100mg | 938.00 € | ||
| 500mg | 1,882.00 € | ||
| 1mL*10mM (DMSO) | 208.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
Brepocitinib P-Tosylate
CAS:2140301-96-6
Brepocitinib P-Tosylate (PF-06700841 P-Tosylate) is a potent dual inhibitor of Janus kinase 1 (JAK1) and …
Formula:
C25H29F2N7O4S
Purity:
99.82% - 99.97%
Color and Shape:
Solid
Molecular weight:
561.6
Ref: TM-T12427
| 1mg | 35.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 104.00 € | ||
| 25mg | 216.00 € | ||
| 50mg | 393.00 € | ||
| 100mg | 628.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
Golidocitinib
CAS:2091134-68-6
Golidocitinib (AZD4205) is a selective JAK1 inhibitor (IC50: 73 nM) and weakly inhibits JAK2/JAK3 (IC50: …
Formula:
C25H31N9O2
Purity:
100% - 98.87%
Color and Shape:
Solid
Molecular weight:
489.57
Ref: TM-T10431
| 2mg | 96.00 € | ||
| 5mg | 163.00 € | ||
| 10mg | 268.00 € | ||
| 25mg | 465.00 € | ||
| 50mg | 618.00 € | ||
| 100mg | 880.00 € | ||
| 1mL*10mM (DMSO) | 170.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
JAK3-IN-15
JAK3-IN-15 (compound 22) is a JAK3 inhibitor that reduces the secretion of p-JAK3 induced by …
Ref: TM-T200631
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 16 Apr 2025
JI069
CAS:850019-35-1
JI069 (WAY-354189) is a potent STAT3 inhibitor that inhibits gp130 signaling by inducing dissociation between …
Formula:
C15H12Cl2N2O4S
Purity:
98.01%
Color and Shape:
Liquid
Molecular weight:
387.24
Ref: TM-T77672
| 1mg | 185.00 € | ||
| 5mg | 459.00 € | ||
| 10mg | 657.00 € | ||
| 25mg | 1,026.00 € | ||
| 50mg | 1,415.00 € | ||
| 100mg | 1,872.00 € | ||
| 500mg | 3,734.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Pim-1 kinase inhibitor 11
Pim-1 kinase inhibitor 11 (10f) is an inhibitor of PIM-1 with an IC50 value of …
Ref: TM-T200676
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 16 Apr 2025
TAK-901
CAS:934541-31-8
TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid …
Formula:
C28H32N4O3S
Purity:
97.38% - 99.1%
Color and Shape:
Solid
Molecular weight:
504.64
Ref: TM-T2709
| 5mg | 72.00 € | ||
| 25mg | 213.00 € | ||
| 50mg | 371.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
WDR5-IN-6
CAS:326901-92-2
WDR5-IN-6 is a WDR5 inhibitor targeting the WBM locus.WDR5-IN-6 is highly synergistic with OICR-9429, a …
Formula:
C13H8Cl2N2O2S
Purity:
99.69%
Color and Shape:
Soild
Molecular weight:
327.19
Ref: TM-T77495
| 1mg | 46.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 144.00 € | ||
| 25mg | 281.00 € | ||
| 50mg | 454.00 € | ||
| 100mg | 725.00 € | ||
| 500mg | 1,473.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Nimucitinib
CAS:2740557-24-6
Nimucitinib is a Janus kinase (JAK) inhibitor that can be used to treat dry eye …
Formula:
C25H26F2N6O2
Purity:
98.71%
Color and Shape:
Soild
Molecular weight:
480.51
Ref: TM-T67907
| 1mg | 96.00 € | ||
| 2mg | 139.00 € | ||
| 5mg | 227.00 € | ||
| 10mg | 354.00 € | ||
| 25mg | 653.00 € | ||
| 50mg | 938.00 € | ||
| 100mg | 1,454.00 € | ||
| 500mg | 2,822.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Povorcitinib phosphate
CAS:1637677-33-8
Povorcitinib phosphate is a selective JAK1 inhibitor and can be used in studies about the …
Formula:
C23H25F5N7O5P
Purity:
97.71%
Color and Shape:
Liquid
Molecular weight:
605.45
Ref: TM-T39113L
| 1mg | 65.00 € | ||
| 2mg | 95.00 € | ||
| 5mg | 145.00 € | ||
| 10mg | 212.00 € | ||
| 25mg | 359.00 € | ||
| 50mg | 512.00 € | ||
| 100mg | 695.00 € | ||
| 200mg | 937.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
JAK/HDAC-IN-2
JAK/HDAC-IN-2, a potent 2-amino-4-phenylaminopyrimidine dual-target inhibitor, effectively suppresses JAK1/2 and HDAC3/6 at nanomolar concentrations.
Formula:
C28H38N6O5S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
570.7
Ref: TM-T78708
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Pim-1 kinase inhibitor 8
CAS:916038-47-6
Pim-1 kinase inhibitor 8 is a Pim-1 kinase inhibitor with anticancer activity that inhibits cell …
Formula:
C14H17N3O3
Purity:
99.81%
Color and Shape:
Soild
Molecular weight:
275.3
Ref: TM-T83627
| 1mg | 63.00 € | ||
| 5mg | 137.00 € | ||
| 10mg | 210.00 € | ||
| 25mg | 424.00 € | ||
| 50mg | 682.00 € | ||
| 100mg | 1,074.00 € | ||
| 500mg | 2,175.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Pumecitinib
CAS:2401057-12-1
Pumecitinib is a Janus kinase (JAK) inhibitor. Pumecitinib exhibits anti-inflammatory activity.
Formula:
C17H20N8O2S
Purity:
99.89%
Color and Shape:
Soild
Molecular weight:
400.46
Ref: TM-T67758
| 5mg | 52.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 128.00 € | ||
| 50mg | 197.00 € | ||
| 100mg | 281.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
JAK-IN-29
JAK-IN-29 (Compound 3) is a potent inhibitor of Janus kinases (JAK) [1].
Formula:
C17H14ClN5O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
355.78
Ref: TM-T79222
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 16 Apr 2025
