STAT
STAT proteins are critical components of the JAK/STAT signaling pathway, which transmits extracellular signals from cytokines and growth factors to the cell nucleus, influencing gene expression. STAT proteins are involved in regulating immune responses, cell growth, differentiation, and survival. Dysregulation of STAT signaling is implicated in various diseases, including cancer, autoimmune disorders, and chronic inflammation. At CymitQuimica, we provide a comprehensive range of STAT pathway modulators to support your research in signal transduction, immunology, and therapeutic development.
Found 98 products of "STAT"
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Atranorin
CAS:<p>Atranorin has antinociceptive, anti-inflammatory, can be pro-oxidant or antioxidant, and protects cells from H(2)O(2)-induced oxidative stress.</p>Formula:C19H18O8Purity:98.76% - 99.57%Color and Shape:SolidMolecular weight:374.34HO-3867
CAS:<p>HO-3867, an analog of curcumin, is a sspecific STAT3 inhibitor.</p>Formula:C28H30F2N2O2Purity:91.18% - 99.21%Color and Shape:SolidMolecular weight:464.55S3I-201
CAS:<p>S3I-201 (S3I-201) is a selective Stat3 inhibitor (IC50: 86±33 μM) and low effect towards STAT1/5.</p>Formula:C16H15NO7SPurity:97.83%Color and Shape:SolidMolecular weight:365.36Morusin
CAS:<p>Morusin shows anti-tumor, antioxidant, and anti-inflammatory properties by inhibiting STAT3, NFκB, and inducing apoptosis.</p>Formula:C25H24O6Purity:98.68% - 99.8%Color and Shape:SolidMolecular weight:420.45STAT5-IN-1
CAS:<p>STAT5-IN-1 (STAT5 Inhibitor) is a cell-permeable inhibitor which suppresses Stat5 via binding to the SH2 domain.</p>Formula:C16H11N3O3Purity:99.44% - ≥95%Color and Shape:SolidMolecular weight:293.28Napabucasin
CAS:<p>Napabucasin (BBI608) is an orally available Stat3 and Y cell stemness inhibitor.</p>Formula:C14H8O4Purity:98.43% - 99.85%Color and Shape:SolidMolecular weight:240.21Arnicolide D
CAS:<p>Arnicolide D is a sesquiterpene lactone.</p>Formula:C19H24O5Purity:96.66%Color and Shape:SolidMolecular weight:332.39Garcinone D
CAS:<p>Garcinone D is cytotoxic to CEM-SS cells (IC50=3.2 µg/ml), inhibits aromatase and p65 activation (IC50=3.2 µM).</p>Formula:C24H28O7Purity:99.94%Color and Shape:SolidMolecular weight:428.47Triacetylresveratrol
CAS:<p>Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity, it inhibits the phosphorylation of STAT3 and NFκB in pancreatic cancer cells.</p>Formula:C20H18O6Purity:99.81%Color and Shape:Off White PowderMolecular weight:354.35HJC0152 hydrochloride
CAS:<p>HJC0152 hydrochloride (HJC0152) is a signal transducer and activator of transcription 3 (STAT3) inhibitor.</p>Formula:C15H14Cl3N3O4Purity:99.01% - 99.06%Color and Shape:SolidMolecular weight:406.64Nitidine chloride
CAS:<p>1.</p>Formula:C21H18ClNO4Purity:96.59% - 98.91%Color and Shape:SolidMolecular weight:383.82RO8191
CAS:<p>RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor.</p>Formula:C14H5F6N5OPurity:98% - 98.85%Color and Shape:SolidMolecular weight:373.21Balsalazide disodium dihydrate
CAS:<p>Balsalazide sodium hydrate treats mild-to-moderate ulcerative colitis; higher doses enhance remission maintenance; it's safe and effective.</p>Formula:C17H17N3Na2O8Purity:98.95% - 99.49%Color and Shape:Yellow To Orange Crystalline PowderMolecular weight:437.31BP-1-102
CAS:<p>BP-1-102 is an orally active, effective and specific STAT3 inhibitor.</p>Formula:C29H27F5N2O6SPurity:99.25% - 99.44%Color and Shape:SolidMolecular weight:626.59ML116
CAS:<p>ML116 is a potent and selective STAT3 inhibitor.</p>Formula:C18H19N3SPurity:99.49%Color and Shape:SolidMolecular weight:309.43Picroside I
CAS:<p>Picroside I (6'-Cinnamoylcatalpol), a hepatoprotective agent, is reported to be antimicrobial and used against hepatitis B.</p>Formula:C24H28O11Purity:99.70%Color and Shape:SolidMolecular weight:492.47SH5-07
CAS:<p>SH5-07 is a hydroxamic acid-based Stat3 inhibitor (IC50: 3.9 μM).</p>Formula:C29H28F5N3O5SPurity:95.54%Color and Shape:SolidMolecular weight:625.61FLLL32
CAS:<p>FLLL32 is an effective JAK2/STAT3 inhibitor (IC50 of <5 μM).</p>Formula:C28H32O6Purity:97% - 97.90%Color and Shape:SolidMolecular weight:464.552-(1,8-naphthyridin-2-yl)phenol
CAS:<p>2-NP is a STAT1 enhancer.</p>Formula:C14H10N2OPurity:99.33% - 99.82%Color and Shape:SolidMolecular weight:222.24TPCA-1
CAS:<p>TPCA-1 (TPCA1) is an effective and specific IKK-2 inhibitor (IC50: 17.9 nM); shows >22-fold selectivity over IKK-1 and >550-fold selectivity over others kinases</p>Formula:C12H10FN3O2SPurity:95.03% - 97.86%Color and Shape:SolidMolecular weight:279.29
