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STAT

STAT

STAT proteins are critical components of the JAK/STAT signaling pathway, which transmits extracellular signals from cytokines and growth factors to the cell nucleus, influencing gene expression. STAT proteins are involved in regulating immune responses, cell growth, differentiation, and survival. Dysregulation of STAT signaling is implicated in various diseases, including cancer, autoimmune disorders, and chronic inflammation. At CymitQuimica, we provide a comprehensive range of STAT pathway modulators to support your research in signal transduction, immunology, and therapeutic development.

Found 109 products for "STAT".

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  • Saikosaponin D
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    Saikosaponin D

    CAS:
    Saikosaponin D is a novel SERCA inhibitor by inhibiting NF-κB and STAT3 signaling to protect against acetaminophen-induced hepatotoxicity.
    Formula:C42H68O13
    Purity:98.34% - 99.73%
    Color and Shape:White Solid
    Molecular weight:780.9815

    Ref: TM-T3913

  • Protosappanin A
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    Protosappanin A

    CAS:
    Protosappanin A combats brain inflammation, suppresses rat heart transplant rejection, fights MRSA, and inhibits HIV with a 12.6 uM IC50.
    Formula:C15H12O5
    Purity:99.42% - 99.82%
    Color and Shape:White Solid
    Molecular weight:272.2528

    Ref: TM-TJS1779

  • AS1517499
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    AS1517499

    CAS:
    AS1517499 is a blood-brain barrier permeable inhibitor of STAT6 phosphorylation (IC50= 21 nM). High-Quality, Low-Cost!
    Formula:C20H20ClN5O2
    Purity:98.27% - 99.3%
    Color and Shape:Solid
    Molecular weight:397.858

    Ref: TM-T4476

  • Panaxadiol
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    Panaxadiol

    CAS:
    Panaxadiol (20(R)-Panaxadiol) is a novel antitumor agent extracted from the Chinese medical herb Panax ginseng.
    Formula:C30H52O3
    Purity:98% - 99.9%
    Color and Shape:Solid
    Molecular weight:460.7321

    Ref: TM-T2763

  • 2-(1,8-naphthyridin-2-yl)phenol
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    2-(1,8-naphthyridin-2-yl)phenol

    CAS:
    2-NP is a STAT1 enhancer.
    Formula:C14H10N2O
    Purity:99.82% - 99.94%
    Color and Shape:Solid
    Molecular weight:222.242

    Ref: TM-T2168

  • BD750
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    BD750

    CAS:
    BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 of 1.5 μM and 1.1 μM in
    Formula:C14H13N3OS
    Purity:99.02%
    Color and Shape:Solid
    Molecular weight:271.338

    Ref: TM-T8546

  • FLLL32
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    FLLL32

    CAS:
    FLLL32 is an effective JAK2/STAT3 inhibitor (IC50 of <5 μM).
    Formula:C28H32O6
    Purity:97.90% - 99.10%
    Color and Shape:Solid
    Molecular weight:464.5501

    Ref: TM-T6838

  • SH5-07
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    SH5-07

    CAS:
    SH5-07 is a hydroxamic acid-based Stat3 inhibitor (IC50: 3.9 μM).
    Formula:C29H28F5N3O5S
    Purity:95.54%
    Color and Shape:Solid
    Molecular weight:625.607

    Ref: TM-TQ0052

  • Astaxanthin
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    Astaxanthin

    CAS:
    Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.
    Formula:C40H52O4
    Purity:95.10% - 99.79%
    Color and Shape:Solid
    Molecular weight:596.8385

    Ref: TM-T3138

  • Tetramethylcurcumin
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    Tetramethylcurcumin

    CAS:
    Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it also
    Formula:C25H28O6
    Purity:99.33% - 99.94%
    Color and Shape:Yellow Solid
    Molecular weight:424.4862

    Ref: TM-TN2269

  • Stattic
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    Stattic

    CAS:
    Stattic (STAT3 Inhibitor V) is a STAT3 inhibitor (IC50=5.1 μM) that selectively inhibits STAT3 activation, dimerization, and nuclear translocation.
    Formula:C8H5NO4S
    Purity:98.32% - 99.76%
    Color and Shape:Solid
    Molecular weight:211.195

    Ref: TM-T6308

  • AS1810722
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    AS1810722

    CAS:
    AS1810722, a fused bicyclic pyrimidine derivative, is an orally active and potent inhibitor of STAT6, demonstrating an IC50 of 1.9 nM.
    Formula:C25H25F2N7O
    Purity:99.13%
    Color and Shape:Solid
    Molecular weight:477.5091

    Ref: TM-T9043

  • HJC0152 hydrochloride
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    HJC0152 hydrochloride

    CAS:
    HJC0152 hydrochloride (HJC0152) is a signal transducer and activator of transcription 3 (STAT3) inhibitor.
    Formula:C15H14Cl3N3O4
    Purity:99.01% - 99.06%
    Color and Shape:Solid
    Molecular weight:406.648

    Ref: TM-T4234

  • 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea
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    1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea

    CAS:
    SC-1 is a a derivative of the multiple tyrosine kinase inhibitor sorafenib.
    Formula:C21H13ClF3N3O2
    Purity:97.56%
    Color and Shape:White Solid
    Molecular weight:431.795

    Ref: TM-T22424

  • Atractylenolide I
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    Atractylenolide I

    CAS:
    Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to paclitaxel.
    Formula:C15H18O2
    Purity:97.55% - 99.92%
    Color and Shape:White Solid
    Molecular weight:230.3022

    Ref: TM-T5S0167

  • Picroside I
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    Picroside I

    CAS:
    Picroside I (6'-Cinnamoylcatalpol), a hepatoprotective agent, is reported to be antimicrobial and used against hepatitis B.
    Formula:C24H28O11
    Purity:99.70% - 99.93%
    Color and Shape:White Solid
    Molecular weight:492.4725

    Ref: TM-T2787

  • Casticin
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    Casticin

    CAS:
    Casticin combats vascular inflammation by blocking ROS-NF-κB and could lead in prostate cancer treatment.
    Formula:C19H18O8
    Purity:99.59% - ≥95%
    Color and Shape:Solid
    Molecular weight:374.3414

    Ref: TM-T6S1373

  • Fraxinellone
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    Fraxinellone

    CAS:
    1.
    Formula:C14H16O3
    Purity:99.35% - 99.88%
    Color and Shape:Yellow Solid
    Molecular weight:232.275

    Ref: TM-T6S0071

  • ML116
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    ML116

    CAS:
    ML116 is a potent and selective STAT3 inhibitor.
    Formula:C18H19N3S
    Purity:99.49%
    Color and Shape:Solid
    Molecular weight:309.429

    Ref: TM-T8597

  • Corylifol A
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    Corylifol A

    CAS:
    1.
    Formula:C25H26O4
    Purity:97.19% - 99.5%
    Color and Shape:Solid
    Molecular weight:390.4715

    Ref: TM-T4S0145