MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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Prosaptide TX14(A) acetate
Prosaptide TX14(A) acetate is a potent GPR37L1 and GPR37 agonist. Prosaptide Tx14(A) TFA increases both …
Formula:
C71H114N16O28
Purity:
95.29%
Color and Shape:
Solid
Molecular weight:
1639.76
Ref: TM-TP1970L
| 1mg | 144.00 € | ||
| 5mg | 343.00 € | ||
| 10mg | 512.00 € | ||
| 25mg | 824.00 € | ||
| 50mg | 1,116.00 € | ||
| 100mg | 1,529.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Ravoxertinib
CAS:1453848-26-4
Ravoxertinib (GDC-0994) is an effective and orally available ERK1/2 inhibitor (IC50: 1.1/0.3 nM).
Formula:
C21H18ClFN6O2
Purity:
98% - 99.87%
Color and Shape:
Solid
Molecular weight:
440.86
Ref: TM-T6511
| 1mg | 40.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 171.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 412.00 € | ||
| 1mL*10mM (DMSO) | 93.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Doramapimod
CAS:285983-48-4
Doramapimod (BIRB 796) is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but …
Formula:
C31H37N5O3
Purity:
97.73% - 99.65%
Color and Shape:
Solid
Molecular weight:
527.66
Ref: TM-T6277
| 1g | 552.00 € | ||
| 5mg | 36.00 € | ||
| 10mg | 54.00 € | ||
| 25mg | 78.00 € | ||
| 50mg | 90.00 € | ||
| 100mg | 124.00 € | ||
| 200mg | 220.00 € | ||
| 500mg | 371.00 € | ||
| 1mL*10mM (DMSO) | 44.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
LY-2584702 tosylate salt
CAS:1082949-68-5
LY-2584702 tosylate salt is a selective, ATP-competitive p70S6K inhibitor, used in trials studying the treatment …
Formula:
C28H27F4N7O3S
Purity:
98.23% - 98.5%
Color and Shape:
Solid
Molecular weight:
617.62
Ref: TM-T1746
| 1mg | 37.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 352.00 € | ||
| 100mg | 500.00 € | ||
| 500mg | 1,072.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
LM22B-10
CAS:342777-54-2
LM22B-10 is an activator of TrkB/TrkC neurotrophin receptor and can induce TrkB, TrkC, ERK and …
Formula:
C27H33ClN2O4
Purity:
98.19%
Color and Shape:
Solid
Molecular weight:
485.01
Ref: TM-T4496
| 1mg | 39.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 132.00 € | ||
| 25mg | 272.00 € | ||
| 50mg | 429.00 € | ||
| 100mg | 682.00 € | ||
| 1mL*10mM (DMSO) | 132.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
PD318088
CAS:391210-00-7
PD318088 is a non-ATP competitive allosteric MEK1/2 inhibitor, binding simultaneously with ATP in a region …
Formula:
C16H13BrF3IN2O4
Purity:
99.81%
Color and Shape:
Solid
Molecular weight:
561.09
Ref: TM-T6152
| 1mg | 51.00 € | ||
| 5mg | 105.00 € | ||
| 10mg | 163.00 € | ||
| 25mg | 332.00 € | ||
| 50mg | 500.00 € | ||
| 100mg | 759.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
HPK1-IN-7
CAS:2320462-65-3
HPK1-IN-7 is an orally active HPK1 inhibitor. It shows selectivity against IRAK4 (59 nM) and …
Formula:
C24H22N6O4
Purity:
99.31%
Color and Shape:
Solid
Molecular weight:
458.47
Ref: TM-T9470
| 1mg | 82.00 € | ||
| 5mg | 167.00 € | ||
| 10mg | 266.00 € | ||
| 25mg | 433.00 € | ||
| 50mg | 593.00 € | ||
| 100mg | 817.00 € | ||
| 200mg | 1,080.00 € | ||
| 1mL*10mM (DMSO) | 167.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
SD-169
CAS:1670-87-7
SD-169 (SD 169) is a selective and ATP competitive the MAP kinases p38α and p38β …
Formula:
C9H8N2O
Purity:
98.60%
Color and Shape:
Solid
Molecular weight:
160.17
Ref: TM-T7661
| 25mg | 36.00 € | ||
| 50mg | 51.00 € | ||
| 100mg | 78.00 € | ||
| 200mg | 102.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
K-Ras-IN-1
CAS:84783-01-7
K-Ras-IN-1 is a K-Ras inhibitor.
Formula:
C11H13NOS
Purity:
98.72%
Color and Shape:
Solid
Molecular weight:
207.29
Ref: TM-T5469
| 2mg | 45.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 99.00 € | ||
| 25mg | 178.00 € | ||
| 50mg | 277.00 € | ||
| 100mg | 415.00 € | ||
| 200mg | 574.00 € | ||
| 1mL*10mM (DMSO) | 75.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
(E/Z)-BIX02188
CAS:1094614-84-2
BIX02188 inhibits MEK5 (IC50: 4.3 nM) and ERK5 (810 nM) but not MEK1/2, JNK2, or …
Formula:
C25H24N4O2
Purity:
97.39% - 98.38%
Color and Shape:
Solid
Molecular weight:
412.48
Ref: TM-T6324
| 1mg | 51.00 € | ||
| 2mg | 65.00 € | ||
| 5mg | 125.00 € | ||
| 10mg | 226.00 € | ||
| 25mg | 341.00 € | ||
| 50mg | 512.00 € | ||
| 100mg | 737.00 € | ||
| 1mL*10mM (DMSO) | 142.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
MRTX1133
CAS:2621928-55-8
View and buy MRTX1133 from TargetMol.MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS …
Formula:
C33H31F3N6O2
Purity:
97.39% - 99.10%
Color and Shape:
Solid
Molecular weight:
600.63
Ref: TM-T9303
| 1mg | 185.00 € | ||
| 5mg | 397.00 € | ||
| 10mg | 607.00 € | ||
| 25mg | 932.00 € | ||
| 50mg | 1,318.00 € | ||
| 100mg | 1,794.00 € | ||
| 1mL*10mM (DMSO) | 523.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
AMG 900
CAS:945595-80-2
AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with …
Formula:
C28H21N7OS
Purity:
98.35% - 98.9%
Color and Shape:
Solid
Molecular weight:
503.58
Ref: TM-T6380
| 1mg | 52.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 163.00 € | ||
| 25mg | 295.00 € | ||
| 50mg | 457.00 € | ||
| 100mg | 670.00 € | ||
| 500mg | 1,384.00 € | ||
| 1mL*10mM (DMSO) | 103.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Bisabolangelone
CAS:30557-81-4
Bisabolangelone: anti-tumor, anti-inflammatory, anti-microbial, antioxidant, blocks MAPK/NF-κB in dendritic cells.
Formula:
C15H20O3
Purity:
98.91%
Color and Shape:
Solid
Molecular weight:
248.32
Ref: TM-TN1445
| 1mg | 52.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 158.00 € | ||
| 25mg | 258.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 94.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
KO-947
CAS:1695533-89-1
KO-947 is a potent and specific inhibitor of ERK1/2 kinases.
Formula:
C21H17N5O
Purity:
96.81%
Color and Shape:
Solid
Molecular weight:
355.39
Ref: TM-TQ0005
| 1mg | 51.00 € | ||
| 5mg | 100.00 € | ||
| 10mg | 159.00 € | ||
| 25mg | 313.00 € | ||
| 50mg | 501.00 € | ||
| 100mg | 791.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
ML-098
CAS:878978-76-8
ML-098 (CID-7345532) is an activator of the GTP-binding protein Rab7 (EC50: 77.6 nM).
Formula:
C19H19NO3
Purity:
99.06% - 99.52%
Color and Shape:
Solid
Molecular weight:
309.36
Ref: TM-T4619
| 1mg | 39.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 196.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 386.00 € | ||
| 500mg | 913.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
SM-7368
CAS:380623-76-7
The NF-κB Activation Inhibitor III, controls the biological activity of NF-κB. It is primarily used …
Formula:
C10H5ClN4O5S
Purity:
99.64% - 99.64%
Color and Shape:
Solid
Molecular weight:
328.69
Ref: TM-T22115
| 5mg | 45.00 € | ||
| 10mg | 72.00 € | ||
| 25mg | 130.00 € | ||
| 50mg | 182.00 € | ||
| 100mg | 272.00 € | ||
| 200mg | 397.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
N-Feruloyloctopamine
CAS:66648-44-0
N-Feruloyloctopamine is a natural product.
Formula:
C18H19NO5
Purity:
99.67%
Color and Shape:
Solid
Molecular weight:
329.35
Ref: TM-TN1968
| 1mg | 88.00 € | ||
| 5mg | 203.00 € | ||
| 10mg | 297.00 € | ||
| 25mg | 500.00 € | ||
| 50mg | 723.00 € | ||
| 100mg | 1,013.00 € | ||
| 1mL*10mM (DMSO) | 170.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
1588-A4
CAS:1698027-20-1
1588-A4 (ARS-1620 Intermediate) is an intermediate of ARS-1620 which is an atropisomeric selective KRASG12C inhibitor …
Formula:
C17H19BrClFN4O2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
445.71
Ref: TM-T22249
| 1mg | 81.00 € | ||
| 2mg | 93.00 € | ||
| 5mg | 152.00 € | ||
| 10mg | 214.00 € | ||
| 25mg | 356.00 € | ||
| 50mg | 509.00 € | ||
| 100mg | 692.00 € | ||
| 200mg | 903.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Raf inhibitor 1 dihydrochloride
CAS:1191385-19-9
Raf inhibitor 1 dihydrochloride (B-Raf inhibitor 1 dihydrochloride) is a potent and selective B-Raf inhibitor.
Formula:
C26H19ClN8HCl
Purity:
98.19% - 98.44%
Color and Shape:
Solid
Molecular weight:
551.86
Ref: TM-T4167
| 1mg | 49.00 € | ||
| 2mg | 65.00 € | ||
| 5mg | 105.00 € | ||
| 10mg | 182.00 € | ||
| 25mg | 304.00 € | ||
| 50mg | 450.00 € | ||
| 100mg | 659.00 € | ||
| 500mg | 1,347.00 € | ||
| 1mL*10mM (DMSO) | 190.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Losmapimod
CAS:585543-15-3
Losmapimod (GSK-AHAB) (GW856553X; SB856553; GSK-AHAB) is a specific, potent, and orally active p38 MAPK inhibitor …
Formula:
C22H26FN3O2
Purity:
98.56% - 99.05%
Color and Shape:
Solid
Molecular weight:
383.46
Ref: TM-T2277
| 2mg | 35.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 77.00 € | ||
| 25mg | 137.00 € | ||
| 50mg | 222.00 € | ||
| 100mg | 398.00 € | ||
| 500mg | 906.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
