MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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GDC-0879
CAS:905281-76-7
GDC-0879 (AR-00341677) is a novel, potent and selective B-Raf inhibitor with IC50 of 0.13 nM …
Formula:
C19H18N4O2
Purity:
95.76%
Color and Shape:
Solid
Molecular weight:
334.37
Ref: TM-T6320
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 346.00 € | ||
| 100mg | 555.00 € | ||
| 200mg | 789.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
MAPK13-IN-1
CAS:229002-10-2
MAPK13-IN-1 is a potent MAPK13 (p38δ) inhibitor (IC50: 620 nM).
Formula:
C20H23N5O2
Purity:
99.55%
Color and Shape:
Solid
Molecular weight:
365.43
Ref: TM-T11943
| 1mg | 98.00 € | ||
| 2mg | 144.00 € | ||
| 5mg | 233.00 € | ||
| 10mg | 351.00 € | ||
| 25mg | 607.00 € | ||
| 50mg | 879.00 € | ||
| 100mg | 1,267.00 € | ||
| 500mg | 2,565.00 € | ||
| 1mL*10mM (DMSO) | 257.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
B-Raf IN 13
CAS:2573782-74-6
B-Raf IN 13 is a potent B-Raf inhibitor with anticancer activity.B-Raf IN 13 has an …
Formula:
C19H19ClFN3O4S
Purity:
95.83% - 98.39%
Color and Shape:
Soild
Molecular weight:
439.89
Ref: TM-T67862
| 25mg | 1,410.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
EB1
CAS:42951-68-8
EB1 is an MNK kinase inhibitor that inhibits cancer cell growth, promotes apoptosis, and inhibits …
Formula:
C18H14N4
Purity:
99.82%
Color and Shape:
Liquid
Molecular weight:
286.33
Ref: TM-T73582
| 1g | 3,239.00 € | ||
| 1mg | 74.00 € | ||
| 5mg | 157.00 € | ||
| 10mg | 221.00 € | ||
| 25mg | 367.00 € | ||
| 50mg | 551.00 € | ||
| 100mg | 785.00 € | ||
| 500mg | 2,181.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
PAF (C16)
CAS:74389-68-7
PAF (C16) is a potent MAPK and MEK/ERK activator that induces increased vascular permeability.
Formula:
C26H54NO7P
Purity:
98%
Color and Shape:
Solid
Molecular weight:
523.68
Ref: TM-T21547
| 1mg | 73.00 € | ||
| 5mg | To inquire |
Estimated delivery in United States, on Tuesday 4 Feb 2025
MNK1/2-IN-5
CAS:1426928-20-2
MNK1/2-IN-5 is a potent and selective MNK1/2 inhibitor with anticancer activity and can be used …
Formula:
C17H16N4O2
Color and Shape:
Liquid
Molecular weight:
308.33
Ref: TM-T60733
| 1mg | 61.00 € | ||
| 5mg | 132.00 € | ||
| 10mg | 203.00 € | ||
| 25mg | 342.00 € | ||
| 50mg | 504.00 € | ||
| 100mg | 718.00 € | ||
| 500mg | 1,450.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
AL 8697
CAS:1057394-06-5
AL 8697 is a selective p38α MAPK inhibitor (IC50 = 6 nM) with 14-fold selectivity …
Formula:
C21H21F3N4O
Purity:
98.96% - 99.26%
Color and Shape:
Solid
Molecular weight:
402.41
Ref: TM-T10277
| 1mg | 69.00 € | ||
| 5mg | 143.00 € | ||
| 10mg | 202.00 € | ||
| 25mg | 341.00 € | ||
| 50mg | 484.00 € | ||
| 100mg | 665.00 € | ||
| 500mg | To inquire | ||
| 1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
UR13870
CAS:755753-89-0
UR-13870 (Org 48762-0) is a p38 MAPK inhibitor that prevents bone damage in collagen-induced arthritis …
Formula:
C24H16F2N4
Purity:
100% - 98.92%
Color and Shape:
Solid
Molecular weight:
398.41
Ref: TM-T29071
| 1mg | 210.00 € | ||
| 5mg | 532.00 € | ||
| 10mg | 729.00 € | ||
| 25mg | 1,158.00 € | ||
| 50mg | 1,498.00 € | ||
| 100mg | 1,934.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
p38 MAPK Inhibitor
CAS:219138-24-6
p38 MAPK inhibitor is a potent inhibitor of p38 MAP kinase (IC50 = 35 nM). …
Formula:
C20H13ClFN3O
Purity:
99.24%
Color and Shape:
Liquid
Molecular weight:
365.79
Ref: TM-T36010
| 1mg | 94.00 € | ||
| 5mg | 290.00 € | ||
| 10mg | 452.00 € | ||
| 25mg | 660.00 € | ||
| 50mg | 906.00 € | ||
| 100mg | 1,204.00 € | ||
| 200mg | 1,639.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
MEK-IN-1
CAS:870600-45-6
MEK-IN-1 is a MEK inhibitor.
Formula:
C24H20N4O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
428.44
Ref: TM-T10675
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
ZINC12409120
CAS:1010888-06-8
ZINC12409120 (R-4584) is a selective ERK inhibitor.ZINC12409120 inhibits ERK with an IC50 of 5.0 μM.ZINC12409120 …
Formula:
C20H16N4O2
Purity:
98.69% - 99.84%
Color and Shape:
Liquid
Molecular weight:
344.37
Ref: TM-T61122
| 1mg | 325.00 € | ||
| 5mg | 769.00 € | ||
| 10mg | 1,049.00 € | ||
| 25mg | 1,476.00 € | ||
| 50mg | 1,838.00 € | ||
| 100mg | 2,336.00 € | ||
| 500mg | 4,549.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
GSK2008607
CAS:1244644-50-5
GSK2008607 is a potent B-RafV600E inhibitor with anticancer activity and can be used to study …
Formula:
C31H28F3N7O3S2
Purity:
99%
Color and Shape:
Solid
Molecular weight:
667.72
Ref: TM-T27454
| 1mg | 325.00 € | ||
| 5mg | 772.00 € | ||
| 10mg | 1,056.00 € | ||
| 25mg | 1,476.00 € | ||
| 50mg | 1,845.00 € | ||
| 100mg | 2,322.00 € | ||
| 500mg | 4,547.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
MEK-IN-4
CAS:297744-42-4
MEK-IN-4 is a MEK inhibitor that can be used to study inflammatory diseases and cancer.
Formula:
C21H18N4OS
Purity:
98.67% - 99.26%
Color and Shape:
Solid
Molecular weight:
374.46
Ref: TM-T28012
| 1mg | 327.00 € | ||
| 5mg | 772.00 € | ||
| 25mg | 1,410.00 € | ||
| 50mg | 1,850.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
Iroxanadine
CAS:203805-20-3
Iroxanadine (BRX-005) is a Novel small molecule MAPK p38 inhibitor that induces phosphorylation of p38 …
Formula:
C14H20N4O
Purity:
100% - 97.92%
Color and Shape:
Liquid
Molecular weight:
260.33
Ref: TM-T27627
| 1mg | 141.00 € | ||
| 5mg | 325.00 € | ||
| 10mg | 496.00 € | ||
| 25mg | 798.00 € | ||
| 50mg | 1,100.00 € | ||
| 100mg | 1,486.00 € | ||
| 500mg | 2,960.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
Lucidenic acid F
CAS:98665-18-0
Lucidenic acid F as a modulator of JNK and p38, it shows potent inhibitory effects …
Formula:
C27H36O6
Purity:
98%
Color and Shape:
Solid
Molecular weight:
456.57
Ref: TM-TMA1004
| 25mg | To inquire |
Estimated delivery in United States, on Tuesday 4 Feb 2025
J30-8
CAS:2366255-71-0
J30-8 is a JNK3 inhibitor (IC50: 40 nM) with neuroprotective activity and can be used …
Formula:
C17H9ClFN3O2S
Purity:
99.90%
Color and Shape:
Solid
Molecular weight:
373.79
Ref: TM-T11702
| 1mg | 38.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
Jolkinolide B
CAS:37905-08-1
Jolkinolide B is a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud.
Formula:
C20H26O4
Purity:
99.39%
Color and Shape:
Solid
Molecular weight:
330.42
Ref: TM-T2S1040
| 1mg | 65.00 € | ||
| 5mg | 141.00 € | ||
| 10mg | 212.00 € | ||
| 25mg | 361.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
AMG-548
CAS:864249-60-5
AMG-548, oral p38α inhibitor (Ki=0.5 nM), >1000x selectivity over p38γ/δ, blocks TNFα (IC50=3 nM), also …
Formula:
C29H27N5O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
461.56
Ref: TM-T10298L
| 10mg | 123.00 € | ||
| 25mg | 280.00 € | ||
| 100mg | 1,077.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
AKP-001
CAS:897644-83-6
AKP-001 is a selective inhibitor of MAPK of the p38α isoform and is used in …
Formula:
C21H13ClF2N4O2
Purity:
99.50% - 99.92%
Color and Shape:
Solid
Molecular weight:
426.8
Ref: TM-T25015
| 25mg | 1,410.00 € | ||
| 50mg | 1,845.00 € | ||
| 100mg | 2,329.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
mSIRK
CAS:593267-11-9
mSIRK (G-Protein βγ Binding Peptide) is an ERK1 and ERK2 dual activator that promotes alpha-subunit …
Formula:
C93H150N20O25
Purity:
99.26%
Color and Shape:
Liquid
Molecular weight:
1948.31
Ref: TM-T80548
| 1mg | 46.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 116.00 € | ||
| 25mg | 181.00 € | ||
| 50mg | 271.00 € | ||
| 100mg | 413.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
