MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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RMC-0331
CAS:2488788-52-7
RMC-0331 (RM-023) is an oral SOS1 inhibitor with potential to block RAS activation and anticancer …
Formula:
C22H25ClF3N5O3
Purity:
99.81%
Color and Shape:
Solid
Molecular weight:
499.91
Ref: TM-T38170
| 1mg | 143.00 € | ||
| 2mg | 207.00 € | ||
| 5mg | 346.00 € | ||
| 10mg | 616.00 € | ||
| 25mg | 1,273.00 € | ||
| 50mg | 1,977.00 € | ||
| 100mg | 2,935.00 € | ||
| 1mL*10mM (DMSO) | 375.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
KRAS G12D inhibitor 14
CAS:2765254-39-3
KRAS G12D inhibitor 14 is a potent inhibitor of KRAS G12D that binds KRAS G12D …
Formula:
C20H19F3N4OS
Purity:
99.39%
Color and Shape:
Liquid
Molecular weight:
420.45
Ref: TM-T62228
| 1mg | 278.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
BSJ-04-122
CAS:2513289-74-0
BSJ-04-122: MKK4/7 inhibitor with IC50s of 4 nM & 181 nM, used in cancer research.
Formula:
C15H12ClN5O
Purity:
97.58%
Color and Shape:
Odour Color
Molecular weight:
313.74
Ref: TM-T73182
| 1mg | 41.00 € | ||
| 5mg | 81.00 € | ||
| 10mg | 116.00 € | ||
| 25mg | 226.00 € | ||
| 50mg | 363.00 € | ||
| 100mg | 581.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
JAK2/FLT3-IN-1
CAS:2387765-27-5
Potent, orally active JAK2/FLT3-IN-1: Anti-cancer, dual JAK2/FLT3 inhibitor with low IC50s for JAK2/FLT3/JAK1/JAK3.
Formula:
C25H34FN7O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
467.58
Ref: TM-T11707
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
FR 167653
CAS:158876-66-5
FR 167653 sulfate, an orally active and selective inhibitor of p38 MAPK, is effective in …
Formula:
C24H20FN5O6S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
525.51
Ref: TM-T11327
| 5mg | 477.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
KRas G12C inhibitor 3
CAS:2206735-75-1
KRas G12C inhibitor 3 is a compound that inhibits KRas G12C.
Formula:
C32H36ClN7O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
586.13
Ref: TM-T11778
| 25mg | 1,406.00 € | ||
| 50mg | 1,847.00 € | ||
| 100mg | 2,331.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
LY-2584702 hydrochloride
CAS:1082948-81-9
Ly-2584702 hydrochloride is a p70S6K selective ATP competitive inhibitor with IC50 of 4 nM.In the …
Formula:
C21H20ClF4N7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
481.88
Ref: TM-T11900
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
RLX-33
CAS:2784577-71-3
RLX-33 blocks RXFP3 and relaxin 3 effects, controls food intake in rats, and may help …
Formula:
C24H19ClN4O4
Purity:
99.82%
Color and Shape:
Liquid
Molecular weight:
462.89
Ref: TM-T62929
| 1mg | 81.00 € | ||
| 5mg | 174.00 € | ||
| 10mg | 277.00 € | ||
| 25mg | 441.00 € | ||
| 50mg | 630.00 € | ||
| 100mg | 847.00 € | ||
| 500mg | 1,653.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
SOS1-IN-15
CAS:2793404-47-2
SOS1-IN-15 is an orally active and potent SOS1 inhibitor with potential antitumor activity.SOS1-IN-15 is used …
Formula:
C28H27F3N6O2
Purity:
98.32%
Color and Shape:
Liquid
Molecular weight:
536.548
Ref: TM-T73164
| 1mg | 128.00 € | ||
| 5mg | 308.00 € | ||
| 10mg | 504.00 € | ||
| 25mg | 925.00 € | ||
| 50mg | 1,639.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
KRAS inhibitor-7
CAS:2022986-68-9
KRAS inhibitor-7 is a potent KRAS G12C inhibitor.
Formula:
C26H27ClF2N6O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
528.98
Ref: TM-T11774
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
MCP110
CAS:521310-51-0
MCP110 is an inhibitor of the interaction of Ras with Raf-1 and can be used …
Formula:
C33H36N2O3
Purity:
97.18%
Color and Shape:
Oil
Molecular weight:
508.65
Ref: TM-T24437
| 1mg | 37.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 165.00 € | ||
| 25mg | 284.00 € | ||
| 50mg | 411.00 € | ||
| 100mg | 547.00 € | ||
| 500mg | 1,107.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
KRas G12C inhibitor 4
CAS:2206736-07-2
KRas G12C inhibitor 4 is a compound that inhibits KRas G12C.
Formula:
C33H38ClN7O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
600.15
Ref: TM-T11779
| 25mg | 1,406.00 € | ||
| 50mg | 1,845.00 € | ||
| 100mg | 2,329.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
SR-3306
CAS:1128096-91-2
SR-3306 is a brain-penetrant and selective pan-JNK (JNK1/2/3) inhibitor with IC50 values of 67 nM, …
Formula:
C28H26N8O
Purity:
99.50% - 99.81%
Color and Shape:
Solid
Molecular weight:
490.56
Ref: TM-T16927
| 1mg | 52.00 € | ||
| 5mg | 101.00 € | ||
| 10mg | 158.00 € | ||
| 25mg | 296.00 € | ||
| 50mg | 537.00 € | ||
| 100mg | 862.00 € | ||
| 500mg | 1,726.00 € | ||
| 1mL*10mM (DMSO) | 114.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
EO-1606
CAS:344457-87-0
EO-1606 is a p38MAP kinase inhibitor with anti-inflammatory activity and may be used in studies …
Formula:
C21H17ClFNO
Purity:
98.84% - 99.27%
Color and Shape:
Solid
Molecular weight:
353.82
Ref: TM-T31645
| 1mg | 273.00 € | ||
| 5mg | 673.00 € | ||
| 10mg | 920.00 € | ||
| 25mg | 1,416.00 € | ||
| 50mg | 1,845.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
Compound 3344
CAS:2368246-78-8
3344 is an inhibitor of KRAS-effector interactions,with an affnity of 126nm.
Formula:
C24H26N2O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
390.47
Ref: TM-T9184
| 25mg | 862.00 € | ||
| 50mg | 1,120.00 € | ||
| 100mg | 1,681.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
TH-Z835
CAS:2766209-50-9
TH-Z835 is a selective inhibitor for the KRAS (G12D) mutation, demonstrating an inhibitory concentration (IC50) …
Formula:
C30H38N6O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
498.66
Ref: TM-T78661
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
HS-276
CAS:2767422-72-8
HS-276, a selective oral TAK1 inhibitor (Ki: 2.5 nM), also targets CLK2, GCK, ULK2, MAP4K5; …
Formula:
C24H29N5O2
Purity:
98.07%
Color and Shape:
Liquid
Molecular weight:
419.52
Ref: TM-T62209
| 1mg | 88.00 € | ||
| 5mg | 198.00 € | ||
| 10mg | 310.00 € | ||
| 25mg | 547.00 € | ||
| 50mg | 794.00 € | ||
| 100mg | 1,103.00 € | ||
| 1mL*10mM (DMSO) | 222.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
p38α inhibitor 4
CAS:1262406-08-5
p38α inhibitor 4 is a selective MAPK p38α inhibitor, which is used to study diabetes, …
Formula:
C14H7F6N3O
Purity:
99.79%
Color and Shape:
Liquid
Molecular weight:
347.215
Ref: TM-T78652
| 1mg | 279.00 € | ||
| 5mg | 686.00 € | ||
| 10mg | 938.00 € | ||
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
JNK-IN-11
CAS:676594-38-0
JNK-IN-11 inhibits JNK1/2/3 (IC50: 2.2/21.4/1.8 μM); promising for Alzheimer's/Parkinson's research.
Formula:
C12H11NO3S2
Purity:
98.82%
Color and Shape:
Liquid
Molecular weight:
281.35
Ref: TM-T60534
| 1mg | 46.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 138.00 € | ||
| 25mg | 269.00 € | ||
| 50mg | 397.00 € | ||
| 100mg | 578.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
Antifungal agent 46
CAS:2842067-19-8
Compound 2f (Antifungal Agent 46) is a potent antifungal that inhibits Ras signaling by targeting …
Formula:
C26H28BrF3N4O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
565.43
Ref: TM-T74976
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
