p38 MAPK
p38 MAPKs are a subgroup of MAPKs that respond to stress signals and are involved in the regulation of inflammation, cell differentiation, apoptosis, and autophagy. p38 MAPK signaling is crucial in immune responses and is implicated in various diseases, including chronic inflammatory conditions, cancer, and neurodegenerative disorders. At CymitQuimica, we provide a comprehensive range of p38 MAPK inhibitors and modulators to support your research in inflammation, stress response, and therapeutic development.
Found 129 products for "p38 MAPK".
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Gypenoside L
CAS:Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release.Formula:C42H72O14Purity:99.42% - 99.65%Color and Shape:SolidMolecular weight:801.0127Acumapimod
CAS:Acumapimod (BCT-197) is an orally active inhibitor of p38α MAPK (IC50 <1 μM).Formula:C22H19N5O2Purity:99.64% - ≥95%Color and Shape:SolidMolecular weight:385.4186Afatinib Dimaleate
CAS:Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.Formula:C32H33ClFN5O11Purity:98.11% - 99.87%Color and Shape:White SolidMolecular weight:718.083Rotundic acid
CAS:Rotundic acid fights various cancers: HepG2, A375, NCI-H446, MCF-7, and HT-29.Formula:C30H48O5Purity:96.91% - 99.97%Color and Shape:White SolidMolecular weight:488.6991Neflamapimod
CAS:Neflamapimod (VX-745) , a specific and effective inhibitor of p38α(IC50=10 nM), is 22-fold greater specificity against p38β and no inhibition activity to p38γ.Formula:C19H9Cl2F2N3OSPurity:97.88% - 99.75%Color and Shape:Yellow SolidMolecular weight:436.26Skatole
CAS:Skatole (3-Methyl-1H-indole), produced by bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.Formula:C9H9NPurity:99.74% - 99.96%Color and Shape:White SolidMolecular weight:131.1745Esculin
CAS:Esculin (Aesculin) is a glucoside found in horse chestnuts.Formula:C15H16O9Purity:97.93% - 99.83%Color and Shape:White SolidMolecular weight:340.2821Sertaconazole
CAS:Sertaconazole is a broad-spectrum antifungal.Formula:C20H15Cl3N2OSPurity:99.48%Color and Shape:White SolidMolecular weight:437.77Cornuside
CAS:Cornuside boosts immunity, reduces inflammation, protects heart and liver, and guards against brain injury by modulating stress responses.Formula:C24H30O14Purity:99.86% - >99.99%Color and Shape:SolidMolecular weight:542.4866SB 239063
CAS:SB 239063 (SB239063) is a potent and selective p38 MAPKα/β inhibitor with IC50 of 44 nM, showing no activity against the γ- and δ-kinase isoforms.Formula:C20H21FN4O2Purity:99.73% - 99.90%Color and Shape:SolidMolecular weight:368.4Paris saponin VII
CAS:Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.Formula:C51H82O21Purity:99.57% - 99.63%Color and Shape:SolidMolecular weight:1031.1842Ralimetinib dimesylate
CAS:Ralimetinib dimesylate (LY2228820 dimesylate) is a orally available, p38 MAPK inhibitor with potential anti-inflammatory and antineoplastic activities.Formula:C26H37FN6O6S2Purity:98% - 99.82%Color and Shape:White SolidMolecular weight:612.737R1487
CAS:R1487 is an orally bioavailable and highly selective p38α mitogen-activated protein kinase inhibitor.Formula:C19H18F2N4O3Purity:99.77%Color and Shape:SolidMolecular weight:388.368BMS582949
CAS:BMS-582949 inhibits p38 MAPK with 13 nM IC50, blocking kinase activity and activation.Formula:C22H26N6O2Purity:98.11%Color and Shape:SolidMolecular weight:406.4808Nitidine chloride
CAS:1.Formula:C21H18ClNO4Purity:96.59% - 99.55%Color and Shape:SolidMolecular weight:383.825Pexmetinib
CAS:Pexmetinib (ARRY-614) is an orally bioavailable dual p38 MAPK/Tie-2 inhibitor.Cost-effective and quality-assured.Formula:C31H33FN6O3Purity:99.07% - 99.66%Color and Shape:SolidMolecular weight:556.6305SR-318
CAS:SR-318 inhibits TNF-α (IC50=283 nM), selectively targets p38 MAPK: IC50 of 5nM (p38α), 32nM (p38β), 6.11μM (p38α/β).Formula:C27H33N5O2Purity:99.74%Color and Shape:SolidMolecular weight:459.5832SKF-86002
CAS:SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).Formula:C16H12FN3SPurity:98% - 99.85%Color and Shape:SolidMolecular weight:297.35UM-164
CAS:UM-164 (DAS-DFGO-II), a highly potent c-Src inhibitor with a dissociation constant (Kd) of 2.7 nM, also effectively inhibits p38α and p38β.Formula:C30H31F3N8O3SPurity:98.72% - 99.52%Color and Shape:SolidMolecular weight:640.679PD 169316
CAS:PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor.Formula:C20H13FN4O2Purity:98.65%Color and Shape:Yellow SolidMolecular weight:360.34
