p38 MAPK
p38 MAPKs are a subgroup of MAPKs that respond to stress signals and are involved in the regulation of inflammation, cell differentiation, apoptosis, and autophagy. p38 MAPK signaling is crucial in immune responses and is implicated in various diseases, including chronic inflammatory conditions, cancer, and neurodegenerative disorders. At CymitQuimica, we provide a comprehensive range of p38 MAPK inhibitors and modulators to support your research in inflammation, stress response, and therapeutic development.
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Esculin sesquihydrate
CAS:66778-17-4
Esculin sesquihydrate, a coumarin glucoside with fluorescent properties and a constituent of ash bark, improves …
Formula:
C15H16O9H2O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
367.31
Ref: TM-T80631
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
Talmapimod hydrochloride
CAS:309915-12-6
Talmapimod hydrochloride: selective p38α inhibitor, 9 nM IC50, 10x less effective on p38β, >2000-fold selective …
Formula:
C27H31Cl2FN4O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
549.47
Ref: TM-T12871L
| 25mg | 1,432.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
OVA-E1 peptide TFA
CAS:1262750-80-0
OVA-E1 peptide TFA activates the p38 and JNK cascades similarly in mutant and wild-type thymocytes.
Formula:
C49H77F3N10O16
Purity:
98%
Color and Shape:
Solid
Molecular weight:
1119.19
Ref: TM-T38665
| 1mg | 151.00 € | ||
| 5mg | 413.00 € | ||
| 10mg | 619.00 € | ||
| 25mg | 1,112.00 € | ||
| 50mg | 1,669.00 € | ||
| 100mg | 2,503.00 € | ||
| 200mg | 3,754.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Lucidenic acid D
CAS:98665-16-8
Lucidenic acid D2 is a nartural product from G. lucidum AF.
Formula:
C29H38O8
Purity:
98%
Color and Shape:
Solid
Molecular weight:
514.61
Ref: TM-TN1882
| 5mg | 901.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
AMG-548 dihydrochloride (864249-60-5 free base)
AMG-548 dihydrochloride: oral p38α inhibitor, Ki: 0.5 nM; less so for p38β, Ki: 36 nM; …
Formula:
C29H29Cl2N5O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
534.48
Ref: TM-T10298L2
| 1mg | 163.00 € | ||
| 5mg | 468.00 € | ||
| 10mg | 775.00 € | ||
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
AMG-548 hydrochloride (864249-60-5 free base)
AMG-548 hydrochloride is an orally active and selective p38α inhibitor (Ki: 0.5 nM) and shows …
Formula:
C29H28ClN5O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
498.02
Ref: TM-T10298
| 100mg | To inquire | ||
| 500mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
Akt/NF-κB/MAPK-IN-1
Akt/NF-κB/MAPK-IN-1 (compound 2m) serves as a potent, orally active inhibitor targeting NO with an IC50 …
Formula:
C38H56N2O4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
604.86
Ref: TM-T78838
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
SSK1
CAS:2629250-69-5
SSK1 is a senescent cell-killing and β-galactosidase-targeting precursor compound that activates phosphorylation levels of p38 …
Formula:
C31H34F2N4O18
Purity:
98.97% - 99.83%
Color and Shape:
Solid
Molecular weight:
788.61
Ref: TM-T37450
| 1mg | 199.00 € | ||
| 5mg | 497.00 € | ||
| 10mg | 717.00 € | ||
| 25mg | 1,100.00 € | ||
| 50mg | 1,470.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
R1487 Hydrochloride
CAS:449808-64-4
R1487 Hydrochloride (R1487 (Hydrochloride)) is an orally bioavailable and highly selective inhibitors of p38α.
Formula:
C19H19ClF2N4O3
Purity:
99.42%
Color and Shape:
Solid
Molecular weight:
424.83
Ref: TM-T7162
| 2mg | 71.00 € | ||
| 5mg | 104.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SB 203580 hydrochloride
CAS:869185-85-3
SB 203580 hydrochloride (Adezmapimod hydrochloride) is a p38 MAPK inhibitor that induces mitochondrial autophagy and …
Formula:
C21H17ClFN3OS
Color and Shape:
Solid
Molecular weight:
413.9
Ref: TM-T21675
| 5mg | 43.00 € | ||
| 10mg | 59.00 € | ||
| 25mg | 91.00 € | ||
| 50mg | 118.00 € | ||
| 100mg | 167.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Skepinone-L
CAS:1221485-83-1
Skepinone-L (CBS3830) is a selective p38 mitogen-activated protein kinase inhibitor.
Formula:
C24H21F2NO4
Purity:
100% - 99.76%
Color and Shape:
Solid
Molecular weight:
425.42
Ref: TM-T6130
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 204.00 € | ||
| 50mg | 307.00 € | ||
| 100mg | 454.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SKF-86002
CAS:72873-74-6
SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 …
Formula:
C16H12FN3S
Purity:
98% - 99.68%
Color and Shape:
Solid
Molecular weight:
297.35
Ref: TM-T2367
| 5mg | 49.00 € | ||
| 10mg | 82.00 € | ||
| 25mg | 136.00 € | ||
| 50mg | 194.00 € | ||
| 100mg | 287.00 € | ||
| 200mg | 406.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SB 242235
CAS:193746-75-7
SB 242235 is a potent and selective p38 MAP kinase inhibitor that may be an …
Formula:
C19H20FN5O
Purity:
99.13% - 99.68%
Color and Shape:
Solid
Molecular weight:
353.39
Ref: TM-T4078
| 2mg | 47.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 114.00 € | ||
| 25mg | 232.00 € | ||
| 50mg | 353.00 € | ||
| 100mg | 531.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Rhoifolin
CAS:17306-46-6
Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.
Formula:
C27H30O14
Purity:
98.11% - 98.87%
Color and Shape:
Solid
Molecular weight:
578.52
Ref: TM-T2755
| 20mg | 116.00 € | ||
| 1mL*10mM (DMSO) | 98.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
TAK-715
CAS:303162-79-0
TAK-715 is a p38 MAPK inhibitor for p38α.
Formula:
C24H21N3OS
Purity:
99.69%
Color and Shape:
Solid
Molecular weight:
399.51
Ref: TM-T6150
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 85.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 317.00 € | ||
| 100mg | 497.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PD 169316
CAS:152121-53-4
PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor.
Formula:
C20H13FN4O2
Purity:
98.65%
Color and Shape:
Solid
Molecular weight:
360.34
Ref: TM-T2432
| 5mg | 57.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 135.00 € | ||
| 50mg | 217.00 € | ||
| 100mg | 376.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
AMG-47a
CAS:882663-88-9
AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.
Formula:
C29H28F3N5O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
535.56
Ref: TM-T7123
| 1mg | 45.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 149.00 € | ||
| 25mg | 244.00 € | ||
| 50mg | 362.00 € | ||
| 100mg | 532.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Acumapimod
CAS:836683-15-9
Acumapimod (BCT-197) is an orally active inhibitor of p38α MAPK (IC50 <1 μM).
Formula:
C22H19N5O2
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
385.42
Ref: TM-T7367
| 1mg | 35.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 157.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 422.00 € | ||
| 1mL*10mM (DMSO) | 78.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Cornuside
CAS:131189-57-6
Cornuside boosts immunity, reduces inflammation, protects heart and liver, and guards against brain injury by …
Formula:
C24H30O14
Purity:
100% - 99.57%
Color and Shape:
Solid
Molecular weight:
542.49
Ref: TM-T4S2326
| 1mg | 94.00 € | ||
| 5mg | 259.00 € | ||
| 10mg | 409.00 € | ||
| 25mg | 662.00 € | ||
| 50mg | 915.00 € | ||
| 100mg | 1,230.00 € | ||
| 500mg | 2,471.00 € | ||
| 1mL*10mM (DMSO) | 334.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Neflamapimod
CAS:209410-46-8
Neflamapimod (VX-745) , a specific and effective inhibitor of p38α(IC50=10 nM), is 22-fold greater specificity …
Formula:
C19H9Cl2F2N3OS
Purity:
99.02% - ≥95%
Color and Shape:
Solid
Molecular weight:
436.26
Ref: TM-T6089
| 5mg | 50.00 € | ||
| 10mg | 75.00 € | ||
| 25mg | 123.00 € | ||
| 50mg | 202.00 € | ||
| 100mg | 300.00 € | ||
| 200mg | 448.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
