Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(100 products)
- Adiponectin receptor(5 products)
- CFTR(66 products)
- CGRP Receptor(54 products)
- Calcium Channel(545 products)
- Chloride channel(53 products)
- GABA Receptor(369 products)
- Monoamine Transporter(30 products)
- Monocarboxylate transporter(18 products)
- NKCC(2 products)
- NPC1L1(3 products)
- Na-K-Cl cotransporter(10 products)
- OAT(32 products)
- OCT(7 products)
- P-gp(55 products)
- Potassium Channel(283 products)
- Proton pump(41 products)
- SGLT(31 products)
- Sodium Channel(219 products)
- TRP/TRPV Channel(96 products)
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Found 2586 products of "Membrane Transporter/Ion Channel"
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URAT1 inhibitor 2
URAT1 inhibitor 2: oral URAT1/CYP blocker, IC50 of 1.36μM (URAT1), 16.97μM (CYP1A2), 5.22μM (CYP2C9); potential gout treatment.Formula:C21H18BrN3O2SColor and Shape:SolidMolecular weight:456.36Insecticidal agent 21
CAS:Insecticidal agent 21 (Compound 6) is an insecticide targeting Culex pipiens larvae with an LC50 of 0.4 μg/mL. It achieves multi-target neurotoxicity by inhibiting acetylcholinesterase (AChE) and simultaneously targeting other neural receptors, including nicotinic acetylcholine receptors (nAChR), voltage-gated sodium channels (VGSC), and γ-aminobutyric acid receptors (GABAAR). Insecticidal agent 21 shows potent insecticidal activity and can be utilized in the development of new insecticides to combat mosquito resistance to conventional agents.Formula:C37H40ClN3O2Color and Shape:SolidMolecular weight:594.185ATPase-IN-5
CAS:ATPase-IN-5 (Compound 11) is an antifungal Pma1p (H+ -ATPase) inhibitor (IC50 = 12.7 μM) that inhibits the growth of Candida albicans and Saccharomyces cerevisiae.
Formula:C10H10N4O3SPurity:99.19%Color and Shape:SolidMolecular weight:266.28Ref: TM-T204943
1mg185.00€5mg459.00€10mg657.00€25mg1,026.00€50mg1,415.00€100mg1,872.00€200mg2,555.00€PDE1-IN-4
PDE1-IN-4: inhibits PDE1C/A/B with IC50s 10/145/354 nM, may help study idiopathic pulmonary fibrosis.Formula:C33H33N3O4Color and Shape:SolidMolecular weight:535.63P2X receptor-1
P2X receptor-1 is a potential inhibitor of P2X receptor for the treatment of pain and inflammation.Formula:C14H14ClN3O3S2Color and Shape:SolidMolecular weight:371.865-O-Desmethyl donepezil
CAS:5-O-Desmethyl donepezil is a metabolite of Donepezil that acts as an inhibitor of hERG channels, with an IC50 of 1.5 μM.Formula:C23H27NO3Color and Shape:SolidMolecular weight:365.465ICA-105665
CAS:ICA-105665 is an orally active Kv7.2/7.3/7.5 channel opener, CNS-penetrant with antiseizure effects, and low hepatocyte cytotoxicity.Formula:C19H15F2N3O2Purity:98%Color and Shape:SolidMolecular weight:355.34GNE-616
CAS:GNE-616: a potent, stable, oral Nav1.7 inhibitor; Ki: 0.79 nM, Kd: 0.38 nM; for chronic pain.Formula:C24H23F4N5O3SPurity:98%Color and Shape:SolidMolecular weight:537.53(RS)-AMPA hydrobromide
CAS:AMPAR agonistFormula:C7H11BrN2O4Purity:98%Color and Shape:SolidMolecular weight:267.08KV1.3-IN-2
CAS:KV1.3-IN-2 (Compound I) selectively inhibits the kv1.3 potassium channel without affecting the hERG channel. It is applicable in research related to immune-associated diseases such as psoriasis, rheumatoid arthritis, and systemic lupus erythematosus.
Formula:C16H23ClN2O4Color and Shape:SolidMolecular weight:342.818Opakalim
CAS:Opakalim is an activator of potassium channels (potassium channel) and exhibits anticonvulsant activity.Formula:C18H22F2N4OColor and Shape:SolidMolecular weight:348.39WS-898
WS-898 boosts paclitaxel efficacy in resistant cells by inhibiting ABCB1; IC50: SW620/Ad300 - 5.0 nM, KB-C2 - 3.67 nM, HEK293/ABCB1 - 3.68 nM.Formula:C33H25N7OSColor and Shape:SolidMolecular weight:567.66Blixeprodil
CAS:Blixeprodil (GM-1020) is an orally active NMDA receptor antagonist with an affinity of Ki = 3.25 µM in rat cortical tissue. It inhibits NR1/2A-NMDAR-mediated currents in HEK293 cells with an IC50 of 1.192 µM. Blixeprodil demonstrates antidepressant effects in rat models and exhibits blood-brain barrier permeability.Formula:C13H16FNOColor and Shape:SolidMolecular weight:221.271IAA65
CAS:IAA65 is a potent inhibitor of T-type calcium channels, exhibiting an IC50 value of 18.9 μM, and holds potential for use in epilepsy research [1].Formula:C16H13F6NO2Color and Shape:SolidMolecular weight:365.27VU0463271 quarterhydrate
VU0463271 quarterhydrate is a potent KCC2 antagonist, with an IC 50 of 61 nM [1].Formula:C19H20N4O2S2Color and Shape:SolidMolecular weight:387V-ATPase-IN-1
CAS:V-ATPase-IN-1 (Compound 3b-03) is an inhibitor of Vacuolar-type H+-ATPases (V-ATPase), exhibiting an inhibition constant (IC50) of 194.80 μM and effectively targeting the V-ATPase subunit A with a dissociation constant (Kd) of 0.803 μM. This compound demonstrates insecticidal activity against M. separata (LC50 = 2.64 mM), aiding in the development of chemical insecticides.Formula:C21H20ClNO2Color and Shape:SolidMolecular weight:353.84(S)-Albuterol
CAS:(S)-Albuterol functions as a muscarinic receptor and phospholipase C activator, enhancing the intracellular free calcium concentration in airway smooth muscle cells.Formula:C13H21NO3Color and Shape:SolidMolecular weight:239.311(R)-(+)-Pantoprazole sodium
CAS:(R)-(+)-Pantoprazole ((R)-(+)-BY1023) sodium is a proton pump inhibitor used in the study of esophageal erosion and ulcers.Formula:C16H15F2N3NaO4SColor and Shape:SolidMolecular weight:406.36(3R,6S)-Bassiatin
CAS:(3R,6S)-Bassiatin represents the enantiomeric form of the fungal metabolite known as bassiatin.Formula:C15H19NO3Color and Shape:SolidMolecular weight:261.32Nav1.7 blocker 1
CAS:Nav1.7 blocker 1 (example 41), an effective Na+ channel (Na v) blocker, exhibits a potent IC50 value of 0.037 μM. This compound is utilized in pain research, encompassing neuropathic, postoperative, and inflammatory pain among others [1].Formula:C22H21FN4O4Molecular weight:424.42DL-AP5 lithium
CAS:DL-AP5 (2-APV) lithium is a competitive antagonist of the NMDA (N-Methyl-D-aspartate) receptor. It exhibits notable analgesic activity and specifically blocks channels in the rabbit retina.Formula:C5H11LiNO5PColor and Shape:SolidMolecular weight:203.063-Methoxy PCE hydrochloride
CAS:3-Methoxy PCE (3-MEO PCE) hydrochloride is an arylcyclohexylamine compound that functions as an NMDA receptor antagonist with a pKi value of 7.22.Formula:C15H24ClNOColor and Shape:SolidMolecular weight:269.81ABCG2-IN-4
CAS:ABCG2-IN-4 (Compound K31) is an orally active ABCG2 inhibitor that reduces the release of Protoporphyrin IX (PPIX) from red blood cells into the plasma and prevents phototoxicity. In mouse models, ABCG2-IN-4 also demonstrates anti-inflammatory and antioxidant properties.
Formula:C24H32N4O4Color and Shape:SolidMolecular weight:440.535PfCLK3-IN-1
PfCLK3-IN-1 (Compound 4) serves as a covalent inhibitor of the malaria parasite CLK3 (Pf CLK3) under alkaline conditions, with a pEC50 of 7.1. It inhibits the maturation of gametocytes during the sexual stage of the parasite, thereby hindering transmission. Additionally, PfCLK3-IN-1 effectively suppresses the Dd2-B2 clone of the malaria parasite, exhibiting an IC50 of 239.5 nM.Formula:C28H27ClN4O4Color and Shape:SolidMolecular weight:518.99Nav1.8-IN-5
CAS:Nav1.8-IN-5 (Example 1), a voltage-gated sodium channel Nav1.8 inhibitor, is applicable in the research of Nav1.8-mediated diseases including pain, pain-related disorders, and cardiovascular diseases (such as atrial fibrillation) [1].Formula:C23H15F4N3O2Color and Shape:SolidMolecular weight:441.38Lafadofensine (D-(-)-Mandelic acid)
Lafadofensine D-(-)-Mandelic acid is a monoamines reuptake inhibitor with adequate effects when administered short-term.Formula:C32H32F2N2O6Color and Shape:SolidMolecular weight:578.6Refisolone
CAS:Refisolone is an antagonist of the GABAA receptor.Formula:C18H24O3Color and Shape:SolidMolecular weight:288.381CHI3L1-IN-1
CAS:CHI3L1-IN-1 (Compound 30), a potent inhibitor of Chitinase-3-like protein 1 (CHI3L1) (YKL-40), exhibits an IC 50 of 50 nM. Additionally, this compound displays inhibitory activity against the hERG channel with an IC 50 of 2.3 μM [1].Formula:C22H27Cl2N3OMolecular weight:420.38SW016789
CAS:SW016789 is a potent high-secretion inducer targeting VDAC1, which directly stimulates insulin secretion and calcium ion influx in β cells. It transiently induces endoplasmic reticulum stress (ER stress) without causing β cell death. The response it triggers is reversible and non-apoptotic, making SW016789 useful for studying β cell dysfunction in type 2 diabetes (T2DM).Formula:C20H19N3OSColor and Shape:SolidMolecular weight:349.45AZD 2066 hydrate
AZD 2066 hydrate is a selective, orally active, and brain-penetrant antagonist of mGluR5. It exhibits antinociceptive effects [1].Formula:C19H18ClN5O3Color and Shape:SolidMolecular weight:386.33Kv3 modulator 5
CAS:Kv3 modulator 5 (Example 5), a Kv3 channel modulator, enhances the Kv3.2 current and may be employed in research of hearing disorders [1].Formula:C20H20N4O4Color and Shape:SolidMolecular weight:380.4URAT1-IN-14
CAS:URAT1-IN-14 is a potent and orally active inhibitor of uric acid transporter 1 (URAT1). It demonstrates an IC50 value of 0.72 μM for inhibiting human URAT1 in HEK293 cells and exhibits low cytotoxicity in Hep-G2 cells. URAT1-IN-14 reduces uric acid levels in a hyperuricemia mouse model and is applicable in research on hyperuricemia and gout.Formula:C19H19NO3SColor and Shape:SolidMolecular weight:341.42Calpain Inhibitor-2
CAS:Calpain Inhibitor-2: Lipophilic, moderates growth of A-375, B-16F1, PC-3 cancers, and hinders 80% DU-145 cell invasion.Formula:C26H33N3O5SColor and Shape:SolidMolecular weight:499.62ELP-004
CAS:ELP-004 is a TRPC channel inhibitor that blocks Ca2+ entry mediated by TRPC channels. It serves as an osteoclast inhibitor by preventing osteoclast differentiation. ELP-004 also hinders basal Ca2+ levels and the associated translocation of NFATc1 in inflammatory osteoclastogenesis. Additionally, it reduces bone erosion in mouse models of rheumatoid arthritis.Formula:C10H11Cl2NOMolecular weight:232.106Thiomuscimol hydrobromide
CAS:Thiomuscimol hydrobromide is an agonist of GABAA receptor.Formula:C4H6N2OSPurity:98%Color and Shape:SolidMolecular weight:130.17AqF026
CAS:AqF026 is an AQP1 agonist that enhances AQP1-mediated water transport. It is utilized in research related to peritoneal dialysis and diseases associated with local water metabolism defects, such as subretinal edema and cerebral edema.Formula:C20H19ClN2O5SColor and Shape:SolidMolecular weight:434.89URAT1 inhibitor 13
CAS:URAT1 inhibitor13 (compound 22k) is a potent inhibitor of URAT1, useful for research related to gout.Formula:C18H14Cl2N2O2Color and Shape:SolidMolecular weight:361.22β-CCM
CAS:β-CCM is a benzodiazepine receptor inverse agonist with anxiogenic and convulsant effects. It enhances emotional reactivity and reduces interference sensitivity in spatial working memory tasks. β-CCM is applicable in research related to anxiety disorders.Formula:C13H10N2O2Color and Shape:SolidMolecular weight:226.231Cav 3.1 blocker 1
CAS:Cav 3.1 blocker 1 (compound 12) is a T-type calcium channel inhibitor with an IC50 value of 160 nM for Cav3.1. It exhibits weaker inhibition on Cav 3.2 with an IC50 of 5000 nM and shows no inhibitory effect on Cav 3.3 and Cav 1.2 (IC50 > 10000 nM).Formula:C26H19F6N3O2Color and Shape:SolidMolecular weight:519.438ATPase-IN-6
CAS:ATPase-IN-6 is an inhibitor of H+/K+-ATPase (ATPase) and a derivative of imidazopyridine. It exhibits significant antiviral activity against various viruses, such as HIV-1 and SARS-CoV-2. ATPase-IN-6 is applicable in antiviral infection research.Formula:C29H25N3O4SColor and Shape:SolidMolecular weight:511.59CGS-9895
CAS:CGS-9895 is a GABA antagonist that operates by interacting with the benzodiazepine binding site on GABA receptors containing the γ subunit (ag).Formula:C17H13N3O2Color and Shape:SolidMolecular weight:291.304Odevixibat
CAS:Odevixibat (A4250) is a selective oral inhibitor for ileal bile acid transport, potentially treating primary biliary cirrhosis.Formula:C37H48N4O8S2Purity:99.53% - 99.83%Color and Shape:SolidMolecular weight:740.93SYM2206
CAS:SYM2206 is a low affinity non-competitive AMPA receptor antagonist with an IC50 value of 1.6 μM.SYM2206 exhibits anticancer activity by blocking Nav1.6-mediatedFormula:C20H22N4O3Purity:99.8%Color and Shape:SolidMolecular weight:366.41(+)-Tetrabenazine
CAS:(+)-Tetrabenazine ((3R,11bR)-Tetrabenazine) is a reversible vesicular monoamine transporter 2 (VMAT-2) inhibitor, inhibits transport by VMAT2 with 10-foldFormula:C19H27NO3Purity:98.69%Color and Shape:SolidMolecular weight:317.42Suzetrigine
CAS:Suzetrigine (VX-548) is an oral NaV1.8 inhibitor with analgesic properties for acute pain research.Formula:C21H20F5N3O4Purity:98.08% - 99.27%Color and Shape:SolidMolecular weight:473.39Ref: TM-T69552
1mg58.00€5mg114.00€10mg170.00€25mg266.00€300g129,112.00€50mg457.00€100mg747.00€200mg1,026.00€1mL*10mM (DMSO)118.00€SDZ 220-040
CAS:SDZ 220-040 是一种选择性哺乳动物 NMDA 受体拮抗剂，可诱导根系生长的部分无重力模式 。Formula:C16H16Cl2NO6PPurity:98.13%Color and Shape:SolidMolecular weight:420.18BDZ-g
CAS:BDZ-g: potent, selective AMPA receptor antagonist; useful for researching neurological disorders.Formula:C21H21N5O2SPurity:99.97%Color and Shape:SolidMolecular weight:407.49Umbellulone
CAS:Umbellulone is a natural product isolated from Umbellularia californica, and stimulates the TRPA1 channel in a subset of peptidergic, nociceptive neurons, activating the trigeminovascular system via this mechanism.Formula:C10H14OPurity:98%Color and Shape:SolidMolecular weight:150.22(-)-Bicuculline methobromide
CAS:(-)-Bicuculline methobromide is a potent antagonist of GABAA receptor .Formula:C21H20BrNO6Color and Shape:WhiteMolecular weight:462.295-Hydroxylansoprazole
CAS:5-Hydroxylansoprazole (AG1908) is the active metabolite of plasma Lansoprazole, inhibits the proton pump, and is used in the study of peptic ulcers.Formula:C16H14F3N3O3SPurity:99.00%Color and Shape:SolidMolecular weight:385.36A-887826
CAS:A-887826 is a selective, orally bioavailable, and voltage-dependent Na(v1.8) channel blocker (IC50: 11 nM). It attenuates neuropathic tactile allodynia in vivo.Formula:C26H29ClN4O3Color and Shape:SolidMolecular weight:480.99Alfadolone acetate
CAS:Alfadolone acetate is a gamma-aminobutyric acid (GABA) receptor agonist.Formula:C23H34O5Color and Shape:SolidMolecular weight:390.5122(S)-hydroxy Cholesterol
CAS:22(S)-hydroxy Cholesterol is a synthetic oxysterol and a modulator of the liver X receptor (LXR). [1] t prevents monocyte chemoattractant protein 1 (MCP-1) expression induced by the LXR agonist GW 3965 in primary hepatocytes and downregulates mRNA expression of the LXR target genes CD36, ACSL1, and SCD-1 in human myotubes. It decreases triacylglycerol and diacylglycerol synthesis from labeled palmitate and acetate, respectively, in human myoblasts by 50% when used at a concentration of 10 uM. 22(S)-hydroxy Cholesterol also reduces fatty acid synthase (FAS) reporter activity through an LXR response element in the promoter region in COS-1 cells transfected with RXRα and LXRα and decreases the expression of MCP-1 and CCR2 in a mouse model of chronic ethanol consumption.[1] [2] Dietary supplementation of 22(S)-hydroxy cholesterol (30 mg/kg per day) leads to less body weight gain and lower liver triacylglycerol levels in rats when fed either a regular chow or high-fat diet as well as prevents an increase in plasma triacylglycerol levels resulting from a high-fat diet.[3]Formula:C27H46O2Color and Shape:SolidMolecular weight:402.65PF-06761281
CAS:PF-06761281 is a partially selective sodium-coupled citrate transporter protein (NaCT/SLC13A5) inhibitor, oral, reducing plasma glucose concentration.Formula:C13H17NO6Color and Shape:SolidMolecular weight:283.282-AEMP TFA
CAS:2-AEMP TFA is a potent and rapidly acting antagonist of GABA(A)-ρ1 receptors. 2-AEMP is an analog of GABA.Formula:C3H10NO3PPurity:98%Color and Shape:SolidMolecular weight:139.091Dexivacaine
CAS:Dexivacaine is an type of anesthetic.Formula:C15H22N2OColor and Shape:SolidMolecular weight:246.352-(Trifluoromethyl)cinnamic acid
CAS:2-(Trifluoromethyl)cinnamic acid is a useful organic compound for research related to life sciences. The catalog number is T64859 and the CAS number is 2062-25-1.Formula:C10H7F3O2Color and Shape:SolidMolecular weight:216.1593-Methylglutaconic acid
CAS:3-Methylglutaconic acid, a primary metabolite accumulating in 3-Methylglutaconic aciduria (MGTA), induces lipid and protein oxidation, while diminishing non-enzymatic antioxidant defenses in cerebral cortex supernatants, thereby promoting oxidative stress in the cerebral cortex. This compound is utilized in research concerning brain damage diseases [1].Formula:C6H8O4Purity:98%Color and Shape:SolidMolecular weight:144.13Zastaprazan
CAS:Zastaprazan (JP-1366, compound 6) is a potassium-competitive acid blocker and proton pump inhibitor that suppresses gastric acid secretion, indicated for GERD.Formula:C22H26N4OPurity:99.97%Color and Shape:SolidMolecular weight:362.48(Rac)-Lanicemine
CAS:(Rac)-Lanicemine ((Rac)-AZD6765) is the racemate of Lanicemine. Lanicemine (AZD6765) is a low-trapping NMDA channel blocker with a Ki of 0.56-2.1 μM for the NMDA receptor and IC50 values of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively. Lanicemine shows antidepressant effects [1].Formula:C13H14N2Color and Shape:SolidMolecular weight:198.26L-Cysteine S-sulfate sodium salt sesquihydrate
CAS:L-Cysteine S-sulfate sodium salt sesquihydrate is a useful organic compound for research related to life sciences. The catalog number is T64782 and the CAS number is 150465-29-5.Formula:C9H25N3Na3O17S6Color and Shape:SolidMolecular weight:708.63Indoxacarb
CAS:Indoxacarb is an Oxadiazine insecticide.Formula:C22H17ClF3N3O7Purity:98%Color and Shape:SolidMolecular weight:527.83Verapamil EP Impurity C hydrochloride
CAS:NSC-609249 hydrochloride, an impurity of Verapamil, is a calcium channel blocker with potent orally active properties. It also functions as a first-generation P-glycoprotein (P-gp) inhibitor.Formula:C12H20ClNO2Color and Shape:SolidMolecular weight:245.75GNE-9278
CAS:GNE-9278 is a highly selective NMDAR orthosteric modulator that targets the GluN1 transmembrane structural domain (TMD), enhancing peak current and agonist affinity in activated NMDAR.Formula:C21H27N5O3SColor and Shape:SolidMolecular weight:429.54Filapixant
CAS:Filapixant, a purinoreceptor antagonist. This compound serves as the active reference substance for Eliapixant.Formula:C24H26F3N5O3SColor and Shape:SolidMolecular weight:521.56Apcin A HCL
CAS:Apcin A HCL is an Apcin derivative. Apcin A HCL is an anaphase-promoting complex (APC) inhibitor. Apcin-A HCL interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Apcin-A HCL can be used to synthesize the PROTAC CP5V [1].
Formula:C10H15Cl4N5O2Purity:99.30%Color and Shape:SolidMolecular weight:379.07Vonoprazan fumarate
CAS:Vonoprazan fumarate (TAK-438) is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase.
Formula:C17H16FN3O2S·C4H4O4Purity:99.16% - 99.98%Color and Shape:SolidMolecular weight:461.46CGP 44532
CAS:CGP 44532 a GABAB receptor agonist.Formula:C4H12NO3PPurity:98%Color and Shape:SolidMolecular weight:153.12Phenamil methanesulfonate
CAS:TRPP3 channel inhibitorFormula:C13H16ClN7O4SPurity:98%Color and Shape:SolidMolecular weight:401.83Fostedil
CAS:Fostedil enhances heart function, maintains blood flow during partial/total coronary occlusions, and lowers aortic pressure.Formula:C18H20NO3PSPurity:98%Color and Shape:SolidMolecular weight:361.4CMPDA
CAS:CMPDA is a positive allosteric modulator of AMPA receptors [EC50s: 45.4 nM/63.4 nM for GluA2i/GluA2o receptor].Formula:C16H28N2O4S2Purity:98%Color and Shape:SolidMolecular weight:376.53Gacyclidine
CAS:Gacyclidine (OTO311), an NMDA receptor blocker, treats tinnitus and injuries in the brain and spinal cord.Formula:C16H25NSPurity:99.85% - 99.92%Color and Shape:SolidMolecular weight:263.44Motugivatrep
CAS:Motugivatrep is a potent and selective TRPV1 antagonist that can be used to study TRPV1-related respiratory diseases.
Formula:C22H20F3NO3Purity:99.22%Color and Shape:SolidMolecular weight:403.39Ref: TM-T64312
Discontinued productAKOS-22
CAS:AKOS-22: potent VDAC1 inhibitor, Kd=15.4 μM; prevents mitochondrial dysfunction and apoptosis.Formula:C22H21ClF3N3O3Purity:98%Color and Shape:SolidMolecular weight:467.87T16A(inh)-C01
CAS:T16A(inh)-C01 is the Ca(2+)-activated Cl(-) Channel, Ano1 class C inhibitor.Formula:C18H16O5Purity:98%Color and Shape:SolidMolecular weight:312.32Pazinaclone
CAS:Pazinaclone is a non-benzodiazepine (GABAA) partial agonist with sedative and anxiolytic activity.Formula:C25H23ClN4O4Purity:97.79% - 98.65%Color and Shape:SolidMolecular weight:478.93Tifenazoxide
CAS:Tifenazoxide is an effective and SUR1/Kir6.2 selective KATP channels opener. Tifenazoxide has an anti-diabetic effect, can inhibit glucose-stimulated insulin release in vitro and in vivo.Formula:C9H10ClN3O2S2Purity:98%Color and Shape:SolidMolecular weight:291.78Pipequaline
CAS:Pipequaline (PK-8165) is an anticonflict & anticonvulsant quinoline derivative. It is an anxiolytic drug that was never marketed. It possesses a novel chemical structure that is not closely related to other drugs of this type. The drug has a similar pharmacological profile to the benzodiazepine family of drugs, but with mainly anxiolytic properties and very little sedative, amnestic or anticonvulsant effects, and so is classified as a nonbenzodiazepine anxiolytic.Formula:C22H24N2Purity:98%Color and Shape:SolidMolecular weight:316.44Ref: TM-T4655
Discontinued productXilmenolone
CAS:Xilmenolone acts as a positive allosteric modulator of the GABA_A receptor [1].
Formula:C26H37N3O2Purity:98%Color and Shape:SolidMolecular weight:423.59Belfosdil
CAS:Belfosdil is a blocker of antihypertensive calcium channel.Formula:C27H50O7P2Purity:98%Color and Shape:SolidMolecular weight:548.63CGP 56999A
CAS:CGP 56999A is a GABA(B) receptor antagonist; it boosts BDNF and reduces dopamine loss in rat striatum.Formula:C19H30NO5PPurity:98%Color and Shape:SolidMolecular weight:383.42Bumetanide sodium
CAS:Bumetanide sodium, a potent diuretic, blocks NKCC1 (IC50: 0.68 μM) and NKCC2 (IC50: 4.0 μM).Formula:C17H19N2NaO5SColor and Shape:SolidMolecular weight:386.4LFS-1107
CAS:LFS-1107, a reversible CRM1 inhibitor (Kd: 12.5 pM), selectively targets and eliminates ENKTL cells, offering potential for cancer research applications [1].
Formula:C12H11N5OS2Purity:98%Color and Shape:SolidMolecular weight:305.38UBP310
CAS:UBP310 (UBP 310) is a GLUK5 kainate receptor antagonistFormula:C14H15N3O6SPurity:98%Color and Shape:SolidMolecular weight:353.35HMR 1556
CAS:HMR 1556 is a chromanol derivative and is an IKs blocker (IC50s of 10.5 nM and 34 nM in canine and guinea pig left ventricular myocytes, respectively).Formula:C17H24F3NO5SColor and Shape:SolidMolecular weight:411.44VMAT2-IN-2 tosylate
CAS:VMAT2-IN-2 tosylate is a potent inhibitor of VMAT2 and is applicable in the research of tardive dyskinesia [1].
Formula:C27H36F3NO6SPurity:98%Color and Shape:SolidMolecular weight:559.64
