CymitQuimica logo
Membrane Transporter/Ion Channel

Membrane Transporter/Ion Channel

Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.

Subcategories of "Membrane Transporter/Ion Channel"

Show 13 more subcategories

Found 2293 products of "Membrane Transporter/Ion Channel"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • PHP 501 trifluoroacetate
    Targetmol
    + Info

    PHP 501 trifluoroacetate

    CAS:
    <p>GABAA antagonist</p>
    Formula:C20H21N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:319.4

    Ref: TM-T23152

  • ML-252 hydrochloride
    Targetmol
    + Info

    ML-252 hydrochloride

    CAS:
    <p>ML-252 is a potent, selective inhibitor of the Kv7.2 voltage-gated potassium channel, demonstrating an IC50 value of 69 nM in patch clamp assays. It exists as the (S)-enantiomer, which is significantly more effective than both its (R)-enantiomer counterpart and the racemic mixture, with respective IC50 values of 944 nM and 160 nM. ML-252 exhibits high selectivity for Kv7.2 over other potassium channel subtypes and shows minimal activity against more than 68 G protein-coupled receptors, various transporters, L- and N-type calcium channels, K_ATP, and hERG potassium channels. However, it does inhibit the melatonin MT1 receptor by 61% at a 10 µM concentration.</p>
    Formula:C20H24N2OHCl
    Color and Shape:Solid
    Molecular weight:344.9

    Ref: TM-T85299

  • JYL-273
    Targetmol
    + Info

    JYL-273

    CAS:
    JYL-273 is a TRPV1 agonist.
    Formula:C28H39NO4S
    Color and Shape:Solid
    Molecular weight:485.68

    Ref: TM-T24236

  • Kv3 modulator 3
    Targetmol
    + Info

    Kv3 modulator 3

    CAS:
    <p>Kv3 modulator 3 is a selective modulator of Kv3.1 and/or Kv3.2 and/or Kv3.3 channels .has analgesic activity for use in the prophylaxis o or treatment of pain.</p>
    Formula:C19H18N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:350.37

    Ref: TM-T11789

  • CGP36216 hydrochloride
    Targetmol
    + Info

    CGP36216 hydrochloride

    CAS:
    <p>CGP36216 hydrochloride acts as a selective antagonist at the presynaptic GABA receptor, specifically binding to the GABAB receptor with a Ki value of 0.3 μM. This compound is leveraged in research focused on anxiety and trauma-related disorders [1] [2].</p>
    Formula:C5H15ClNO2P
    Color and Shape:Solid
    Molecular weight:187.6

    Ref: TM-T84878

  • Licostinel
    Targetmol
    + Info

    Licostinel

    CAS:
    <p>Licostinel (CGP 63446) is a glutamate receptor antagonist. Licostinel protects against permanent focal cerebral ischemia.</p>
    Formula:C8H3Cl2N3O4
    Purity:98.02%
    Color and Shape:Solid
    Molecular weight:276.03

    Ref: TM-T27828

  • (R)-Vanzacaftor
    Targetmol
    + Info

    (R)-Vanzacaftor

    CAS:
    <p>(R)-Vanzacaftor ((R)-VX-121) is a cystic fibrosis transmembrane conductance regulator (CFTR) modulator [1].</p>
    Formula:C32H39N7O4S
    Color and Shape:Solid
    Molecular weight:617.76

    Ref: TM-T84699

  • JT010
    Targetmol
    + Info

    JT010

    CAS:
    <p>JT010 is an effective agonist of TRPA1 (EC50 = 0.65 nM).</p>
    Formula:C16H19ClN2O3S
    Purity:99.75%
    Color and Shape:Solid
    Molecular weight:354.85

    Ref: TM-T15628

  • LOE 908 hydrochloride
    Targetmol
    + Info

    LOE 908 hydrochloride

    CAS:
    <p>Broad spectrum cation channel blocker</p>
    Formula:C41H49ClN2O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:749.29

    Ref: TM-T22929

  • Oct4 inducer-2
    Targetmol
    + Info

    Oct4 inducer-2

    CAS:
    <p>Oct4 Inducer-2, an OCT4 inducer, sustains hiPSC formation by enhancing endogenous OCT4 expression and has applications in anti-aging research [1].</p>
    Formula:C14H16N2O2S
    Color and Shape:Solid
    Molecular weight:276.35

    Ref: TM-T79208

  • P2X3 antagonist 34
    Targetmol
    + Info

    P2X3 antagonist 34

    CAS:
    Potent P2X3 antagonist 34, oral, selective for human, rat, guinea pig receptors; IC50s: 25/92/126 nM; strong anti-tussive, no taste change.
    Formula:C24H26F2N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:456.48

    Ref: TM-T10560

  • PZ-II-029
    Targetmol
    + Info

    PZ-II-029

    CAS:
    <p>PZ-II-029 is a modulator of α6β3γ2-selective GABAA channel.</p>
    Formula:C18H15N3O3
    Purity:99.79%
    Color and Shape:Solid
    Molecular weight:321.33

    Ref: TM-T28479

  • A-1165442
    Targetmol
    + Info

    A-1165442

    CAS:
    <p>A-1165442 is a competitive TRPV1 antagonist. For human TRPV, the IC50 values is 9 nM.</p>
    Formula:C22H20ClF2N3O2
    Color and Shape:Solid
    Molecular weight:431.86

    Ref: TM-T14067

  • NaPi2b-IN-2
    Targetmol
    + Info

    NaPi2b-IN-2

    CAS:
    <p>NaPi2b-IN-2 (compound 5) serves as a potent inhibitor of the sodium-dependent transport protein 2b (SLC34A2, NaPi2b), exhibiting an IC50 of 38 nM against human</p>
    Formula:C41H47ClF3N5O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:814.36

    Ref: TM-T78146

  • Risevistinel
    Targetmol
    + Info

    Risevistinel

    CAS:
    <p>Risevistinel (NYX-783), a positive allosteric modulator of the N-methyl-D-aspartate (NMDA) receptor, may mitigate cognitive deficits in neurodegenerative</p>
    Formula:C14H23N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:297.35

    Ref: TM-T79857

  • Dimethylamiloride
    Targetmol
    + Info

    Dimethylamiloride

    CAS:
    <p>Dimethylamiloride is a specific inhibitor of antiporters [1].</p>
    Formula:C8H12ClN7O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:257.68

    Ref: TM-T78139

  • PF-05105679
    Targetmol
    + Info

    PF-05105679

    CAS:
    <p>PF-05105679 is a selective TRPM8 antagonist (IC50 = 103 nM). PF-05105679 can be used in research on cold-related pain.</p>
    Formula:C26H21FN2O3
    Purity:99.84%
    Color and Shape:Solid
    Molecular weight:428.45

    Ref: TM-T16483

  • NO-711ME
    Targetmol
    + Info

    NO-711ME

    CAS:
    <p>NO-711ME (N-O711 Methyl ester) is a prodrug of NO-711. It also is a potent and selective GABA uptake inhibitor.</p>
    Formula:C22H24N2O3
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:364.44

    Ref: TM-T24540

  • mGAT-IN-1
    Targetmol
    + Info

    mGAT-IN-1

    CAS:
    <p>mGAT-IN-1 is a potent, non-selective GAT inhibitor that inhibits mGAT3 activity well (IC50: 2.5 μM, pIC50: 5.61).</p>
    Formula:C28H34ClN3O2S2
    Color and Shape:Solid
    Molecular weight:544.17

    Ref: TM-T63832

  • 8-Pcpt-cGMP
    Targetmol
    + Info

    8-Pcpt-cGMP

    CAS:
    <p>8-Pcpt-cGMP acts as an agonist for cyclic nucleotide-gated (CNG) channels with an EC50 of 0.5 μM and exhibits good membrane permeability. This compound is utilized in research to explore the role of CNG channels in visual and olfactory signal transduction.</p>
    Formula:C16H15ClN5O7PS
    Color and Shape:Solid
    Molecular weight:487.81

    Ref: TM-T88702