Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(93 products)
- Adiponectin receptor(5 products)
- CFTR(64 products)
- CGRP Receptor(51 products)
- Calcium Channel(494 products)
- Chloride channel(49 products)
- GABA Receptor(336 products)
- Monoamine Transporter(23 products)
- Monocarboxylate transporter(17 products)
- NKCC(2 products)
- NPC1L1(3 products)
- Na-K-Cl cotransporter(8 products)
- OAT(27 products)
- OCT(7 products)
- P-gp(53 products)
- Potassium Channel(276 products)
- Proton pump(39 products)
- SGLT(30 products)
- Sodium Channel(202 products)
- TRP/TRPV Channel(93 products)
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Found 2280 products of "Membrane Transporter/Ion Channel"
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Iberiotoxin
CAS:<p>Selective blocker of the big conductance Ca2+-activated K+ channel.</p>Formula:C179H274N50O55S7Purity:98%Color and Shape:SolidMolecular weight:4230TRPM8 antagonist 3
CAS:<p>TRPM8 antagonist 3 is a blocker of TRPM8 (IC50 = 11 nM).</p>Formula:C13H12N2O4SPurity:99.74%Color and Shape:SolidMolecular weight:292.31TRPV1 activator-1
CAS:<p>TRPV1 Activator-1 (Compound 8), a capsaicin analog featuring a modified neck structure, specifically interacts with the T551 residue [1].</p>Formula:C18H27NO2SColor and Shape:SolidMolecular weight:321.48PF-06456384 trihydrochloride
CAS:<p>PF-06456384 trihydrochloride is a selective NaV1.7 inhibitor acting through protein-ligand binding. intravenous infusion and pain research.</p>Formula:C35H35Cl3F3N7O3S2Purity:99.16%Color and Shape:SolidMolecular weight:829.18MASP-2-IN-1
<p>MASP-2-IN-1 (Compound 77) is an inhibitor of mannan-binding lectin-associated serine proteases (MASP), specifically targeting MASP2 and MASP3, with IC50 values of 11.4 nM and 13.2 µM, respectively. It shows weak inhibitory activity on hERG with an IC50 of 175 µM. This compound exhibits poor stability in mouse plasma, with a half-life of 4.4 hours.</p>Formula:C22H21N7O3SColor and Shape:SolidMolecular weight:463.512GS-9191 PM
<p>GS-9191 PM: novel antitumorviral bis-amide prodrug, inhibits MDR1/BCRP, has antiproliferative activity.</p>Formula:C11H16N6OPurity:99.79%Color and Shape:SoildMolecular weight:248.28BDBM50597431
CAS:<p>BDBM50597431 is an NMDA receptor modulator that may have can be used to study Alzheimer's disease and Parkinson's syndrome.</p>Formula:C27H43F3O2Purity:98.64% - 99.28%Color and Shape:SoildMolecular weight:456.62GluN2A Allosteric modulator 1
<p>GluN2A Allosteric modulator 1 (Compound 11) is an orally bioavailable compound that effectively crosses the blood-brain barrier and functions as a highly selective negative allosteric modulator of GluN2A. It exhibits an IC50 of 0.042 μM for GluN2A and 13 μM for GluN2B. This compound is useful for research in neurological disorders.</p>Formula:C20H16ClF2N5O2Color and Shape:SolidMolecular weight:431.823Huwentoxin I
CAS:<p>Huwentoxin I (HWTX-I) is a peptide toxin that targets and inhibits both voltage-gated sodium channels and N-type calcium channels.</p>Formula:C161H246N48O44S6Purity:98%Color and Shape:SolidMolecular weight:3750.36Mambalgin 1
CAS:<p>ASIC1a inhibitor; IC50: 192 nM (human), 72 nM (dimer); inactive channel binding; selective; pain response delay.</p>Formula:C272H429N85O84S10Purity:98%Color and Shape:SolidMolecular weight:6554.51BKCa activator-1
<p>BKCa activator-1 (Compound 51b) is an orally active activator of BKCa calcium-activated potassium channels with an EC50 of 2.82 μM. It promotes K+ efflux, leading to cell membrane hyperpolarization and inhibition of smooth muscle contraction. In a spontaneous hypertensive rat (SHR) model, it alleviates urinary incontinence and exhibits antitussive effects in a guinea pig cough model.</p>Formula:C22H23F7N2O3Color and Shape:SolidMolecular weight:496.418Atagabalin
CAS:<p>Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.</p>Formula:C10H19NO2Color and Shape:SolidMolecular weight:185.26Ebio2
<p>Ebio2 is an effective activator of KCNQ2.</p>Formula:C17H19F2N3O2Color and Shape:SolidMolecular weight:335.349Ethacrynic acid D5
CAS:<p>Ethacrynic acid: a diuretic, anti-inflammatory, inhibits calcium channels, GSTs, NF-kB pathway, and modulates leukotriene; has deuterium-labeled form.</p>Formula:C13H12Cl2O4Purity:98%Color and Shape:SolidMolecular weight:308.17GABAA receptor modulator-3
<p>GABAA receptor modulator-3 (compound 3b) is a positive allosteric modulator (PAM). It inhibits the peak current and steady-state current of α1β3γ2 GABAAR with IC50 values of 671 μM and 64 μM, respectively.</p>Formula:C18H22O2Color and Shape:SolidMolecular weight:270.37GaTx2
CAS:<p>High-affinity ClC-2 blocker (KD ~50 pM), selective over other ClCs/CFTR/GABAC/CaCC/KV1.2; slows activation, no effect on open channels.</p>Formula:C125H199N39O47S6Purity:98%Color and Shape:SolidMolecular weight:3192.54AQP4 (201-220)
CAS:<p>AQP4 (201-220) is the encephalitogenic epitope of AQP-4. AQP4 (201-220) can induce experimental autoimmune encephalomyelitis (EAE), characterized by midline brain lesions, retinal lesions, and lesions at the gray matter/white matter boundary of the spinal cord. AQP-4 is the target antigen in neuromyelitis optica.</p>Formula:C97H143N27O27SColor and Shape:SolidMolecular weight:2151.4Cavα2δ-IN-1
CAS:<p>Cavα2δ-IN-1 demonstrates exceptional specificity for voltage-gated calcium channels Cavα2δ-1 (with a Ki value of 6 nM), in comparison to Cavα2δ-2 (with a Ki</p>Formula:C18H27N5OColor and Shape:SolidMolecular weight:329.448GX 201
CAS:<p>GX 201 is a selective NaV1.7 inhibitor, IC50 of < 3.2 nM for hNaV1.7.</p>Formula:C25H27ClF4N2O4SPurity:99.81%Color and Shape:SolidMolecular weight:563EVT-401
<p>EVT-401 (P2X7 receptor antagonist-1), a purinergic P2X7 receptor antagonist, demonstrates efficacy in combating neuroinflammation [1].</p>Formula:C22H20F4N2O3Color and Shape:SolidMolecular weight:436.43-Aminopropylphosphinic acid
CAS:<p>3-Aminopropylphosphinic acid (3-APPA) is a phosphonic analog of gamma-aminobutyric acid (GABA).</p>Formula:C3H10NO2PColor and Shape:SolidMolecular weight:123.092Huwentoxin-IV
CAS:<p>Selective NaV1.7 blocker; also inhibits NaV1.2, 1.3; less effect on NaV1.4, 1.5. Binds to neurotoxin site, traps voltage sensor. IC50: 26-338 nM.</p>Formula:C174H278N52O51S6Purity:98%Color and Shape:SolidMolecular weight:4106.79α5-GABAA receptor modulator 1
<p>α5-GABAA receptor modulator 1 (Compound A-4) is a selective silent allosteric modulator (SAM) targeting the α5 subunit of GABAA receptors, useful for research into central nervous system (CNS) disorders.</p>Formula:C21H20FN3O4Color and Shape:SolidMolecular weight:397.4Tenapanor HCl
CAS:<p>Tenapanor (AZD-1722, RDX 5791) inhibits NHE3 for sodium control in the gut and kidneys.</p>Formula:C50H68Cl6N8O10S2Color and Shape:SolidMolecular weight:1217.97Antidepressant agent 4
<p>Antidepressant agent 4: orally active, has antidepressant, anxiolytic, and nootropic effects.</p>Formula:C19H38ClN5O2SColor and Shape:SolidMolecular weight:436.06GsMTx4
CAS:<p>GsMTx-4, mechanosensitive and stretch-activated ion channel inhibitor (CAS 1209500-46-8).</p>Formula:C185H273N49O45S6Purity:98%Color and Shape:SolidMolecular weight:4095.84Agitoxin-2
CAS:Potent Shaker K+ channel blocker (Ki = 0.64 nM). Also inhibits Kv1.3, Kv1.6 and Kv1.1 K+ channels (Ki values are 4, 37 and 44 pM respectively).Formula:C169H278N54O48S8Purity:98%Color and Shape:SolidMolecular weight:4090.87Way 125971
CAS:<p>Way 125971 is a bioactive chemcial.</p>Formula:C22H28N4O5S2Color and Shape:SolidMolecular weight:492.61Withaphysalin D
CAS:<p>Withaphysalin D, from water lilies, blocks GluN2B NMDARs and is neuroprotective, crossing the blood-brain barrier.</p>Formula:C28H34O6Color and Shape:SolidMolecular weight:466.57PptT-IN-4
<p>PptT-IN-4 (Compound 3a) is a PptT inhibitor exhibiting an IC50 of 0.71 μM.</p>Formula:C17H23N3Purity:98%Color and Shape:SolidMolecular weight:269.38P-gp inhibitor 15
<p>P-gp Inhibitor 15 (compound 7a), a nonsubstrate inhibitor of P-glycoprotein (Pgp), inhibits Pgp-ATPase activity and interferes with Pgp-mediated Rhodamine123</p>Formula:C35H60N2O4Color and Shape:SolidMolecular weight:572.86Isotachysterol 3
CAS:<p>Isotachysterol 3 boosts calcium transport in gut and bone mobilization in kidneyless rats.</p>Formula:C27H44OColor and Shape:SolidMolecular weight:384.64Roquefortine C
CAS:<p>Roquefortine C is a fungal cyclopeptide isolated from Penicillium roquefortii, activates P-gp and also inhibits P450-3A and other haemoproteins</p>Formula:C22H23N5O2Purity:98%Color and Shape:SolidMolecular weight:389.45Budiodarone tartrate
CAS:<p>Budiodarone tartrate (ATI-2042 tartrate) is an antiarrhythmic agent that inhibits calcium channels, and can be used in atrial fibrillation research.</p>Formula:C31H37I2NO11Purity:97.44%Color and Shape:SolidMolecular weight:853.44NMDA agonist 2
<p>NMDA agonist 2 (compound 8d) effectively inhibits NMDA receptors, exhibiting an EC50 of 0.034 μM for GluN1/2C. It plays a significant role in neurological and psychiatric disorders.</p>Formula:C14H12BrFN2O3SColor and Shape:SolidMolecular weight:387.224RU-TRAAK-2
CAS:<p>RU-TRAAK-2 reversibly inhibits TWIK-related K+ channel, inactive on Kv1.2, GIRK2, Slo1.</p>Formula:C19H17N3OSPurity:99.81%Color and Shape:SolidMolecular weight:335.42Sulcardine 2HCl
CAS:<p>Sulcardine 2HCl is a multi-ion channel blocker that blocks the properties of hERG and hNav1.5 channels and can be used to study atrial fibrillation.</p>Formula:C24H35Cl2N3O4SPurity:99.33% - 99.76%Color and Shape:SoildMolecular weight:532.523AChE/Aβ-IN-1
<p>AChE/Aβ-IN-1 (compound 32) is a potent, orally active acetylcholinesterase (AChE) inhibitor with an IC50 of 86 nM and an NMDA receptor antagonist targeting the</p>Formula:C20H25BrN4Color and Shape:SolidMolecular weight:401.34S-Sulfo-L-cysteine sodium salt
CAS:<p>S-Sulfo-L-cysteine sodium salt shows a weak affinity for mGluR1α and mGluR5a at high concentrations and has potential antioxidant activity.</p>Formula:C3H6NNaO5S2Purity:99.88%Color and Shape:SolidMolecular weight:223.2Trapencaine
CAS:<p>Trapencaine is a newly synthesized carbamate type local anesthetic that induces conformational changes in sodium channels on hypertrophic cell membranes.</p>Formula:C22H34N2O3Purity:98.96%Color and Shape:SolidMolecular weight:374.52Solpecainol
CAS:<p>solpecainol is a sodium channel blocker used in the study of neurological and cardiovascular diseases.</p>Formula:C18H23NO3Purity:99.71%Color and Shape:SoildMolecular weight:301.38Indenebart
<p>Indenebart is a humanized IgG1λ2 monoclonal antibody targeting SNCA, with HumanIgG1lambda2, Isotype Control serving as the corresponding isotype control.</p>Color and Shape:Odour LiquidHemitoxin
<p>Hemitoxin, a scorpion-venom peptide, functions as a K+ channel blocker and selectively inhibits rat Kv1.1, Kv1.2, and Kv1.3 channels expressed in Xenopus</p>Formula:C159H259N49O49S8Purity:98%Color and Shape:SolidMolecular weight:3897.58sFTX-3.3
CAS:<p>sFTX-3.3 is a calcium ion channel antagonist, exhibiting IC50 values of approximately 0.24 mM and 0.70 mM against P-type and N-type channels respectively.</p>Formula:C12H29N7OColor and Shape:SolidMolecular weight:287.412Anthopleurin-C
<p>Anthopleurin-C (APE 2-1) is a cardiotonic polypeptide exhibiting a potent positive inotropic effect [1].</p>Formula:C210H316N62O61S6Purity:98%Color and Shape:SolidMolecular weight:4877.52Nicardipine-d3 hydrochloride
CAS:<p>Nicardipine D3 hydrochloride is the deuterium labeled Nicardipine hydrochloride.</p>Formula:C26H30ClN3O6Purity:98%Color and Shape:SolidMolecular weight:519Halofantrine hydrochloride
CAS:<p>Halofantrine hydrochloride (SKF-102886) is an orally administered antimalarial drug effective against drug-resistant P. falciparum and P. vivax. SKF-102886 has cardiac toxicity, inhibiting hERG and delayed rectifier potassium channel I Kr, leading to prolonged QTc and PR intervals.</p>Formula:C26H31Cl3F3NOPurity:98%Color and Shape:SolidMolecular weight:536.89(S)-Nicardipine
CAS:<p>(S)-Nicardipine is the less active S enantiomer of Nicardipine. Nicardipine is a blocker of calcium channel(IC50 of 1 μM for blocking cardiac calcium channels).</p>Formula:C26H29N3O6Color and Shape:SolidMolecular weight:479.53Jedi2
CAS:<p>Jedi2 is a Piezo1 activator rather than a specific Piezo2 activator. Jedi2 binds to the mouse Piezo1 proteins with a K d of 2770 μM [1].</p>Formula:C10H8O3SPurity:97.85%Color and Shape:SolidMolecular weight:208.23β-D-Glucopyranosyl abscisate
CAS:<p>β-D-Glucopyranosyl abscisate (ABA-GE) is a hydrolyzable conjugate of abscisic acid (ABA), which predominantly accumulates in the vacuole and likely in the</p>Formula:C21H30O9Color and Shape:SolidMolecular weight:426.46NS-102
CAS:<p>NS-102 is a glutamate receptor and NMDA receptor antagonist that inhibits erythrocyanine (GluK2) and inhibits specific binding to the glur6 receptor.</p>Formula:C12H11N3O4Purity:98.48% - 98.95%Color and Shape:SolidMolecular weight:261.23Norverapamil-d7
CAS:<p>Norverapamil D7 is a deuterium labeled Norverapamil . Norverapamil is a blocker of L-type calcium channel and an inhibitor of P-glycoprotein (P-gp) function .</p>Formula:C26H36N2O4Purity:98%Color and Shape:SolidMolecular weight:447.62Fluoroethylnormemantine hydrochloride
CAS:<p>Fluoroethylnormemantine HCl, an NMDA receptor antagonist, has anti-amnesic, neuroprotective effects, and is a PET tracer.</p>Formula:C12H21ClFNColor and Shape:SolidMolecular weight:233.764-(4-chlorophenyl)piperidin-4-ol
CAS:<p>Compound Fr13199 is a useful organic compound for research related to life sciences. The catalog number is Fr13199 and the CAS number is 39512-49-7.</p>Formula:C11H14ClNOPurity:99.63%Color and Shape:White Slight Beige Solid Solid Particulate/PowderMolecular weight:211.688Phenazopyridine
CAS:<p>Phenazopyridine is an orally administered azo dye with local analgesic effects on urinary tract infections,. against SARM1 and TRPM8.</p>Formula:C11H11N5Purity:99.98%Color and Shape:SolidMolecular weight:213.24Perfluoroenanthic acid
CAS:<p>Perfluoroenanthic acid (Perfluoroheptanoic acid) is a perfluoroalkyl substance (PFAS) that negatively impacts spermatogenic development and testicular m6A RNA methylation in offspring exposed during gestation, thus impeding spermatogenesis and inducing reproductive toxicity. Additionally, in primary cortical neuron cultures, Perfluoroenanthic acid alters dendritic spine morphology and synaptogenesis, enhances neural activity and synaptic transmission, and increases the expression of excitatory synapse-associated proteins Synaptophysin and PSD95.</p>Formula:C7HF13O2Color and Shape:SolidMolecular weight:364.06Dipropofol
CAS:<p>Dipropofol (4,4-Bis(2,6-di-isopropylphenol)) is a small molecule GABAA receptor agonist that can be used to study epilepsy.</p>Formula:C24H34O2Purity:99.51%Color and Shape:SolidMolecular weight:354.53NS 383
CAS:<p>ASIC blocker with varying IC50: 0.12 μM in hASIC1a, and ineffective on hASIC2a/3; <5 μM on rASIC1a/2a/3; alleviates pain in inflamed/CCI rats.</p>Formula:C19H19N3O2Color and Shape:SolidMolecular weight:321.37MSC-4381
CAS:<p>MSC-4381 (MCT4-IN-1) is an orally available and selectively modeled highly potent inhibitor of monocarboxylic acid transporter protein 4 (MCT4/SLC16A3) with potential anticancer and antitumor activity for the study of osteosarcoma.</p>Formula:C26H20ClN3O6SPurity:99.04%Color and Shape:SolidMolecular weight:537.97Propanidid
CAS:<p>Propanidid (Sombrevin) is a gamma-aminobutyric acid type A receptor (GABAA) agonist and an intravenous anesthetic that lowers arterial blood pressure.</p>Formula:C18H27NO5Purity:99.64%Color and Shape:SolidMolecular weight:337.41BI-9627
CAS:<p>BI-9627 is an inhibitor of sodium-hydrogen exchanger isoform 1 (NHE1) (EC50: 31 nM).</p>Formula:C16H19F3N4O2Purity:99.77%Color and Shape:SolidMolecular weight:356.34GYKI 52466 dihydrochloride
CAS:<p>GYKI 52466 dihydrochloride is an AMPA/Kainate receptor antagonist with anticonvulsant activity and can be used to study neurological diseases.</p>Formula:C17H17Cl2N3O2Purity:99.38%Color and Shape:SolidMolecular weight:366.24Padsevonil
CAS:<p>Padsevonil (UCB-0942) is a potential GABA A receptor orthosteric modulator with antiepileptic activity for the treatment of epilepsy.</p>Formula:C14H14ClF5N4O2SPurity:99.63%Color and Shape:SolidMolecular weight:432.80(R)-3-Amino-4-hydroxybutanoic acid
CAS:<p>(R)-3-Amino-4-hydroxybutanoic acid,L-beta-Homoserine, is a full agonist at the human recombinant rho1 GABAC receptor, a modulator of GABAA and GABAB receptors.</p>Formula:C4H9NO3Purity:99.92%Color and Shape:SolidMolecular weight:119.12Cromakalim
CAS:<p>Cromakalim (BRL 34915) is an ATP-dependent K(+) channel opener, a smooth muscle relaxant with antiepileptic activity.</p>Formula:C16H18N2O3Purity:99.39%Color and Shape:SolidMolecular weight:286.33L-3373
CAS:<p>L-3373 is a competitive T3 (3,5,3'-triiodothyronine) antagonist with IC₅₀ values of 38 and 36 nM for alpha1-T3R and beta1-T3R, respectively.</p>Formula:C19H16I2O3Purity:99.85%Color and Shape:Off-White SolidMolecular weight:546.14Fanapanel hydrate
CAS:<p>Fanapanel hydrate selectively blocks AMPA/kainate over NMDA; Ki: 3.2 nM (quisqualate), 100 nM (kainate), 8.5 μM (NMDA).</p>Formula:C14H17F3N3O7PColor and Shape:SolidMolecular weight:427.27Piretanide
CAS:<p>Piretanide, an oral loop diuretic, effective and potassium-sparing, heart failure and hypertension with reduced electrolyte imbalance risk.</p>Formula:C17H18N2O5SColor and Shape:Pale Yellow PowderMolecular weight:362.4MDL 105519
CAS:<p>MDL 105519 is a selective, non-competitive antagonist of NMDA receptors. It inhibits cyclic GMP accumulation in brain slices, anxiolytic in rat models.</p>Formula:C18H11Cl2NO4Color and Shape:SolidMolecular weight:376.19Naminidil
CAS:<p>Naminidil is an opener of cyanoguanidine KATP.</p>Formula:C15H19N5Purity:98%Color and Shape:SolidMolecular weight:269.34Furosemide-d5
CAS:<p>Furosemide-d5 is a deuterium marker for Furosemide and used in isotope tracer experiments. orally active inhibitor of Na+/K+/2Cl- (NKCC) diuretic reagent.</p>Formula:C12H11ClN2O5SColor and Shape:SolidMolecular weight:335.78Lesinurad sodium
CAS:<p>Lesinurad sodium (RDEA594 sodium) is a selective inhibitor of uric acid reabsorption and is used in the study of cardiovascular diseases.</p>Formula:C17H13BrN3NaO2SPurity:99.97%Color and Shape:SolidMolecular weight:426.26Flecainide
CAS:<p>Flecainide is an orally administered antiarrhythmic agent acting as a sodium channel blocker and IKr inhibitor,PSVT.</p>Formula:C17H20F6N2O3Purity:99.896%Color and Shape:SolidMolecular weight:414.345-Hydroxydecanoic acid
CAS:<p>5-Hydroxydecanoic acid is a selective ATP-sensitive K+ (KATP) channel blocker (IC50 of ~30 μM). 5-Hydroxydecanoic acid is a substrate for mitochondrial outer membrane acyl-CoA synthetase and has antioxidant activity.</p>Formula:C10H20O3Purity:99.24%Color and Shape:SolidMolecular weight:188.26γ-DGG
CAS:<p>gamma-DGG is a competitive blocker of AMPA receptor.</p>Formula:C7H12N2O5Purity:98%Color and Shape:SolidMolecular weight:204.18Lansoprazole Sulfide D4
CAS:<p>Lansoprazole Sulfide D4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC50 values of 0.59 μM intracellularly and 0.46 μM in broth.Lansoprazole Sulfide is an active metabolite of the proton pump inhibitor Lansoprazole.</p>Formula:C16H14F3N3OSPurity:98%Color and Shape:SolidMolecular weight:357.39(S)-Lercanidipine D3 hydrochloride
CAS:<p>(S)-Lercanidipine D3 hydrochloride is a deuterium labeled Lercanidipine D3 hydrochloride. (S)-Lercanidipine hydrochloride is an agent of antihypertensive.</p>Formula:C36H42ClN3O6Purity:98%Color and Shape:SolidMolecular weight:651.21Etifoxine
CAS:<p>Etifoxine targets β2/β3 GABAA receptors, is anxiolytic in humans/rodents, boosts GABAA, binds TSPO, aids axon regeneration, no sedative effects.</p>Formula:C17H17ClN2OPurity:98%Color and Shape:SolidMolecular weight:300.78PF-05198007
CAS:<p>PF-05198007 is a compound with a similar pharmacodynamic profile to PF-05089771. PF-05198007 is an effective and selective arylsulfonamide Nav1.7 inhibitor.</p>Formula:C19H12ClF4N5O3S2Purity:98%Color and Shape:SolidMolecular weight:533.91Rapastinel
CAS:<p>Rapastinel (TPPT-amide) (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator.</p>Formula:C18H31N5O6Purity:97.18%Color and Shape:SolidMolecular weight:413.47L-655708
CAS:<p>L-655708 is a selective and highly potent GABAA receptor reverse agonist with a Ki value of 0.45 nM.</p>Formula:C18H19N3O4Purity:98.41%Color and Shape:PowderMolecular weight:341.36Naspm
CAS:<p>Naspm is a synthetic analogue of Joro spider toxin and is a antagonist iscalcium permeable AMPA (CP-AMPA) receptors.</p>Formula:C22H34N4OPurity:98%Color and Shape:SolidMolecular weight:370.53KCNQ1 activator-1
CAS:<p>N-[4-(4-Methoxyphenyl)-2-thiazolyl]-2-piperidinecarboxamide is a potent KCNQ1 activator for LQTS research.</p>Formula:C22H23N3O4S2Purity:99.71%Color and Shape:SolidMolecular weight:457.57Ethacizine hydrochloride
CAS:<p>Ethacizine hydrochloride (NIK-244) has antiarrhythmic activity and can be used to study arrhythmias and myocardial infarction.</p>Formula:C22H28ClN3O3SPurity:98.08% - 98.08%Color and Shape:SolidMolecular weight:449.99MRK-016
CAS:MRK-016 is a selective GABAA α5 receptor inverse agonist/ negative allosteric modulator, orally available and penetrating the BBB. MRK-016 is antidepressant.Formula:C17H20N8O2Purity:99.76%Color and Shape:SolidMolecular weight:368.39BTD
CAS:<p>BTD is a TRPC5 activator that activates heteromeric channel complexes composed of TRPC5 and its closest relatives TRPC1 or TRPC4.</p>Formula:C24H33N3O4SColor and Shape:SolidMolecular weight:459.6AM-2099
CAS:<p>AM-2099 is a selective voltage-gated sodium channel Nav1.7 inhibitor used in pain research.</p>Formula:C19H13F3N4O3S2Color and Shape:SolidMolecular weight:466.46Vigabatrin Hydrochloride
CAS:<p>Vigabatrin Hydrochloride (γ-Vinyl-GABA hydrochloride) is a structural analog of the GABA, irreversibly inhibiting the catabolism of GABA by GABA transaminase.</p>Formula:C6H11NO2·HClPurity:98%Color and Shape:SolidMolecular weight:165.62Ethyl tosylcarbamate
CAS:<p>Gliclazide blocks beta-cell ATP-sensitive K+ currents, IC50: 184 nM. Ethyl tosylcarbamate is a synthesis intermediate.</p>Formula:C10H13NO4SColor and Shape:SolidMolecular weight:243.28H-D-Allo-Ile-OH
CAS:<p>H-D-Allo-Ile-OH inhibits 3[H] gabapentin binding/voltage-dependent L-type calcium channels and can be used for studying neurological and psychiatric disorders.</p>Formula:C6H13NO2Purity:99.92%Color and Shape:SolidMolecular weight:131.17CGP 36742
CAS:<p>CGP 36742 blocks GABAB receptor, crosses blood-brain barrier, aids depression treatment (IC50: 32 μM).</p>Formula:C7H18NO2PColor and Shape:SolidMolecular weight:179.2Neosolaniol
CAS:<p>Neosolaniol, a type A trichothecene mycotoxin produced by Fusarium species, strongly induces an anorectic (loss of appetite) response.</p>Formula:C19H26O8Purity:98%Color and Shape:SolidMolecular weight:382.4Valnoctamide
CAS:<p>Valnoctamide (Valmethamide) has antiepileptic and anticonvulsant activity and may be used in the study of neurological disorders.</p>Formula:C8H17NOPurity:98%Color and Shape:SolidMolecular weight:143.23Bamaquimast
CAS:<p>Bamaquimast (L 0042) is a proton pump inhibitor for the study of asthma-like immune system disorders and respiratory diseases.</p>Formula:C16H21N3O3Purity:98.47%Color and Shape:SolidMolecular weight:303.36Mepivacaine
CAS:<p>Mepivacaine (Carbocaine) is an amide local anesthetic, blocking sodium channels for nerve blocks and epidurals.</p>Formula:C15H22N2OPurity:99.35%Color and Shape:SolidMolecular weight:246.35GYKI 53655 hydrochloride
CAS:<p>GYKI 53655 hydrochloride (LY300168 hydrochloride) is an antagonist of AMPA and is used in the study of neurological disorders.</p>Formula:C19H21ClN4O3Purity:98.02%Color and Shape:SolidMolecular weight:388.85β-Cyfluthrin
CAS:<p>β-Cyfluthrin is a type II synthetic pyrethroid compound commonly utilized as an active ingredient in agricultural insecticide products.</p>Formula:C22H18Cl2FNO3Color and Shape:SolidMolecular weight:434.29Lubiprostone hemiketal
CAS:Lubiprostone (hemiketal) (RU-0211 (hemiketal)), a selective activator of the chloride channel 2 (CLCN2), facilitates the treatment of chronic idiopathic constipation and opioid-induced constipation. It functions by enhancing CLCN2 channel activity, which boosts chloride ion secretion in the intestines, subsequently increasing fluid secretion and improving intestinal peristalsis. Additionally, Lubiprostone (hemiketal) may be utilized in research related to chronic constipation and cancer.Formula:C20H32F2O5Color and Shape:SolidMolecular weight:390.46Crinecerfont hydrochloride
CAS:<p>SSR-125543, a potent CRF1 receptor non-peptide antagonist, effective in CAH research, taken orally.</p>Formula:C27H29Cl2FN2OSColor and Shape:SolidMolecular weight:519.5(R)-BPO-27
CAS:(R)-BPO-27 is an orally active and potent ATP-competitive CFTR inhibitor (IC50: 4 nM) for the study of diarrhoea and polycystic kidney.Formula:C26H18BrN3O6Purity:99.1%Color and Shape:SolidMolecular weight:548.34Flumazenil acid
CAS:<p>Flumazenil is an antagonist of GABAA receptor. Flumazenil acid is a metabolite of Flumazenil.</p>Formula:C13H10FN3O3Color and Shape:SolidMolecular weight:275.24Tetrabenazine-d6
CAS:<p>Tetrabenazine D6 is the deuterium-labeled Tetrabenazine. Tetrabenazine is a VMAT-inhibitor used for the treatment of hyperkinetic movement disorder.</p>Formula:C19H27NO3Purity:98%Color and Shape:SolidMolecular weight:323.46(+)-SJ733
CAS:<p>(+)-SJ733 (SJ000557733) is a potent Na+-ATPase PfATP4 inhibitor with antimalarial activity for the study of malaria.</p>Formula:C24H16F4N4O2Purity:99.21%Color and Shape:SolidMolecular weight:468.4VU041
CAS:<p>VU041 inhibits mosquito Kir1 channels (IC50: An. gambiae 2.5μM, Ae. aegypti 1.7μM), less on mammalian Kir2.1 (12.7μM), and minimally on other Kir channels.</p>Formula:C19H20F3N3OPurity:98%Color and Shape:SolidMolecular weight:363.38YM-244769 dihydrochloride
CAS:<p>YM-244769 dihydrochloride is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3) with an IC50 of 18 nM.</p>Formula:C26H24Cl2FN3O3Purity:98%Color and Shape:SolidMolecular weight:516.39(R)-Tegoprazan
CAS:<p>(R)-Tegoprazan, a benzimidazole derivative, inhibits kidney H+/K+-ATPase (IC50: 98 nM). Potential in GI disease research.</p>Formula:C20H19F2N3O3Color and Shape:SolidMolecular weight:387.38PF-04856264
CAS:<p>PF-04856264 is a Nav1.7 blocker.,modulates intracellular Ca 2+ signaling and chondrocyte secretome, raises the threshold of mechanical pain analgesic.</p>Formula:C20H15N5O3S2Purity:97.43%Color and Shape:SolidMolecular weight:437.5(R)-Lercanidipine-d3 hydrochloride
CAS:<p>(R)-lercanidipine D3 hydrochloride is a deuterium labeled (R)-Lercanidipine hydrochloride. (R)-Lercanidipine D3 (hydrochloride) is a calcium channel blocker.</p>Formula:C36H42ClN3O6Purity:98%Color and Shape:SolidMolecular weight:651.21Pirmenol hydrochloride
CAS:<p>Pirmenol hydrochloride functions by inhibiting I_K.ACh through the blockade of muscarinic receptors, demonstrating a potent effect with an IC_50 value of 0.1 μM</p>Formula:C22H31ClN2OColor and Shape:SolidMolecular weight:374.95Clamikalant sodium
CAS:<p>Clamikalant sodium (HMR 1098) is an ATP-dependent potassium channel (KATP) cardiac-selective blocker, used in the study of arrhythmias.</p>Formula:C19H21ClN3NaO5S2Purity:99.95%Color and Shape:SolidMolecular weight:493.96GI-530159
CAS:<p>TREK1/2 activator, selective over TRAAK/TASK3; hyperpolarizes neurons, depresses activity (EC50 = 0.76 μM).</p>Formula:C27H20F6N2O2Color and Shape:White CrystalsMolecular weight:518.45(-)-α-Pinene
CAS:<p>(-)-α-Pinene ((1S)-(-)-Alpha-Pinene) enhances the quantity of NREMS without affecting the intensity of NREMS by prolonging GABAergic synaptic transmission,</p>Formula:C10H16Purity:98.02% - 98.60%Color and Shape:Colourless LiquidMolecular weight:136.23QO-58
CAS:<p>QO-58 is a novel Kv7 activator (opener) that activates neuronal Kv7/KCNQ/M channels, danti-nociceptive effects on inflammatory pain</p>Formula:C18H8Cl2F4N4OPurity:99.17%Color and Shape:SolidMolecular weight:443.18Benzocaine hydrochloride
CAS:<p>Benzocaine hydrochloride (Ethyl 4-aminobenzoate hydrochloride) is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and</p>Formula:C9H11NO2·HClPurity:98%Color and Shape:SolidMolecular weight:201.65MRS1845
CAS:<p>MRS1845 is a selective inhibitor of store-operated calcium (SOC) channel (IC50 of 1.7 μM).</p>Formula:C21H22N2O6Purity:99.69%Color and Shape:SolidMolecular weight:398.41Triamterene D5
CAS:<p>Triamterene D5 is a deuterium-labeled Triamterene and can block epithelial Na+ channel (ENaC) in a voltage-dependent manner, used as a mild diuretic.</p>Formula:C12H11N7Purity:98%Color and Shape:SolidMolecular weight:258.29Luciferase, firefly
CAS:<p>Luciferase, firefly is a reporter gene in cellular imaging studies to quantify target gene expression levels and measure intracellular ATP content,</p>Purity:98%Color and Shape:SolidMolecular weight:N/ATetramethrin
CAS:<p>Tetramethrin is a type I pyrethroid insecticide that affects the inactivation process of sodium channels in insect neurons, prolonged sodium currents.</p>Formula:C19H25NO4Purity:98.85%Color and Shape:White Crystals Or PowderMolecular weight:331.41L-364,373
CAS:<p>KV7.1 (KCNQ1) channel activator</p>Formula:C25H20FN3OColor and Shape:SolidMolecular weight:397.44Poneratoxin acetate
<p>Poneratoxin acetate is a neurotoxic peptide and modulator of NaV1.6/NaV1.7, lowering the activation threshold of voltage-gated sodium channels and causing pain.</p>Formula:C129H215N33O31S·xC2H4O2Color and Shape:SolidMolecular weight:2756.35 (free base)SDZ 220-581 hydrochloride
CAS:<p>SDZ 220-581 hydrochloride is a potent, orally active and competitive antagonist of NMDA receptor(pKi : 7.7).</p>Formula:C16H18Cl2NO5PPurity:98%Color and Shape:SolidMolecular weight:406.2Dibucaine hydrochloride
CAS:<p>Dibucaine hydrochloride (Cinchocaine hydrochloride), a long-acting local amide anestheticsis, is usually used for surface anesthesia.</p>Formula:C20H30ClN3O2Purity:99.66%Color and Shape:White PowderMolecular weight:379.92BI-9627 hydrochloride
CAS:<p>BIX HCl is a sodium-hydrogen exchange type 1 inhibitor.</p>Formula:C16H20ClF3N4O2Color and Shape:SolidMolecular weight:392.8HSK16149
CAS:<p>HSK16149 is a novel ligand of voltage-gated calcium channel (VGCC) α 2 δ subunit with analgesic activity.</p>Formula:C12H19NO2Color and Shape:SolidMolecular weight:209.28SDZ 220-581 Ammonium salt
CAS:<p>SDZ 220-581 Ammonium salt is a potent, orally active and competitive antagonist of NMDA receptor(pKi : 7.7).</p>Formula:C16H20ClN2O5PPurity:98%Color and Shape:SolidMolecular weight:386.77TACA
CAS:<p>GABAA agonist</p>Formula:C4H7NO2Purity:98%Color and Shape:White SolidMolecular weight:101.1Lansoprazole-d4
CAS:<p>Lansoprazole D4 (AG-1749 D4) is a deuterium labeled Lansoprazole. Lansoprazole is an inhibitor of proton pump which prevents the stomach from producing acid.</p>Formula:C16H14F3N3O2SPurity:98%Color and Shape:SolidMolecular weight:373.39(R)-Nicardipine
CAS:<p>(R)-Nicardipine is the less active R enantiomer of Nicardipine. Nicardipine is a blocker of calcium channel(IC50 of 1 μM for blocking cardiac calcium channels).</p>Formula:C26H29N3O6Color and Shape:SolidMolecular weight:479.53L-Palmitoylcarnitine
CAS:<p>L-Palmitoylcarnitine (L-PC) inhibits Na/K ATPase activity and potentiates fibrinolytic enzymes and tPA to inhibit thrombosis.</p>Formula:C23H45NO4Purity:97% - 99.81%Color and Shape:SolidMolecular weight:399.61Cabotegravir sodium
CAS:<p>Cabotegravir sodium inhibits HIV integrase (IC50: 2.5 nM), metabolized by UGT1A1, with minimal ARV interaction.</p>Formula:C19H16F2N3NaO5Color and Shape:SolidMolecular weight:427.34SDZ 220-581
CAS:<p>SDZ 220-581 is a potent, orally active and competitive antagonist of NMDA receptor(pKi : 7.7).</p>Formula:C16H17ClNO5PPurity:98%Color and Shape:SolidMolecular weight:369.74Nateglinide D5
CAS:<p>Nateglinide D5 is a deuterium labeled Nateglinide.</p>Formula:C19H27NO3Purity:98%Color and Shape:SolidMolecular weight:322.4517β-Estradiol sulfate sodium
CAS:<p>17β-Estradiol sulfate sodium (17β-Estradiol 3-sulfate sodium) is a neuroactive estrogen with vasoprotective properties that inhibits the growth of Neisseria brasiliensis and disrupts aquatic ecosystems.</p>Formula:C18H23NaO5SPurity:99%Color and Shape:SolidMolecular weight:374.43TGN-073
CAS:<p>TGN-073 is an enhancer of aquaporin 4 (AQP4), a water channel in astrocytes. It shows an increase in lymphatic transport in the rat brain by up to 41%.</p>Formula:C18H16N2O3SColor and Shape:SolidMolecular weight:340.396SKA-121
CAS:<p>SKA-121 is a selective KCa3.1 activator (EC50s: 109 nM and 4.4 μM for KCa3.1 and KCa2.3, respectively).</p>Formula:C12H10N2OPurity:98%Color and Shape:SolidMolecular weight:198.22Mexiletine-d6 hydrochloride
CAS:<p>Mexiletine D6 hydrochloride is a non-selective voltage-gated sodium channel blocker,is a Class IB antianhythmic.</p>Formula:C11H18ClNOPurity:98%Color and Shape:SolidMolecular weight:221.76N-Methyl-DL-aspartic acid
CAS:<p>N-Methyl-DL-aspartic acid, a glutamate analogue and NMDA receptor agonist, is utilized in neurological disease research.</p>Formula:C5H9NO4Purity:99.85%Color and Shape:SolidMolecular weight:147.13UBP608
CAS:<p>UBP608 selectively inhibits NMDA GluN1/GluN2A receptors, 23x more than GluN1/GluN2D.</p>Formula:C10H5BrO4Color and Shape:SolidMolecular weight:269.05YM-244769
CAS:<p>YM-244769 (3-Pyridinecarboxamide, N-[(3-aminophenyl)methyl]-6-[4-[(3-fluorophenyl)methoxy]phenoxy]-) is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3)</p>Formula:C26H22FN3O3Purity:95.62%Color and Shape:SolidMolecular weight:443.473,3-Diethylthiacarbocyanine iodide
CAS:<p>3, 3-diethylthiacarbocyanine iodide is a cyanine dye. Can be used for photochemical methods.</p>Formula:C21H21IN2S2Purity:99.79%Color and Shape:SolidMolecular weight:492.44Eperisone hydrochloride
CAS:<p>Eperisone is a skeletal muscle relaxant and a spasmolytic agent related structurally to Tolperisone.</p>Formula:C17H26ClNOPurity:99.80%Color and Shape:White Or Similar To White Crystalline Powder With Peculiar Smell And Bitter TasteMolecular weight:295.85Evifacotrep
CAS:<p>Evifacotrep: TRPC5 antagonist for neurological disease research (WO2020061162, compound 100).</p>Formula:C18H12ClF4N5O2Purity:98.6%Color and Shape:SolidMolecular weight:441.77YHO-13177
CAS:<p>YHO-13177 is a potent and specific inhibitor of BCRP; potentiated the cytotoxicity of SN-38 in cancer cells.</p>Formula:C20H22N2O3SPurity:98.78%Color and Shape:SolidMolecular weight:370.47HC-030031
CAS:<p>HC-030031 (TOSLAB 829227) is a potent TRPA1 inhibitor, which antagonizes AITC- and formalin-evoked calcium influx with IC50s of 6.2 and 5.3 μM, respectively.</p>Formula:C18H21N5O3Purity:99.69% - ≥95%Color and Shape:SolidMolecular weight:355.39CCTA-1523
CAS:<p>CCTA-1523 is an efflux function of ABCG2 inhibitor. CCTA-1523 selectively reverses ABCG2-mediated MDR in cancer cells.</p>Formula:C16H15Cl2NO3Purity:99.71%Color and Shape:SolidMolecular weight:340.2VU0134992
CAS:<p>VU0134992 is an Kir4.1 blocker with an IC50 value of 0.97 μM</p>Formula:C20H31BrN2O2Purity:99.86%Color and Shape:SolidMolecular weight:411.38Cis-ACBD
CAS:<p>Cis-ACBD (cis-1-aminocyclobutane-1,3-dicarboxylic acid) is a potent and selective N-methyl-D-aspartate receptor agonist.</p>Formula:C6H9NO4Purity:99.77%Color and Shape:SolidMolecular weight:159.14Omecamtiv mecarbil
CAS:<p>Omecamtiv mecarbil (CK-1827452) has been used in trials studying the treatment and basic science of Heart Failure, Echocardiogram, Pharmacokinetics, Chronic</p>Formula:C20H24FN5O3Purity:98% - 99.23%Color and Shape:SolidMolecular weight:401.43Dotinurad
CAS:<p>Dotinurad ((3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone) is a potent agent of uricosuric (IC50: 3.6 μM for uric acid).</p>Formula:C14H9Cl2NO4SPurity:97.43% - 98.04%Color and Shape:SolidMolecular weight:358.2BzATP triethylammonium salt
CAS:<p>BzATP triethylammonium salt is a P2X7 receptor agonist.</p>Formula:C30H39N6O15P3Purity:95% - 99.57%Color and Shape:SolidMolecular weight:816.59(S)-ATPO
CAS:<p>(S)-ATPO is Competitive antagonist at GluR1-4 (AMPA-preferring) receptors.</p>Formula:C11H19N2O7PPurity:98.37% - 99.41%Color and Shape:SolidMolecular weight:322.25Procyclidine hydrochloride
CAS:<p>Procyclidine hydrochloride ((±)-Procyclidine hydrochlorid) is a potent anticholinergic agent and also have NMDA antagonist properties.</p>Formula:C19H30ClNOPurity:99.24% - 99.88%Color and Shape:Crystals From Petroleum Ether White PowderMolecular weight:323.9DL-Menthol
CAS:<p>DL-Menthol ((±)-Menthol) is a racemic mixture of the monoterpene alcohols (–)-menthol and (+)-menthod, which have been found in Cannabis.</p>Formula:C10H20OPurity:99.74%Color and Shape:White Crystals /89-78-1/ Physical Description White Crystalline Solid With A Peppermint Odor And Taste (Ntp 1992)Molecular weight:156.27γ-Acetylenic GABA
CAS:<p>γ-Acetylenic GABA (4-Aminohex-5-ynoic acid) is a potent, irreversible inhibitor of GABA-transaminase.</p>Formula:C6H9NO2Color and Shape:SolidMolecular weight:127.143Pikamilone
CAS:<p>Pikamilone (Picamilon) is an intelligent medicine.</p>Formula:C10H12N2O3Purity:99.38%Color and Shape:White Crystalline PowderMolecular weight:208.21UBP551
CAS:<p>UBP551 is a potent and selective NMDA receptors modulator.</p>Formula:C11H8O4Purity:98.69%Color and Shape:SolidMolecular weight:204.18DAAO inhibitor-1
CAS:<p>DAAO inhibitor-1 is a potent D-amino acid oxidase (DAAO) inhibitor (IC50: 0.12 μM).</p>Formula:C7H5FN2OPurity:97.84%Color and Shape:SolidMolecular weight:152.13Argireline
CAS:<p>Argireline (Acetyl hexapeptide-3) is a peptide that inhibits neurotransmitter release, reducing wrinkles.</p>Formula:C34H60N14O12SPurity:96.79% - 99.65%Color and Shape:White PowderMolecular weight:888.99OAC3
CAS:<p>OAC3 (4-fluoro-N-(1H-indol-5-yl)benzamide) is an activator of octamer-bound transcription factor 4.</p>Formula:C15H11FN2OPurity:97.13%Color and Shape:SolidMolecular weight:254.26Myomodulin acetate(110570-93-9 free base)
<p>Myomodulin acetate is present in two identified aplysia neurons that contain myomodulin A the ARC motor neuron B16 and the abdominal neuron L10.</p>Formula:C38H71N11O10S2Purity:99.24%Color and Shape:SolidMolecular weight:906.17Raxatrigine
CAS:<p>Raxatrigine (CNV 1014802) has been investigated for the treatment of Bipolar Disorder and Bipolar Depression.</p>Formula:C18H19FN2O2Purity:98% - 99.43%Color and Shape:SolidMolecular weight:314.35Mitiglinide calcium hydrate
CAS:<p>Mitiglinide calcium hydrate (S-21403 calcium hydrate) is a drug for the treatment of type 2 diabetes.</p>Formula:C38H52CaN2O8Purity:98.97% - 99.96%Color and Shape:White SolidMolecular weight:704.91HC067047 Hydrochloride(883031-03-6 free base)
CAS:<p>HC-067047 hydrochloride, a TRPV4 antagonist, selectively inhibits human, rat, and mouse currents with IC50s: 486 nM, 133 nM, and 17 nM.</p>Formula:C26H29ClF3N3O2Purity:99.95%Color and Shape:SolidMolecular weight:507.98Ivacaftor
CAS:<p>Ivacaftor (VX-770) (VX-770) is a potentiator of CFTR targeting G551D-CFTR (EC50: 100 nM) and F508del-CFTR (EC50: 25 nM) in Fisher rat thyroid cells,</p>Formula:C24H28N2O3Purity:99% - 99.98%Color and Shape:SolidMolecular weight:392.49NPPB
CAS:<p>NPPB is a chloride channel blocker with IC50 of 80 nM .</p>Formula:C16H16N2O4Purity:99.95%Color and Shape:Light Yellow To Yellow SolidMolecular weight:300.31NBQX
CAS:<p>NBQX (FG9202) is a potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.</p>Formula:C12H8N4O6SPurity:97.66% - 99.42%Color and Shape:SolidMolecular weight:336.286-Methylflavone
CAS:<p>6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors.</p>Formula:C16H12O2Purity:99.69%Color and Shape:SolidMolecular weight:236.27Ononetin
CAS:<p>Ononetin (2',4'-Dihydroxy-2-(4-methoxyphenyl)acetophenone) is a TRPM3 channel blocker(IC50: 0.3 μM).</p>Formula:C15H14O4Purity:98.06%Color and Shape:SolidMolecular weight:258.27Vonoprazan
CAS:<p>Vonoprazan (TAK-438 (free base)) is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer and</p>Formula:C17H16FN3O2SPurity:99.87% - 99.92%Color and Shape:SolidMolecular weight:345.39TRPM8 antagonist WS-3
CAS:<p>TRPM8 antagonist WS-3 (Cyclohexanecarboxamide) is an agonist of TRPM8( EC50 : 3.7 μM).</p>Formula:C13H25NOPurity:97.64%Color and Shape:DrypowderMolecular weight:211.34SG-209
CAS:<p>SG 209 is an analog of nicorandil and acts as a K+ channel opener and nitrate-free coronary vasodilator.</p>Formula:C10H12N2O3Purity:99.84%Color and Shape:SolidMolecular weight:208.21AZ194
CAS:<p>CRMP2-Ubc9-NaV1.7 inhibitor 194, is a CRMP2-Ubc9-NaV1.7 inhibitor.</p>Formula:C34H31F2N3O3Purity:99.61%Color and Shape:SolidMolecular weight:567.62ICA-121431
CAS:<p>ICA-121431: a potent Nav1.7 inhibitor (IC50=19 nM for rat), minimal effect on human Nav1.5/Nav1.7.</p>Formula:C23H19N3O3S2Purity:98.06%Color and Shape:SolidMolecular weight:449.55SAR7334 hydrochloride
CAS:<p>SAR7334 hydrochloride is a potent and specific inhibitor of TRPC6(IC50 of 7.9 nM).</p>Formula:C21H24Cl3N3OPurity:98%Color and Shape:SolidMolecular weight:440.79Selinexor (KPT-330)
CAS:<p>Selinexor (KPT-330) is an orally available, small molecule inhibitor of CRM1 (exportin 1 or XPO1), with potential antineoplastic activity.</p>Formula:C17H11F6N7OPurity:98% - 99.97%Color and Shape:SolidMolecular weight:443.31Flupirtine maleate
CAS:<p>Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. Flupirtine is an NMDA receptor antagonist.</p>Formula:C15H17FN4O2·C4H4O4Purity:99.5% - 99.9%Color and Shape:Off-White Crystalline PowderMolecular weight:420.39Homo-VK-II-36
CAS:<p>Homo-VK-II-36 (Homo-V-II-36) is a carvedilol analogue that acts by inhibiting store- overload-induced calcium release through the RyR2 channel.</p>Formula:C27H28N2O5Purity:99.26%Color and Shape:SolidMolecular weight:460.527-Chlorokynurenic acid sodium salt
CAS:<p>7-CKA sodium salt: NMDA receptor antagonist, glycine B site (IC50: 0.56 μM), blocks glutamate reuptake (Ki: 0.59 μM).</p>Formula:C10H6ClNNaO3Color and Shape:SolidMolecular weight:246.6α-Cyano-4-hydroxycinnamic acid
CAS:<p>α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamic acid(α-CHCA)) (α-CHCA) is an inhibitor of monocarboxylate transporter 1 (MCT1) that blocks pyruvate</p>Formula:C10H7NO3Purity:99.8% - 99.86%Color and Shape:PowderMolecular weight:189.17Thonzonium Bromide
CAS:<p>Thonzonium bromide: antimicrobial surfactant, similar to Farnesol, blocks proton transport, inhibits bone loss (EC50=69 μM).</p>Formula:C32H55BrN4OPurity:98.48% - 99.94%Color and Shape:SolidMolecular weight:591.71Linerixibat
CAS:<p>Linerixibat (GSK2330672) is a highly effective, nonabsorbable ASBT inhibitor. Linerixibat can lower glucose in an animal model of type 2 diabetes.</p>Formula:C28H38N2O7SPurity:98.5% - 99.98%Color and Shape:SolidMolecular weight:546.68ML365
CAS:<p>ML365 is a novel selective small molecule inhibitor of TASK1(KCNK3).</p>Formula:C22H20N2O3Purity:98.78%Color and Shape:SolidMolecular weight:360.41Vanilloid receptor antagonist 1
CAS:<p>Vanilloid receptor antagonist 1 (4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile) is a potent vanilloid receptor TRPV1 antagonist.</p>Formula:C18H15N3O2Purity:98.14%Color and Shape:SolidMolecular weight:305.33Zoniporide hydrochloride hydrate
CAS:<p>Zoniporide HCl hydrate: selective NHE-1 inhibitor with a 14 nM IC50.</p>Formula:C17H19ClN6O2Purity:98%Color and Shape:SolidMolecular weight:374.83SB-366791
CAS:<p>SB-366791 is a new and selective cinnamide TRPV1 antagonist.</p>Formula:C16H14ClNO2Purity:99.51%Color and Shape:SolidMolecular weight:287.74Optovin
CAS:<p>Optovin is a TRPA1 activator, which is reversibly photoactivated.</p>Formula:C15H13N3OS2Purity:99.47% - 99.67%Color and Shape:SolidMolecular weight:315.41Guan-fu base A hydrochloride(1394-48-5 free base)
CAS:<p>Guanfu base A HCl, an antiarrhythmic from Aconitum coreanum, inhibits CYP2D6 in humans, monkeys, and dogs.</p>Formula:C24H32NO6ClPurity:99.9%Color and Shape:SolidMolecular weight:465.97Vocacapsaicin
CAS:<p>Vocacapsaicin (CA-008), a prodrug of Capsaicin and a first-in-class non-opioid TRPV1 agonist, offers significant and enduring pain relief.</p>Formula:C26H41N3O4Color and Shape:SolidMolecular weight:459.631N-Me-aminopyrimidinone9
CAS:<p>N-Me-aminopyrimidinone9 is a sodium channel antagonist</p>Formula:C16H21N3OSPurity:99.21%Color and Shape:SolidMolecular weight:303.42SKA-31
CAS:<p>SKA-31 (Naphtho[1,2-d]thiazol-2-ylamine) is an activator of KCa3.1 and KCa2 channels (EC50s: 260, 2900, 2900 nM for KCa3.1, KCa2.1 and KCa2.2 respectively).</p>Formula:C11H8N2SPurity:99.38%Color and Shape:SolidMolecular weight:200.26Efonidipine hydrochloride
CAS:<p>Efonidipine HCl (NZ-105) blocks T-type/L-type calcium channels; used in hypertension treatment.</p>Formula:C34H39ClN3O7PColor and Shape:SolidMolecular weight:668.12Trofinetide
CAS:<p>Trofinetide (NNZ-2566) is a synthetic analog of the endogenous N-terminus tripeptide. It has been shown to be neuroprotective in animal models of brain injury.</p>Formula:C13H21N3O6Purity:98.70% - 99.50%Color and Shape:SolidMolecular weight:315.32Nav1.8-IN-1
CAS:<p>Nav1.8-IN-1 (CHEMBL1270208) is an inhibitor of human NaV1.8</p>Formula:C20H15ClF3N3O2Purity:97.59%Color and Shape:SolidMolecular weight:421.86-(4-Methoxyphenyl)-3-pyridazinamine
CAS:<p>6-(4-Methoxyphenyl)-3-pyridazinamine is a GABAA receptor antagonist</p>Formula:C11H11N3OPurity:99.03%Color and Shape:SolidMolecular weight:201.22Tulrampator
CAS:<p>Tulrampator (S-47445) is an orally bioavailable positive AMPAR with antidepressant effects.</p>Formula:C20H17FN4O3Purity:99.77%Color and Shape:SolidMolecular weight:380.37Acetoxyvalerensre
CAS:<p>Acetoxyvalerensre (acetylvalerenolic acid) (acetylvalerenolic acid) is a derivative of valerenic acid, which is a a GABAA receptor modulator.</p>Formula:C17H24O4Purity:98.22%Color and Shape:SolidMolecular weight:292.37MK6-83
CAS:<p>MK6-83 is the transient receptor potential channel ML3 agonist.</p>Formula:C16H20N2O2S2Purity:99.5%Color and Shape:SolidMolecular weight:336.47Vonoprazan fumarate
CAS:<p>Vonoprazan fumarate (TAK-438) is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase.</p>Formula:C17H16FN3O2S·C4H4O4Purity:99.16% - 99.98%Color and Shape:SolidMolecular weight:461.46(R)-baclofen
CAS:<p>(R)-baclofen (STX209), a derivative of gamma-aminobutyric acid, is commonly utilized for the treatment of spasticity.</p>Formula:C10H12ClNO2Purity:97.20% - 98.94%Color and Shape:SolidMolecular weight:213.66CL 218872
CAS:<p>CL 218872: selective α1 GABAA receptor agonist, anxiolytic, and anticonvulsant; Ki=130 nM for α1, less potent for α2-α6.</p>Formula:C13H9F3N4Purity:99.92%Color and Shape:SolidMolecular weight:278.23
