Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(93 products)
- Adiponectin receptor(5 products)
- CFTR(64 products)
- CGRP Receptor(52 products)
- Calcium Channel(496 products)
- Chloride channel(49 products)
- GABA Receptor(336 products)
- Monoamine Transporter(23 products)
- Monocarboxylate transporter(17 products)
- NKCC(2 products)
- NPC1L1(3 products)
- Na-K-Cl cotransporter(8 products)
- OAT(27 products)
- OCT(7 products)
- P-gp(53 products)
- Potassium Channel(277 products)
- Proton pump(39 products)
- SGLT(30 products)
- Sodium Channel(202 products)
- TRP/TRPV Channel(93 products)
Show 13 more subcategories
Found 2290 products of "Membrane Transporter/Ion Channel"
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AMP-PNP tetralithium
CAS:<p>AMP analog that blocks Kir6 channels, inhibits axonal transport, and stabilizes organelle-microtubule interactions.</p>Formula:C10H13Li4N6O12P3Color and Shape:SolidMolecular weight:529.93ML67-33
CAS:<p>ML67-33 selectively activates K2P channels; EC50: 36.3 μM (cell-free), 9.7 μM (HEK293). Reversible TREK-1 modulation.</p>Formula:C18H17Cl2N5Purity:98%Color and Shape:SolidMolecular weight:374.27Pregabalin arenacarbil
CAS:<p>Pregabalin arenacarbil is a gabamimetic.</p>Formula:C15H27NO6Color and Shape:SolidMolecular weight:317.38Alilusem
CAS:<p>Alilusem is a new diuretic that is beneficial to the clinical treatment of hypertension.</p>Formula:C17H15ClKN2O5SColor and Shape:SolidMolecular weight:433.92TRPV antagonist 1
CAS:<p>TRPV antagonist 1 is an antagonist of transient receptor potential vanilloid (TRPV; IC50 < 250 nM).</p>Formula:C26H21F3N2O4SPurity:98%Color and Shape:SolidMolecular weight:514.52URAT1 inhibitor 4
CAS:<p>URAT1 inhibitor 4 is a potent, orally active Lesinurad derivative with a 7.56 μM IC50, showing greater in vivo efficacy.</p>Formula:C27H20BrN3O4S3Color and Shape:SolidMolecular weight:626.56UK-52831
CAS:<p>UK-52831, a calcium channel antagonist, is used potentially for the treatment of hypertension and myocardia ischemia.</p>Formula:C22H26Cl2N6O5Purity:98%Color and Shape:SolidMolecular weight:525.39DS2
CAS:Positive allosteric modulator of δ-subunit containing GABAA receptorsFormula:C18H12ClN3OSPurity:98%Color and Shape:SolidMolecular weight:353.83ATPA
CAS:<p>ATPA activates GluR5 glutamate receptors; EC50s range 0.66-32 μM across GluR5 variants.</p>Formula:C10H16N2O4Purity:98%Color and Shape:SolidMolecular weight:228.24Ro 19-4603
CAS:<p>Benzodiazepine inverse agonist</p>Formula:C15H17N3O3SPurity:98%Color and Shape:SolidMolecular weight:319.38CGS8216
CAS:<p>CGS8216 shows analgesic activity at high doses, has anxiolytic activity, and can be used to study immune system disorders.</p>Formula:C16H11N3OPurity:98.53%Color and Shape:SolidMolecular weight:261.28LY382884
CAS:<p>LY382884 is a selective and potent GluR5 kainate receptor antagonist with anxiolytic activity.LY382884 blocks blockade of mossy fibre LTP induction.</p>Formula:C18H23NO4Purity:98.32% - 98.71%Color and Shape:SolidMolecular weight:317.38Remacemide hydrochloride
CAS:<p>Remacemide hydrochloride is a NMDA receptor antagonist.</p>Formula:C17H21ClN2OPurity:98%Color and Shape:SolidMolecular weight:304.81NS 3763
CAS:<p>NS 3763 is a kainate receptor antagonist.</p>Formula:C22H16N2O6Purity:98%Color and Shape:SolidMolecular weight:404.37Traxoprodil Mesylate
CAS:<p>Traxoprodil Mesylate is a potent noncompetitive N-methyl-D-aspartate (NMDA) receptors antagonist and has selective for the NR2B subunit.</p>Formula:C21H29NO6SPurity:98%Color and Shape:SolidMolecular weight:423.525,7-Dichlorokynurenic acid sodium salt
CAS:<p>5,7-Dichlorokynurenic acid sodium salt is a NMDA receptor antagonist.</p>Formula:C10H5Cl2NNaO3Purity:98%Color and Shape:SolidMolecular weight:281.05F15845
CAS:<p>F 15845: potent sodium current blocker, anti-ischemic, offers short/long-term post-infarction cardioprotection.</p>Formula:C20H25NO2S2Color and Shape:SolidMolecular weight:375.55TRPC6-IN-1
CAS:<p>TRPC6-IN-1 is an inhibitor of the Transient Receptor Potential Canonical 6 Channel (TRPC6) (EC50: 4.66 μM).</p>Formula:C21H23FN4O3Purity:98%Color and Shape:SolidMolecular weight:398.43GV-196771A
CAS:<p>GV-196771A A novel NMDA receptor glycine site antagonist with potent antinociceptive activity.</p>Formula:C20H13Cl2N2NaO3Purity:96.43%Color and Shape:SolidMolecular weight:423.23AMG-628
CAS:<p>AMG-628 inhibits RAF kinase, halts growth, and triggers apoptosis in B-RAFV600E mutant colon/melanoma cells.</p>Formula:C25H25FN6O2SColor and Shape:SolidMolecular weight:492.57Ethacrynate Sodium
CAS:<p>Ethacrynate Sodium, a sodium salt, blocks chloride, potassium, and sodium transport mainly in Henle's loop.</p>Formula:C13H12Cl2NaO4Purity:98%Color and Shape:SolidMolecular weight:326.12Y-26763
CAS:Y-26763 is a K+ channel opener and active metabolite of Y-27152. This is an ATP-sensitive K+ (KATP) channel activator.Formula:C14H16N2O4Purity:98%Color and Shape:SolidMolecular weight:276.29FCPT
CAS:FCPT is an ATP competitive kinesin-5 inhibitor.Formula:C17H13FN2SPurity:98%Color and Shape:SolidMolecular weight:296.36BHF-177
CAS:<p>BHF-177 is a positive allosteric modulator of the GABAB receptor. BHF-177 reduces self-administration of nicotine in animal studies.</p>Formula:C19H20F3N3Color and Shape:SolidMolecular weight:347.38SKF 97541
CAS:<p>GABAB agonist</p>Formula:C4H12NO2PPurity:98%Color and Shape:SolidMolecular weight:137.12Galicaftor
CAS:<p>ABBV-2222 is a CFTR corrector which is studied for the treatment of cystic fibrosis (CF).</p>Formula:C28H21F4NO7Purity:98%Color and Shape:SolidMolecular weight:559.46UBP-282
CAS:AMPA and kainate receptor antagonistFormula:C15H15N3O6Purity:98%Color and Shape:SolidMolecular weight:333.3Norverapamil
CAS:<p>Norverapamil is a blocker of L-type calcium channel and an inhibitor of P-glycoprotein (P-gp) function .</p>Formula:C26H36N2O4Purity:98%Color and Shape:SolidMolecular weight:440.58JNJ-39729209
CAS:<p>JNJ-39729209 is a TRPV1 antagonist.</p>Formula:C19H11Cl2F3N4SColor and Shape:SolidMolecular weight:455.28Zonampanel
CAS:<p>Zonampanel is a selective glutamate receptor subtype, α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor antagonist.</p>Formula:C13H9N5O6Purity:98%Color and Shape:SolidMolecular weight:331.24mGAT3/4-IN-1
CAS:<p>mGAT3/4-IN-1 inhibits mGAT3/4 with pIC50: 5.31/5.24, reduces neuropathic pain in diabetic mice.</p>Formula:C26H31ClN2O2S2Color and Shape:SolidMolecular weight:503.1217-PA
CAS:17-PA is a GABAA receptor antagonist.Formula:C25H34OPurity:98%Color and Shape:SolidMolecular weight:350.54MK-0343
CAS:<p>MK0343 is an orally bioavailable GABAA receptor subtype-selective partial agonist and is a non-sedating anxiolytic.</p>Formula:C19H17F2N7OPurity:98%Color and Shape:SolidMolecular weight:397.38Sematilide
CAS:<p>Sematilide is a blocker of selective IKr channel.</p>Formula:C14H23N3O3SPurity:98%Color and Shape:SolidMolecular weight:313.42Posenacaftor
CAS:<p>Posenacaftor (PTI-801) regulates CFTR protein for cystic fibrosis research.</p>Formula:C27H27NO5Color and Shape:SolidMolecular weight:445.51Cavα2δ1&NET-IN-1
CAS:<p>Cavα2δ1&NET-IN-1 .</p>Formula:C23H26N4O2SColor and Shape:SolidMolecular weight:422.54CGS 20625
CAS:<p>partial agonist for the benzodiazepine binding site of the GABAA receptor</p>Formula:C18H19N3O2Purity:99.61%Color and Shape:SolidMolecular weight:309.36CXL-1020
CAS:<p>CXL-1020, a HNO prodrug, enhances heart muscle function & relaxation, aiding in heart failure research.</p>Formula:C7H9NO5S2Color and Shape:SolidMolecular weight:251.282-Hydroxysaclofen
CAS:2-Hydroxysaclofen is a GABAB receptor antagonist.Formula:C9H12ClNO4SPurity:98%Color and Shape:White SolidMolecular weight:265.71AMG9090
CAS:<p>AMG9090 is a transient receptor potential ankyrin 1 (TRPA1) antagonist.</p>Formula:C15H11Cl4NOSPurity:98%Color and Shape:SolidMolecular weight:395.13CGP 7930
CAS:<p>Positive allosteric modulator of GABAB receptors</p>Formula:C19H32O2Purity:98%Color and Shape:SolidMolecular weight:292.46Perzinfotel
CAS:<p>Perzinfotel, a neuroprotective NMDA antagonist with high affinity (IC50=30 nM), is selective and competitive.</p>Formula:C9H13N2O5PColor and Shape:SolidMolecular weight:260.18Ro15-4513
CAS:<p>Ro15-4513 is imidazobenzodiazepinone derivative and is a partial inverse agonist of benzodiazepine receptors. Ro15-4513 is an effective ethanol antagonist.</p>Formula:C15H14N6O3Purity:98%Color and Shape:SolidMolecular weight:326.31Alaproclate, (S)-
CAS:<p>Alaproclate, (S)- is a selective inhibitor of serotonin reuptake.</p>Formula:C13H18ClNO2Purity:98%Color and Shape:SolidMolecular weight:255.74S-8921
CAS:<p>S-8921 is an inhibitor of ileal Na+/bile acid cotransporter.</p>Formula:C30H36O9Purity:98%Color and Shape:SolidMolecular weight:540.65'-Iodoresiniferatoxin
CAS:<p>TRPV1 (VR1) receptor antagonist</p>Formula:C37H39IO9Purity:98%Color and Shape:SolidMolecular weight:754.6TPA-023B
CAS:TPA-023B: oral GABAA α2/α3 agonist (Kis: 0.73/2 nM), α1 antagonist (Ki: 1.8 nM), non-sedating anxiolytic.Formula:C21H15F2N5OPurity:98%Color and Shape:SolidMolecular weight:391.37P-gp inhibitor 5
CAS:<p>P-gp inhibitor 5 strongly blocks P-glycoprotein, enhances drug sensitivity, and reverses cancer cell drug resistance.</p>Formula:C28H20ClNO5SColor and Shape:SolidMolecular weight:517.98U-101017
CAS:<p>U-101017 is a partial benzodiazepine receptor and GABAA receptor agonist.</p>Formula:C23H27ClN4O3Purity:98%Color and Shape:SolidMolecular weight:442.94Posenacaftor sodium
CAS:<p>Posenacaftor (PTI-801) sodium, a CFTR modulator for CF research, corrects CFTR protein folding and trafficking.</p>Formula:C27H27NNaO5Color and Shape:SolidMolecular weight:468.505Org 20599
CAS:<p>GABAA receptor agonist</p>Formula:C25H40ClNO3Purity:98%Color and Shape:SolidMolecular weight:438.04NC 1100
CAS:<p>NC 1100 is a calcium channel antagonist.</p>Formula:C27H34Cl2N2O3Purity:98%Color and Shape:SolidMolecular weight:505.48CNS-5161
CAS:CNS-5161 is an NMDA antagonist.Formula:C16H18ClN3S2Purity:98%Color and Shape:SolidMolecular weight:351.92RS 30026
CAS:<p>RS 30026 is a potent calcium channel agonist.</p>Formula:C23H21NO4SColor and Shape:SolidMolecular weight:407.48(S)-Propafenone
CAS:<p>(S)-Propafenone, or (S)-SA-79, is an S-enantiomer with beta-blocking effects and sodium channel blocking class 1 antiarrhythmic properties.</p>Formula:C21H27NO3Purity:98%Color and Shape:SolidMolecular weight:341.44GYKI-52466
CAS:<p>GYKI-52466: non-competitive AMPA antagonist, IC50: 10-20 μM for AMPA. Also relaxes muscles, treats seizures, neuroprotects, reduces anxiety.</p>Formula:C17H15N3O2Purity:98%Color and Shape:SolidMolecular weight:293.32Taplucainium chloride
CAS:<p>Taplucainium chloride is a sodium channel blocker with applications as a pain reliever.</p>Formula:C23H31ClN2OColor and Shape:SolidMolecular weight:386.96SX-3228
CAS:SX-3228 is a selective agonist of benzodiazepine1 (BZ1) receptor(IC50 of 17 nM).Formula:C18H18N4O3Purity:98%Color and Shape:SolidMolecular weight:338.36GX-936
CAS:<p>GX-936, a Nav1.7 inhibitor, inhibits Nav1.7 through a voltage-sensor trapping mechanism, likely by stabilizing inactivated states of the channel.</p>Formula:C24H20F3N7O3S2Purity:98%Color and Shape:SolidMolecular weight:575.59LY 97241
CAS:<p>LY 97241 is an inhibitor of hEAG1 and hERG1 potassium channel.</p>Formula:C19H32N2O2Color and Shape:SolidMolecular weight:320.47RPR104632
CAS:RPR104632 is a novel and potent antagonist located at the NMDA glycine site with neuroprotective activity.Formula:C15H11BrCl2N2O4SPurity:99.06%Color and Shape:SolidMolecular weight:466.13ITH-12575
CAS:<p>ITH-12575 is an inhibitor of Mitochondrial Na+/Ca2+ exchange (mNCX). ITH12575 reduces Ca(2+) influx through CALHM1 at low micromolar concentrations.</p>Formula:C18H18ClNOSColor and Shape:SolidMolecular weight:331.86ML218 hydrochloride
CAS:<p>ML218 hydrochloride inhibits T-type Ca2+ channels Cav3.1-3.3; most effective on Cav3.2 and Cav3.3 (IC50s: 310 nM, 270 nM).</p>Formula:C19H27Cl3N2OPurity:98%Color and Shape:SolidMolecular weight:405.79N-Methyl Duloxetine hydrochloride
CAS:<p>N-Methyl Duloxetine hydrochloride elicits both tonic and use-dependent block of neuronal Na+ channels. N-Methyl Duloxetine hydrochloride is an analgesic.</p>Formula:C19H22ClNOSPurity:98%Color and Shape:SolidMolecular weight:347.9Cyprodenate
CAS:<p>Cyprodenate (Actebral) is a potent orally active brain-activating agent with appetite-suppressing properties, useful in studying metabolic.</p>Formula:C13H25NO2Color and Shape:SolidMolecular weight:227.34AZSMO-23
CAS:<p>AZSMO-23 activates hERG K+ channels; blocks hKv4.3-hKChIP2.2, hCav3.2, hKv1.5; activates hCav1.2/β2/α2δ.</p>Formula:C19H13ClN4OPurity:98%Color and Shape:SolidMolecular weight:348.79Halofantrine
CAS:<p>Halofantrine: antimalarial, lipophilic, blocks HERG K+ channels, targets Chloroquine-resistant P. falciparum.</p>Formula:C26H30Cl2F3NOColor and Shape:SolidMolecular weight:500.42Diltiazem malate
CAS:<p>Diltiazem malate is an ACE inhibitor and non-dihydropyridine calcium channel blocker used in the treatment of hypertension.</p>Formula:C26H32N2O9SColor and Shape:SolidMolecular weight:548.60(R)-Amlodipine
CAS:<p>(R)-Amlodipine is the R-enantiomer of Amlodipine and functions as an orally active dihydropyridine calcium channel blocker with antianginal properties.</p>Formula:C20H25ClN2O5Purity:99.977%Color and Shape:SolidMolecular weight:408.88U-7524
CAS:<p>U-7524 (AOAA), an inhibitor of GABA-T and other PLP-dependent enzymes, disrupts the Schiff base linkage, forming oxime complexes.</p>Formula:C2H5NO3Color and Shape:SolidMolecular weight:91.073-Methyl-GABA
CAS:<p>3-Methyl-GABA activates GABA aminotransferase, fits GABAaR, stimulates GAD, and acts as an anticonvulsant.</p>Formula:C20H30N2O10S2Purity:98%Color and Shape:SolidMolecular weight:522.59Ethyl dirazepate
CAS:Ethyl dirazepate has anxiolytic and hypnotic and possibly other characteristic benzodiazepine properties,is a drug which is a benzodiazepine derivative.Formula:C18H14Cl2N2O3Purity:98%Color and Shape:SolidMolecular weight:377.22UBP301
CAS:<p>UBP301 is a kainate receptor antagonist.</p>Formula:C15H14IN3O6Purity:98%Color and Shape:SolidMolecular weight:459.19Felbamate hydrate
CAS:<p>Felbamate hydrate is an effective nonsedative anticonvulsant. It is a clinical effect that may be related to the inhibition of N-methyl-D-aspartate.</p>Formula:C11H16N2O5Purity:98%Color and Shape:SolidMolecular weight:256.26Arbaclofen placarbil
CAS:<p>Arbaclofen placarbil is a GABA(B) receptor agonist with better ADMET than R-baclofen, reducing postprandial reflux in GERD.</p>Formula:C19H26ClNO6Color and Shape:SolidMolecular weight:399.87Carburazepam
CAS:<p>Carburazepam is a derivate of benzodiazepines. Benzodiazepines are a class of psychoactive drugs.</p>Formula:C17H16ClN3O2Purity:98%Color and Shape:SolidMolecular weight:329.78Cibenzoline
CAS:Cibenzoline: antiarrhythmic, blocks KATP channels, minimizes LVPG, useful in hypertrophic cardiomyopathy studies.Formula:C18H18N2Color and Shape:SolidMolecular weight:262.35URAT1&XO inhibitor 2
CAS:<p>Compound BDEO (URAT1&XO inhibitor 2) serves as a dual-action inhibitor targeting both xanthine oxidase (XO) and URAT1, demonstrating an IC50 value of 3.3 μM for</p>Formula:C14H12BrNO3Purity:98%Color and Shape:SolidMolecular weight:322.15TCS 1105
CAS:<p>TCS 1105 is a GABAA BZR ligand, blocking Sema3A and altering mouse anxiety, aggression, and social dominance.</p>Formula:C17H13FN2O2Purity:99.75%Color and Shape:SolidMolecular weight:296.3(R)-CPP
CAS:<p>(R)-CPP is a NMDA antagonist.</p>Formula:C8H17N2O5PPurity:98%Color and Shape:SolidMolecular weight:252.2PD-151307
CAS:PD-151307 is used as an N-type calcium channel blocker.Formula:C33H47N3O5Purity:98%Color and Shape:SolidMolecular weight:565.74SN05
CAS:<p>SN05 inhibits AAT with Ki: ASCT1 (2.77μM), rASCT2 (0.73μM), hASCT2 (0.87μM), EAAT1-5 (3.7-7.25μM); used in cancer research.</p>Formula:C18H17NO4Color and Shape:SolidMolecular weight:311.33RU 33965
CAS:<p>RU 33965, a 3-cyclopropyl carbonyl imidazobenzodiazepine, act as a low-efficacy benzodiazepine receptor inverse agonist.</p>Formula:C16H15N3O2Purity:98%Color and Shape:SolidMolecular weight:281.31Dihydrocapsiate
CAS:<p>Dihydrocapsiate is a compound of capsinoid family that can be used in metabolism diseas research. Dihydrocapsiate is an orally active agonist of TRPV1 [1].</p>Formula:C18H28O4Color and Shape:SolidMolecular weight:308.41BTG-1640
CAS:<p>BTG-1640 is used potentially for the treatment of anxiety and panic disorder.</p>Formula:C15H19NO2Color and Shape:SolidMolecular weight:245.32MCC-134
CAS:<p>MCC-134 is an inverse agonist for the pancreatic-type ATP-sensitive K(+) channel. It also used as a vascular relaxing agent.</p>Formula:C16H17N3OSColor and Shape:SolidMolecular weight:299.39(Rac)-MEM 1003
CAS:<p>MEM-1003, a calcium channel blocker, is used potentially for the treatment of bipolar disorders.</p>Formula:C22H25ClN2O5Color and Shape:SolidMolecular weight:432.9(S)-AMPA
CAS:<p>(S)-AMPA is an active isomer of AMPA and a selective agonist of AMPA.</p>Formula:C7H10N2O4Color and Shape:SolidMolecular weight:186.17DDO-02005 free base
CAS:<p>DDO-02005 is a potent Kv1.5 inhibitor with IC50 of 0.72μM, showing strong anti-arrhythmic and anti-AF effects in rat models.</p>Formula:C21H25N3O2Color and Shape:SolidMolecular weight:351.44NS-8
CAS:<p>NS-8, a pyrrole, activates Ca2+-sensitive K+ channels, reducing urinary frequency by inhibiting pelvic nerve activity.</p>Formula:C12H10FN3Color and Shape:SolidMolecular weight:215.23Sadopine
CAS:<p>Sadopine is a high-affinity radioligand for DHP receptor in L-type Ca2+ channels, suitable for tissue and membrane labeling.</p>Formula:C30H40F3N3O7SColor and Shape:SolidMolecular weight:643.71P2X7 receptor antagonist-2
CAS:<p>P2X7 receptor antagonist-2: potent, pIC50 6.5-7.5, reduces neuroinflammation.</p>Formula:C19H18Cl2N2O2Color and Shape:SolidMolecular weight:377.26Bts 39542
CAS:<p>Bts 39542 is a diuretic that plays a major role in the Henle circulation and increases renal blood flow without affecting glomerular filtration rate.</p>Formula:C16H11ClN4O3SColor and Shape:SolidMolecular weight:374.8UBP646
CAS:<p>UBP646 is a GluN1/GluN2 receptors potentiator.</p>Formula:C21H22O2Purity:98%Color and Shape:SolidMolecular weight:306.4NMDA receptor modulator 2
CAS:<p>NMDA receptor modulator 2 (Compound 1) is a potent modulator of the NMDA receptor that can be used for neurological disorder research [1].</p>Formula:C13H11F3N2O2Color and Shape:SolidMolecular weight:284.23NAP-1
CAS:<p>NAP-1 is an anesthetic that enhances CA1 brain inhibition in rats and causes tadpole sedation (EC50 = 0.53 μM).</p>Formula:C20H18ClNO2Color and Shape:SolidMolecular weight:339.82TRPC5-IN-2
CAS:<p>TRPC5-IN-2 is a potent inhibitor of TRPC5.</p>Formula:C17H14ClF3N6OColor and Shape:SolidMolecular weight:410.78CGP 39551
CAS:<p>CGP 39551 is a NMDA antagonist.</p>Formula:C8H16NO5PPurity:98%Color and Shape:White SolidMolecular weight:237.19bis(7)-Tacrine
CAS:<p>Bis(7)-tacrine dihydrochloride: dimeric AChE inhibitor; may treat Alzheimer's; blocks NMDA, antagonizes GABA A.</p>Formula:C33H42Cl2N4Color and Shape:SolidMolecular weight:565.63AS1928370
CAS:<p>AS1928370 is an antagonist of transient receptor potential vanilloid 1 (TRPV1).</p>Formula:C29H31N3O2Color and Shape:SolidMolecular weight:453.58NAB-14
CAS:<p>NAB-14: non-competitive GluN2C/D antagonist, IC50 580 nM for GluN1/2D, >800x selectivity over GluN2A/B, blood-brain-barrier penetrant.</p>Formula:C20H21N3O3Color and Shape:SolidMolecular weight:351.4Ac32Az19
CAS:<p>Ac32Az19 is a potent, non-toxic, and highly selective inhibitor of Breast Cancer Resistance Protein (BCRP), demonstrating an EC50 of 13 nM in BCRP-overexpressed</p>Formula:C37H33N3O6Color and Shape:SolidMolecular weight:615.67GABAA receptor agent 7
CAS:<p>Compound 5c, a GABAA receptor modulator with anticonvulsant properties and low neurotoxicity, is promising for epilepsy research.</p>Formula:C18H13ClN4OColor and Shape:SolidMolecular weight:336.77ZK93423
CAS:<p>ZK93423: potent benzodiazepine agonist, IC50=1nM, non-selective, Ki=4.1-6nM for α1-α5 GABAA subunits.</p>Formula:C23H22N2O4Color and Shape:SolidMolecular weight:390.43AMG-1
CAS:<p>AMG-1 inhibits CRAC channels, blocks effector T cells, not regulatory ones, and reduces EAE progression.</p>Formula:C18H9ClF5N3OColor and Shape:SolidMolecular weight:413.73Efflux inhibitor-1
CAS:<p>Efflux inhibitor-1 is a pyrazolopyrimidine efflux inhibitor.</p>Formula:C28H25N5O3Color and Shape:SolidMolecular weight:479.53(Rac)-NMDAR antagonist 1
CAS:<p>(Rac)-NMDAR antagonist 1 is a racemate of NMDAR antagonist 1. NMDAR antagonist 1 is a potent, orally active, NR2B-selective NMDAR antagonist.</p>Formula:C20H20BrN3O2Color and Shape:SolidMolecular weight:414.3P-gp inhibitor 3
<p>P-gp inhibitor 3 boosts Paclitaxel's effect by strongly reversing MDR via P-gp efflux blockade.</p>Formula:C48H67N3O6Color and Shape:SolidMolecular weight:782.06Clobutinol
CAS:<p>Clobutinol has anti-tussive effects. Clobutinol affects heart rate and blood pressure, it can be used for cough related research [1] [2] [3].</p>Formula:C14H22ClNOColor and Shape:SolidMolecular weight:255.78(R)-Posenacaftor sodium
CAS:<p>(R)-Posenacaftor sodium is a modulator for correcting cystic fibrosis protein folding.</p>Formula:C27H27NNaO5Color and Shape:SolidMolecular weight:468.505P-CAB agent 2 hydrochloride
CAS:<p>P-CAB agent 2 hydrochloride is a strong oral gastric acid secretion inhibitor with IC50 <100 nM on H+/K+ ATPase and 18.69 µM on hERG channel, non-toxic.</p>Formula:C22H26ClFN2O4SColor and Shape:SolidMolecular weight:468.97SK3 Channel-IN-1
CAS:<p>SK3 Channel-IN-1: Potent, selective SK3 modulator; inhibits MDA-MB-435 migration, low cytotoxicity.</p>Formula:C25H49NOColor and Shape:SolidMolecular weight:379.66Xininurad
CAS:<p>Xininurad (XNW3009) is a urate transporter (URAT) inhibitor.</p>Formula:C15H10Br2FN3O2Color and Shape:SolidMolecular weight:443.07MRS-1477
CAS:<p>MRS-1477 is used as a TRPV1 positive allosteric modulator (PAM).</p>Formula:C21H27NO4SPurity:98%Color and Shape:SolidMolecular weight:389.51Cgp 31358
CAS:<p>CGP 31358 is a new chemical that targets the NMDA receptor, potentially aiding in molecular pharmacology research.</p>Formula:C19H19ClN4O2Color and Shape:SolidMolecular weight:370.83(1R,2R)-ML-SI3
CAS:<p>(1R,2R)-ML-SI3 ((-)-trans-ML-SI3) is a selective TRPML1, TRPML2, and TRPML3 inhibitor for the study of neurodegenerative and cardiovascular diseases.</p>Formula:C23H31N3O3SColor and Shape:SolidMolecular weight:429.58GLPG-3221
CAS:<p>GLPG-3221, a potent oral CFTR corrector for cystic fibrosis treatment, has an EC50 of 105 nM.</p>Formula:C30H37F3N2O6Purity:98%Color and Shape:SolidMolecular weight:578.62IDO1-IN-19
CAS:<p>IDO1-IN-19 (Compound 17) is a potent inhibitor of IDO1 and has potential for cancer disease research.</p>Formula:C25H22F4N2O3Color and Shape:SolidMolecular weight:474.45P2X7 receptor antagonist-3
CAS:<p>P2X7 receptor antagonist-3 is a powerful inhibitor of the P2X7 receptor, exhibiting IC50 values of 4.2 nM in humans and 6.8 nM in rats, indicating its high</p>Formula:C17H12ClF3N6OColor and Shape:SolidMolecular weight:408.77FFN200 dihydrochloride
CAS:<p>FFN200 is a vesicular monoamine transporter 2 (VMAT2) substrate that selectively traces monoamine exocytosis in both neuronal cell culture and brain tissue.</p>Formula:C11H14Cl2N2O2Color and Shape:SolidMolecular weight:277.15Ivabradine
CAS:<p>Ivabradine: oral HCN blocker, lowers heart rate without affecting blood pressure, has anticonvulsant and anti-anginal properties.</p>Formula:C27H36N2O5Color and Shape:SolidMolecular weight:468.59SN40
CAS:<p>SN40: AAT inhibitor for cancer research; inhibits hASCT1 (7.29 μM), rASCT2 (2.42 μM), hASCT2 (2.94 μM), EAAT1/EAAC1/EAAT5 (5.55 μM), EAAT2 (24.43 μM).</p>Formula:C18H20N2O2Color and Shape:SolidMolecular weight:296.36Cl-HIBO
CAS:<p>desensitising AMPA receptor agonist</p>Formula:C6H7ClN2O4Purity:98%Color and Shape:SolidMolecular weight:206.58NHE3-IN-2
CAS:<p>NHE3-IN-2 is an inhibitor of NHE3 (Na+/H+ exchanger-3), applicable for treating hypertension, thrombosis, and ischaemic diseases.</p>Formula:C15H12ClN5Color and Shape:SolidMolecular weight:297.74Irampanel
CAS:<p>Irampanel is a neuroprotectant and anticonvulsant.</p>Formula:C18H19N3O2Color and Shape:SolidMolecular weight:309.36GYKI 52466 HCl
CAS:<p>GYKI 52466 is an AMPA antagonist with IC50 of 7.5 µM, also blocking kainate currents (IC50 11 µM) and reduces EPSCs and seizures in rats.</p>Formula:C17H16ClN3O2Color and Shape:SolidMolecular weight:329.784Nemadipine-A
CAS:<p>Nemadipine A blocks L-type Ca2+ channels, alters C. elegans morphology, boosts TRAIL's cancer kill rate, and lowers Survivin in A549 cells.</p>Formula:C19H18F5NO4Color and Shape:SolidMolecular weight:419.34KR 60436
CAS:<p>KR 60436 is an inhibitor of potassium hydrogen ATPase.</p>Formula:C22H22F3N3O3Color and Shape:SolidMolecular weight:433.42Zoniporide dihydrochloride
CAS:<p>Sodium-hydrogen exchanger isoform 1 (NHE1) inhibitor</p>Formula:C17H18Cl2N6OPurity:98%Color and Shape:SolidMolecular weight:393.27(R)-Olacaftor
CAS:<p>(R)-Olacaftor (VX-440) is a CFTR modulator with promise for researching cystic fibrosis.</p>Formula:C29H34FN3O4SColor and Shape:SolidMolecular weight:539.66A1899
CAS:<p>A1899 is a effective and selective TASK-1 and TASK-3 antagonist.</p>Formula:C30H26F2N2O3Purity:98%Color and Shape:SolidMolecular weight:500.54JNJ-54166060
CAS:<p>JNJ-54166060 is a potent and selective antagonist of P2X7 receptor, with IC 50 s of 4/115/72 nM for human/rat/mouse P2X7 receptor, respectively [1].</p>Formula:C20H15ClF4N4OColor and Shape:SolidMolecular weight:438.81L-AP5
CAS:<p>L-AP5 is a NMDA antagonist.</p>Formula:C5H12NO5PPurity:98%Color and Shape:SolidMolecular weight:197.13UMB68 sodium
CAS:<p>UMB-68 is a GHB receptor ligand with no affinity (IC(50) >100 microM) at GABA(A) or GABA(B) receptors.</p>Formula:C6H12NaO3Color and Shape:SolidMolecular weight:155.149Cgp 55802A
CAS:<p>CGP 55802A is a novel photoaffinity ligand for in-situ labeling of NMDA receptors.</p>Formula:C18H24IN5NaO7PColor and Shape:SolidMolecular weight:603.286PPPA
CAS:<p>PPPA is a NMDA receptor antagonist.</p>Formula:C9H18NO5PPurity:98%Color and Shape:SolidMolecular weight:251.22PA1 2HCl
CAS:<p>PA1 2HCl is a blocker of photoswitchable epithelial sodium channel (ENaC).</p>Formula:C18H16ClN9OColor and Shape:SolidMolecular weight:409.83Lercanidipine. (R)-
CAS:<p>(R)-Lercanidipine enantiomer: antihypertensive, blocks L-type Ca2+ channels, dilates blood vessels.</p>Formula:C36H41N3O6Color and Shape:SolidMolecular weight:611.73OptoBI-1
CAS:<p>OptoBI-1 是一种光敏分子，是光致变色的TRPC3激动剂，可用作控制神经元放电的光药理学工具。</p>Formula:C32H37N5O2Color and Shape:SoildMolecular weight:523.674,9-Anhydrotetrodotoxin
CAS:<p>4,9-anhydro-TTX blocks Nav1.6 channels (IC50=7.8 nM); has varying IC50 for Nav1.2-Nav1.8.</p>Formula:C11H15N3O7Color and Shape:SolidMolecular weight:301.25RA-2
CAS:<p>RA-2 is a pan-negative-gating modulator of KCa2/3 channels that acts by inhibiting EDH-type relaxation in coronary arteries.</p>Formula:C22H16F2O6Color and Shape:SolidMolecular weight:414.36Procyclidine
CAS:<p>Procyclidine is an anticholinergic, muscarinic and NMDA antagonist used in Parkinson's and psychiatric disorder studies.</p>Formula:C19H29NOColor and Shape:SolidMolecular weight:287.44TMB 8 (hydrochloride)
CAS:<p>TMB 8 blocks nAChRs (IC50: 390-480 nM), reduces Ca2+ in muscles, hinders rabbit aorta contraction at 50 μM, and inhibits PKC dose-dependently.</p>Formula:C22H38ClNO5Color and Shape:White SolidMolecular weight:431.99Etbicyphat
CAS:<p>Etbicyphat: potent GABA(A) antagonist, induces epileptiform activity, binds to GABA/benzodiazepine receptors.</p>Formula:C6H11O4PColor and Shape:SolidMolecular weight:178.12CGP-78608
CAS:<p>CGP-78608 is a glycine site-specific N-methyl-D-aspartate receptor antagonist prevents activation of the NMDA/NO/CGMP pathway by ammonia.</p>Formula:C11H13BrN3O5PColor and Shape:SolidMolecular weight:378.12TTT-28
CAS:<p>TTT-28, a thiazole-valine peptidomimetic, selectively inhibits ABCB1 to reverse MDR with low toxicity.</p>Formula:C31H31N3O6SPurity:98%Color and Shape:SolidMolecular weight:573.66Radequinil
CAS:<p>Radequinil is a benzodiazepine receptor partial inverse agonist. Rade quinil binds to GABA(-) and GABA(+) ligand (Kis: 5.15 and 6.11 nM, respectively).</p>Formula:C18H14N4O3Purity:98%Color and Shape:SolidMolecular weight:334.33PF-06649298
CAS:<p>PF-06649298 inhibits NaCT, blocking citrate transport in hepatocytes, IC50: 16.2 μM, affects glucose and lipid metabolism.</p>Formula:C16H22O5Color and Shape:SolidMolecular weight:294.34P2X3 antagonist 36
CAS:<p>P2X3 antagonist 36 is a P2X3 antagonist.</p>Formula:C20H18ClF3N6O3Color and Shape:SolidMolecular weight:482.84UBP618
CAS:<p>UBP618 is a GluN1/GluN2 receptors pan-inhibitor.</p>Formula:C17H11BrO3Purity:98%Color and Shape:SolidMolecular weight:343.17LY 233053
CAS:<p>LY 233053 is a Competitive NMDA receptor antagonist.</p>Formula:C8H13N5O2Purity:98%Color and Shape:SolidMolecular weight:211.22GS-462808
CAS:<p>GS-462808: Cardiac Nav1.5 inhibitor, less brain penetration/activity.</p>Formula:C17H12F3N5O3Color and Shape:SolidMolecular weight:391.3Pipazethate
CAS:<p>Pipipyrazine is a nonnarcotic oral cough suppressant, cough suppressant.</p>Formula:C21H25N3O3SColor and Shape:SolidMolecular weight:399.51Cavα2δ1&NET-IN-2
CAS:<p>Cavα2δ1&NET-IN-2 .</p>Formula:C22H26N6O2SColor and Shape:SolidMolecular weight:438.55Bliretrigine
CAS:<p>Bliretrigine, a sodium channel blocker, effectively relieves pain [1] [2] [3].</p>Formula:C20H24N4O2Color and Shape:SolidMolecular weight:352.43AJG-049 HCl
CAS:<p>AJG-049 HCl is a calcium channel antagonist that inhibits L-type Ca2+ channels via diltiazem-binding site(s).</p>Formula:C27H31ClN2O2Color and Shape:SolidMolecular weight:451.01NNC052090
CAS:<p>NNC052090 inhibits GABA uptake, favoring hBGT-1 (Ki=1.4μM), affects α1/D2 receptors (IC50=266/1632nM).</p>Formula:C27H30N2O2Color and Shape:SolidMolecular weight:414.54A 784168
CAS:<p>A-784168: potent, oral TRPV1 inhibitor with good CNS penetration.</p>Formula:C19H15F6N3O3SColor and Shape:SolidMolecular weight:479.4Arachidonyl serotonin
CAS:<p>Dual FAAH inhibitor/TRPV1 antagonist</p>Formula:C30H42N2O2Purity:98%Color and Shape:SolidMolecular weight:462.67P-CAB agent 1
CAS:<p>Compound B19, a P-CAB, inhibits H+/K+-ATPase with IC50 of 60.50 nM, useful in ARD research.</p>Formula:C26H23FN4OColor and Shape:SolidMolecular weight:426.49UR-MB108
CAS:<p>UR-MB108 is a potent and selective inhibitor of ABCG2 (BCRP), displaying an IC50 value of 79 nM, and exhibits stability in blood plasma.</p>Formula:C40H38N6O4Color and Shape:SolidMolecular weight:666.77Cariporide Mesylate
CAS:<p>Cariporide Mesylate is a selective inhibitor of the Na+/H+ exchanger isoform 1.</p>Formula:C13H21N3O6S2Color and Shape:SolidMolecular weight:379.45U89232
CAS:<p>U-89232 is an opener of the cardioselective KATP channel.</p>Formula:C19H25N5O2Purity:98%Color and Shape:SolidMolecular weight:355.43TC-P 262
CAS:<p>P2X3 and P2X2/3 receptor antagonist</p>Formula:C14H18N4OPurity:98%Color and Shape:SolidMolecular weight:258.32Azimilide
CAS:<p>class III anti-arrhythmic drug</p>Formula:C23H28ClN5O3Purity:98%Color and Shape:SolidMolecular weight:457.95DDO-02001
CAS:<p>DDO-02001 can be used in anti-arrhythmia research. DDO-02001 is a moderately potent inhibitor of Kv1.5 potassium channel with an IC50 value of 17.7 μM [1].</p>Formula:C20H24N2O2Color and Shape:SolidMolecular weight:324.42ASIC-IN-1
CAS:<p>ASIC-IN-1 is a potent inhibitor of acid-sensing ion channels, demonstrating an IC 50 value of less than 10 μM.</p>Formula:C23H25N3O2Color and Shape:SolidMolecular weight:375.46Becampanel
CAS:<p>Becampanel (AMP397) is the first competitive AMPA antagonist. Becampanel (AMP397) also is an antiepileptic agent.</p>Formula:C10H11N4O7PPurity:98%Color and Shape:SolidMolecular weight:330.19MRK-623
CAS:<p>MRK-623 (14k) is an oral GABA A agonist with high affinity for α1/α2/α3/α5 subunits and anxiolytic properties.</p>Formula:C20H17FN4OColor and Shape:SolidMolecular weight:348.37CAY10608
CAS:<p>CAY10608 selectively blocks NR2B NMDA receptors (IC50 = 50 nM), is neuroprotective, and reduces brain infarct size in ischemia.</p>Formula:C18H22Cl2N2O4SColor and Shape:SolidMolecular weight:433.356'-Iodoresiniferatoxin
CAS:<p>TRPV1 (VR1) vanilloid receptor partial agonist</p>Formula:C37H39IO9Purity:98%Color and Shape:SolidMolecular weight:754.6LUF7244
CAS:<p>LUF7244 is a K v 11.1 channel modulator with anti-arrhythmia research potential, curbing early afterdepolarizations.</p>Formula:C20H15ClN2O3Color and Shape:SolidMolecular weight:366.8PMPA (NMDA antagonist)
CAS:<p>PMPA (NMDA antagonist) is a Competitive NMDA receptor antagonist.</p>Formula:C6H13N2O5PPurity:98%Color and Shape:SolidMolecular weight:224.15piCRAC-1
CAS:<p>piCRAC-1 is a powerful inhibitor of the photoinducible Ca2+ release-activated Ca2+ (CRAC) channel.</p>Formula:C17H10F6N4Color and Shape:SolidMolecular weight:384.28RyRs activator 3
CAS:<p>RyRs activator 3 (compound A4) serves as an insecticide highly effective against both the diamondback moths, M.</p>Formula:C23H19BrCl2N6O3Purity:98%Color and Shape:SolidMolecular weight:578.25Ned-K
CAS:<p>Ned-K blocks NAADP, reduces heart ischemia-reperfusion calcium waves.</p>Formula:C31H31N5O3Color and Shape:SolidMolecular weight:521.61Relutrigine
CAS:<p>Relutrigine (PRAX-562) is an oral persistent sodium channel inhibitor with anticonvulsant properties, IC50 of 141 nM/75 nM for ATX-II/SCN8A-N1768D.</p>Formula:C15H11F6N5O2Color and Shape:SolidMolecular weight:407.27(R)-(+)-HA-966
CAS:<p>(R)-(+)-HA-966 ((+)-HA-966) is a partial agonist/antagonist of glycine site of the N-methyl-D-aspartate (NMDA) receptor complex. (R)-(+)-HA-966 selectively blocks the activation of the mesolimbic dopamine system by amphetamine, has the potential for neuro</p>Formula:C4H8N2O2Color and Shape:White SolidMolecular weight:116.12Otaplimastat
CAS:<p>SP-8203 is a reactive oxygen species inhibitor and superoxide dismutase stimulant.</p>Formula:C28H34N6O5Purity:98%Color and Shape:SolidMolecular weight:534.61DL-AP5 Sodium salt
CAS:DL-AP5 Sodium salt is a NMDA receptor antagonist.Formula:C5H12NNaO5PPurity:98%Color and Shape:SolidMolecular weight:220.12Linopirdine dihydrochloride
CAS:<p>KV7 (KCNQ) voltage-gated potassium channels blocker</p>Formula:C26H22ClN3OPurity:98%Color and Shape:SolidMolecular weight:427.93TDN345
CAS:<p>TDN345 is a antagonist of Ca2+, for the treatment of vascular and senile dementia including Alzheimer's disease.</p>Formula:C28H34F2N2O2Purity:98%Color and Shape:SolidMolecular weight:468.58PK-THPP
CAS:<p>PK-THPP is a channel blocker of TASK-3.</p>Formula:C29H32N4O2Color and Shape:SolidMolecular weight:468.59MPX-007
CAS:<p>MPX-007, a potent NMDA inhibitor, inhibits GluN2A-containing NMDA receptors expressed in HEK cells with IC50s of 27 nM.</p>Formula:C18H17F2N5O3S2Color and Shape:SolidMolecular weight:453.49NS5818
CAS:<p>NS5818 inhibits ClC.</p>Formula:C23H19Cl2N7O2Purity:98%Color and Shape:SolidMolecular weight:496.35P-CAB agent 2
CAS:<p>Potent P-CAB agent 2 blocks gastric acid secretion; H+/K+-ATPase IC50 <100 nM, hERG IC50 18.69 μM; non-toxic.</p>Formula:C22H25FN2O4SColor and Shape:SolidMolecular weight:432.51RS 029
CAS:<p>RS 029 is a nitroimidazole that has been exhibited to significantly inhibit (Na+K+) ATP-ase activity.</p>Formula:C13H16N6O6Purity:98%Color and Shape:SolidMolecular weight:352.3CP 339818 hydrochloride
CAS:<p>KV1.3 channel antagonist</p>Formula:C21H25ClN2Purity:98%Color and Shape:SolidMolecular weight:340.89Vincanol
CAS:<p>Vincanol is a potent voltage-gated Na+ channels blocker.</p>Formula:C19H24N2OPurity:98%Color and Shape:SolidMolecular weight:296.41NS004
CAS:<p>NS004 is a large-conductance K+ channel opener, it inhibits mitochondrial function in glioma cells.</p>Formula:C14H8ClF3N2O2Purity:98%Color and Shape:SolidMolecular weight:328.67KCa2 channel modulator 1
CAS:<p>Compound 2o, a selective K/Ca2 channel enhancer, boosts rat K Ca 2.2 (EC50: 0.99 μM) and human K Ca 2.3 (EC50: 0.19 μM).</p>Formula:C16H15ClFN5Color and Shape:SolidMolecular weight:331.78Leconotide
CAS:<p>Leconotide is a calcium channel blocker and antihyperalgesia agent; isolated from the venom of the cone snail, Conus catus.</p>Formula:C107H179N35O36S7Color and Shape:SolidMolecular weight:2756.23TTA-P2
CAS:<p>TTA-P2: potent CNS-penetrating T-type Ca2+ channel blocker; eliminates Cav3.1 window currents.</p>Formula:C21H29Cl2FN2O2Color and Shape:SolidMolecular weight:431.37NAV26
CAS:<p>NAV26 is a selective blocker of the Nav1.7 channel.</p>Formula:C22H21F3N2O4Purity:98%Color and Shape:SolidMolecular weight:434.41GABAA receptor modulator-2
CAS:<p>Compound 20: Selective, oral α5-GABAAR inhibitor, Ki: 4.1 nM. High stability, CNS safe.</p>Formula:C22H22FN3O5SColor and Shape:SolidMolecular weight:459.49ANO1-IN-2
CAS:<p>ANO1-IN-2: potent ANO1 blocker (IC50: 1.75 μM), less effective on ANO2 (IC50: 7.43 μM), inhibits glioblastoma cell growth.</p>Formula:C16H14ClN3O2S2Color and Shape:SolidMolecular weight:379.88BMS-284640
CAS:<p>BMS-284640 is a NHE inhibitor that protects against MI in animal studies.</p>Formula:C15H19N3O2Color and Shape:SolidMolecular weight:273.33Lanicemine
CAS:<p>Lanicemine is a low-trapping NMDA channel blocker. It also has a binding (Ki: 0.56-2.1 μM).</p>Formula:C13H14N2Purity:98%Color and Shape:SolidMolecular weight:198.26P2X2/3 modulator-1
CAS:<p>Compound 46, a P2X2/3 modulator, could aid in research of pain, CNS disorders, and inflammation.</p>Formula:C26H21N5OColor and Shape:SolidMolecular weight:419.48UTA1inh-C1
CAS:<p>UTA1inh-C1 is a novel inhibitor of kidney urea transporter UT-A1.</p>Formula:C22H24N6O4S2Color and Shape:SolidMolecular weight:500.59
