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Membrane Transporter/Ion Channel

Membrane Transporter/Ion Channel

Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.

Subcategories of "Membrane Transporter/Ion Channel"

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Found 2280 products of "Membrane Transporter/Ion Channel"

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  • ABCG2-IN-2

    CAS:
    <p>ABCG2-IN-2 is a potent inhibitor of ABCG2, exhibiting favorable oral pharmacokinetic profiles in mice, and is applicable for investigating tumor multidrug</p>
    Formula:C25H34N4O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:454.56
  • U-89843A

    CAS:
    <p>U-89843A is an allosteric modulator of the GABA_A receptor, known to enhance GABA-induced Cl^- currents [1].</p>
    Formula:C16H24ClN5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:321.85
  • TWIK-1/TREK-1-IN-1

    CAS:
    <p>Compound 2a, identified as TWIK-1/TREK-1-IN-1, acts as an inhibitor of the TREK-1, a two-pore domain potassium channel (K2p) that forms TREK-1 homodimers and</p>
    Formula:C21H24F3NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:395.42
  • β-CCB

    CAS:
    <p>benzodiazepine receptor ligand</p>
    Formula:C16H16N2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:268.31
  • RPR-260243

    CAS:
    <p>RPR-260243 is a novel activator of HERG and modifies HERG currents inhibited by dofetilide (IC50 = 58 nM).</p>
    Formula:C28H25F3N2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:510.5
  • (BrMT)2

    CAS:
    <p>(BrMT)2 is an activator of the Kv1.1 potassium ion channel.</p>
    Formula:C20H20Br2N4S2
    Color and Shape:Solid
    Molecular weight:540.34
  • D-3263 hydrochloride

    CAS:
    <p>D-3263 hydrochloride (D3263 HCl salt) is enteric-coated, orally bioavailable transient receptor potential melatonin member 8 (TRPM8) agonist.</p>
    Formula:C21H32ClN3O3
    Purity:99.93%
    Color and Shape:Solid
    Molecular weight:409.95
  • Vernakalant Hydrochloride

    CAS:
    <p>Vernakalant Hydrochloride (RSD1235 hydrochloride) is a mixed voltage- and frequency-dependent Na+ and atria-preferred K+ channel blocker.</p>
    Formula:C20H32ClNO4
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:385.93
  • YHO-13351 free base

    CAS:
    <p>YHO-13351 free base is the water-soluble prodrug of YHO-13177 which is an inhibitor of BCRP .</p>
    Formula:C26H33N3O4S
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:483.62
  • HN37

    CAS:
    <p>HN37, KCNQ2 activator (EC50=37 nM). Affordable Excellence: Reliable Quality You Can Trust</p>
    Formula:C20H21FN2O2
    Purity:99.27%
    Color and Shape:Solid
    Molecular weight:340.39
  • XPC-6444

    CAS:
    <p>XPC-6444 is a isoform-selective, and CNS-penetrant inhibitor of NaV1.6 with IC50 of41 nM for hNaV1.6,with anticonvulsant activity.</p>
    Formula:C22H25F3N4O2S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:498.58
  • Pinacidil

    CAS:
    <p>Pinacidil (P 1134) is a guanidine that opens potassium channels and directly dilates peripheral blood vessels in small arteries, lowering blood pressure and</p>
    Formula:C13H19N5
    Purity:99.9%
    Color and Shape:Solid
    Molecular weight:245.32
  • JTV-519 hemifumarate

    CAS:
    <p>JTV-519 hemifumarate: Ca2+ blocker, SERCA inhibitor, ryanodine receptor partial agonist; antiarrhythmic, cardioprotective.</p>
    Formula:C54H68N4O8S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:965.28
  • ML252

    CAS:
    <p>ML252 selectively inhibits KCNQ2 (IC50=69nM) and Cytochrome P450 isoforms CYP1A2, CYP2C9, CYP3A4, CYP2D6 with low nanomolar IC50s.</p>
    Formula:C20H24N2O
    Color and Shape:Solid
    Molecular weight:308.42
  • VU0405601

    CAS:
    <p>VU0405601 is a hERG channel activator that protects against drug-induced cardiac arrhythmias.</p>
    Formula:C17H13BrN2O2
    Purity:99.16%
    Color and Shape:Solid
    Molecular weight:357.2
  • JNc-440

    CAS:
    <p>JNc-440, a strong anti-hypertensive, boosts TRPV4-KCa2.3 interaction and vasodilation, lowering blood pressure in mice.</p>
    Formula:C26H24N4O3
    Color and Shape:Solid
    Molecular weight:440.49
  • GNE-5729

    CAS:
    <p>GNE-5729 is a positive allosteric modulator of NMDAR blood-brain barrier orally available, GluN2A, GluN2C and GluN2D, neurological and psychiatric disorders.</p>
    Formula:C17H10Cl2F3N5O
    Purity:99.40% - 99.85%
    Color and Shape:Solid
    Molecular weight:428.2
  • SB-237376 HCl

    CAS:
    <p>SB-237376 HCl (SB-237376 hydrochloride) is a calcium and potassium channel antagonist used in the treatment of cardiac arrhythmias.</p>
    Formula:C20H26ClN3O5
    Purity:98.70%
    Color and Shape:Solid
    Molecular weight:423.89
  • Metapramine

    CAS:
    <p>Metapramine, a tricyclic antidepressant, blocks norepinephrine reuptake and is a low-affinity NMDA antagonist.</p>
    Formula:C16H18N2
    Purity:99.03% - 99.67%
    Color and Shape:Solid
    Molecular weight:238.33
  • TRPC6-IN-2

    CAS:
    <p>TRPC6-IN-2 is a TRPC protein inhibitor, specifically inhibiting TRPC6 protein.</p>
    Formula:C19H17Cl2FN6
    Color and Shape:Solid
    Molecular weight:419.28
  • (±)-Homoproline Hydrochloride

    CAS:
    <p>(±)-Homoproline Hydrochloride. Affordable Excellence: Reliable Quality You Can Trust</p>
    Formula:C6H12ClNO2
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:165.62
  • NO 711

    CAS:
    <p>NO 711(NNC-711 free acid) is a selective inhibitor of GAT-1, which enhances non-rapid eye movement sleep, and prevents paclitaxel-induced neuropathic pain.</p>
    Formula:C21H22N2O3
    Purity:99.70%
    Color and Shape:Solid
    Molecular weight:350.41
  • Hyperforin dicyclohexylammonium salt

    CAS:
    <p>Hyperforin dicyclohexylammonium is a TRPC6 activator and antidepressant that modulates Ca2+ levels.</p>
    Formula:C47H75NO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:718.1
  • TRPV4 agonist-1

    CAS:
    <p>TRPV4 agonist-1 is an agonist of TRPV4 (EC50: 60 nM in the hTRPV4 Ca2+ assay).</p>
    Formula:C25H23ClF2N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:484.93
  • GoSlo-SR-5-69

    CAS:
    <p>BK channel activator (EC50 = 251 nM). Shifts the voltage required for half maximal negatively (DV1/2 = -104 mV).</p>
    Formula:C24H20N2NaO5S
    Color and Shape:Solid
    Molecular weight:471.48
  • PF 05089771 tosylate

    CAS:
    <p>PF-05089771 inhibits Nav1.7 channels (IC50: 11-33 nM), selective over Nav1.1-1.6/1.8, Ca+, K+ channels, TRPV1; 1000x affinity for half-inactivated state.</p>
    Formula:C18H12Cl2FN5O3S2·C7H8O3S
    Purity:98.55%
    Color and Shape:Solid
    Molecular weight:672.56
  • (R)-3C4HPG

    CAS:
    <p>NMDA and AMPA/kainate receptor antagonist</p>
    Formula:C9H9NO5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:211.17
  • PPDA

    CAS:
    <p>Subtype-selective NMDA receptor antagonist</p>
    Formula:C21H18N2O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:378.38
  • AZD 3043

    CAS:
    <p>AZD 3043 (THRX 918661) is a modulator of the gamma-aminobutyric acid type A receptor, a novel sedative-hypnotic, and a potential short-acting anesthetic.</p>
    Formula:C19H29NO5
    Purity:98.19% - 99.55%
    Color and Shape:Solid
    Molecular weight:351.44
  • PPNDS

    CAS:
    <p>P2X1 receptor antagonist</p>
    Formula:C18H15N4NaO14PS2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:629.42
  • KCa1.1 channel activator-2


    <p>KCa1.1 channel activator-2, a Quercetin hybrid, selectively stimulates vascular KCa1.1 channel, with strong myorelaxant effects.</p>
    Formula:C23H22O8S2
    Color and Shape:Solid
    Molecular weight:490.55
  • JNJ-56022486

    CAS:
    <p>JNJ-56022486 is a selective TARP γ‑8 AMPA receptor modulator.</p>
    Formula:C15H10ClN3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:283.71
  • Istaroxime

    CAS:
    <p>Istaroxime is an effective inhibitor of Na+, K+-ATPase (IC50: 0.11 μM).</p>
    Formula:C21H32N2O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:360.49
  • Lesogaberan

    CAS:
    <p>Lesogaberan: selective GABAB agonist, EC50 8.6 nM, Ki 5.1 nM in rats, weak GABAA affinity (Ki 1.4 μM).</p>
    Formula:C3H9FNO2P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:141.08
  • E 0747

    CAS:
    <p>E 0747 is an antiarrhythmic agent of class 1C type. E-0747 suppresses arrhythmia by inhibiting the Na channels of cardiac cells.</p>
    Formula:C21H28ClN3O4
    Purity:95.17%
    Color and Shape:Solid
    Molecular weight:421.92
  • SCH 50911 hydrochloride

    CAS:
    <p>SCH 50911 hydrochloride is a selective, orally-active and competitive antagonist of γ-Aminobutyric acid B GABA(B) receptor(IC50 : 1.1 μM).</p>
    Formula:C8H16ClNO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:209.67
  • NMDA receptor antagonist 4

    CAS:
    <p>NMDA antagonist 4 (IIc) is an oral, voltage-dependent blocker with IC50 of 1.93 μM and may penetrate the BBB, useful in Alzheimer's research.</p>
    Formula:C15H18FN
    Color and Shape:Solid
    Molecular weight:231.31
  • UK 78282 hydrochloride

    CAS:
    <p>UK-78282 hydrochloride, a Kv1.3 blocker.UK-78282 hydrochloride inhibits Kv1.3 voltage-gated potassium channels and suppresses human T cell activation.</p>
    Formula:C29H36ClNO2
    Purity:99.68%
    Color and Shape:Solid
    Molecular weight:466.05
  • Puliginurad

    CAS:
    <p>Puliginurad (YL-90148) is a urate transporter protein inhibitor that inhibits the reabsorption of uric acid.Puliginurad is used in the treatment of gout.</p>
    Formula:C19H16N2O2S
    Purity:99.96% - 99.96%
    Color and Shape:Solid
    Molecular weight:336.41
  • TRPV3 antagonist 74a

    CAS:
    <p>TRPV3 antagonist 74a (TRPV3 74a) is a specific TRPV3 antagonist for the study of neurological disorders.</p>
    Formula:C17H17F3N2O2
    Purity:≥98.0%
    Color and Shape:Solid
    Molecular weight:338.32
  • AVE1231

    CAS:
    <p>AVE1231 is a TASK-1 channel blocker that inhibits TASK-1 and can be used in the study of atrial fibrillation.</p>
    Formula:C20H27N3O4S
    Purity:98.03%
    Color and Shape:Solid
    Molecular weight:405.51
  • Phaclofen

    CAS:
    <p>GABAB antagonist</p>
    Formula:C9H13ClNO3P
    Purity:99.32%
    Color and Shape:White Solid
    Molecular weight:249.63
  • Apimostinel

    CAS:
    <p>Apimostinel (NRX-1074; AGN-241660) is a partial agonist of NMDA receptor.</p>
    Formula:C25H37N5O6
    Color and Shape:Solid
    Molecular weight:503.59
  • P-gp inhibitor 5

    CAS:
    <p>P-gp inhibitor 5 strongly blocks P-glycoprotein, enhances drug sensitivity, and reverses cancer cell drug resistance.</p>
    Formula:C28H20ClNO5S
    Color and Shape:Solid
    Molecular weight:517.98
  • TPA-023B

    CAS:
    <p>TPA-023B: oral GABAA α2/α3 agonist (Kis: 0.73/2 nM), α1 antagonist (Ki: 1.8 nM), non-sedating anxiolytic.</p>
    Formula:C21H15F2N5O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:391.37
  • 5'-Iodoresiniferatoxin

    CAS:
    <p>TRPV1 (VR1) receptor antagonist</p>
    Formula:C37H39IO9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:754.6
  • U-101017

    CAS:
    <p>U-101017 is a partial benzodiazepine receptor and GABAA receptor agonist.</p>
    Formula:C23H27ClN4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:442.94
  • Posenacaftor sodium

    CAS:
    <p>Posenacaftor (PTI-801) sodium, a CFTR modulator for CF research, corrects CFTR protein folding and trafficking.</p>
    Formula:C27H27NNaO5
    Color and Shape:Solid
    Molecular weight:468.505
  • Org 20599

    CAS:
    <p>GABAA receptor agonist</p>
    Formula:C25H40ClNO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:438.04
  • NC 1100

    CAS:
    <p>NC 1100 is a calcium channel antagonist.</p>
    Formula:C27H34Cl2N2O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:505.48
  • S-8921

    CAS:
    <p>S-8921 is an inhibitor of ileal Na+/bile acid cotransporter.</p>
    Formula:C30H36O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:540.6
  • CNS-5161

    CAS:
    <p>CNS-5161 is an NMDA antagonist.</p>
    Formula:C16H18ClN3S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:351.92
  • RS 30026

    CAS:
    <p>RS 30026 is a potent calcium channel agonist.</p>
    Formula:C23H21NO4S
    Color and Shape:Solid
    Molecular weight:407.48
  • GX-674

    CAS:
    <p>GX-674 is a highly potent and selective voltage-gated sodium channel 1.7 (Nav1.7) antagonist with an IC50 value of 0.1 nM measured at -40 mV for the study of</p>
    Formula:C21H13ClF2N6O3S2
    Purity:98.60%
    Color and Shape:Solid
    Molecular weight:534.95
  • (S)-Propafenone

    CAS:
    <p>(S)-Propafenone, or (S)-SA-79, is an S-enantiomer with beta-blocking effects and sodium channel blocking class 1 antiarrhythmic properties.</p>
    Formula:C21H27NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:341.44
  • GYKI-52466

    CAS:
    <p>GYKI-52466: non-competitive AMPA antagonist, IC50: 10-20 μM for AMPA. Also relaxes muscles, treats seizures, neuroprotects, reduces anxiety.</p>
    Formula:C17H15N3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:293.32
  • Taplucainium chloride

    CAS:
    <p>Taplucainium chloride is a sodium channel blocker with applications as a pain reliever.</p>
    Formula:C23H31ClN2O
    Color and Shape:Solid
    Molecular weight:386.96
  • Alaproclate, (S)-

    CAS:
    <p>Alaproclate, (S)- is a selective inhibitor of serotonin reuptake.</p>
    Formula:C13H18ClNO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:255.74
  • SX-3228

    CAS:
    SX-3228 is a selective agonist of benzodiazepine1 (BZ1) receptor(IC50 of 17 nM).
    Formula:C18H18N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:338.36
  • Ro15-4513

    CAS:
    <p>Ro15-4513 is imidazobenzodiazepinone derivative and is a partial inverse agonist of benzodiazepine receptors. Ro15-4513 is an effective ethanol antagonist.</p>
    Formula:C15H14N6O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:326.31
  • GX-936

    CAS:
    <p>GX-936, a Nav1.7 inhibitor, inhibits Nav1.7 through a voltage-sensor trapping mechanism, likely by stabilizing inactivated states of the channel.</p>
    Formula:C24H20F3N7O3S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:575.59
  • LY 97241

    CAS:
    <p>LY 97241 is an inhibitor of hEAG1 and hERG1 potassium channel.</p>
    Formula:C19H32N2O2
    Color and Shape:Solid
    Molecular weight:320.47
  • RPR104632

    CAS:
    <p>RPR104632 is a novel and potent antagonist located at the NMDA glycine site with neuroprotective activity.</p>
    Formula:C15H11BrCl2N2O4S
    Purity:99.06%
    Color and Shape:Solid
    Molecular weight:466.13
  • ITH-12575

    CAS:
    <p>ITH-12575 is an inhibitor of Mitochondrial Na+/Ca2+ exchange (mNCX). ITH12575 reduces Ca(2+) influx through CALHM1 at low micromolar concentrations.</p>
    Formula:C18H18ClNOS
    Color and Shape:Solid
    Molecular weight:331.86
  • Perzinfotel

    CAS:
    <p>Perzinfotel, a neuroprotective NMDA antagonist with high affinity (IC50=30 nM), is selective and competitive.</p>
    Formula:C9H13N2O5P
    Color and Shape:Solid
    Molecular weight:260.18
  • TTA-Q6(isomer)

    CAS:
    <p>TTA-Q6(isomer) is an isomer of TTA-Q6. TTA-Q6 is a selective antagonist of the T-type Ca2+ channel.</p>
    Formula:C20H15ClF3N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:405.8
  • ML218 hydrochloride

    CAS:
    <p>ML218 hydrochloride inhibits T-type Ca2+ channels Cav3.1-3.3; most effective on Cav3.2 and Cav3.3 (IC50s: 310 nM, 270 nM).</p>
    Formula:C19H27Cl3N2O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:405.79
  • N-Methyl Duloxetine hydrochloride

    CAS:
    <p>N-Methyl Duloxetine hydrochloride elicits both tonic and use-dependent block of neuronal Na+ channels. N-Methyl Duloxetine hydrochloride is an analgesic.</p>
    Formula:C19H22ClNOS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:347.9
  • Cyprodenate

    CAS:
    <p>Cyprodenate (Actebral) is a potent orally active brain-activating agent with appetite-suppressing properties, useful in studying metabolic.</p>
    Formula:C13H25NO2
    Color and Shape:Solid
    Molecular weight:227.34
  • CGP 7930

    CAS:
    <p>Positive allosteric modulator of GABAB receptors</p>
    Formula:C19H32O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:292.46
  • AZSMO-23

    CAS:
    <p>AZSMO-23 activates hERG K+ channels; blocks hKv4.3-hKChIP2.2, hCav3.2, hKv1.5; activates hCav1.2/β2/α2δ.</p>
    Formula:C19H13ClN4O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:348.79
  • Halofantrine

    CAS:
    <p>Halofantrine: antimalarial, lipophilic, blocks HERG K+ channels, targets Chloroquine-resistant P. falciparum.</p>
    Formula:C26H30Cl2F3NO
    Color and Shape:Solid
    Molecular weight:500.42
  • Diltiazem malate

    CAS:
    <p>Diltiazem malate is an ACE inhibitor and non-dihydropyridine calcium channel blocker used in the treatment of hypertension.</p>
    Formula:C26H32N2O9S
    Color and Shape:Solid
    Molecular weight:548.60
  • (R)-Amlodipine

    CAS:
    <p>(R)-Amlodipine is the R-enantiomer of Amlodipine and functions as an orally active dihydropyridine calcium channel blocker with antianginal properties.</p>
    Formula:C20H25ClN2O5
    Purity:99.977%
    Color and Shape:Solid
    Molecular weight:408.88
  • AMG9090

    CAS:
    <p>AMG9090 is a transient receptor potential ankyrin 1 (TRPA1) antagonist.</p>
    Formula:C15H11Cl4NOS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:395.13
  • U-7524

    CAS:
    <p>U-7524 (AOAA), an inhibitor of GABA-T and other PLP-dependent enzymes, disrupts the Schiff base linkage, forming oxime complexes.</p>
    Formula:C2H5NO3
    Color and Shape:Solid
    Molecular weight:91.07
  • 2-Hydroxysaclofen

    CAS:
    <p>2-Hydroxysaclofen is a GABAB receptor antagonist.</p>
    Formula:C9H12ClNO4S
    Purity:98%
    Color and Shape:White Solid
    Molecular weight:265.71
  • CXL-1020

    CAS:
    <p>CXL-1020, a HNO prodrug, enhances heart muscle function &amp; relaxation, aiding in heart failure research.</p>
    Formula:C7H9NO5S2
    Color and Shape:Solid
    Molecular weight:251.28
  • 3-Methyl-GABA

    CAS:
    <p>3-Methyl-GABA activates GABA aminotransferase, fits GABAaR, stimulates GAD, and acts as an anticonvulsant.</p>
    Formula:C20H30N2O10S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:522.59
  • Ethyl dirazepate

    CAS:
    <p>Ethyl dirazepate has anxiolytic and hypnotic and possibly other characteristic benzodiazepine properties,is a drug which is a benzodiazepine derivative.</p>
    Formula:C18H14Cl2N2O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:377.22
  • UBP301

    CAS:
    <p>UBP301 is a kainate receptor antagonist.</p>
    Formula:C15H14IN3O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:459.19
  • CGS 20625

    CAS:
    <p>partial agonist for the benzodiazepine binding site of the GABAA receptor</p>
    Formula:C18H19N3O2
    Purity:99.61%
    Color and Shape:Solid
    Molecular weight:309.36
  • Felbamate hydrate

    CAS:
    <p>Felbamate hydrate is an effective nonsedative anticonvulsant. It is a clinical effect that may be related to the inhibition of N-methyl-D-aspartate.</p>
    Formula:C11H16N2O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:256.26
  • Arbaclofen placarbil

    CAS:
    <p>Arbaclofen placarbil is a GABA(B) receptor agonist with better ADMET than R-baclofen, reducing postprandial reflux in GERD.</p>
    Formula:C19H26ClNO6
    Color and Shape:Solid
    Molecular weight:399.87
  • Cavα2δ1&NET-IN-1

    CAS:
    <p>Cavα2δ1&amp;NET-IN-1 .</p>
    Formula:C23H26N4O2S
    Color and Shape:Solid
    Molecular weight:422.54
  • Posenacaftor

    CAS:
    <p>Posenacaftor (PTI-801) regulates CFTR protein for cystic fibrosis research.</p>
    Formula:C27H27NO5
    Color and Shape:Solid
    Molecular weight:445.51
  • Carburazepam

    CAS:
    <p>Carburazepam is a derivate of benzodiazepines. Benzodiazepines are a class of psychoactive drugs.</p>
    Formula:C17H16ClN3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:329.78
  • Cibenzoline

    CAS:
    Cibenzoline: antiarrhythmic, blocks KATP channels, minimizes LVPG, useful in hypertrophic cardiomyopathy studies.
    Formula:C18H18N2
    Color and Shape:Solid
    Molecular weight:262.35
  • URAT1&XO inhibitor 2

    CAS:
    <p>Compound BDEO (URAT1&amp;XO inhibitor 2) serves as a dual-action inhibitor targeting both xanthine oxidase (XO) and URAT1, demonstrating an IC50 value of 3.3 μM for</p>
    Formula:C14H12BrNO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:322.15
  • TCS 1105

    CAS:
    <p>TCS 1105 is a GABAA BZR ligand, blocking Sema3A and altering mouse anxiety, aggression, and social dominance.</p>
    Formula:C17H13FN2O2
    Purity:99.75%
    Color and Shape:Solid
    Molecular weight:296.3
  • (R)-CPP

    CAS:
    <p>(R)-CPP is a NMDA antagonist.</p>
    Formula:C8H17N2O5P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:252.2
  • PD-151307

    CAS:
    PD-151307 is used as an N-type calcium channel blocker.
    Formula:C33H47N3O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:565.74
  • SN05

    CAS:
    <p>SN05 inhibits AAT with Ki: ASCT1 (2.77μM), rASCT2 (0.73μM), hASCT2 (0.87μM), EAAT1-5 (3.7-7.25μM); used in cancer research.</p>
    Formula:C18H17NO4
    Color and Shape:Solid
    Molecular weight:311.33
  • Sematilide

    CAS:
    <p>Sematilide is a blocker of selective IKr channel.</p>
    Formula:C14H23N3O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:313.42
  • TRAM 39

    CAS:
    <p>TRAM 39 (2-Chloro-α,α-diphenylbenzeneacetonitrile) is a selective blocker of intermediate-conductance Ca2+-activated K+channels.</p>
    Formula:C20H14ClN
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:303.78
  • MK-0343

    CAS:
    <p>MK0343 is an orally bioavailable GABAA receptor subtype-selective partial agonist and is a non-sedating anxiolytic.</p>
    Formula:C19H17F2N7O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:397.38
  • RU 33965

    CAS:
    <p>RU 33965, a 3-cyclopropyl carbonyl imidazobenzodiazepine, act as a low-efficacy benzodiazepine receptor inverse agonist.</p>
    Formula:C16H15N3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:281.31
  • Dihydrocapsiate

    CAS:
    <p>Dihydrocapsiate is a compound of capsinoid family that can be used in metabolism diseas research. Dihydrocapsiate is an orally active agonist of TRPV1 [1].</p>
    Formula:C18H28O4
    Color and Shape:Solid
    Molecular weight:308.41
  • BTG-1640

    CAS:
    <p>BTG-1640 is used potentially for the treatment of anxiety and panic disorder.</p>
    Formula:C15H19NO2
    Color and Shape:Solid
    Molecular weight:245.32
  • MCC-134

    CAS:
    <p>MCC-134 is an inverse agonist for the pancreatic-type ATP-sensitive K(+) channel. It also used as a vascular relaxing agent.</p>
    Formula:C16H17N3OS
    Color and Shape:Solid
    Molecular weight:299.39
  • (Rac)-MEM 1003

    CAS:
    <p>MEM-1003, a calcium channel blocker, is used potentially for the treatment of bipolar disorders.</p>
    Formula:C22H25ClN2O5
    Color and Shape:Solid
    Molecular weight:432.9
  • (S)-AMPA

    CAS:
    <p>(S)-AMPA is an active isomer of AMPA and a selective agonist of AMPA.</p>
    Formula:C7H10N2O4
    Color and Shape:Solid
    Molecular weight:186.17
  • Tracazolate hydrochloride

    CAS:
    <p>Tracazolate hydrochloride (Tracazolate (hydrochloride)) is a modulator of the GABAA receptor with anxiolytic and anticonvulsant activity.</p>
    Formula:C16H25ClN4O2
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:340.85
  • 17-PA

    CAS:
    <p>17-PA is a GABAA receptor antagonist.</p>
    Formula:C25H34O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:350.54
  • DDO-02005 free base

    CAS:
    <p>DDO-02005 is a potent Kv1.5 inhibitor with IC50 of 0.72μM, showing strong anti-arrhythmic and anti-AF effects in rat models.</p>
    Formula:C21H25N3O2
    Color and Shape:Solid
    Molecular weight:351.44
  • NS-8

    CAS:
    <p>NS-8, a pyrrole, activates Ca2+-sensitive K+ channels, reducing urinary frequency by inhibiting pelvic nerve activity.</p>
    Formula:C12H10FN3
    Color and Shape:Solid
    Molecular weight:215.23
  • mGAT3/4-IN-1

    CAS:
    <p>mGAT3/4-IN-1 inhibits mGAT3/4 with pIC50: 5.31/5.24, reduces neuropathic pain in diabetic mice.</p>
    Formula:C26H31ClN2O2S2
    Color and Shape:Solid
    Molecular weight:503.12
  • Sadopine

    CAS:
    <p>Sadopine is a high-affinity radioligand for DHP receptor in L-type Ca2+ channels, suitable for tissue and membrane labeling.</p>
    Formula:C30H40F3N3O7S
    Color and Shape:Solid
    Molecular weight:643.71
  • P2X7 receptor antagonist-2

    CAS:
    <p>P2X7 receptor antagonist-2: potent, pIC50 6.5-7.5, reduces neuroinflammation.</p>
    Formula:C19H18Cl2N2O2
    Color and Shape:Solid
    Molecular weight:377.26
  • Ro 04-5595 hydrochloride

    CAS:
    <p>NR2B-containing NMDA receptors antagonist</p>
    Formula:C19H23Cl2NO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:368.3
  • Bts 39542

    CAS:
    <p>Bts 39542 is a diuretic that plays a major role in the Henle circulation and increases renal blood flow without affecting glomerular filtration rate.</p>
    Formula:C16H11ClN4O3S
    Color and Shape:Solid
    Molecular weight:374.8
  • UBP646

    CAS:
    <p>UBP646 is a GluN1/GluN2 receptors potentiator.</p>
    Formula:C21H22O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:306.4
  • Zonampanel

    CAS:
    <p>Zonampanel is a selective glutamate receptor subtype, α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor antagonist.</p>
    Formula:C13H9N5O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:331.24
  • GAL-021 sulfate

    CAS:
    <p>GAL-021 sulfate is a BKCa channel blocker that inhibits the analgesic effects of opioids and is used in the study of respiratory control diseases.</p>
    Formula:C11H24N6O5S
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:352.41
  • NMDA receptor modulator 2

    CAS:
    <p>NMDA receptor modulator 2 (Compound 1) is a potent modulator of the NMDA receptor that can be used for neurological disorder research [1].</p>
    Formula:C13H11F3N2O2
    Color and Shape:Solid
    Molecular weight:284.23
  • NAP-1

    CAS:
    <p>NAP-1 is an anesthetic that enhances CA1 brain inhibition in rats and causes tadpole sedation (EC50 = 0.53 μM).</p>
    Formula:C20H18ClNO2
    Color and Shape:Solid
    Molecular weight:339.82
  • JNJ-39729209

    CAS:
    <p>JNJ-39729209 is a TRPV1 antagonist.</p>
    Formula:C19H11Cl2F3N4S
    Color and Shape:Solid
    Molecular weight:455.28
  • Omeprazole magnesium

    CAS:
    <p>Omeprazole magnesium: oral PPI that reduces stomach acid, treats acid reflux and heartburn.</p>
    Formula:C34H36MgN6O6S2
    Color and Shape:Solid
    Molecular weight:713.12
  • TRPC5-IN-2

    CAS:
    <p>TRPC5-IN-2 is a potent inhibitor of TRPC5.</p>
    Formula:C17H14ClF3N6O
    Color and Shape:Solid
    Molecular weight:410.78
  • CGP 39551

    CAS:
    <p>CGP 39551 is a NMDA antagonist.</p>
    Formula:C8H16NO5P
    Purity:98%
    Color and Shape:White Solid
    Molecular weight:237.19
  • Norverapamil

    CAS:
    <p>Norverapamil is a blocker of L-type calcium channel and an inhibitor of P-glycoprotein (P-gp) function .</p>
    Formula:C26H36N2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:440.58
  • bis(7)-Tacrine

    CAS:
    <p>Bis(7)-tacrine dihydrochloride: dimeric AChE inhibitor; may treat Alzheimer's; blocks NMDA, antagonizes GABA A.</p>
    Formula:C33H42Cl2N4
    Color and Shape:Solid
    Molecular weight:565.63
  • UBP-282

    CAS:
    <p>AMPA and kainate receptor antagonist</p>
    Formula:C15H15N3O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:333.3
  • AS1928370

    CAS:
    <p>AS1928370 is an antagonist of transient receptor potential vanilloid 1 (TRPV1).</p>
    Formula:C29H31N3O2
    Color and Shape:Solid
    Molecular weight:453.58
  • Galicaftor

    CAS:
    <p>ABBV-2222 is a CFTR corrector which is studied for the treatment of cystic fibrosis (CF).</p>
    Formula:C28H21F4NO7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:559.46
  • SKF 97541

    CAS:
    <p>GABAB agonist</p>
    Formula:C4H12NO2P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:137.12
  • BHF-177

    CAS:
    <p>BHF-177 is a positive allosteric modulator of the GABAB receptor. BHF-177 reduces self-administration of nicotine in animal studies.</p>
    Formula:C19H20F3N3
    Color and Shape:Solid
    Molecular weight:347.38
  • FCPT

    CAS:
    <p>FCPT is an ATP competitive kinesin-5 inhibitor.</p>
    Formula:C17H13FN2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:296.36
  • NAB-14

    CAS:
    <p>NAB-14: non-competitive GluN2C/D antagonist, IC50 580 nM for GluN1/2D, &gt;800x selectivity over GluN2A/B, blood-brain-barrier penetrant.</p>
    Formula:C20H21N3O3
    Color and Shape:Solid
    Molecular weight:351.4
  • Ac32Az19

    CAS:
    <p>Ac32Az19 is a potent, non-toxic, and highly selective inhibitor of Breast Cancer Resistance Protein (BCRP), demonstrating an EC50 of 13 nM in BCRP-overexpressed</p>
    Formula:C37H33N3O6
    Color and Shape:Solid
    Molecular weight:615.67
  • GABAA receptor agent 7

    CAS:
    <p>Compound 5c, a GABAA receptor modulator with anticonvulsant properties and low neurotoxicity, is promising for epilepsy research.</p>
    Formula:C18H13ClN4O
    Color and Shape:Solid
    Molecular weight:336.77
  • ZK93423

    CAS:
    <p>ZK93423: potent benzodiazepine agonist, IC50=1nM, non-selective, Ki=4.1-6nM for α1-α5 GABAA subunits.</p>
    Formula:C23H22N2O4
    Color and Shape:Solid
    Molecular weight:390.43
  • Y-26763

    CAS:
    Y-26763 is a K+ channel opener and active metabolite of Y-27152. This is an ATP-sensitive K+ (KATP) channel activator.
    Formula:C14H16N2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:276.29
  • AMG-1

    CAS:
    <p>AMG-1 inhibits CRAC channels, blocks effector T cells, not regulatory ones, and reduces EAE progression.</p>
    Formula:C18H9ClF5N3O
    Color and Shape:Solid
    Molecular weight:413.73
  • Istaroxime hydrochloride

    CAS:
    <p>Istaroxime hydrochloride (PST2744 hydrochloride) is a Na+/K+-ATPase inhibitor and SERCA 2 activator, and is a novel positive inotropic compound.</p>
    Formula:C21H33ClN2O3
    Color and Shape:Solid
    Molecular weight:396.95
  • Ethacrynate Sodium

    CAS:
    <p>Ethacrynate Sodium, a sodium salt, blocks chloride, potassium, and sodium transport mainly in Henle's loop.</p>
    Formula:C13H12Cl2NaO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:326.12
  • Efflux inhibitor-1

    CAS:
    <p>Efflux inhibitor-1 is a pyrazolopyrimidine efflux inhibitor.</p>
    Formula:C28H25N5O3
    Color and Shape:Solid
    Molecular weight:479.53
  • (Rac)-NMDAR antagonist 1

    CAS:
    <p>(Rac)-NMDAR antagonist 1 is a racemate of NMDAR antagonist 1. NMDAR antagonist 1 is a potent, orally active, NR2B-selective NMDAR antagonist.</p>
    Formula:C20H20BrN3O2
    Color and Shape:Solid
    Molecular weight:414.3
  • P-gp inhibitor 3


    <p>P-gp inhibitor 3 boosts Paclitaxel's effect by strongly reversing MDR via P-gp efflux blockade.</p>
    Formula:C48H67N3O6
    Color and Shape:Solid
    Molecular weight:782.06
  • Clobutinol

    CAS:
    <p>Clobutinol has anti-tussive effects. Clobutinol affects heart rate and blood pressure, it can be used for cough related research [1] [2] [3].</p>
    Formula:C14H22ClNO
    Color and Shape:Solid
    Molecular weight:255.78
  • (R)-Posenacaftor sodium

    CAS:
    <p>(R)-Posenacaftor sodium is a modulator for correcting cystic fibrosis protein folding.</p>
    Formula:C27H27NNaO5
    Color and Shape:Solid
    Molecular weight:468.505
  • P-CAB agent 2 hydrochloride

    CAS:
    <p>P-CAB agent 2 hydrochloride is a strong oral gastric acid secretion inhibitor with IC50 &lt;100 nM on H+/K+ ATPase and 18.69 µM on hERG channel, non-toxic.</p>
    Formula:C22H26ClFN2O4S
    Color and Shape:Solid
    Molecular weight:468.97
  • SK3 Channel-IN-1

    CAS:
    <p>SK3 Channel-IN-1: Potent, selective SK3 modulator; inhibits MDA-MB-435 migration, low cytotoxicity.</p>
    Formula:C25H49NO
    Color and Shape:Solid
    Molecular weight:379.66
  • Xininurad

    CAS:
    <p>Xininurad (XNW3009) is a urate transporter (URAT) inhibitor.</p>
    Formula:C15H10Br2FN3O2
    Color and Shape:Solid
    Molecular weight:443.07
  • MRS-1477

    CAS:
    <p>MRS-1477 is used as a TRPV1 positive allosteric modulator (PAM).</p>
    Formula:C21H27NO4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:389.51
  • Cgp 31358

    CAS:
    <p>CGP 31358 is a new chemical that targets the NMDA receptor, potentially aiding in molecular pharmacology research.</p>
    Formula:C19H19ClN4O2
    Color and Shape:Solid
    Molecular weight:370.83
  • (1R,2R)-ML-SI3

    CAS:
    <p>(1R,2R)-ML-SI3 ((-)-trans-ML-SI3) is a selective TRPML1, TRPML2, and TRPML3 inhibitor for the study of neurodegenerative and cardiovascular diseases.</p>
    Formula:C23H31N3O3S
    Color and Shape:Solid
    Molecular weight:429.58
  • GLPG-3221

    CAS:
    <p>GLPG-3221, a potent oral CFTR corrector for cystic fibrosis treatment, has an EC50 of 105 nM.</p>
    Formula:C30H37F3N2O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:578.62
  • IDO1-IN-19

    CAS:
    <p>IDO1-IN-19 (Compound 17) is a potent inhibitor of IDO1 and has potential for cancer disease research.</p>
    Formula:C25H22F4N2O3
    Color and Shape:Solid
    Molecular weight:474.45
  • AMG-628

    CAS:
    <p>AMG-628 inhibits RAF kinase, halts growth, and triggers apoptosis in B-RAFV600E mutant colon/melanoma cells.</p>
    Formula:C25H25FN6O2S
    Color and Shape:Solid
    Molecular weight:492.57
  • P2X7 receptor antagonist-3

    CAS:
    <p>P2X7 receptor antagonist-3 is a powerful inhibitor of the P2X7 receptor, exhibiting IC50 values of 4.2 nM in humans and 6.8 nM in rats, indicating its high</p>
    Formula:C17H12ClF3N6O
    Color and Shape:Solid
    Molecular weight:408.77
  • FFN200 dihydrochloride

    CAS:
    <p>FFN200 is a vesicular monoamine transporter 2 (VMAT2) substrate that selectively traces monoamine exocytosis in both neuronal cell culture and brain tissue.</p>
    Formula:C11H14Cl2N2O2
    Color and Shape:Solid
    Molecular weight:277.15
  • GV-196771A

    CAS:
    <p>GV-196771A A novel NMDA receptor glycine site antagonist with potent antinociceptive activity.</p>
    Formula:C20H13Cl2N2NaO3
    Purity:96.43%
    Color and Shape:Solid
    Molecular weight:423.23
  • Ivabradine

    CAS:
    <p>Ivabradine: oral HCN blocker, lowers heart rate without affecting blood pressure, has anticonvulsant and anti-anginal properties.</p>
    Formula:C27H36N2O5
    Color and Shape:Solid
    Molecular weight:468.59
  • SN40

    CAS:
    <p>SN40: AAT inhibitor for cancer research; inhibits hASCT1 (7.29 μM), rASCT2 (2.42 μM), hASCT2 (2.94 μM), EAAT1/EAAC1/EAAT5 (5.55 μM), EAAT2 (24.43 μM).</p>
    Formula:C18H20N2O2
    Color and Shape:Solid
    Molecular weight:296.36
  • Cl-HIBO

    CAS:
    <p>desensitising AMPA receptor agonist</p>
    Formula:C6H7ClN2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:206.58
  • TRPC6-IN-1

    CAS:
    <p>TRPC6-IN-1 is an inhibitor of the Transient Receptor Potential Canonical 6 Channel (TRPC6) (EC50: 4.66 μM).</p>
    Formula:C21H23FN4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:398.43
  • NHE3-IN-2

    CAS:
    <p>NHE3-IN-2 is an inhibitor of NHE3 (Na+/H+ exchanger-3), applicable for treating hypertension, thrombosis, and ischaemic diseases.</p>
    Formula:C15H12ClN5
    Color and Shape:Solid
    Molecular weight:297.74
  • Irampanel

    CAS:
    <p>Irampanel is a neuroprotectant and anticonvulsant.</p>
    Formula:C18H19N3O2
    Color and Shape:Solid
    Molecular weight:309.36
  • F15845

    CAS:
    <p>F 15845: potent sodium current blocker, anti-ischemic, offers short/long-term post-infarction cardioprotection.</p>
    Formula:C20H25NO2S2
    Color and Shape:Solid
    Molecular weight:375.55
  • GYKI 52466 HCl

    CAS:
    <p>GYKI 52466 is an AMPA antagonist with IC50 of 7.5 µM, also blocking kainate currents (IC50 11 µM) and reduces EPSCs and seizures in rats.</p>
    Formula:C17H16ClN3O2
    Color and Shape:Solid
    Molecular weight:329.784
  • Nemadipine-A

    CAS:
    <p>Nemadipine A blocks L-type Ca2+ channels, alters C. elegans morphology, boosts TRAIL's cancer kill rate, and lowers Survivin in A549 cells.</p>
    Formula:C19H18F5NO4
    Color and Shape:Solid
    Molecular weight:419.34
  • KR 60436

    CAS:
    <p>KR 60436 is an inhibitor of potassium hydrogen ATPase.</p>
    Formula:C22H22F3N3O3
    Color and Shape:Solid
    Molecular weight:433.42
  • Zoniporide dihydrochloride

    CAS:
    <p>Sodium-hydrogen exchanger isoform 1 (NHE1) inhibitor</p>
    Formula:C17H18Cl2N6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:393.27
  • 5,7-Dichlorokynurenic acid sodium salt

    CAS:
    <p>5,7-Dichlorokynurenic acid sodium salt is a NMDA receptor antagonist.</p>
    Formula:C10H5Cl2NNaO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:281.05
  • (R)-Olacaftor

    CAS:
    <p>(R)-Olacaftor (VX-440) is a CFTR modulator with promise for researching cystic fibrosis.</p>
    Formula:C29H34FN3O4S
    Color and Shape:Solid
    Molecular weight:539.66
  • Traxoprodil Mesylate

    CAS:
    <p>Traxoprodil Mesylate is a potent noncompetitive N-methyl-D-aspartate (NMDA) receptors antagonist and has selective for the NR2B subunit.</p>
    Formula:C21H29NO6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:423.52
  • NS 3763

    CAS:
    <p>NS 3763 is a kainate receptor antagonist.</p>
    Formula:C22H16N2O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:404.37
  • A1899

    CAS:
    <p>A1899 is a effective and selective TASK-1 and TASK-3 antagonist.</p>
    Formula:C30H26F2N2O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:500.54
  • JNJ-54166060

    CAS:
    <p>JNJ-54166060 is a potent and selective antagonist of P2X7 receptor, with IC 50 s of 4/115/72 nM for human/rat/mouse P2X7 receptor, respectively [1].</p>
    Formula:C20H15ClF4N4O
    Color and Shape:Solid
    Molecular weight:438.81
  • L-AP5

    CAS:
    <p>L-AP5 is a NMDA antagonist.</p>
    Formula:C5H12NO5P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:197.13
  • UMB68 sodium

    CAS:
    <p>UMB-68 is a GHB receptor ligand with no affinity (IC(50) &gt;100 microM) at GABA(A) or GABA(B) receptors.</p>
    Formula:C6H12NaO3
    Color and Shape:Solid
    Molecular weight:155.149
  • Cgp 55802A

    CAS:
    <p>CGP 55802A is a novel photoaffinity ligand for in-situ labeling of NMDA receptors.</p>
    Formula:C18H24IN5NaO7P
    Color and Shape:Solid
    Molecular weight:603.286
  • PPPA

    CAS:
    <p>PPPA is a NMDA receptor antagonist.</p>
    Formula:C9H18NO5P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:251.22
  • PA1 2HCl

    CAS:
    <p>PA1 2HCl is a blocker of photoswitchable epithelial sodium channel (ENaC).</p>
    Formula:C18H16ClN9O
    Color and Shape:Solid
    Molecular weight:409.83
  • Lercanidipine. (R)-

    CAS:
    <p>(R)-Lercanidipine enantiomer: antihypertensive, blocks L-type Ca2+ channels, dilates blood vessels.</p>
    Formula:C36H41N3O6
    Color and Shape:Solid
    Molecular weight:611.73
  • Remacemide hydrochloride

    CAS:
    <p>Remacemide hydrochloride is a NMDA receptor antagonist.</p>
    Formula:C17H21ClN2O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:304.81
  • LY382884

    CAS:
    <p>LY382884 is a selective and potent GluR5 kainate receptor antagonist with anxiolytic activity.LY382884 blocks blockade of mossy fibre LTP induction.</p>
    Formula:C18H23NO4
    Purity:98.32% - 98.71%
    Color and Shape:Solid
    Molecular weight:317.38
  • OptoBI-1

    CAS:
    <p>OptoBI-1 是一种光敏分子,是光致变色的TRPC3激动剂,可用作控制神经元放电的光药理学工具。</p>
    Formula:C32H37N5O2
    Color and Shape:Soild
    Molecular weight:523.67
  • CGS8216

    CAS:
    <p>CGS8216 shows analgesic activity at high doses, has anxiolytic activity, and can be used to study immune system disorders.</p>
    Formula:C16H11N3O
    Purity:98.53%
    Color and Shape:Solid
    Molecular weight:261.28
  • 4,9-Anhydrotetrodotoxin

    CAS:
    <p>4,9-anhydro-TTX blocks Nav1.6 channels (IC50=7.8 nM); has varying IC50 for Nav1.2-Nav1.8.</p>
    Formula:C11H15N3O7
    Color and Shape:Solid
    Molecular weight:301.25
  • RA-2

    CAS:
    <p>RA-2 is a pan-negative-gating modulator of KCa2/3 channels that acts by inhibiting EDH-type relaxation in coronary arteries.</p>
    Formula:C22H16F2O6
    Color and Shape:Solid
    Molecular weight:414.36
  • TC-N 1752

    CAS:
    <p>TC-N 1752 is an orally active inhibitor of Nav1.7 channel with IC50 of 0.17 μM. TC-N 1752 shows analgesic activities.</p>
    Formula:C25H27F3N6O3
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:516.52
  • R(+)-IAA-94

    CAS:
    <p>R(+)-IAA-94 (Methylindazone) blocks epithelial chloride channels; inhibits Nef-sdAb19 binding.</p>
    Formula:C17H18Cl2O4
    Purity:98.95% - 99.17%
    Color and Shape:Solid
    Molecular weight:357.23
  • Enecadin

    CAS:
    <p>Enecadin is a neuroprotective agent.</p>
    Formula:C21H28FN3O
    Purity:98.53%
    Color and Shape:Solid
    Molecular weight:357.46
  • Butibufen

    CAS:
    <p>Butibufen (FF-106) is a non-steroidal anti-inflammatory compound and LOX inhibitor with analgesic and antipyretic activity for the study of rheumatic diseases.</p>
    Formula:C14H20O2
    Purity:98.11% - 98.91%
    Color and Shape:Solid
    Molecular weight:220.31
  • Ani9

    CAS:
    <p>Ani9 selectively blocks ANO1/TMEM16A with a 77 nM IC50, useful for ANO1 research and treating cancer, hypertension, pain, diarrhea, asthma.</p>
    Formula:C17H17ClN2O3
    Purity:99.73%
    Color and Shape:Solid
    Molecular weight:332.78
  • SKA-111

    CAS:
    <p>SKA-111 activates KCa3.1 potassium channels, modulates membrane potential in endothelial cells, and dilates rat coronary arteries.</p>
    Formula:C12H10N2S
    Purity:99.9%
    Color and Shape:Solid
    Molecular weight:214.29
  • Gallopamil

    CAS:
    <p>Gallopamil blocks acid secretion (IC50: 10.9 μM), acts as antiarrhythmic, vasodilator, and is a methoxy Verapamil derivative.</p>
    Formula:C28H40N2O5
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:484.63
  • UCCF-853

    CAS:
    <p>UCCF-853 是一种小分子 CFTR 调节剂,可用于研究囊性纤维化。</p>
    Formula:C14H8ClF3N2O
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:312.67
  • DMCM hydrochloride

    CAS:
    <p>DMCM hydrochloride is a non-selective fully inverse agonist of benzodiazepine.</p>
    Formula:C17H19ClN2O4
    Purity:99.56%
    Color and Shape:Solid
    Molecular weight:350.8
  • TWIK-1/TREK-1-IN-3

    CAS:
    <p>TWIK-1/TREK-1-IN-3 is a potassium channel TREK-1 inhibitor TWIK-1/TREK-1-IN-3 has antidepressant activity and can be used to study depression.</p>
    Formula:C19H27F3N2O2
    Purity:99.04%
    Color and Shape:Solid
    Molecular weight:372.43
  • AV-101

    CAS:
    <p>AV-101 (4-Cl-KYN) is a prodrug antagonist at the glycine site of the NMDA receptor with antidepressant activity that reduces dyskinesia.</p>
    Formula:C10H11ClN2O3
    Purity:97.78% - 98.27%
    Color and Shape:Solid
    Molecular weight:242.66
  • Neboglamine hydrochloride

    CAS:
    <p>Neboglamine (CR-2249, XY-2401) hydrochloride boosts NMDA receptor, aids schizophrenia research, and is orally active.</p>
    Formula:C13H25ClN2O3
    Purity:99.19%
    Color and Shape:Solid
    Molecular weight:292.8
  • Transcainide

    CAS:
    <p>Transcainide (R 54718), an oral lidocaine-like antiarrhythmic, blocks BTX-activated Na+ channels in heart/muscle.</p>
    Formula:C22H35N3O2
    Purity:99.81%
    Color and Shape:Solid
    Molecular weight:373.53
  • FR-167356

    CAS:
    <p>FR-167356 inhibits a3 isoform H⁺-ATPase (IC50: 170-370 nM), targeting osteoclasts, kidneys, macrophages; reduces B16-F10 bone metastasis.</p>
    Formula:C19H17Cl2NO3
    Purity:98.44% - 99.74%
    Color and Shape:Solid
    Molecular weight:378.25
  • BPDBA

    CAS:
    <p>BPDBA is an effective, selective, and non-competitive inhibitor of the betaine/GABA transporter (BGT-1), displaying inhibitory activity against human BGT-1 and</p>
    Formula:C19H20Cl2N2O
    Purity:99.37% - 99.95%
    Color and Shape:Solid
    Molecular weight:363.28
  • XE991

    CAS:
    <p>XE991 is a Kv7 (KCNQ) channel blocker.XE 991 dihydrochloride inhibits Kv7.1 (KCNQ1) and M-current and can be used in the study of neurological disorders.</p>
    Formula:C26H20N2O
    Purity:98.87%
    Color and Shape:Solid
    Molecular weight:376.45
  • SCH28080

    CAS:
    <p>SCH28080 is a reversible and K+-competitive inhibitor of gastric H+/K+-ATPase with an IC50 value of 20 nM (rabbit microsomal membrane).SCH28080 is a potent</p>
    Formula:C17H15N3O
    Purity:99.24%
    Color and Shape:Solid
    Molecular weight:277.32
  • CP-060

    CAS:
    <p>CP-060 is a potent Ca2+ antagonist and inhibits Ca2+ overload with antioxidant and cardioprotective activities.</p>
    Formula:C30H42N2O5S
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:542.73