Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(93 products)
- Adiponectin receptor(5 products)
- CFTR(64 products)
- CGRP Receptor(52 products)
- Calcium Channel(496 products)
- Chloride channel(49 products)
- GABA Receptor(337 products)
- Monoamine Transporter(23 products)
- Monocarboxylate transporter(17 products)
- NKCC(2 products)
- NPC1L1(3 products)
- Na-K-Cl cotransporter(8 products)
- OAT(27 products)
- OCT(7 products)
- P-gp(53 products)
- Potassium Channel(277 products)
- Proton pump(39 products)
- SGLT(30 products)
- Sodium Channel(202 products)
- TRP/TRPV Channel(93 products)
Show 13 more subcategories
Found 2293 products of "Membrane Transporter/Ion Channel"
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AMPA receptor modulator-2
CAS:<p>AMPA receptor modulator-2 is a modulator of AMPA receptor. The pIC50 value for TARPγ2 dependent AMPA receptor is 10.1.</p>Formula:C15H6F6N4OSPurity:99.8%Color and Shape:SolidMolecular weight:404.29BTG 502
CAS:<p>BTG 502 is an alkylamide insecticide that binds to voltage-gated sodium channels, antagonising the activation of sodium channels by Batrachotoxin (BTX).</p>Formula:C21H24BrNOPurity:99.30%Color and Shape:SolidMolecular weight:386.33XR9051
CAS:<p>XR9051, a synthetic derivative of a natural compound, potently reverses P-glycoprotein MDR (EC50 = 1.4 nM) by inhibiting cytotoxic binding.</p>Formula:C39H38N4O5Color and Shape:SolidMolecular weight:642.74Ritivixibat
CAS:<p>Ritivixibat inhibits IBAT and modulates bile acids, used in research for cardiovascular, metabolic, GI, and liver diseases.</p>Formula:C26H36N2O5S2Color and Shape:SolidMolecular weight:520.7ADCI
CAS:<p>ADCI inhibits voltage-activated sodium and NMDA channels; boosts dopamine metabolism in prefrontal cortex and nucleus accumbens.</p>Formula:C16H14N2OPurity:98%Color and Shape:SolidMolecular weight:250.3(-)-Bicuculline methochloride
CAS:<p>(-)-Bicuculline methochloride is a potent antagonist of GABAA receptor.</p>Formula:C21H20ClNO6Purity:98%Color and Shape:SolidMolecular weight:417.84CGP 54626 hydrochloride
CAS:<p>CGP 54626 hydrochloride is a GABAB receptor antagonist.</p>Formula:C18H29Cl3NO3PPurity:98%Color and Shape:SolidMolecular weight:444.76BMT-108908
CAS:<p>BMT-108908 is a Negative Allosteric Modulator. It is selective for the NR2B Subtype of The NMDA Receptor Impair Cognition in Multiple Domains.</p>Formula:C22H25FN2O2Color and Shape:SolidMolecular weight:368.44Y-27152
CAS:<p>Y-27152 is a prodrug of the KATP (Kir6) channel opener Y-26763 and is a long-acting K+ channel opener.</p>Formula:C21H22N2O4Purity:98%Color and Shape:SolidMolecular weight:366.41URAT1 inhibitor 1
CAS:URAT1 inhibitor 1 (1g) is an inhibitor of uric acid transporter 1 (URAT1) (IC50: 32 nM), has the potential to treat hyperuricemia associated with gout.Formula:C19H15Br2N5O2S2Purity:98%Color and Shape:SolidMolecular weight:569.29MK-8153
CAS:<p>MK-8153: Selective, potent ROMK inhibitor, orally active, IC50: ROMK EP 5 μM, hERG EP 34 μM; potential diuretic.</p>Formula:C24H28N2O6Color and Shape:SolidMolecular weight:440.4911-deoxy-PGF2a
CAS:<p>11-deoxy-PGF2a is a thromboxane A2 receptor agonist that partially alleviates crowding in Lpar3(−/−) female embryos and induces smooth muscle contraction</p>Formula:C20H34O4Color and Shape:SolidMolecular weight:338.48Zelquistinel
CAS:<p>Zelquistinel, an NMDA receptor agonist, aids research on depression, anxiety, and psychiatric disorders.</p>Formula:C15H25N3O5Color and Shape:SolidMolecular weight:327.38APS3
CAS:<p>APS3 is an inhibitor of GABA and nACh receptors, exhibiting an LC50 value of 7.2423 μg/mL against Plutella xylostella [1].</p>Formula:C18H7Cl2F6N5O5S2Color and Shape:SolidMolecular weight:622.31JYL-1511
CAS:<p>JYL-1511 is the TRPV1 channel partial agonist.</p>Formula:C21H29N3O3S2Purity:98%Color and Shape:SolidMolecular weight:435.6GABAA receptor agent 2 TFA
CAS:<p>Potent GABAA antagonist; IC50: 24 nM (α1β2γ2), Ki: 28 nM (rat); inactive on human GABA transporters.</p>Formula:C22H22F3N3O3Color and Shape:SolidMolecular weight:433.42ARN 11391
CAS:<p>ARN 11391 enhances the function of the IP3-gated calcium channel ITPR1 (Inositol 1,4,5-trisphosphate (IP3) receptor type 1), boosting intracellular calcium ion</p>Formula:C22H29N3O3Color and Shape:SolidMolecular weight:383.49D-erythro-Sphingosine hydrochloride
CAS:<p>D-erythro-Sphingosine HCl activates TRPM3 and dephosphorylates retinoblastoma protein.</p>Formula:C18H38ClNO2Color and Shape:SolidMolecular weight:335.95γ-Kainylglutamic acid
CAS:<p>gamma-Kainylglutamic acid is a selective amino acid-induced neuroexcitation antagonist.</p>Formula:C15H22N2O7Purity:98%Color and Shape:SolidMolecular weight:342.34FGIN-1-27
CAS:<p>FGIN-1-27 is a high-affinity agonist of the translocator protein and a specific peripheral benzodiazepine receptor (PBR) ligand(Ki = 5.0 nM).</p>Formula:C28H37FN2OPurity:99.86%Color and Shape:SolidMolecular weight:436.6AR-C141990
CAS:<p>AR-C141990 is a lactate transporters inhibitor.</p>Formula:C26H28N4O4SColor and Shape:SolidMolecular weight:492.59BMS-986169
CAS:<p>BMS-986169 is a high-affinity and selective negative allosteric modulator of the NMDA receptor GluN2B subunit, depression.</p>Formula:C23H27FN2O2Purity:97.61%Color and Shape:SolidMolecular weight:382.47A 425619
CAS:<p>A 425619 (1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA) is a potent TRPV1 antagonist</p>Formula:C18H14F3N3OPurity:99.75%Color and Shape:SolidMolecular weight:345.32Mioflazine
CAS:<p>Mioflazine suppresses nucleoside uptake. Mioflazine is an orally active nucleoside transport inhibitor. It has the potential for sleep disorders treatment.</p>Formula:C29H30Cl2F2N4O2Purity:98%Color and Shape:SolidMolecular weight:575.48U 89843A
CAS:<p>U 89843A is a positive allosteric modulator of gamma-aminobutyric acid (GABA)A receptors.</p>Formula:C16H23N5Purity:99.62%Color and Shape:SolidMolecular weight:285.39S-Pantoprazole sodium trihydrate
CAS:<p>S-Pantoprazole (sodium trihydrate), a variant of Pantoprazole, is pivotal in managing diseases associated with gastric acid secretion disorders, serving as a</p>Formula:C16H20F2N3NaO7SPurity:98%Color and Shape:SolidMolecular weight:459.4GMA-839
CAS:<p>GMA-839 is a selective modulator of gamma-aminobutyric acid(A) receptors.</p>Formula:C21H31F3O3Purity:98%Color and Shape:SolidMolecular weight:388.46AGN-201904Z
CAS:<p>AGN-201904Z is a slow-release, acid-resistant pro-PPI that turns into omeprazole, offering extended acid suppression.</p>Formula:C25H25N3NaO8S2Purity:98%Color and Shape:SolidMolecular weight:582.6AC-4
CAS:<p>AC-4 is a blocker of photoswitchable TRPV1 channel.</p>Formula:C26H25F3N4O2SColor and Shape:SolidMolecular weight:514.56Nepaprazole
CAS:<p>Nepaprazole (TY-11345) is a potent proton pump inhibitor; IC50: 5.8µM at pH 6.0, 9.9µM at pH 7.4. Better inhibition in weak acid.</p>Formula:C18H19N3O2SPurity:98%Color and Shape:SolidMolecular weight:341.43P-1075
CAS:<p>P-1075 activates SUR2-KIR6 channels at 45 nM; may open mitoKATP channels and protect the heart.</p>Formula:C12H17N5Purity:99.85%Color and Shape:SolidMolecular weight:231.33′-Acetate-ATP
CAS:<p>3’-Acetate-ATP, an analogue of ATP and its acetylation product, exhibits maximum ultraviolet absorption at 259 nm in neutral aqueous solutions.</p>Formula:C12H18N5O14P3Color and Shape:SolidMolecular weight:549.22NCS-382 sodium
CAS:<p>NCS-382 (sodium) is a potent antagonist of the GABA receptor, exhibiting anti-sedative and anti-hypnotic properties, with applications in neurological disease</p>Formula:C13H13NaO3Purity:98%Color and Shape:SolidMolecular weight:240.23NPEC-caged-(S)-AMPA
CAS:<p>AMPA receptor agonist</p>Formula:C16H17N3O8Purity:98%Color and Shape:SolidMolecular weight:379.32TRPC3/6-IN-2
CAS:<p>TRPC3/6-IN-2 is a potent inhibitor of TRPC3 and TRPC6, exhibiting IC50 values of 16 nM for TRPC3 and 29.8 nM for TRPC6, respectively [1].</p>Formula:C18H23F2N5Color and Shape:SolidMolecular weight:347.41L 663581
CAS:<p>L 663581 is the benzodiazepine receptor partial agonist.</p>Formula:C17H16ClN5O2Purity:98%Color and Shape:SolidMolecular weight:357.79TPA 023
CAS:<p>TPA 023 is a selective agonist of GABAA α2/α3 subtype (Kis = 0.19 - 0.41 nM).</p>Formula:C20H22FN7OPurity:99.75%Color and Shape:SolidMolecular weight:395.43Kv3 modulator 2
CAS:<p>Kv3 modulator 2 is a potent Kv3 channels modulator.has analgesic activity and is used in the prophylaxis or treatment of related disorders.</p>Formula:C21H21N3O4Purity:98%Color and Shape:SolidMolecular weight:379.41SLC13A5-IN-1
CAS:<p>SLC13A5-IN-1 is a selective inhibitor of sodium-citrate co-transporter (SLC13A5),completely blocks the uptake of 14C-citrate(IC50 : 0.022 μM in HepG2 cells).</p>Formula:C19H19Cl3N2O3SPurity:99.67%Color and Shape:SolidMolecular weight:461.79TRPC5-IN-3
CAS:<p>TRPC5-IN-3 is a potent TRPC5 inhibitor (IC50= 10.75 nM).</p>Formula:C18H15ClF3N5OColor and Shape:SolidMolecular weight:409.79VU0463271
CAS:<p>VU0463271: KCC2 antagonist, IC50 61 nM, >100x selective over NKCC1, inactive on other GPCRs, channels, transporters.</p>Formula:C19H18N4OS2Purity:97.84% - 99.55%Color and Shape:SolidMolecular weight:382.5Pristinamycin IA
CAS:<p>Pristinamycin IA (Mikamycin B) is a substrate for the P-glycoprotein and a cyclo-peptidic macrolactone antibiotic.</p>Formula:C45H54N8O10Purity:97.44%Color and Shape:SolidMolecular weight:866.96DNDS
CAS:<p>DNDS is a channel blocker of voltage-dependent cystic fibrosis transmembrane conductance regulator (CFTR).</p>Formula:C14H8N2Na2O10S2Purity:99.92%Color and Shape:Physical Description White Powder (Ntp 1992)Molecular weight:474.33NS1219
CAS:<p>NS1219, an isomer of NS1209, is a selective AMPA antagonist for studying stroke, neuropathic pain, and epilepsy.</p>Formula:C24H28N4O7SColor and Shape:SolidMolecular weight:516.57Sodium Channel inhibitor 4
CAS:<p>Sodium Channel Inhibitor 4 is a compound that functions as a sodium channel inhibitor [1].</p>Formula:C19H18ClN3O4S2Purity:98%Color and Shape:SolidMolecular weight:451.95PF 04531083
CAS:<p>PF 04531083 is a selective blocker of the NaV1.8 channel. PF 04531083 can be used for neuropathic and inflammatory pain studies.</p>Formula:C17H16ClN5O2Purity:99.85%Color and Shape:SolidMolecular weight:357.79(+)-Bicuculline methiodide
CAS:<p>(+)-Bicuculline methiodide is a GABAA receptor blocker that blocks epileptogens and may be used in the study of neurological disorders.</p>Formula:C21H20INO6Purity:99.24%Color and Shape:SolidMolecular weight:509.29Budiodarone
CAS:<p>Budiodarone (ATI-2042) resembles amiodarone, potentially preventing atrial fibrillation.</p>Formula:C27H31I2NO5Color and Shape:SolidMolecular weight:703.35Piperidine-4-sulfonic acid
CAS:<p>Piperidine-4-sulfonic acid is a potent GABA agonist, demonstrating an IC50 value of 0.034 μM for the inhibition of H-GABA binding [1].</p>Formula:C5H11NO3SPurity:98%Color and Shape:SolidMolecular weight:165.216,2'-Dihydroxyflavone
CAS:<p>6,2'-Dihydroxyflavone is a novel antagonist of GABAA receptor.</p>Formula:C15H10O4Purity:99.44% - 99.67%Color and Shape:SolidMolecular weight:254.24
