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Membrane Transporter/Ion Channel

Membrane Transporter/Ion Channel

Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.

Subcategories of "Membrane Transporter/Ion Channel"

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Found 2280 products of "Membrane Transporter/Ion Channel"

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  • S9-A13
    Targetmol
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    S9-A13

    CAS:
    <p>S9-A13 is a potent and selective inhibitor of SLC26A9, exhibiting an IC50 of 90.9 nM without inhibiting other members of the SLC26 family, such as SLC26A3, SLC26A4, and SLC26A6. It also inhibits the SLC26A9 Cl- current in cells lacking CFTR expression.</p>
    Formula:C20H18ClN3O2S
    Color and Shape:Solid
    Molecular weight:399.89

    Ref: TM-T201301

  • BGT1-IN-1
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    BGT1-IN-1

    CAS:
    <p>BGT1-IN-1 (compound 9) is an effective inhibitor of BGT1, demonstrating IC50 values of 13.9 µM for hBGT1 and 58.3 µM for GAT3. It exhibits no cytotoxic effects and possesses neuroprotective activity.</p>
    Formula:C6H9NO2
    Color and Shape:Solid
    Molecular weight:127.14

    Ref: TM-T200935

  • Caramboxin
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    Caramboxin

    CAS:
    <p>Caramboxin, a neurotoxin, can induce acute kidney injury.</p>
    Formula:C11H13NO6
    Color and Shape:Solid
    Molecular weight:255.22

    Ref: TM-T201088

  • RO-275
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    RO-275

    CAS:
    <p>RO-275 is an HCN1 inhibitor that also inhibits HCN2, HCN3, and HCN4, improving working memory deficits and being used in research on cognitive disorders.</p>
    Formula:C18H14ClN5O
    Purity:98.12% - 98.3%
    Color and Shape:Solid
    Molecular weight:351.79

    Ref: TM-T87339

  • CFTR corrector 17
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    CFTR corrector 17

    CAS:
    <p>CFTRcorrector 17 (example 17) is a regulator of the cystic fibrosis transmembrane conductance regulator (CFTR). It is utilized in the study of diseases mediated by CFTR.</p>
    Formula:C18H15FN2O2
    Color and Shape:Solid
    Molecular weight:310.32

    Ref: TM-T201013

  • LY503430
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    LY503430

    CAS:
    <p>LY503430: Oral AMPA enhancer with nootropic, neuroprotective properties, mitigates 6-OHDA/MPTP brain damage.</p>
    Formula:C20H25FN2O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:392.49

    Ref: TM-T27959

  • 4α-PDD
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    4α-PDD

    CAS:
    <p>4alpha-PDD activates transient receptor potential vanilloid 4 (TRPV4) channels and is inactive for signaling through PKC.</p>
    Formula:C40H64O8
    Color and Shape:Solid
    Molecular weight:672.93

    Ref: TM-T26386

  • Kv7.2/Kv7.3 activator-1
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    Kv7.2/Kv7.3 activator-1

    CAS:
    <p>Kv7.2/Kv7.3 Activator-1 (compound 517) serves as a powerful activator of the Kv7.2/Kv7.3 channels, exhibiting an EC50 value of less than 1 µM. It holds potential for use in neurological disease research.</p>
    Formula:C19H22F2N4O
    Color and Shape:Solid
    Molecular weight:360.40

    Ref: TM-T89880

  • SGE-516
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    SGE-516

    CAS:
    <p>SGE516: neuroactive steroid, enhances GABAA, lowers neuronal activity, protects from seizures.</p>
    Formula:C23H35N3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:385.54

    Ref: TM-T28766

  • CymitQuimica logo
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    MRS4738

    <p>MRS4738 is a potent antagonist with high affinity for the P2Y14R receptor. It demonstrates in vivo anti-hyperallodynic and antiasthmatic activity [1].</p>
    Formula:C30H24F3NO2
    Color and Shape:Solid
    Molecular weight:487.51

    Ref: TM-T63242

  • CymitQuimica logo
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    VU0463271 quarterhydrate

    <p>VU0463271 quarterhydrate is a potent KCC2 antagonist, with an IC 50 of 61 nM [1].</p>
    Formula:C19H20N4O2S2
    Color and Shape:Solid
    Molecular weight:387

    Ref: TM-T61725

  • (RS)-AMPA monohydrate
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    (RS)-AMPA monohydrate

    CAS:
    <p>(RS)-AMPA monohydrate, potent glutamate analogue, selectively activates L-glutamic acid without affecting kainic acid or NMDA receptors.</p>
    Formula:C7H12N2O5
    Color and Shape:Solid
    Molecular weight:204.182

    Ref: TM-T60242

  • Moxetomidate
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    Moxetomidate

    CAS:
    <p>Moxetomidate is a GABAA receptor (GABAA receptor) agonist with hypnotic properties.</p>
    Formula:C15H18N2O3
    Color and Shape:Solid
    Molecular weight:274.315

    Ref: TM-T205308

  • hURAT1 inhibitor 2
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    hURAT1 inhibitor 2

    CAS:
    <p>hURAT1 inhibitor 2 (Compound 5) is an inhibitor of hURAT1 (uric acid transporter 1, SLC22A12) with an IC50 of 18 nM. It also exhibits some inhibitory activity against OATP1B1, with an IC50 of 0.73 μM. hURAT1 inhibitor 2 can be used in research related to hyperuricemia, gout, and other diseases associated with abnormal uric acid metabolism.</p>
    Formula:C17H11Br2FO3
    Color and Shape:Solid
    Molecular weight:442.074

    Ref: TM-T206558

  • Lubeluzole dihydrochloride
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    Lubeluzole dihydrochloride

    CAS:
    <p>Lubeluzole (dihydrochloride) acts as a neuroprotective agent by blocking neuronal voltage-gated sodium channels and also affects cardiac sodium channels, exhibiting both tonic and blocking effects. This compound is considered promising in the research of antiarrhythmic agents.</p>
    Formula:C22H27Cl2F2N3O2S
    Color and Shape:Solid
    Molecular weight:506.44

    Ref: TM-T200178

  • PDE2 inhibitor 6
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    PDE2 inhibitor 6

    CAS:
    <p>PDE2 inhibitor6 (Compound 1) is an orally active phosphodiesterase (PDE) inhibitor, effectively inhibiting PDE2A, PDE3B, and PDE10A2 with IC50 values of 0.95 nM, 6.17 μM (pIC50=5.21), and 87.1 nM (pIC50=7.06), respectively. It modulates AMPA receptor activity, enhances synaptic plasticity, and improves learning and memory in rat models. Furthermore, PDE2 inhibitor6 possesses blood-brain barrier permeability.</p>
    Formula:C20H22F2N6O
    Color and Shape:Solid
    Molecular weight:400.425

    Ref: TM-T206498

  • Ro 0437626
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    Ro 0437626

    CAS:
    <p>P2X1 purinergic receptor antagonist</p>
    Formula:C27H35N5O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:525.66

    Ref: TM-T23241

  • Probenecid sodium
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    Probenecid sodium

    CAS:
    <p>Probenecid sodium is the sodium salt of Probenecid, a potent and selective agonist of transient receptor potential vanilloid 2 (TRPV2) channels. Additionally, Probenecid acts as an inhibitor of pannexin 1 channels.</p>
    Formula:C13H18NNaO4S
    Color and Shape:Solid
    Molecular weight:307.341

    Ref: TM-T204136

  • Metaphit methylsulfate
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    Metaphit methylsulfate

    CAS:
    <p>Metaphit methylsulfate is a specific PCP antagonist and an acylating agent for the [3H] phencyclidine binding site in rat brain homogenate. It inhibits PCP-induced motor activity through a presynaptic mechanism.</p>
    Formula:C19H28N2O3S2
    Color and Shape:Solid
    Molecular weight:396.567

    Ref: TM-T204740

  • EMD-95885
    Targetmol
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    EMD-95885

    CAS:
    <p>EMD-95885 is a selective antagonist of NMDA receptors containing NR2B subunits, with an IC50 of 3.9 nM. It does not interact with other sites on the NMDA receptor.</p>
    Formula:C22H23FN2O3
    Color and Shape:Solid
    Molecular weight:382.428

    Ref: TM-T205291