Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(100 products)
- Adiponectin receptor(5 products)
- CFTR(66 products)
- CGRP Receptor(54 products)
- Calcium Channel(544 products)
- Chloride channel(53 products)
- GABA Receptor(369 products)
- Monoamine Transporter(30 products)
- Monocarboxylate transporter(18 products)
- NKCC(2 products)
- NPC1L1(3 products)
- Na-K-Cl cotransporter(10 products)
- OAT(32 products)
- OCT(7 products)
- P-gp(55 products)
- Potassium Channel(283 products)
- Proton pump(41 products)
- SGLT(31 products)
- Sodium Channel(217 products)
- TRP/TRPV Channel(96 products)
Show 13 more subcategories
Found 2575 products of "Membrane Transporter/Ion Channel"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
epi-Aszonalenin A
CAS:epi-Aszonalenin A: a psychoactive benzodiazepine from Aspergillus novofumigatus.Formula:C25H25N3O3Color and Shape:SolidMolecular weight:415.4817α-Hydroxywithanolide D
<p>17alpha-Hydroxywithanolide D is an allosteric modulator of the NMDA receptor, with an IC50 of 44.24 nM. This compound exhibits neuroprotective properties and can be utilized in Alzheimer's disease research.</p>Formula:C28H46O7Color and Shape:SolidMolecular weight:494.661NT 13
CAS:<p>NT 13 is a partial N-methyl-D-aspartate receptor (NMDAR) agonist used in the study of depression, anxiety, and other related diseases.</p>Formula:C18H30N4O7Purity:98%Color and Shape:SolidMolecular weight:414.45ADWX 1
Potent KV1.3 blocker, IC50: 0.0019 nM; less effective on KV1.1. Curbs CD4+ T cell activation; eases rat multiple sclerosis model.Formula:C169H281N57O46S7Purity:98%Color and Shape:SolidMolecular weight:4071.86α5-GABAA receptor modulator 1
α5-GABAA receptor modulator 1 (Compound A-4) is a selective silent allosteric modulator (SAM) targeting the α5 subunit of GABAA receptors, useful for research into central nervous system (CNS) disorders.Formula:C21H20FN3O4Color and Shape:SolidMolecular weight:397.4P-gp inhibitor 23
<p>P-gp inhibitor 23 (compound 14F) is an effective inhibitor of both P-gp and CYP3A4, with an EC50 of 28 nM for P-gp and an IC50 of 223 nM for CYP3A4.</p>Formula:C40H37N5O6Molecular weight:683.27438α-Casozepine
CAS:α-Casozepine,Bioactive peptide from milk α-S1 casein. Binds GABA receptors. Anti-anxiety effects.Formula:C60H94N14O16Color and Shape:SolidMolecular weight:1267.47Apamin acetate
Apamin acetate: Selective Ca2+-activated K+ channel blocker, 18-amino acid bee venom peptide, promotes synapse repair, anti-inflammatory.Purity:96.97%Color and Shape:SolidATP Synthesis-IN-2
ATP Synthesis-IN-2 (Compound 5) serves as a potent inhibitor of ATP synthesis activity, displaying significant antibacterial properties with an IC50 value of 0.Color and Shape:Odour SolidMRS4596
MRS4596: selective P2X4 blocker, IC50 1.38 μM, neuroprotective in stroke research.Formula:C21H14N5NaO3SColor and Shape:SolidMolecular weight:439.42A 80915A
CAS:A80915A: Semi-naphthoquinone antibiotic, blocks gastric (H(+)-K+)-ATPase; potency varies with enzyme conformation; K+ reduces binding rate.Formula:C26H31Cl3O5Color and Shape:SolidMolecular weight:529.88Iberiotoxin
CAS:<p>Selective blocker of the big conductance Ca2+-activated K+ channel.</p>Formula:C179H274N50O55S7Purity:98%Color and Shape:SolidMolecular weight:4230Concanamycin B
CAS:Concanamycin B, a macrolide, inhibits V-ATPases (IC50 = 5 nM), blocks vacuole acidification, affects bone resorption, CD8 T cells, and MHC II in B cells.Formula:C45H73NO14Color and Shape:SolidMolecular weight:852.072Phe-Met-Arg-Phe, amide
CAS:Phe-Met-Arg-Phe amide activates K+ current in neurons (ED50=23 nM), co-localizes with neuropeptide Y in brain regions.Formula:C29H42N8O4SPurity:98%Color and Shape:SolidMolecular weight:598.76(Rac)-Tezacaftor
CAS:(Rac)-Tezacaftor, a racemate, corrects F508del CFTR for cystic fibrosis research.Formula:C26H27F3N2O6Color and Shape:SolidMolecular weight:520.5Resolvin D2
CAS:Resolvin D2 (RvD2) is a TRPV1 inhibitor and pro-ablative mediator with anti-inflammatory, anti-infective and pro-ablative effects.Formula:C22H32O5Purity:98%Color and Shape:SolidMolecular weight:376.49P-gp inhibitor 13
P-gp Inhibitor 13, a P-glycoprotein antagonist, can counteract paclitaxel resistance in A2780/T cells, proving valuable for advanced acute myeloid leukemiaFormula:C32H34O8Color and Shape:SolidMolecular weight:546.61Tariquidar dimesylate
CAS:Tariquidar, a non-competitive P-glycoprotein inhibitor, may help combat cancer drug resistance.Formula:C80H94N8O25S4Purity:98%Color and Shape:SolidMolecular weight:1695.9Antimalarial agent 41
Antimalarial agent 41 (Compound 17) exhibits antimalarial activity by inhibiting the malaria parasite Plasmodium falciparum, with IC50 values of 40 nM for NF54 strain and 76 nM for K1 strain. This compound acts as an inhibitor of P. falciparum phosphatidylinositol-4-kinase β (PfPI4K) and hERG channels, with IC50 values of 53 nM and 3 μM, respectively. Additionally, Antimalarial agent 41 shows cytotoxicity against CHO cells, with an IC50 of 34 μM. It can improve malaria infections and demonstrates favorable pharmacokinetic properties in mouse models.Formula:C19H18F3N5Molecular weight:373.151431-(aminomethyl)cyclopropanecarboxylic acid hydrochloride
CAS:<p>1-(aminomethyl)cyclopropanecarboxylic acid hydrochloride inhibits L amino acid transporter proteins and the α2δ subunit of voltage-gated calcium channels.1-(</p>Formula:C5H10ClNO2Purity:>99.99%Color and Shape:SolidMolecular weight:151.59
