Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(101 products)
- Adiponectin receptor(5 products)
- CFTR(65 products)
- CGRP Receptor(54 products)
- Calcium Channel(541 products)
- Chloride channel(53 products)
- GABA Receptor(365 products)
- Monoamine Transporter(30 products)
- Monocarboxylate transporter(18 products)
- NKCC(2 products)
- NPC1L1(3 products)
- Na-K-Cl cotransporter(10 products)
- OAT(32 products)
- OCT(7 products)
- P-gp(55 products)
- Potassium Channel(280 products)
- Proton pump(42 products)
- SGLT(31 products)
- Sodium Channel(209 products)
- TRP/TRPV Channel(95 products)
Show 13 more subcategories
Found 2514 products of "Membrane Transporter/Ion Channel"
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Antimalarial agent 41
Antimalarial agent 41 (Compound 17) exhibits antimalarial activity by inhibiting the malaria parasite Plasmodium falciparum, with IC50 values of 40 nM for NF54 strain and 76 nM for K1 strain. This compound acts as an inhibitor of P. falciparum phosphatidylinositol-4-kinase β (PfPI4K) and hERG channels, with IC50 values of 53 nM and 3 μM, respectively. Additionally, Antimalarial agent 41 shows cytotoxicity against CHO cells, with an IC50 of 34 μM. It can improve malaria infections and demonstrates favorable pharmacokinetic properties in mouse models.Formula:C19H18F3N5Molecular weight:373.15143Tertiapin
CAS:Tertiapin (reduced) is a synthetic bee venom peptide characterized by disulfide bonds between Cys3-Cys14 and Cys5-Cys18. It acts as an inhibitor of inward-rectifying potassium channels (potassium Channel) and can also block the activity of calcium-activated large conductance potassium channels. Tertiapin (reduced) is utilized in research related to diseases such as rheumatoid arthritis and multiple sclerosis.Formula:C106H180N34O23S5Color and Shape:SolidMolecular weight:2459.1Camegliptin
CAS:Cameglipti, a dipeptidyl peptidase IV (DPP-4) inhibitor, is used potentially for the treatment of type 2 diabetes.Formula:C20H28FN3O3Color and Shape:SolidMolecular weight:377.45Agitoxin-2
CAS:Potent Shaker K+ channel blocker (Ki = 0.64 nM). Also inhibits Kv1.3, Kv1.6 and Kv1.1 K+ channels (Ki values are 4, 37 and 44 pM respectively).Formula:C169H278N54O48S8Purity:98%Color and Shape:SolidMolecular weight:4090.87LY-466195
CAS:LY-466195 is a competitive antagonist of GLUK5 receptor.Formula:C16H24F2N2O4Color and Shape:SolidMolecular weight:346.37epi-Aszonalenin A
CAS:epi-Aszonalenin A: a psychoactive benzodiazepine from Aspergillus novofumigatus.Formula:C25H25N3O3Color and Shape:SolidMolecular weight:415.48α-Casozepine
CAS:α-Casozepine,Bioactive peptide from milk α-S1 casein. Binds GABA receptors. Anti-anxiety effects.Formula:C60H94N14O16Color and Shape:SolidMolecular weight:1267.47ADWX 1
Potent KV1.3 blocker, IC50: 0.0019 nM; less effective on KV1.1. Curbs CD4+ T cell activation; eases rat multiple sclerosis model.Formula:C169H281N57O46S7Purity:98%Color and Shape:SolidMolecular weight:4071.86PDZ1 Domain inhibitor peptide
CAS:Novel cyclic peptide that disrupts interaction between GluR6 and PSD-95Formula:C38H61N9O11Purity:98%Color and Shape:SolidMolecular weight:819.946-O-desmethyl Donepezil
CAS:6-O-desmethyl Donepezil, active Donepezil metabolite, inhibits acetylcholinesterase and hERG channels; formed by CYP2D6. IC50: 1.5 μM.Formula:C23H27NO3Color and Shape:SolidMolecular weight:365.47PptT-IN-4
PptT-IN-4 (Compound 3a) is a PptT inhibitor exhibiting an IC50 of 0.71 μM.Formula:C17H23N3Purity:98%Color and Shape:SolidMolecular weight:269.38ATP Synthesis-IN-2
ATP Synthesis-IN-2 (Compound 5) serves as a potent inhibitor of ATP synthesis activity, displaying significant antibacterial properties with an IC50 value of 0.Color and Shape:Odour SolidChrodrimanin B
CAS:Chrodrimanin B is a useful organic compound for research related to life sciences. The catalog number is T126052 and the CAS number is 132196-54-4.Formula:C27H32O8Color and Shape:SolidMolecular weight:484.545Iberiotoxin
CAS:<p>Selective blocker of the big conductance Ca2+-activated K+ channel.</p>Formula:C179H274N50O55S7Purity:98%Color and Shape:SolidMolecular weight:4230Monascorubrin
CAS:Monascorubrin, from Monascus purpureus mycelium, is an antibiotic against Bacillus subtilis and Candida pseudotropicalis.Formula:C23H26O5Color and Shape:SolidMolecular weight:382.45GYKI-47261 dihydrochloride
CAS:<p>GYKI-47261 dihydrochloride is an AMPA receptor antagonist and CYP2E1 inducer, demonstrating broad-spectrum anticonvulsant and neuroprotective activities.</p>Formula:C18H17Cl3N4Purity:98.32% - 99.14%Color and Shape:SolidMolecular weight:395.71Phe-Met-Arg-Phe, amide
CAS:Phe-Met-Arg-Phe amide activates K+ current in neurons (ED50=23 nM), co-localizes with neuropeptide Y in brain regions.Formula:C29H42N8O4SPurity:98%Color and Shape:SolidMolecular weight:598.76CW2158
CW2158 (Compound 13) is a modulator of exportin1 (XPO1). It disrupts chromatin binding and inhibits the activation of NFAT transcription factors and T cells.Formula:C14H8F4N4O2Molecular weight:340.05834Resolvin D2
CAS:Resolvin D2 (RvD2) is a TRPV1 inhibitor and pro-ablative mediator with anti-inflammatory, anti-infective and pro-ablative effects.Formula:C22H32O5Purity:98%Color and Shape:SolidMolecular weight:376.49NGD-8243
CAS:NGD-8243 (N-[4-(trifluoromethyl)phenyl]-7-[3-(trifluoromethyl)pyridin-2-yl]quinazolin-4-amine) is a TRPV1 inhibitor and can be used in studies for preventionFormula:C21H12F6N4Purity:95.26%Color and Shape:SolidMolecular weight:434.34
