Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(100 products)
- Adiponectin receptor(5 products)
- CFTR(65 products)
- CGRP Receptor(54 products)
- Calcium Channel(544 products)
- Chloride channel(53 products)
- GABA Receptor(369 products)
- Monoamine Transporter(30 products)
- Monocarboxylate transporter(18 products)
- NKCC(2 products)
- NPC1L1(3 products)
- Na-K-Cl cotransporter(10 products)
- OAT(32 products)
- OCT(7 products)
- P-gp(55 products)
- Potassium Channel(282 products)
- Proton pump(41 products)
- SGLT(31 products)
- Sodium Channel(214 products)
- TRP/TRPV Channel(96 products)
Show 13 more subcategories
Found 2562 products of "Membrane Transporter/Ion Channel"
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Mutabilol
Mutabilol boosts P-gp in NCI-H460/R cells; natural from Plectranthus mutabilis.Formula:C19H24O5Color and Shape:SolidMolecular weight:332.39Phrixotoxin 3
CAS:Potent NaV blocker: IC50 - 0.6 nM (NaV1.2), 42 nM (NaV1.3), 72 nM (NaV1.5); voltage-dependent inhibition.Formula:C176H269N51O48S6Purity:98%Color and Shape:SolidMolecular weight:4059.74ω-Agatoxin IVA
CAS:Selective blocker of P-type calcium channels (IC50 < 1 - 3 nM). Also inhibits N-type channels at micromolar concentrations.Formula:C217H360N68O60S10Purity:98%Color and Shape:SolidMolecular weight:5202.25CW2158
CW2158 (Compound 13) is a modulator of exportin1 (XPO1). It disrupts chromatin binding and inhibits the activation of NFAT transcription factors and T cells.Formula:C14H8F4N4O2Molecular weight:340.05834JTS-653
CAS:JTS-653 is a potent TRPV1 antagonist, effective in reducing chronic pain unresponsive to NSAIDs.Formula:C23H21F3N4O4Color and Shape:SolidMolecular weight:474.446-O-desmethyl Donepezil
CAS:6-O-desmethyl Donepezil, active Donepezil metabolite, inhibits acetylcholinesterase and hERG channels; formed by CYP2D6. IC50: 1.5 μM.Formula:C23H27NO3Color and Shape:SolidMolecular weight:365.47(-)-(S)-Cibenzoline
CAS:<p>Cibenzoline, also known as Escibenzoline, is the S(+)-enantiomer of Cibenzoline and functions as an antiarrhythmic agent.</p>Formula:C18H18N2Color and Shape:SolidMolecular weight:262.35Nav1.7-IN-8
CAS:Nav1.7-IN-8 selectively inhibits NaV1.7 over hNaV1.1/1.5, affects CYP2C9/3A4 (IC50: 0.17/0.077 μM), and provides rodent pain relief.Formula:C21H12ClF2N5O4S2Color and Shape:SolidMolecular weight:535.93Oleoyl-D-lysine
CAS:Oleoyl-D-lysine: lipid-based GlyT2 inhibitor, eases neuropathic pain in mice, safe, non-sedative, no respiratory depression.Formula:C24H46N2O3Color and Shape:SolidMolecular weight:410.63Transdermal Peptide Disulfide
CAS:TD 1 peptide, an 11-amino acid, binds ATP1B1's C-terminus, enhancing transdermal drug delivery.Formula:C40H64N14O16S2Purity:98%Color and Shape:SolidMolecular weight:1061.15ATP Synthesis-IN-2
ATP Synthesis-IN-2 (Compound 5) serves as a potent inhibitor of ATP synthesis activity, displaying significant antibacterial properties with an IC50 value of 0.Color and Shape:Odour SolidMRS4596
MRS4596: selective P2X4 blocker, IC50 1.38 μM, neuroprotective in stroke research.Formula:C21H14N5NaO3SColor and Shape:SolidMolecular weight:439.42P-gp inhibitor 23
<p>P-gp inhibitor 23 (compound 14F) is an effective inhibitor of both P-gp and CYP3A4, with an EC50 of 28 nM for P-gp and an IC50 of 223 nM for CYP3A4.</p>Formula:C40H37N5O6Molecular weight:683.27438Flavopereirine
CAS:Flavopereirine is a beta-carboline alkaloid.Formula:C17H15N2Color and Shape:SolidMolecular weight:247.31A-317567
CAS:A-317567 is a potent acid-sensing ion channel 3 (ASIC-3) inhibitor with an IC50 of 1.025 μM, and it has antidepressant and antinociception effects[1][2].Formula:C27H31N3Purity:98%Color and Shape:SolidMolecular weight:397.56Phe-Met-Arg-Phe, amide
CAS:Phe-Met-Arg-Phe amide activates K+ current in neurons (ED50=23 nM), co-localizes with neuropeptide Y in brain regions.Formula:C29H42N8O4SPurity:98%Color and Shape:SolidMolecular weight:598.76PptT-IN-4
PptT-IN-4 (Compound 3a) is a PptT inhibitor exhibiting an IC50 of 0.71 μM.Formula:C17H23N3Purity:98%Color and Shape:SolidMolecular weight:269.38Resolvin D2
CAS:Resolvin D2 (RvD2) is a TRPV1 inhibitor and pro-ablative mediator with anti-inflammatory, anti-infective and pro-ablative effects.Formula:C22H32O5Purity:98%Color and Shape:SolidMolecular weight:376.49Yaddle1
Yaddle1 is an agonist of the mechanically sensitive ion channel protein Piezo1, with a half-maximal effective concentration (MEC50) of 0.40 μM. It significantly induces Ca2+ influx in T cells, prompting T cell activation responses. Yaddle1 is applicable in vaccine adjuvant research.Formula:C14H8ClF3N4OSMolecular weight:372.00594c-Met-IN-23
c-Met-IN-23 (Compound 12g) functions as a c-Met inhibitor with an IC50 of 0.052 μM against c-Met. It also inhibits the MDR1 and MRP1/2 pumps in cancerous HepG2 and BxPC3 cells. As such, c-Met-IN-23 serves as an anticancer agent.Formula:C16H13N7OMolecular weight:319.11816
